Matches 1 - 50 out of 279 1 2 3 4 5 6 >


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US20150086565 CANCER-RELATED EXTRACELLULAR MATRIX SIGNATURES AND RELATED METHODS AND PRODUCTS  
Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with...
US20150017226 TOLTERODINE-CONTAINING ADHESIVE PATCH  
The present invention provides a tolterodine-containing patch in which an adhesive layer is laminated on a backing, characterized in that the adhesive layer is obtainable by adding tolterodine to...
US20140073611 METHODS FOR DRUG SCREEN USING ZEBRAFISH MODEL AND THE COMPOUNDS SCREENED THEREFROM  
The disclosure relates to a platform of using zebrafish in screening candidates for treating and/or preventing myopia and keratoconus disease. The disclosure is mainly based on that Lumican, one...
US20110015134 Method of treatment for early stage cancer  
This patent describes a method and materials to treat cancer diagnosed at an early stage, particularly breast cancer. It considers that metastatic breast cancer growth includes periods of...
US20110229468 TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER  
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of...
US20110229467 TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER  
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of...
US20110206666 TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER  
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of...
US20110150979 METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES  
In one embodiment, a method of theranostic classification of a breast cancer tumor is provided, comprising obtaining a breast cancer tumor sample from a subject, detecting an expression level of...
US20140314750 Six-Gene Biomarker of Survival and Response to Platinum Based Chemotherapy in Serious Ovarian Cancer Patients  
Described herein are methods of predicting the risk of developing ovarian cancer recurrence of a subject comprising the steps of detecting the expression levels of at least four of the six genes...
US20110268820 USE OF SELECTIVE ESTROGEN RECEPTOR MODULATOR FOR JOINT FUSION AND OTHER REPAIR OR HEALING OF CONNECTIVE TISSUE  
Methods for facilitating joint immobilization or fusion using selective estrogen receptor modulator (SERM) such as raloxifene are disclosed. The SERM may be administered systemically or locally....
US20110118313 IDENTIFICATION OF A MOLECULAR SIGNATURE FOR ANTIPSYCHOTICS AND SERMS  
Molecular signature for antipsychotics and SERMs has been identified, namely their upregulation of genes that alter lipid homeostasis, preferably of one or more of the following genes: TNSIG1,...
US20110200695 GEL COMPOSITION FOR FILLING A BREAST MILK DUCT PRIOR TO SURGICAL EXCISION OF THE DUCT OR OTHER BREAST TISSUE  
The invention is a gel composition for delivery to a breast milk duct prior to surgical excision of breast tissue including cancerous lesions. The invention also provides methods of mapping all or...
US20130272963 Cholesterol Efflux Assay Probe Formulations, Methods of Making and Using  
A cholesterol efflux assay probe formulation having a core comprised of a biocompatible hydrophobic material at least partially coated with a sphingomyelin/cholesterol layer, methods of making and...
US20130142845 USE OF A COMBINATION OF AN OPIOID AGONIST AND AN OPIOID ANTAGONIST FOR THE TREATMENT OF CROHN'S DISEASE AND THE SYMPTOMS ASSOCIATED WITH CROHN'S DISEASE  
The present invention is concerned with the use of combinations of opioid agonists and antagonists for treating Crohn's disease.
US20110142939 Use of a Combination of an Opioid Agonist and an Opioid Antagonist for the Treatment of Crohn's Disease and the Symptoms Associated with Crohn's Disease  
The present invention is concerned with the use of combinations of opioid agonists and antagonists for treating Crohn's disease.
US20110280909 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE  
Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are...
US20150174084 Stable Liquid Medication Containing Diphenhydramine  
A chemically stable liquid medication that contains diphenhydramine hydrochloride and has a pH of greater than about 4.5. The liquid medication contains less than about 1.5% of BZH based on parent...
US20120157542 METHOD TO ASSESS PROGNOSIS AND TO PREDICT THERAPEUTIC SUCCESS IN CANCER BY DETERMINING HORMONE RECEPTOR EXPRESSION LEVELS  
The present invention is related to a method of classifying a sample of a patient who suffers from or being at risk of developing cancer, said method comprising the steps of determining in said...
