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US20070154553 CUCURBITURIL-CONTAINING GEL AND METHOD OF PREPARING THE SAME  
Provided are a gel including a compound represented by Formula 1 below and a method of preparing the same: wherein n, X, A1, and A2 are as defined in the specification.
US20080075750 METHODS FOR PRODUCING THREE-DIMENSIONAL TISSUE-ENGINEERED CARDIAC CONSTRUCTS AND USES REGARDING SAME  
The invention relates generally to methods for producing a three-dimensional (3D) tissue-engineered cardiac construct and more specifically, a vascularized 3D tissue-engineered cardiac construct...
US20060142198 Compositions for treating wounds and processes for their preparation  
The present invention provides a process for obtaining growth factors by treating a growth factor starting material to release growth factors from the growth factor starting material and...
US20070161548 Use of adam 12 for diagnosis and therapy of preeclampsia  
The present invention relates to the significant role of ADAM 12, ADAM 12-L, and ADAM 12-S in preeclampsia and related disorders. The invention further relates to the use of said genes and gene...
US20130178418 NOVEL INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY, THEIR USES AND PROCESSES FOR THEIR PRODUCTION  
The present invention is directed to novel chimeric VEGF receptor proteins comprising amino acid sequences derived from the vascular endothelial growth factor (VEGF) receptors flt-1 and KDR,...
US20060111296 Plasmin-inhibitory therapies  
The disclosure features a method of treating cancers, angiogenesis-related disorders and lymphangiogenesis-related disorders with plasmin inhibitors. An exemplary method includes: administering,...
US20050267027 Use of erythropoietin for treatment of cancer  
A method for treating cancer is provided. The method involves administering to subjects in need of such treatment an effective amount of erythropoietin of an analog thereof effective to inhibit...
US20120130144 TREATMENT OF LUNG CANCER WITH A NITROBENZAMIDE COMPOUND IN COMBINATION WITH A GROWTH FACTOR INHIBITOR  
In one aspect, the present invention provides a method of treating lung cancer, comprising administering to a subject at least one PARP inhibitor in combination with at least one growth factor...
US20120015037 FUNCTIONALIZED NANOPARTICLE, METHOD FOR PREPARING THE SAME AND APPLICATION THEREOF  
The present invention relates to a new type of functionalized nanoparticles for drug delivery, comprising a type of polymer nanoparticles, a polymer stabilizer coating, and a drug, wherein said...
US20070110731 Integument Cell Regeneration Formulation  
The invention relates to a composition-of-matter and method of using a topical composition having 10-99 999% by weight of a topical base formulation and other active ingredients including stem...
US20060246033 Injectable bulking agent compositions  
Compositions comprising comminuted extracellular matrix material, a growth factor and a telocollagen are provided. The compositions are useful, for example, as injectable bulking agents....
US20100297238 Multifunctional and Biologically Active Matrices from Multicomponent Polymeric Solutions  
A functionalized electrospun matrix for the controlled-release of biologically active agents, such as growth factors, is presented. The functionalized matrix comprises a matrix polymer, a...
US20100130415 Stem cell secreted product derived compositions for wound treatment  
Compositions including formulations comprising secreted products obtained from the culture medium of stem cells, such as umbilical cord blood stem cells, or embryonic germ cell derivatives, or...
US20110217260 METHOD OF ENHANCING EYELASH AND EYE BROW HAIR GROWTH  
A method of enhancing eyelash and eye brow hair growth utilizes insulin and/or IFG-1 alone or in combination with other known hair growth promoting therapeutic, pharmaceutical, biochemical and...
US20140056989 VIRAL INACTIVATED PLATELET EXTRACT, USE AND PREPARATION THEREOF  
The invention relates to a viral-safe platelet extract, to its preparation and use. The extract comprises a mixture of biologically active platelet derived factors. Advantageously, the extract...
US20120156306 VIRAL INACTIVATED PLATELET EXTRACT, USE AND PREPARATION THEREOF  
The invention relates to a viral-safe platelet extract, to its preparation and use. The extract comprises a mixture of biologically active platelet derived factors. Advantageously, the extract...
US20050215499 Lipoproteins as nucleic acid vectors  
The present invention relates to materials and methods for the in vivo transport and deliver of nucleic acids. More particularly, it concerns the use of lipoproteins, including but not limited to,...
US20120141424 Materials and Methods for the Treatment of Hypertension  
The present invention is directed to materials and methods for the treatment of hypertension and ischemia comprising administering at least one therapeutic agent selected from the group consisting...
US20070248641 Use of Del-1 in Hair, Bone and Cartilage Regeneration  
Methods and compositions are described enhancing bone density or formation, including for stabilizing bone grafts, bone repair, joint replacement, and cartilage repair that includes providing a...
US20070184021 Use of caspase inhibitors as a therapeutic agent against radiation-induced injury  
The present invention provides methods for the treatment of radiation-induced injury by providing to a subject a caspase inhibitor. The caspase inhibitor may be provided before or after the...
US20120070485 METHOD FOR PRODUCING A DEVICE APPLICABLE TO BIOLOGICAL TISSUES, PARTICULARLY A PATCH FOR TREATING DAMAGED TISSUES, AND A DEVICE OBTAINED BY SAID METHOD  
The present invention relates to a device consisting of cross-linked nanofibrillary fibrin supported on and rooted to a microporous nonwoven fabric consisting of a biocompatible synthetic polymer...
US20120219629 COMPOSITIONS AND METHODS FOR CONTROLLED DELIVERY OF COMPOUNDS  
Disclosed are methods, compositions and kits pertaining to controlled delivery of compounds. In certain aspects and embodiments the present technology relates to compositions and methods for...
