Matches 1 - 50 out of 55 1 2 >


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US20140088083 USE OF MEMANTINE (NAMENDA) TO TREAT AUTISM, COMPULSIVITY, AND IMPULSIVITY  
The present invention relates to the treatment of compulsive, impulsive and pervasive developmental disorders. More particularly, the methods described herein comprise administration of memantine...
US20130253067 METHOD OF TREATING BLADDER DISORDERS  
The present invention relates to dexmecamylamine and the use of dexmecamylamine, substantially free of exo-R-mecamylamine, in the treatment of bladder disorders, including overactive bladder.
US20130231290 METHODS OF DIAGNOSING AND TREATING NEURODEGENERATIVE DISEASES  
The present invention relates to methods of diagnosing, treating and prognosing mental disorders, such as Alzheimer's Disease. In one embodiment, the present invention provides a method of...
US20110059169 Method and Composition for Administering an NMDA Receptor Antagonist to a Subject  
The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.
US20110294785 INFLUENZA A VIRUS INHIBITION  
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza...
US20120028906 METHOD FOR AFFECTING THE TIMING OF CERVICAL RIPENING AND FOR PARTURITION  
A method for affecting the timing of cervical ripening and the resultant onset of parturition in a pregnant female mammal, the method comprises administering to a pregnant female one or more than...
US20110281955 METHODS OF TREATING OBESITY USING ANTIOXIDANT INFLAMMATION MODULATORS  
The present invention relates to methods of treating and/or preventing obesity comprising the administration of antioxidant inflammation modulators described herein, including for example...
US20110165252 MEMANTINE FORMULATIONS  
The present invention relates to pharmaceutical compositions prepared from equant-shaped crystals of memantine, such as orally dissolving formulations, e.g., tablets (ODTs) and films (ODFs), and...
US20140194525 EXO-S-MECAMYLAMINE FORMULATION AND USE IN TREATMENT  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
US20110028565 EXO-S-MECAMYLAMINE FORMULATION AND USE IN TREATMENT  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
US20130030057 METHODS AND COMPOSITIONS COMPRISING AT LEAST ONE ALPHA3 BETA4 nAChR ANTAGONIST OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF  
The present invention is directed to methods and formulations for treating, modifying, and/or managing gastrointestinal secretion, and intestinal conditions that cause the same. Methods of using...
US20140315877 NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS  
The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.
US20140288169 NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS  
The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for their use, and their pharmaceutical compositions.
US20130203860 NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS  
The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.
US20100040679 Compositions for Reducing Nicotine Withdrawal Symptoms and/or Tobacco Usage  
Compositions useful for treating an individual with nicotine dependence comprising a combination of an α3β4 nicotinic receptor antagonist and a nicotine metabolite are disclosed. More...
US20090076165 DEUTERIUM-ENRICHED MEMANTINE  
The present application describes deuterium-enriched memantine, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
US20120028957 Inhibitors Of The Influenza A Virus M2 Proton Channel  
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza...
US20100048726 Memantine For The Treatment Of Mild And Mild To Moderate Alzheimer's Disease  
The present invention provides a method for the treatment, prevention, or delay of progression of mild, or mild-to-moderate Alzheimer's disease, by administering an effective dose of memantine....
US20080249082 Use of Memantine (Namenda) to Treat Autism, Compulsivity and Impulsivity  
The present invention relates to the treatment of compulsive, impulsive and pervasive developmental disorders. More particularly, the methods described herein comprise administration of memantine...
US20120269906 TREATMENT OF SUICIDAL IDEATION OR BEHAVIOR USING INHIBITORS OF NICOTINIC ACETYLCHOLINE RECEPTORS  
The invention concerns methods of treating suicidal ideation or behavior in a subject in need thereof, comprising decreasing endogenous nicotinic acetylcholine receptor (nAChR) activity in the...
US20080182908 PHARMACEUTICAL COMPOSITIONS COMPRISING MEMANTINE  
Pharmaceutical compositions comprising memantine or a salt thereof, from which less than about 80% of the contained memantine dissolves into a pH 1.2 aqueous medium within about 60 minutes.
US20130210904 SYNTHESIS OF BICYCLIC COMPOUNDS AND METHOD FOR THEIR USE AS THERAPEUTIC AGENTS  
Disclosed embodiments concern the synthesis and use of therapeutic compounds that for treating emerging flu strains and minimizing resistance to such strains. Methods for making the disclosed...
US20070224284 Methods and compositions comprising at least one alpha3 beta4 nAChR antagonist or pharmaceutically acceptable salt thereof  
The present invention is directed to methods and formulations for treating, modifying, and/or managing gastrointestinal secretion, and intestinal conditions that cause the same. Methods of using...
US20140275245 BICYCLIC ANALGESIC COMPOUNDS  
Analgesic compounds for treatment of pain or fever, comprising a bicyclopentane moiety linked to an amine, combinations of the compounds with opioid analgesic drugs, and methods for treating pain...
US20100286282 EXO-S-MECAMYLAMINE FORMULATION AND USE IN TREATMENT  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
US20100196479 METHODS AND COMPOSITIONS COMPRISING AT LEAST ONE ALPHA3 BETA4 nAChR ANTAGONIST OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF  
The present invention is directed to methods and formulations for treating, modifying, and/or managing gastrointestinal secretion, and intestinal conditions that cause the same. Methods of using...
