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US20090149510 |
Compositions and methods for modulating a kinase cascade
The invention relates to compounds and methods for modulating one or more components of a kinase cascade.
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US20090143334 |
Method of Protecting Wood Through Enhanced Penetration of Wood Preservatives and a Related Solution
A method of protecting wood through enhanced penetration of wood preservatives includes providing a solution including (a) at least one amine oxide. (b) at least one organic wood preservative and...
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US20090131536 |
Treating or Preventing Renal Cancer Using a Dimethane Sulfonate
The present invention features methods of treating renal cancer by administration of certain dimethylsulfonate compounds. The present invention further features administration protocols and dosing...
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US20090131419 |
Sulphones which modulate the action of gamma secretase
Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.
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US20090068197 |
MYCOBACTERIAL DISEASE DETECTION, TREATMENT, AND DRUG DISCOVERY
Methods for detecting and treating Mycobacterium -related diseases including reducing Mycobacterial virulence, reducing RV3133c dimerization, and treating a subject with a Mycobacterial infection...
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US20080269350 |
ST104P, AN ANTI-ANGIOGENIC AGENT
The present invention relates to a method of treating a non-tumor condition or disease associated with angiogenesis in a human or animal comprises administering thereto an effective angiogenesis...
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US20080255232 |
Naphthyl Derivatives as Inhibitors of Beta-Amyloid Aggregation
Compounds useful in the treatment of disorders characterized by deposits of amyloid aggregates are herein described together with pharmaceutical compounds containing the same. In particular the...
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US20080249136 |
Antimicrobial Composition and Method
An antimicrobial composition containing a cationic polymer having limited antimicrobial activity (such as a hydrophobically-modified quaternary ammonium cellulose ether) and an antimicrobial...
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US20080220067 |
ANTIMICROBIAL ADHESIVE SYSTEM
An adhesive composition having dispersed therein a broad spectrum antimicrobial agent for use in medical applications, such as an adhesive for surgical drapes, wound dressings and tapes, is...
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US20080161252 |
Composition and Methods For the Treatment of Proliferative Diseases
Methods and compositions are provided for treating proliferative disorders, wherein the composition comprises at least one compound according to Formula I:
wherein R 1 is selected from the...
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US20080118591 |
Bactericidal Formulations
The invention relates to bactericidal formulations that come into contact with human body, particularly wash formulations including liquid soaps, comprising perfume ingredients active against...
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US20080114075 |
Use of 2,5-Dihydroxybenzene Derivatives for Treating Dermatitis
The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the...
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US20080075692 |
METHODS FOR TREATING BLOOD DISORDERS
Methods of treating blood disorders are described.
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US20080070974 |
Alpha, Beta-Unsaturated Sulfones, Sulfoxides, Sulfonimides, Sulfinimides, Acylsulfonamides and Acylsulfinamides and Therapeutic Uses Thereof
α,β-Unsaturated sulfones, sulfoxides, sulfonimides, sulfinimides, acylsulfonamides and acylsulfinamides of Formula I:
wherein R 1 , R 2 , M 1 , M 2 , L, E 1 , E 2 , Q 1 , Q 2 and n are as...
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US20080058290 |
Substituted Phenoxy-and Phenylthio-Derivatives for Treating Proliferative Disorders
Substituted phenol derivatives of Formula (I) are useful as antiproliferative agents including, for example, anticancer agents, and as radioprotective and chemoprotective agents.
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US20080045602 |
Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine
A new process for preparation of 3-(2-hydroxy-5-methylphenyl)-N,N-diisopropyl-3-phenylpropyla
mine from 3,4-dihydro-6-methyl-4-phenyl-2-benzopyran-2-one is characterized by intermediates such as...
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US20080045533 |
Novel cyclohexyl sulphones
Novel sulphones of formula I are disclosed:
The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of...
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US20080027025 |
Protection From And Treatment Of Prion Protein Infection
The disclosure for the first time provides an understanding of the mechanism of prion protein infection: prion proteins contain a cationic protein transduction domain (PTD) that interacts with the...
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US20080020973 |
Assays for identification of topoisomerase inhibitors
The instant invention provides a continuous spectroscopic assay for DNA topoisomerase activity. The invention further provides topoisomerase inhibitors and pharmaceutical compositions for the...
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