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US20090149551 |
OXIDIZED cis-TERPENONE AND ITS USE AS A CHEMOPROTECTIVE AND ANTI-MALARIAL AGENT
4 b ,5,6,7,8,8 a -cis-hexahydro-2-hydroxy-4 b ,8,8 a -trimethylphenanthren-9,10-dione (OHCT) is a fully oxidized compound based on the 2-hydroxy-cis-terpenone (HCT). Because OHCT is fully oxidized,...
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US20090137687 |
Compositions and Methods With Enhanced Therapeutic Activity
This invention relates to novel tricyclic quinone and catechol compositions, compositions containing prodrugs of tricyclic quinone and catechol compositions, and methods of use for the treatment of...
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US20090117040 |
Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases
The present invention relates to pharmaceutical and diagnostic compositions as well as to the use of the active substances contained therein for preparing a pharmaceutical or a diagnostic...
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US20090110731 |
Loadable Polymeric Microparticles for Therapeutic Use in Alopecia and Methods of Preparing and Using the Same
Particles are provided for use in restorative procedures to treat and/or retard alopecia The particles include poly[bis(trifluoroethoxy)phosphazene] and/or a derivatives thereof which may be...
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US20090099251 |
DIETARY AND PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES
The present invention refers to tricyclic diterpenes and their derivatives of the formulae (I) and (II), wherein R 1 is hydrogen or C 1-6 -alkyl; R 2 is hydroxy, C 3-5 -acyloxy, hydroxymethyl,...
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US20090082470 |
STAT3 INHIBITING COMPOSITIONS AND METHODS
STAT 3 inhibiting molecules and composition prevent intraoccular neovascularization and inflammation. STA-21-related compounds, for example CLT-005, are shown to prevent dimerization of STAT 3 ,...
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US20090068143 |
ORALLY EFFECTIVE CANNABINOID ANALOGS
The present invention relates to orally effective ligands of the peripheral cannabinoid receptor CB 2 , especially (+)-α-pinene derivatives, and to pharmaceutical compositions thereof, which are...
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US20080226759 |
SYSTEM FOR TREATING ADDICTIONS
A system for treating addictions includes genetic testing to determine the presence of allelic variants of genes shown to be associated with impulsive/addictive behaviors and a tailored...
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US20080201871 |
ANTIMICROBIAL COLORANTS
Quaternary ammonium salts were incorporated into anthraquinone dyes via a stable linkage. The structure of the antimicrobial colorants were characterized by Fourier Transform Infrared (FTIR),...
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US20080161372 |
Methods for the Treatment of Hypertension
This invention relates to the treatment of hypertension, cardiac dysfunction or stroke by the administration of an estrogen receptor beta (ERβ) selective agonist either as a single agent, or in...
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US20080103160 |
Protein phosphatase inhibitors
A method of inhibiting protein tyrosine phosphatase in a subject includes administering to the subject a therapeutically effective amount of at least one benzo-1,4-quinone, phenyl isothiazolone, or...
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US20080102089 |
Topical and transdermal treatments using urea formulations
Various medical conditions previously treated by injection or surgery are effectively treated by a topical application of a composition of urea and a chemotherapeutic agent. Such agents include...
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US20080090772 |
Oligosaccharide Aldonic Acids and Their Topical Use
Compositions comprising oligosaccharide aldonic acids are useful for general care, as well as for treatment and prevention, of various cosmetic conditions and dermatological disorders, including...
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US20080058322 |
Small molecule inhibitors targeted at Bcl-2
The present invention relates to small molecule antagonists of Bcl-2 family proteins such as Bcl-2 and/or Bcl-X L . In particular, the present invention provides non-peptide cell permeable small...
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US20080051463 |
ANTHRACENE COMPOUNDS AND THEIR USE FOR TREATING BENIGN AND MALIGNANT TUMOR DISORDERS
The present invention provides novel anthracene compounds according to the formulae (I) and (II) and also selected anthracene compound compounds. The present invention furthermore provides a...
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US20080027141 |
1,3-Dihydroxyl-9,10-anthraquinone and 3-[(3-amino)-propoxy]- 9,10-anthraquinone derivatives and pharmaceutical compositions comprising the same
Disclosed herein are 1,3-dihydroxyl-9,10-anthraquinone and 3-[(3-amino)-propoxy]-9,10-anthraquinone derivatives, in particular 1,3-dihydroxy-4-prenyl-9,10-anthraquinone and...
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