US20120122993 PHARMACEUTICAL COMPOSITION CONTAINING 1H-INDEN-1-AMINE, 2,3-DIHYDRO-N-2-PROPYNYL-(1R)-, METHANESULFONATE  
A pharmaceutical composition comprising as an active ingredient a therapeutically effective amount of R(+)-N-propargyl-1-aminoindan mesylate thereof, and less than 50% by weight of hexahydric...
US20120190752 EXO-S-MECAMYLAMINE METHOD, USE, AND COMPOUND FOR TREATMENT  
The present invention relates to exo-S-mecamylamine and the use of exo-S-mecamylamine in medical treatments.
US20140057877 Therapeutic polyamine compositions and their synthesis  
This invention relates to a process of synthesis and composition of open chain (ring), closed ring, linear branched and or substituted polyamines, polyamine derived tyrosine phosphatase inhibitors...
US20080089861 Combination therapy for treatment of demyelinating conditions  
The invention provides compositions and methods for treating autoimmune diseases such as multiple sclerosis. The compositions include a combination of an NMDA Receptor antagonist, such as...
US20080026060 CONTROLLED-RELEASE PHARMACEUTICAL TABLETS  
Controlled-release tablets exhibiting excellent storage stability are achieved by granulating a pharmaceutically active agent with a hydroxyalkylcelluose, blending the resulting granules with an...
US20140371252 INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS  
Processes for making and using compounds of formula (I): wherein R1, R2, R3, R4a, R4b, R5 and R6 are defined herein, as well as other indene derivatives are disclosed herein. These compounds are...
US20070270443 Methods and compositions for the treatment of viral infections  
Compositions for treating flu comprise an M2 inhibitor, and optionally a neuraminidase inhibitor, wherein at least one of said M2 inhibitor or said neuraminidase inhibitor is provided in an...
US20090208579 Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same  
A matrix type sustained-release preparation and a manufacturing method therefor are provided wherein dissolution with low pH dependence of a basic drug or a salt thereof at the early stage of...
US20080176953 Methods and compositions for treatment of ocular neovascularization and neural injury  
Methods and compositions for the treatment of ocular neovascularization and macular degeneration. The invention includes combining photodynamic therapy with administration of a neuroprotectant and...
US20120115917 COMBINATION THERAPY FOR THE MANAGEMENT OF HYPERTENSION  
The present invention includes a combination comprising: a) mecamylamine; and b) an ACE inhibitor, an AT2 receptor inhibitor, a renin inhibitor, or a combination thereof.
US20080107719 Transdermal drug delivery system  
A transdermal drug delivery system includes a drug source, an adhesive for applying the system to a skin surface, a penetration enhancer for enhancing penetration of the drug into the skin...
US20120270901 INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS  
Compounds of formula (Ia): wherein R1, R2, R3, R4a, R4b, R5, and R6 are defined herein, as well as other indene derivatives are disclosed herein. Pharmaceutical compositions containing the...
US20110009439 INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS  
Compounds of formula (Ia): wherein R1, R2, R3, R4a, R4b, R5, and R6 are defined herein, as well as other indene derivatives are disclosed herein. Pharmaceutical compositions containing the...
US20110118307 Compositions and methods for the treatment of infectious diseases  
Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the...
US20150017227 Methods and Compositions for Treating Skin Diseases and Conditions  
Disclosed are methods and compositions for treating skin diseases or conditions with a composition containing a lipid component as an active ingredient.
US20140066408 ANTIOXIDANT INFLAMMATION MODULATORS: C-17 HOMOLOGATED OLEANOLIC ACID DERIVATIVES  
This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits...
US20090124659 Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase and inhibitors  
The invention relates to a novel drug combination therapy useful in the treatment of dementia comprising administering an 1-aminocyclohexane derivative such as memantine or neramexane and an...
US20140073700 GLYCYRRHETINIC ACID DERIVATIVES AND METHODS OF USE THEREOF  
The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein Y and Z are as defined in the specification; (b) compositions comprising such compounds and salts; and...
US20140088188 C13-HYDROXY DERIVATIVES OF OLEANOLIC ACID AND METHODS OF USE THEREOF  
Disclosed herein are novel C13-hydroxy derivatives of oleanolic acid, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits...
US20080009546 Diamondoid derivatives possessing therapeutic activity in the treatment of neurologic disorders  
This invention relates to diamondoid derivatives which exhibit therapeutic activity. Specifically, the diamondoid derivatives herein exhibit therapeutic effects in the treatment of neurologic...
US20170181983 EXO-S-MECAMYLAMINE FORMULATION AND USE IN TREATMENT  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
US20170071878 NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS  
The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.
US20160194631 Methods for Modulation of Autophagy Through the Modulation of Autophagy-Inhibiting Gene Products  
The present disclosure relates to methods for the modulation of autophagy and the treatment of autophgy-related diseases, including cancer, neurodegenerative diseases and pancreatitis.
US20160151307 AMANTADINE COMPOSITIONS AND METHODS OF USE  
Methods of nighttime administration of amantadine to reduce sleep disturbances in patient undergoing treatment with amantadine are described, as well as compositions of extended release amantadine...

Matches 1 - 50 out of 55 1 2 >