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US20090286862 |
Therapeutic agent for psychoneurotic disease
The present invention relates to a preventive and/or therapeutic agent for psychoneurotic diseases, comprising an EP 3 antagonist represented by the general formula (I):
(wherein the meanings...
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US20090286781 |
Use of Suluble Guanylate Cyclase Acitvators for Treating Acute and Chronic Lung Diseases
The present invention relates to the use of compounds of the formulae I-VI for manufacturing a pharmaceutical for the treatment of acute and chronic lung disorders such as the respiratory distress...
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US20090286760 |
Novel Compositions and Methods for Treating Hyperproliferative Diseases
The invention relates to a composition that includes a first agent selected including an agent that possesses anti-inflammatory activity or acetaminophen, phenacetin, tramadol and the like; a...
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US20090281093 |
ANTI-INFLAMMATORY COMPOUNDS
The present invention relates to novel non steroidal anti-inflammatory compounds (NSAIDs) that release hydrogen sulfide (H 2 S). The present invention also provides methods for treating, preventing...
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US20090280112 |
INHIBITORY EFFECTS OF NORDIHYDROGUAIARETIC ACID (NDGA) ON THE IGF-1 RECEPTOR AND ANDROGEN DEPENDENT GROWTH OF LAPC-4 PROSTATE CANCER CELLS
Disclosed herein are methods and compositions for the treatment of prostate cancer with an IGF-1 receptor kinase inhibitor. Methods are also provided for the treatment of prostate cancer by...
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US20090275626 |
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEUROGENIC PAIN
The purpose of the present invention is to provide agents useful for the prevention or treatment of a neuropathic pain. That is, the present invention provides agents for the prevention or...
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US20090270507 |
Concentrated Liquid Thyroid Hormone Composition
This invention is directed generally to a liquid pharmaceutical composition comprising at least one thyroid hormone (particularly a composition further comprising at least one cyclodextrin...
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US20090270506 |
CRYSTALLINE STRUCTURE OF OXIDOSQUALENE SYNTHASE
The present invention relates to crystal forms of mammalian OSC and the crystal structure information obtained from them, to methods of preparing such crystal forms, and to their use for the...
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US20090264469 |
NOVEL DICARBOXYLIC ACID DERIVATIVES
The present patent application concerns new compounds of formula (I): displaying agonistic activity at sphingosine-1-phosphate (S1P) receptors, their process of preparation and their use as...
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US20090252716 |
METHODS FOR IDENTIFYING NUCLEAR RECEPTOR/LIGAND COMBINATIONS FOR TARGETING BRAIN TUMOR STEM CELLS AND FOR THEIR USE
An in vitro method is provided for identifying nuclear receptors abnormally expressed by brain tumor stem cells and a corresponding ligand which, if administered to brain tumor stem cells (BTSC's),...
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US20090247638 |
PHARMACEUTICAL USE OF COX-2-INHIBITORS IN ANGIOGENESIS-MEDIATED OCULAR DISORDERS
The invention provides a method of treating an angiogenesis-mediated ocular disorder, e.g. ocular neovascularisation, retinal neovascularisation, including neovascularisation following injury or...
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US20090246233 |
Treatment of Gastroparesis and Nonulcer Dyspepsia With GABAB Agonists
The present invention relates to formulations comprising a therapeutically effective amount of baclofen or (R)-baclofen, or pharmaceutically acceptable salts thereof, and methods of their use. The...
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US20090238846 |
S/O type external preparation
The present invention provides an external preparation which can improve a skin permeability of a hydrophilic medicine such as NSAID so that the medicine can act directly on a diseased area without...
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US20090234012 |
ADMINISTRATION OF DOPA PRECURSORS WITH SOURCES OF DOPA TO EFFECTUATE OPTIMAL CATECHOLAMINE NEUROTRANSMITTER OUTCOMES
A method of treating neurotransmitter dysfunction in a patient by optimizing catecholamine levels by administration of L-3,4-dihydroxyphenylalanine (L-Dopa or Dopa) precursors in combination with a...
