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US20090275659 |
Phenyl acetic acid derivatives as inflammation modulators
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides...
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US20090274632 |
Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in composition and use thereof
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the...
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US20090258844 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISORDERS OF THE CENTRAL AND PERIPHERAL NERVOUS SYSTEMS
The present invention relates to methods and compositions for treating selected conditions of the central and peripheral nervous systems employing non-synaptic mechanisms. More specifically, one...
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US20090258030 |
Materials and Methods for Improving Livestock Productivity
The subject invention provides methods for improving livestock health. In specific embodiments, the invention provides methods for accelerating and/or augmenting livestock growth; improving...
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US20090253793 |
COMPOSITION AND METHOD FOR BINDING ACETALDEHYDE IN STOMACH
This invention relates to a non-toxic composition which bind acetaldehyde present in the stomach, intestine and/or colon. The composition comprises one or more acetaldehyde-binding compound(s)...
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US20090247479 |
Therapeutic Use of Methionine to Reduce the Toxicity of Aminoglycoside Antibiotics
Methods of preventing or reducing ototoxicity in patients undergoing treatment with therapeutically effective amounts of aminoglycoside antibiotics are provided. The methods comprise administering...
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US20090233995 |
Use of drug combinations for treating insulin resistance
The present invention provides pharmaceutical compositions comprising: (a) a modulator of hepatic parasympathetic tone, (b) at least one diabetes drug, and (c) a pharmaceutically acceptable...
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US20090220450 |
Methods and compositions for wound healing
Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of wound healing and/or tissue repair.
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US20090209647 |
NUTRITIONAL METHOD
A method of improving nutrition and/or treating low grade inflammation in an elderly human subject comprises administering to said subject a cysteine source so as to provide metabolically available...
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US20090209480 |
CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS
The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous...
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US20090203626 |
Pediatric Amino Acid Solution for Parenteral Nutrition
The present invention relates to an amino acid solution for the parenteral nutrition of pediatric patients. The amino acid solution provides for an increased concentration of glutamine, tyrosine,...
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US20090192227 |
N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease
The present invention relates to N-acetylcysteine compositions and methods for treating inflammation and redox imbalance in acute exacerbations of inflammatory lung disease.
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US20090192125 |
Local anti-infective agent for treatment of nail fungal infections
A topical composition for treating nail fungal infections that utilizes an acidic antifungal agent with a molecular weight no greater than 170 Daltons in a formulation having a pH less than or...
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US20090181910 |
METHOD OF PREVENTION AND ALLEVIATION OF TOXICITY BY MODULATION OF IRF3
The invention provides compounds, compositions, animal models, drug screening methods, pharmaceutical compositions, and methods of treatment which relate to the modulation of the metabolism of...
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US20090181901 |
COMPOSITIONS AND METHODS TO INCREASE BIOAVAILABILITY OF CAROTENOIDS
The present invention relates to compositions and methods of use to increase the bioavailability of a carotenoid in a subject. The compositions include a carotenoid and either an anthocyanin or a...
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US20090176743 |
Methods for treating or preventing reactivation of a latent herpesvirus infection
The invention is directed to methods and compositions for treating or preventing reactivation of a latent herpesvirus infection and the associated complications and outcomes. The methods involve...
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US20090169497 |
Treatment and Prevention of Skin Injury Due to Exposure to Ultraviolet Light
Photoprotective agents useful for the treatment or prevention of cell damage, particularly skin injury due to UV-light. Methods of prevention or treatment of cell damage and skin injury due to...
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US20090163547 |
INDENE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS
The present invention makes reference to new indene derivatives with general formula (I), as well as to their preparation procedures, their application as medicament and the pharmaceutical...
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US20090163487 |
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS
The invention relates to N-hydroxylsulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of...
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US20090156581 |
Aminergic pharmaceutical compositions and methods
Pharmaceutical compositions and method using aminergic compounds and complement compounds. Compositions are provided comprising: (a) a subefficacious amount of a non-adrenergic aminergic compound...
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US20090155186 |
Compositions and methods for treating inflammatory conditions
The present invention relates to compositions containing signal transduction modulator compounds, to methods for treating or preventing inflammation, or promoting healthy joints, using the...
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US20090149540 |
Compositions and Methods for Attenuating Mitochondria-Mediated Cell Injury
The present invention relates to a S-nitrosated mitochondria-targeted thiol-based antioxidant prodrug and uses therefore for the prevention or treatment of diseases or conditions associated with...
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US20090149428 |
Methods for Assessing the Predisposition or Susceptibility to COPD
This invention relates to novel associations between polymorphisms in the genes encoding the human Epithelial Na+ Channel (ENaC) and COPD. More particularly, the invention relates to a method for...
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US20090149397 |
TREATMENT OF CANCER WITH COMBINATIONS OF TOPOISOMERASE INHIBITORS AND PARP INHIBITORS
In one aspect, the present invention provides a composition and a kit comprising a combination of topoisomerase inhibitor and PARP inhibitor for treatment of cancer. In another aspect, the...
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US20090142420 |
Cosmetic Composition with Anti-Free Radical Activity
A cosmetic composition has an association of at least three of the following substances with anti-free radical activity, selected from: A cosmetic composition has an association of at least three...
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US20090123446 |
Use of IL-1 Antagonists to Treat Gout
Methods of treating, inhibiting, or ameliorating gout, including chronic acute (refractory) gout, pseudogout, or drug-induced gout, in a human subject in need thereof, comprising administering to a...
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US20090105218 |
CRTH2 Receptor Ligands For Therapeutic Use
Compounds of formula (I) are useful in the treatment of disease responsive to modulation of CRTH2 receptor activity, wherein: A represents a carboxyl group —COOH, or a carboxyl bioisostere; L1 is...
