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US20130079403 RETINAL DERIVATIVES AND METHODS FOR THE USE THEREOF FOR THE TREATMENT OF VISUAL DISORDERS  
Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
US20110184062 COMPOSITIONS AND METHODS FOR DRY EYE SYNDROME  
Compositions and methods to inhibit dry eye as well as other conditions are provided.
US20150218256 COMPOUNDS FOR TREATING THE REMYELINATION BLOCKADE IN DISEASES ASSOCIATED WITH THE EXPRESSION OF HERV-W ENVELOPE PROTEIN  
The present invention deals with innovative compounds and compositions for preventing and/or treating a newly discovered detrimental mechanism, which blocks the endogenous myelin repair capacity...
US20120196931 Treatment for Multiple Sclerosis  
Provided are certain methods of screening, identifying, and evaluating neuroprotective compounds useful for treatment of neurological diseases, such as, e.g., multiple sclerosis (MS). The...
US20110166224 DIACYLGLYCEROL RICH FATS, OILS AND FUNCTIONAL FOODS  
Disclosed is a fat or oil useful for cooking applications which includes from 10 to 90% by weight diacylglycerols, and has a SFI of at least 15% at room temperature. In particular embodiments, the...
US20110059906 Energy status of an individual by enhanced production of an endogenous fuel source  
The present invention relates to a method of improving the energy status of an individual by enhancing the usage of lactate. Improved lactate usage is accomplished through a composition comprising...
US20130108709 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS  
Pharmaceutical compositions and methods for the treatment of subjects, including humans, who have or are at risk for various disease, disorders and conditions, including, mitochondria-associated...
US20120165404 TREATMENT OF NEURODEGENERATION AND NEUROINFLAMMATION  
Methods of treating a subject having a condition characterized by at least one of neurodegeneration and neuroinflammation are provided. Methods of reducing astrogliosis in a subject having a...
US20140302156 RIGID SHAPED ARTICLE FOR THE TREATMENT OF ITCHING  
The invention concerns a rigid shaped article essentially consisting of a plurality of mutually adhering grains of sand provided with a coating consisting of wax, for the elimination or relief of...
US20130338165 Use of Compounds Elevating Glutathione Levels for the Treatment of Parkinson's Disease  
Methods of treating Parkinson's Disease comprising administering compounds that up-regulate cystine-glutamate exchange (system Xc−) and/or increase glutathione levels in the brain cells. Preferred...
US20120076848 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE  
Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are...
US20140044693 OXIDATIVE RETINAL DISEASES  
Some aspects of the invention provide for a method of treating Wet and/or Dry Age-related Macular Degeneration, Retinitis Pigmentosa, Diabetic Retinopathy, cataracts, and/or Stargardt Disease...
US20140243411 TOPICAL DTPA PRODRUG FORMULATIONS AND METHODS OF USING THE SAME  
The present invention relates to topical trisodium diethylenetriamine pentaacetic acid (DTPA) prodrug formulations and methods of using the same.
US20140142152 METHODS AND COMPOUNDS FOR TREATING CANCER  
The invention includes, in part, methods and compounds for treating cancer including, but not limited to gliomas, melanomas, and neuroblastomas. In some embodiments of the invention, a...
US20120259012 Treatment for Amyotrophic Lateral Sclerosis  
Provided are certain methods of screening, identifying, and evaluating neuroprotective compounds useful for treatment of neurological diseases, such as, e.g., multiple sclerosis (MS). The...
US20110280970 ABSORBABLE PUTTY-LIKE IMPLANTS AND METHODS FOR THEIR USE FOR MECHANICAL HEMOSTASIS OF BONE AND FOR THE TREATMENT OF OSSEOUS DEFECTS  
The present invention relates to mechanically hemostatic body-absorbable compositions having a putty-like consistency comprising a finely powdered, carboxylic acid salt, a liquid block copolymer...
US20140094515 COSMETIC PARTICLES THAT TRANSFORM FROM HARD TO SOFT PARTICLES COMPRISING HYDROGENATED LONG-CHAIN TRIGLYCERIDE OILS  
Cosmetic particle compositions are provided which are adapted to form hard cosmetic particles that transform to soft cosmetic particles after their incorporation into topical formulations,...
US20110301238 SEIZURE RELATED DISORDERS AND THERAPEUTIC METHODS THEREOF  
Methods of treating seizure disorders by administration of a therapeutically effective amount of at least one precursor of propionyl-CoA in the absence of a ketogenic diet are provided. The...
US20100311831 Reduction of Sterols and Other Compounds from Oils  
A process for the removal of sterols, specifically cholesterol, from a triglyceride oil, preferably a marine triglyceride oil, said process comprising contacting an oil with an absorbent,...
US20150133551 Lipids That Increase Insulin Sensitivity And Methods Of Using The Same  
The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including...