US20110086800 SCREENING METHOD FOR PREDICTING SUSCEPTIBILITY TO BREAST CANCER  
A method to aid in identifying a familial or sporadic pattern of risk in at least one individual for developing cancer of a mucosal epithelial tissue, the method comprising screening said at least...
US20140093560 METHODS AND MATERIALS FOR THE TREATMENT OF TESTOSTERONE DEFICIENCY IN MEN  
The present invention relates to the use of compositions comprising trans-clomiphene for treating men with hypogonadism. The invention is also directed to methods for treating males with hypogonadism.
US20110289605 Animal Model for Osteoarthritis and Intervertebral Disc Disease  
Provided herein is a transgenic animal whose genome comprises a first nucleic acid sequence encoding a fusion polypeptide, wherein the fusion polypeptide comprises a Cre recombinase and a mutated...
US20110244051 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF OVERACTIVE BLADDER  
Disclosed herein are pharmaceutical compositions comprising a plurality of first beads each comprising: a core; a first layer comprising pilocarpine or a pharmaceutically acceptable salt thereof;...
US20130023488 METHODS AND COMPOUNDS FOR REDUCING INTRACELLULAR LIPID STORAGE  
Compounds and compositions for reducing intracellular lipid accumulation in a cell are described herein. These compounds are useful for the treatment and prevention of lipid/glycogen disorders, as...
US20150196531 Methods and Compositions For Treating Sleep-Related Breathing Disorders  
Provided herein are methods of treating a sleep-related breathing disorder, such as obstructive sleep apnea, comprising the administration of O-desmethylvenlafaxine or duloxetine.
US20140350117 Topical Scar Treatment Composition and Method of Using Same  
The present disclosure describes a topical scar treatment composition that may include tamoxifen citrate in a concentration of about 0.01% by weight to about 1% by weight, with about 0.1% by...
US20120270947 Short Telomere Length on Chromosome 9P is Strongly Associated with Breast Cancer Risk  
Disclosed are compositions and methods related to assessing the risk of cancer, such as breast cancer, through analyzing the length of telomeres, such as chromosome 9p telomere, such as the short...
US20150154881 Method for a Wellbeing Therapy Program  
As one implementation example, a method for comforting and helping an addicted user is described which comprises referencing a first portion of an informational composition, the first portion...
US20090036415 Identification and treatment of estrogen responsive prostate tumors  
The present invention is directed to specific chromosomal rearrangements that are associated with prostate tumors that respond to compounds acting at estrogen receptors. Patients having the...
US20150111970 GENETIC MARKERS AND DIAGNOSTIC METHODS FOR RESISTANCE OF BREAST CANCER TO HORMONAL THERAPIES  
This application provides a method to identify genetic markers associated with increased sensitivity or resistance to hormonal therapies using an outlier analysis. More specifically, this...
US20130195957 PATCH AND METHOD FOR ENHANCING ADHESION FORCE OF THE SAME  
A patch comprising a support and an adhesive agent layer, wherein the adhesive agent layer comprises at least one selected from the group consisting of tolterodine acetate and salts thereof.
US20120245231 Weight based dosing of an oral solution having diphenhydramine, or pharmaceutically acceptable salts thereof, as an active ingredient  
The present invention is directed toward a method of administering an oral solution containing one or more active ingredients, preferably formulations for non-prescription medicines, vital fluids,...
US20130281491 FORMULATIONS AND DELIVERY  
The invention provides pharmaceutical compositions for the sublingual delivery of opioids. The invention also provides delivery devices adapted for sublingual delivery of such compositions.
US20110274740 METHODS OF REDUCING SYMPTOMS IN SUBJECTS USING SINGLE DOSAGE FORMS WITH TAPERING RELEASE RATES  
The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering...
US20110237615 Narcotic Drug Formulations with Decreased Abuse Potential  
The present application relates to novel narcotic formulations having a decreased injection abuse potential In a representative embodiment, the formulation comprises methadone hydrochloride...
US20140179796 MARKERS FOR DCIS RECURRENCE: COORDINATE PTEN/RB LOSS  
The technology described herein relates to compositions, kits, assays, systems and methods relating to breast cancer and the treatment thereof.
US20130171256 ALCOHOL-RESISTANT EXTENDED RELEASE DOSAGE FORMS COMPRISING VENLAFAXINE  
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing venlafaxine or a pharmaceutically...
US20150167100 Hereditary Cancer Genes  
The disclosure generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
US20140296198 Assay For Predictive Biomarkers Of Anti-Estrogen Efficacy  
Biomarkers associated with anti-estrogen sensitivity in cancers, methods for detecting and quantitating the biomarkers, and methods for treating cancer patients that exhibit the biomarkers are...
US20140315844 MULTI-GENE SIGNATURES FOR PREDICTING RESPONSE TO CHEMOTHERAPY OR RISK OF METASTASIS FOR BREAST CANCER  
Exemplary embodiments of the invention provide methods and compositions relating to a multi-gene signature, and subsets thereof, for predicting whether an individual with breast cancer will...
US20130072475 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ASTHMA AND ASSOCIATED DISORDERS  
This disclosure provides methods for treating asthma or an associated disorder in a patient in need thereof, by administering to the patient an effective amount of an autophagy inducing agent,...
US20110160186 Methods of Treating CYP2D6 Alternative Metabolizers  
The invention provides various methods comprising the administration of a CYP2D6 bioactive drug covalently bound to a water-soluble oligomer. Metabolism of CYP2D6 bioactive drug conjugates is...
US20110008465 SESQUITERPENE FORMULATIONS, KITS AND METHODS OF USE THEREOF  
A pharmaceutical composition comprising a water insoluble sesquiterpene, one or more antioxidants and one or more solubilizers selected from the group consisting of an oil, PEG400, a derivative of...
US20120093938 ORALLY DISINTEGRATING TABLETS COMPRISING DIPHENHYDRAMINE  
The compositions of the present invention comprise a therapeutically effective amount of particles consisting of diphenhydramine or pharmaceutically acceptable salts thereof, optionally in...
US20130190237 METHODS FOR CATEGORISING CANCER SUCH AS BREAST CANCER  
A method for aiding in categorising or determining prognosis in a patient with cancer, for example breast cancer (or, for example, hepatocellular, bladder or gastric cancer) or in selecting a...
US20110008333 METHODS OF INHIBITING UNWANTED CELL PROLIFERATION USING HEDGEHOG ANTAGONISTS  
The present application is directed to compositions and methods for inhibiting angiogenesis and treating or preventing unwanted cell proliferation, including tumors, by inhibiting the hedgehog...
US20110318411 MULTI-LAYERED ORALLY DISINTEGRATING TABLET AND THE MANUFACTURE THEREOF  
The present invention features a tablet containing a first layer and a second layer, wherein: (i) the first layer includes a pharmaceutically active agent and the composition of the first layer is...
US20130296438 METHODS AND COMPOSITIONS FOR USE WITH K-RAS MEDIATED DISORDERS  
Methods and compositions that can be used to identify and characterize inhibitors of K-ras localization to the plasma membrane and in doing so inhibit the signal transduction of K-ras. Such...
US20110165234 EXTENDED RELEASE VENLAFAXINE FORMULATION  
A controlled release dosage form of venlafaxine that comprises an immediate release pellet and an extended release pellet.
US20100190705 Suppression of glial fibrillary acidic protein  
Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell....
US20140072571 OSTEOPOROSIS ASSOCIATED MARKERS AND METHODS OF USE  
Disclosed are methods of identifying subjects with osteoporosis or osteopenia, subjects at risk for developing osteoporosis, osteopenia, and bone fractures, methods of evaluating the effectiveness...

Matches 1 - 50 out of 279 1 2 3 4 5 6 >