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US20090233970 |
COMBINED NSAID AND ACID BLOCKER FORMULATION AND METHOD
The present invention is directed to co-administration of a non-steroidal anti-inflammatory agent (NSAID) and acid blocking agent for the treatment of pain and inflammation with reduced...
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US20090233962 |
Amide derivative and insecticide containing the same
The present invention is to provide a compound represented by the general formula (1) exhibiting a high insecticidal effect and an insecticide comprising the compound as an active ingredient. The...
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US20090232754 |
ENHANCED PHOTOSTABILITY OF SUNCARE COMPOSITIONS CONTAINING AVOBENZONE
The photostability of avobenzone in a sunscreen composition is stabilized against photodegradation using menthyl anthranilate.
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US20090227680 |
Amino Acid Derivatives
The present invention relates to a method of treating pain using a compound of formula (I), wherein Ar, R 1 , R 3 and R 3a are as defined herein. The invention also relates to certain novel...
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US20090227673 |
Method and Composition for the Treatment of Parkinson's Disease
It has been discovered that polyphenols are effective as a co-pharmaceutical in combination with traditional dual drug therapies of catecholamines and decarboxylase inhibitors for the treatment of...
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US20090226507 |
HYDROXIDE-RELEASING AGENTS AS SKIN PERMEATION ENHANCERS
A method is provided for increasing the permeability of skin or mucosal tissue to topically or transdermally administered pharmacologically or cosmeceutically active agents. The method involves use...
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US20090221707 |
Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained
The present invention relates to a process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, its components...
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US20090221573 |
Use of Activators of Soluble Guanylate Cyclase for Promoting Wound Healing
The present invention relates to a method for promoting wound healing by administering one or more compounds identified in the claims, and to pharmaceutical compositions containing such compounds.
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US20090221552 |
Methods for the Treatment of ADHD and Related Disorders
The invention features methods, compositions, and kits for the treatment of attention deficit hyperactivity disorder and related behavioral disorders by administering an organic cation 3 (hOCT3)...
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US20090215819 |
ANTI-INFECTIVE AND IMMUNOMODULATORY COMPOUNDS
The present invention provides pharmaceutical compositions and methods that include the use of anti-infective compounds that potentiate the host-immune response or limit or prevent the expression...
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US20090215769 |
Use of soluble guanylate cyclase activators for the treatment of Raynaud's Phenomenon
The present invention relates to a method for prevention or treatment of primary and secondary Raynaud's phenomenon comprising administration of an effective amount of a compound selected from...
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US20090214680 |
Weight Loss Composition
The present invention comprises a purposefully formulated weight loss composition and a method for causing a meaningful weight loss in a living human subject. The formulated weight loss...
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US20090214650 |
Methods of Treating alcoholism and alcohol related disorders using combination drug therapy and swellable polymers
The current invention provides methods of treating alcohol related disorders by providing a sustained release oral drug dosage form comprising a plurality of solid state drugs i.e., baclofen and...
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US20090214644 |
TRANEXAMIC ACID FORMULATIONS WITH REDUCED ADVERSE EFFECTS
Disclosed are delayed release oral tranexamic acid formulations and methods of treatment therewith.
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US20090209558 |
Polymer formulations for delivery of bioactive materials
Delivery of drugs in association with PLGA polymers which have crystallinity resulting from the presence of long chain alkyl groups in terminal units.
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US20090208558 |
Use of Combination Preparations Comprising Antifungal Agents
The invention relates to the use of an antimycotic agent and an epithelial cell or endothelial cell adhesion inhibitor for producing a combination drug for the topical treatment of Candida ...
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US20090208554 |
Baclofen Formulation in a Polyorthoester Carrier
Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an...
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US20090203789 |
Fast Dissolution Amino Acid Composition
The present invention relates to oral dosage formulations for the rapid release of amino acids. A rapid release is achieved through the process of milling whereby the milled amino acids are more...
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US20090203720 |
Methods for inhibiting cell growth
Cell growth is inhibited and/or cell death is induced in a cell by administering an RXR agonist and an inhibitor of casein kinase 1α. A cell or a tissue can be screened for enhanced susceptibility...