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US20090081279 |
Skin Dressings
A skin dressing is adapted, on activation, to release one or more S-nitrosothiols, preferably S-nitroso-L-glutathione. S-nitrosothiols decompose spontaneously to produce nitric oxide, which has...
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US20090081177 |
Methods and compositions for improving pregnancy outcome
A method of increasing pregnancy rate in a female subject is provided, the female subject or an oocyte for introduction into the female subject being fertilized by a sperm from a male subject. The...
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US20090076111 |
Methods for improving glycemic control in humans
The present invention is directed to methods for improving glycemic control in humans and animals comprising the step of administering a composition comprising an amino acid content including...
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US20090060922 |
Acetamide Stereoisomer
The compound of formula (I)
is a water-stable, long acting β 2 -selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible...
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US20090048342 |
Combination of Bioavailable Methionine With at Least One Essential Oil
The invention concerns a food composition, designed to complement animal feed in methionine, said composition having a synergistic bactericidal effect on the bacterial activity of the bowel flora....
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US20090041681 |
Anti-inflammatory inhalation pharmaceutical composition
The present invention is directed to the discovery of the anti-inflammatory properties of basic amino salts of acetylcysteine when administered directly to the lungs and/or the nose. This observed...
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US20090036534 |
Method Of Synthesizing S-Allyl-Cysteine Analogues And Their Therapeutic Application In Treating Myocardial Infarction
A pharmaceutical composition and methods of producing and application of the composition for treating myocardial infarction of a subject are disclosed. The pharmaceutical composition comprises a...
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US20090036462 |
Formulations for parenteral administration of (e)-2, 6-dialkoxystyryl 4-substituted benzylsulfones
Formulations are provided for parenteral administration of (amino substituted (e)-2,6-dialkoxystyryl 4-substituted benzylsulfones and the sodium and potassium salts thereof for the prevention...
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US20090036356 |
Octanoic acid derivatives as dipeptidyl peptidase inhibitors
The present invention is directed to novel Octanoic acid derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or...
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US20090030079 |
USES OF TRIENTINE AND PENICILLAMINE AS COUNTERMEASURES TO METAL CONTAMINATION
Methods are provided for the alleviation, prevention and treatment of negative effects of overexposure to metal contaminants. Subjects exposed to a metal contaminant can be treated using trientine...
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US20090029949 |
GPCR Ligands Identified by Computational Modeling
Disclosed are pharmacophores for developing and screening compounds having G-protein-coupled receptor antagonist activity, including LPA 1 , LPA 2 , LPA 3 and S1P antagonists. These compositions...
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US20090029903 |
1,1'-(1,2-Ethynediyl)Bis-Benzene Derivatives As Ptp 1-B Inhibitors
The present invention is related to carboxylic acids of Formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or...
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US20090022813 |
COMPOSITION FOR IMPROVING MEMBRANE COMPOSITION AND FUNCTIONING OF CELLS
It has now been found that after administration to a diseased person or person that is at risk for developing such disease of a neutraceutical or pharmaceutical composition that comprises
a)...
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US20090012142 |
Compositions and Methods for Increasing Lean Muscle Mass and/or Reducing Fat Gain
Compositions and methods for increasing lean muscle mass and/or reducing fat gain in growing animals by feeding the animals a composition having a total lysine to metabolizable energy ratio of from...
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US20090011986 |
Thiosuccinic Acid Derivatives and the Use Thereof
The present invention relates to compounds of the Formula (I), wherein X 1 and X 2 independently represent O, NH or S; R 1 and R 2 are independently selected from the group consisting of a...
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US20080319072 |
COMPOSITION AND METHOD FOR TREATING BACTERIAL, VIRAL, FUNGAL DISEASES, INFLAMMATION AND PAIN
The present invention is directed to compositions and methods of treating bacterial, viral, fungal diseases; inflammation or inflammatory-related disorders; pain; and skin conditions. The...
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US20080317856 |
Compositions Containing A Capillary -Active System With Application -Relevant Differentiability, And The Use Thereof
This invention relates to compositions with a capillary-active system with application-relevant differentiability and synergistic potential for use in mammals, especially humans. The invention...
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US20080317835 |
Personalized Nutrient Deficiency Assay Methods
Assays are preformed to determine nutrient deficiency levels in an individual to address the deficiencies and improve health and longevity. Nutraceutical and cosmeceutical products containing...
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US20080312326 |
Method for the Prevention and/or Treatment of Neurodegenerative Diseases Characterized by Administering and Ep1 Receptor Antagonist
The present invention relates to the use of EP 1 receptor antagonists for the treatment of neurodegenerative diseases, for example, Alzheimer's disease, Parkinson's disease, Parkinson syndrome,...
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US20080306158 |
Methods to Prevent Cytotoxicity Using N-Acetyl-Cysteine
Compositions and methods to inhibit adverse physiological effects caused by resin-based and resin-containing materials are disclosed. More specifically, the use of N-acetyl-cysteine (NAC) to...
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US20080305094 |
Nutritional Composition for Improving Skin Condition and Preventing Skin Diseases
The present invention pertains to the use of an ingestable composition containing L-carnitine and at least one component having an anti-oxidative activity for stimulating the lipid metabolism in...
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US20080287541 |
Kit for Treatment of Cancer
The present invention relates to a kit for the treatment of cancer comprising (a) a container for containing a first compound (i) or a precursor thereof, said first compound or precursor being a...
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US20080287477 |
Novel Compounds as Modulators of Ppar
Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
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