US20060045880 Methods for modulating angiogenesis and apoptosis with apelin compositions  
Novel methods of inhibiting angiogenesis or tumorigenesis or promoting apoptosis with compositions that inhibit the apelin/APJ signaling pathway are provided. Also provided are methods of...
US20130130980 Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors  
The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention...
US20110052715 NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF  
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric nanoparticle form of thyroid hormone agonist,...
US20090018062 Malignant tumor-inhibiting preparation comprising des a fibrin  
A malignant tumor-inhibiting preparation is provided which comprises Des A fibrin and therefore can inhibit the spreading and migration of malignant tumor cells and thereby can inhibit the...
US20070161552 Use of low-dosage erythropoietin for stimulation of endothelial progenitor cells, for organ regeneration and for slowing the progression of end-organ damage  
The present invention relates to the use of low-dosage erythropoietin for stimulation of physiological mobilization, proliferation and differentiation of endothelial progenitor cells, for...
US20120238495 Novel Cellular Factor-Containing Solution Compositions  
The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing...
US20120225815 Novel Cellular Factor-Containing Solution Compositions  
The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing...
US20120101036 Novel cellular factor-containing solution compositions  
The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing...
US20150086599 Self Assembled Films for Protein and Drug Delivery Applications  
Provided are systems for controlled release of proteins from decomposable thin films constructed by layer-by-layer deposition. Such films generally comprise alternating layers of polymers and...
US20110020229 Multi-Component Biological Transport Systems  
Compositions and methods are provided that are useful for the delivery of therapeutic agents, including nucleic acids. The compositions can be prepared with components useful for targeting the...
US20110020338 5Imidazoquinolines and Pyrimidine Derivatives as Potent Modulators of VEGF-Driven Angiogenic Processes  
The invention relates to the use of compounds of formula (I) or (II) in the treatment of mammalian target of VEGF-driven angiogenic diseases, methods of use of said compounds in the treatment of...
US20060257449 Methods, compositions, systems, and devices for bone fusion  
The present invention is directed to methods, compositions, systems, and medical devices for fusing bone.
US20080050415 Polymeric/ceramic composite materials for use in medical devices  
According to an aspect of the invention, implantable or insertable medical devices are provided, which contain one or more composite regions. These composite regions, in turn, contain (a) a...
US20070059336 Anti-angiogenic sustained release intraocular implants and related methods  
Biocompatible intraocular drug delivery systems include a anti-angiogenic therapeutic agent and a polymeric component in the form of an implant, a microparticle, a plurality of implants or...
US20120258915 Proteolysis Resistant Active VEGF  
The invention relates to endothelial growth factor (VEGF) in which the alanine at AA position 111 is replaced by proline. The arginine at AA position 110 may moreover be replaced by another amino...
US20110009316 PROTEOLYSIS RESISTANT ACTIVE VEGF  
The invention relates to endothelial growth factor (VEGF) in which the alanine at AA position 111 is replaced by proline. The arginine at AA position 110 may moreover be replaced by another amino...
US20150231246 COMPOSITION FOR FORMING PLURONIC-BASED HYDROGEL WITH IMPROVED STABILITY  
Disclosed is a composition for forming an injectable hydrogel. The composition includes 1% by weight or less of a graphene-based material and 5% by weight or more of a triblock copolymer. The...
US20070099832 Combination Therapy with p38 MAP Kinase Inhibitors and their Pharmaceutical Compositions  
The present invention relates to pharmaceutical combinations therapies based on p38 kinase inhibitors and another active ingredient, pharmaceutical compositions comprising such combinations,...
US20070072793 Histone hyperacetylating agents for promoting wound healing and preventing scar formation  
A method for promoting wound healing and preventing scar formation in a variety of wounds in skin, mucosa, and cornea. The method comprises administering a therapeutically effective amount of a...
US20140037708 COMPOSITION FOR SPATIO AND/OR TEMPORAL RELEASE OF BIOACTIVE MATERIAL  
The present invention provides a biocompatible composition that comprises a bioactive material and a method for using the same. In particular, the composition of the invention is useful for spatio...
US20070154552 Biologically active native biomatrix composition  
The present disclosure relates to a biologically active biomatrix composition. In one embodiment, the biomatrix composition is derived from human amnions. The biomatrix is termed HuBiogel™. The...
US20080227699 Therapeutic Agent for Neurodegenerative Diseases  
The present invention relates to a pharmaceutical composition for the treatment and/or prevention of a neurodegenerative disease, comprising the following polypeptide shown in any of (a) to (c):...
US20130195885 Compositions with Hematopoietic and Immune Activity  
The present invention provides methods of using Bv8 and EG-VEGF polypeptides and nucleic acids to promote hematopoiesis. Also provided herein are methods of screening for modulators of Bv8 and...
US20070212404 Liposome And Method Of Preparing The Same  
Provided are a liposome formed by self-assembling a cucurbituril derivative and a method of preparing the liposome.
US20070141101 Method for stimulating angiogenesis and wound healing  
A device comprising an extracellular matrix having an internal pH between 4.0 and 6.0 is discussed. This matrix contains heparin or a heparin-related compound such as heparan sulfate. Preferably...
US20130195781 Modified Variant Bowman Birk Protease Inhibitors  
The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater...
US20140148386 Method for prevention or treatment of diabetic vascular leakage-induced disease using C-peptide  
Disclosed is a method for the prevention or treatment of vascular leakage-induced diseases and diabetic retinopathy, using C-peptide. Found to prevent extravascular leakage by inhibiting...
US20100254999 EG-VEGF NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USE  
The present invention is directed to novel polypeptides designated herein as EG-VEGF and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells...