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US20090312430 |
COLCHICINE SOLID-STATE FORMS; METHODS OF MAKING; AND METHODS OF USE THEREOF
Disclosed are new colchicine solid-state forms, methods of preparing the solid-state forms, as well as formulations prepared therefrom and uses thereof.
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US20090304663 |
USE OF GSK-3 INHIBITORS FOR THE TREATMENT OF PROSTATE CANCER
A method of combating prostate cancer in a mammalian individual, the method comprising administering an inhibitor of glycogen synthase kinase-3 (GSK-3), or a polynucleotide which encodes an...
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US20090306215 |
DEUTERIUM-ENRICHED ARFORMOTEROL
The present application describes deuterium-enriched arformoterol, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
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US20090291020 |
SOFT CONTACT LENS SOLUTION CONTAINING HYALURONIC ACID
A contact lens kit may include one or more soft contact lenses stored in an ophthalmologically acceptable solution of hyaluronic acid or a salt of hyaluronic acid. A method of disinfecting a soft...
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US20090285881 |
CATIONIC LIPIDS AND USES THEREOF
Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
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US20090263435 |
COMPOSITIONS AND METHODS FOR MINIMIZING AND/OR REDUCING THE APPEARANCE OF DEFECTS AROUND EYES
The invention relates to compositions comprising at least one xanthine compound, preferably further comprising at least one agent which acts on capillary circulation and/or at least one natural...
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US20090247640 |
ANTIMICROBIALS HAVING POLYQUATERNARY AMMONIUMS AND ALCOHOL-BEARING AMIDOAMINES AND METHODS FOR THEIR USE
Antimicrobial or preservative compositions with high user comfort and/or low ocular irritation. The compositions comprise a polyquaternary ammonium compound and an amidoamine having an alcohol...
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US20090239951 |
Crystalline Material
The invention relates to novel crystalline forms of 3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)-phenoxy]-phen
yl]-amino]-3-oxopropanoic acid, said crystalline forms being characterised by a...
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US20090221596 |
Substtituted aryl oximes
The invention relates to compounds of the formula (I)
in which
A 1 , A 2 , R 1 , R 2 , R 3 , R 4 , R 5 and X are as defined in the description,
to processes and intermediates for their...
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US20090220616 |
MOISTURIZING AND LUBRICATING COMPOSITIONS
The present invention is generally directed to moisturizing and lubricating compositions for use on the bodyfacing surface of an absorbent product or on one or both faces of a tissue product. The...
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US20090203651 |
USE OF SPHINGOLIPIDS IN THE TREATMENT AND PREVENTION OF TYPE 2 DIABETES MELLITUS, INSULIN RESISTANCE AND METABOLIC SYNDROME
The present invention relates to the use of sphingolipids for the preparation of a food item, a food supplement and/or a medicament for the treatment and/or prevention of insulin resistance,...
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US20090197966 |
Use of Hypothermia Inducing Drugs
The present invention relates to the induction of hypothermia in humans in a predictable and dose responsive fashion by use of a pharmaceutical composition comprising a vanilloid receptor agonists,...
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US20090192192 |
INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA
The present invention relates to the use of compounds as broad spectrum inhibitors of bacterial biofilm formation. In particular the invention refers to a family of compounds that block the quorum...
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US20090191136 |
USE OF ACTIVE SUBSTANCE COMPLEXES OF PANTHENOL, GLYCEROL, CITRATE AND/OR BISABOLOL AGAINST POLLEN ALLERGIES
A cosmetic or dermatological preparation for combating or substantially preventing pollen allergies. The preparation comprises panthenol, glycerol and at least one of citrate and bisabolol and has...
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US20090182014 |
INSECTICIDAL COMPOSITIONS COMPRISING COMPOUNDS HAVING INHIBITORY ACTIVITY VERSUS ACYL COA: CHOLESTEROL ACYLTRANSFERASE OR SALTS THEREOF AS EFFECTIVE INGREDIENTS
The present invention relates to insecticidal compositions comprising compounds having an inhibitory activity versus acyl CoA: cholesterol acyltransferase (ACAT) or salts thereof as effective...