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US20090203669 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ADDICTION AND OTHER NEUROPSYCHIATRIC DISORDERS
The present invention is based, in part, on our discovery that certain types of therapeutic agents can be used in combination to treat a variety of neuropsychiatric and related disorders, including...
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US20090203654 |
COSMETIC AND PHARMACEUTICAL COMPOSITIONS
This invention relates to novel compounds that display retinoid like activities, including HB-EGF (Heparin Binding Epidermal Growth Factor) release from keratinocytes, cell proliferation, and...
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US20090197960 |
Method of Inhibiting Polyneuropathic Pain with 3-(2-Dimethylaminomethylcyclohexyl) Phenol
A method of using 3-(2-dimethylaminomethylcyclohexyl)phenol or a pharmaceutically acceptable salt thereof as an active pharmaceutical ingredient for treating or inhibiting polyneuropathic pain, in...
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US20090197958 |
Sustained Release Particulate Oral Dosage Forms of (R) Baclofen and Methods of Treatment
Sustained release particulate oral dosage forms of (R)-baclofen prodrugs and methods of treating a disease comprising orally administering such dosage forms are disclosed.
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US20090191152 |
INTRALYMPHATIC CHEMOTHERAPY DRUG CARRIERS
A chemotherapeutic composition can be configured for subcutaneous administration for preferential intralymphatic accumulation while also providing a therapeutic systemic concentration that is not...
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US20090186935 |
TASTE TITRATION THERAPIES
The teachings provided herein generally relate to formulations, systems, and methods that have the ability to remit deficiencies and imbalances in a subject's serotonin and dopamine levels. The...
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US20090186034 |
Gene expression markers for inflammatory bowel disease
The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of...
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US20090170948 |
Crystal forms of O-desmethylvenlafaxine fumarate
Provided are crystalline forms of O-desmethylvenlafaxine fumarate, methods for their preparation, and pharmaceutical compositions thereof.
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US20090169533 |
COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES
The present invention relates to compositions and methods for treating neurodegenerative diseases. In some embodiments, the present invention provides compositions for treating and preventing...
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US20090155369 |
PHARMACEUTICAL COMPOSITION CONTAINING LEVODOPA, ENTACAPONE AND CARBIDOPA
The present invention refers to a solid pharmaceutical composition of entacapone, levodopa and carbidopa or pharmaceutically acceptable salts thereof characterized in that entacapone is in the form...
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US20090155235 |
AGGREGATES WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN
The invention describes combinations of at least three amphipatic substances forming aggregate suspensions in a polar liquid. Judicious choice of system components, which differ at least 2-times to...
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US20090149543 |
SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING LUMIRACOXIB
A method of treating a cyclooxygenase-2 dependent disorder or condition comprising administering 5-methyl-2-(2′-chloro-6′-fluoroanilino)phenylacetic acid in an amount effective to treat such a...
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US20090149542 |
COMPOUNDS AND COMPOSITIONS FOR TREATING NEURONAL DEATH OR NEUROLOGICAL DYSFUNCTION
The present invention relates to 2-hydroxy-alkylamino-benzoic acid derivatives and to a combination of cell necrosis inhibitor and lithium, process for the preparation of the derivatives or the...
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US20090143762 |
Methods and Compositions for Enhancing the Viability Of Microneedle Pores
Described herein is a method of transdermally administering one or more pharmaceutically active agents to a mammal. The method comprises administering one or more active pharmaceutical agents to...
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US20090137543 |
METHOD AND COMPOUNDS FOR MODULATING INSULIN PRODUCTION
The present invention provides screening methods for the detection of agents that affect various aspects of β-cell biology, particularly insulin gene expression. Screening methods are also...
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US20090131527 |
NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME
The present invention relates to novel anthranilic acid derivatives represented by Chemical Formula I, and a chloride channel blocking agent containing the anthranilic acid derivative or its...
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US20090130202 |
Pharmaceutical Compositions
Sustained release pharmaceutical compositions contain a drug; microcrystalline cellulose; a diluent (such as starch); a glidant (such as talc); and one or more of ethylcellulose, stearic acid and a...
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