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US20090182048 |
Compounds Useful For Treating Neurological Disorders
The invention relates to the use of compounds for the preparation of a medicament for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. The invention...
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US20090155186 |
Compositions and methods for treating inflammatory conditions
The present invention relates to compositions containing signal transduction modulator compounds, to methods for treating or preventing inflammation, or promoting healthy joints, using the...
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US20090124699 |
Silicone Material for Releasing an Active Molecule
The invention concerns a material, preferably adhesive, for releasing an active molecule for cosmetic use or personal care or a pharmaceutically or biologically active molecule for pharmaceutical...
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US20090118215 |
Bioresorbable Controlled-Release Composition
A novel method for the preparation of a highly densified and at least partly, preferably fully or almost fully hydrated ceramic for use in the preparation of a pharmaceutical composition notably...
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US20090117207 |
Methods and compositions for treatment of poison-caused pathology
A method of treating a poison-caused pathology in an individual subject is described which includes administering a pharmaceutical composition including a therapeutically effective amount of a...
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US20090093669 |
MAGNETOPHORESIS APPARATUS AND METHOD OF USE
A method and apparatus for administering drugs through a dermal or mucosal layer such that the treatment device may be applied to the mammal for the transdermal or transmucosal administration of...
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US20090082464 |
EXTERNALLY MASKED NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
Masked nitrogen-substituted and oxygen-substituted neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and...
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US20090069419 |
MASKED CARBOXYLATE NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
Masked carboxylate neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating...
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US20090062285 |
SULFUR-CONTAINING COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF
The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide...
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US20090054526 |
INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS
Compounds, pharmaceuticals, cosmetic or dietary supplements for the treatment of overweight, obesity and/or type II diabetes in a mammal (e.g. human) comprising a compound with formula I or formula...
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US20090053319 |
Sore Throat Relief Composition And Method of Producing Same
The present invention provides a sore throat relief composition and a method of producing the composition comprising oleoresin capsicum containing capsaicin, dihydrocapsaicin,...
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US20090042993 |
IDENTIFICATION OF NOVEL POST-TRANSLATIONAL PROTEIN MODIFICATIONS
Compositions and methods for post-translational modifications that include protein acetylation in the ER lumen and deacetylation in the Golgi apparatus are provided. The disclosed methods are...
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US20090041874 |
Karaya Gum-Based Hydrophilic Gel System for Skin Care
A hydrophile gel system for cosmetic and/or skin care applications. The gel system comprises a detachable carrier film and a hydrogel which contains at least 15 percent by weight of karaya gum and...
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US20090022780 |
HYDROGEL
The invention is related to gel preparations capable of absorbing as well as releasing liquid, and the use of such gel preparations in the treatment of wounds.
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US20080319015 |
Insect Repellent Mixture
The present invention relates to the use of an insect repellent, preferably selected from the group 2-(2-hydroxyethyl)-1-methylpropyl 1-piperidinecarboxylate, N,N-diethyl-3-methylbenzamide,...
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US20080317815 |
Induction of a physiological dispersion response in bacterial cells in a biofilm
One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising:
H 3 C—(CH...
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US20080312317 |
12 MEMBERED-RING MACROLACTAM DERIVATIVES
There provided a 12-membered-ring macrolactam derivative having antitumor activity: A compound represented by Formula (1) or a salt thereof. In this Formula, R 1 is a hydrogen atom, a C 1-6 alkyl...
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US20080300205 |
Epigenetic mechanisms re-establish access to long-term memory after neuronal loss
The invention relates to methods and products for enhancing and improving recovery of lost memories. In particular the methods are accomplished through the increase of histone acetylation.
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US20080293676 |
Insecticidal Agents Based on Selected Insecticides and Safeners
Insecticidal compositions characterized by an effective amount of an active ingredient combination comprising
(a) one or more compounds selected from the group of acetylcholinesterase inhibitors,...
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US20080286205 |
Method for Treating Prostate Diseases Based on Local Delivery of Active Substances
A method for treating prostate related diseases in a subject, the method comprising i) optionally administering to subject an initial boost dose of one or more active substances and/or prodrugs,...
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US20080287407 |
Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use
The invention describes novel nitrosated and/or nitrosylated pyruvate compounds and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or...
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US20080274159 |
DRUG FORMULATIONS FOR COATING MEDICAL DEVICES
The present invention relates to oil-based formulations of hydrophobic drugs for the uniform coating of medical devices such as vascular stents and balloons. Another aspect of the present invention...
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US20080268077 |
Process for Strengthening the Barrier Function of Undamaged Skin
A process is described for strengthening the barrier function of undamaged skin in particular against allergens and/or for preventing or inhibiting an allergic reaction of undamaged skin on contact...
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US20080255127 |
Pesticide Formulations with a Crystallization Risk, and a Method for Their Preparation
Pesticide formulations with a crystallization risk are provided. Also provided are methods of making and using such formulations.
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US20080234204 |
Methods for evaluating and implementing prostate disease treatments
Provide is a method for evaluating test agents as candidates for treating prostatic diseases, including benign prostatic hyperplasia (BPH) and androgen dependent and androgen independent prostate...
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US20080227635 |
Dicyano Alkanoic Acid Amides for Combating Animal Pests
Dicyano alkanoic acid amides of formula (I), wherein R 1 is H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, or haloalkynyl; R 2 is H, CN, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl,...
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US20080214506 |
Novel use of ion channel active compound, meperidine, to mediate process of accelerated wound healing
The present invention discloses a method of employing ion channel active compounds to delivery metabolism-enhancing molecules within the cell to promote rapid wound healing. It also develops a...
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US20080202967 |
Cosmetic Product
This invention relates to a treatment pad which may be used in cosmetic treatment and which produces soothing, relaxing, calming and similar effects in persons. The treatment pad comprises 0.1 to...
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US20080207753 |
Analogues of lipid mediators derived from omega-3 PUFAs and methods of use
The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ω-3; EPA], but with a longer tissue...
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US20080177108 |
Phenyloxyaniline derivatives
The present invention relates to phenyloxyaniline derivatives, to methods of their production and to uses thereof.
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US20080171783 |
COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE
The present disclosure provides amide-based, non-nucleoside compounds having an inhibitory activity against endogenous polymerases, such as polymerase alpha and polymerase gamma. This disclosure...
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US20080166378 |
DEATH RECEPTOR SENSITIZING COMPOUNDS AND METHODS OF USE THEREFOR
Methods of identifying death receptor sensitizing compounds and methods of using death receptor sensitizing compounds are provided.
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US20080161379 |
Methods of Treating Diabetes Mellitus
The invention provides methods of treating a diabetic subject comprising administering a glucosylceramide synthase inhibitor to the subject.
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US20080146548 |
AMIDE, ARYL SULFONAMIDE, ARYL UREA, AND a,b-DIKETONE DERIVED CARBOXYLESTERASE INHIBITORS, AND THEIR METHODS OF USE
This disclosure relates to amides, aryl sulphonamides, aryl ureas, and α,β-diketones derivatives useful as carboxylesterase esterase inhibitors. The disclosure is also directed to the use of...
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US20080146527 |
ANTIBACTERIAL 1-(4-MONO- AND DI-HALOMETHYLSULPHONYLPHENYL)-2-ACYLAMINO-3-FLUOROPROPONALS AND PREPARATION THEREOF
Novel florfenicol compounds having the chemical structure:
or a pharmaceutically-acceptable salt thereof or a solvate thereof, or prodrug thereof, wherein R 1 is CHCl 2 , CHClF, CHF 2 ,...
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