US20120095095 USE OF AN OMEGA-3 LIPID-BASED EMULSION FOLLOWING ISCHEMIC INJURY TO PROVIDE PROTECTION AND RECOVERY IN HUMAN ORGANS  
The present invention provides methods of limiting cell death resulting from hypoxic-ischemia comprising, administering an omega-3 lipid-based emulsion after a hypoxic-ischemia insult. The omega-3...
US20110159017 TRYTOPHAN CATABOLISM IN CANCER TREATMENT AND DIAGNOSIS  
The unexpected expression of tryptophan 2,3-dioxygenase (TDO2) in cancer cells and tumors has been established. Methods for diagnosing cancer based on the expression of TDO2 are provided, as are...
US20140163100 Methods of Treating Multiple Sclerosis and Preserving and/or Increasing Myelin Content  
Methods of treating multiple sclerosis in a subject, including: reducing the frequency of relapse, reducing the annualized relapse rate, reducing the risk of disability progression, reducing the...
US20120009285 Compositions for treating skin  
A personal care composition comprising: at least a first phase and a second phase wherein said first phase comprises a) an aqueous structured surfactant phase comprising STnS where n is between...
US20140323570 Neuroprotection in Demyelinating Diseases  
Methods of treating neurological disorders characterized by extensive demyelination and/or axonal loss are provided. Examples of such disorders include secondary progressive multiple sclerosis and...
US20130302410 Neuroprotection in Demyelinating Diseases  
Methods of treating neurological disorders characterized by extensive demyelination and/or axonal loss are provided. Examples of such disorders include secondary progressive multiple sclerosis and...
US20140212464 Composition For Wet Wipes That Enhances The Efficacy of Cleansing While Being Gentle To The Skin  
The present invention describes an oil-in-water emulsion composition for wet-wipes delivering an improved body cleansing performance while providing a gentle and smooth feeling to the user.
US20150246075 METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT  
Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The...
US20140056973 Oral Dosage Forms Having a High Loading of a Methyl Hydrogen Fumarate Prodrug  
Oral dosage forms and granulations with a high loading of a methyl hydrogen fumarate prodrug are disclosed.
US20140288175 GLYCOGEN OR POLYSACCHARIDE STORAGE DISEASE TREATMENT METHOD  
A method for treating glycogen storage disease by administering an effective amount of a composition that includes ketogenic odd carbon fatty acids that ameliorate the symptoms of these diseases.
US20110177061 METHODS OF TREATING AND PREVENTING NEUROLOGICAL DISORDERS USING DOCOSAHEXAENOIC ACID  
The disclosure relates to methods of treating or preventing neurological disorders using docosahexaenoic acid.
US20110201558 Anaplerotic Therapy for Alzheimer's Disease and the Aging Brain  
The present invention describes methods and compositions for the treatment of neurodegenerative conditions including Alzheimer's disease (AD) and aging. The present invention discloses an...
US20120128770 TREATMENT OF INSULIN RESISTANCE AND OBESITY BY STIMULATING GLP-1 RELEASE  
The present invention relates to 1 or 2 C16-C18 acyl glycerol based compounds which are capable of activating G-protein coupled receptor 119 and thereby stimulate GLP-1 release. Compounds of the...
US20130190270 Method for Improving Vein Performance in Bypass Surgery  
Methods to reduce damage to organelles, cells, tissues, organs and organ systems or components thereof caused by strain due to mechanical stress, including stretch stress and shear stress, are...
US20140348915 Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof  
Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also...
US20140348914 Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof  
Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also...
US20140065211 Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof  
Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also...
US20140056978 Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof  
Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also...
US20120277178 COMPOSITIONS AND METHODS FOR TREATING FRAGILE X PREMUTATION RVGG REPEATS-MEDIATED TOXICITY  
Compositions and methods of treatment or prophylaxis of fragile-X associated disorders are provided, as well as methods of screening compounds and kits to screen a library of compounds.
US20130289110 METHODS AND LIPID COMPOSITIONS FOR PROMOTING DEVELOPMENT OF GUT FLORA  
Disclosed is a method of inducing and promoting development of beneficial gut flora in a subject and/or of reducing the frequency and duration of crying periods in a subject, the method comprises...
US20110313039 METHOD FOR INCREASING ENDOGENOUS PLASMALOGEN LEVELS IN MAMMALS  
The present invention relates generally to compounds such as alkylglycerol and alkoxyglycerol for use in increasing the endogenous level of plasmalogens in a mammal. In particular, these compounds...
US20130245116 COMPOSITIONS AND METHODS FOR THE DISRUPTION OF MYCOBACTERIUM BIOFILM  
The present disclosure provides methods and compositions for the disruption of biofilms produced by Mycobacterium. Methods and compositions related to the prevention and treatment of Mycobacterium...
US20110306663 TRIHEPTANOIN DIET FOR ADULT POLYGLUCOSAN BODY DISEASE (APBD) TREATMENT  
Compositions and methods for the treatment and management of adult polyglucosan body disease (APBD) are disclosed herein. The APBD patients studied in the present invention experienced...
US20150183728 COMPOSITIONS AND METHODS FOR THE TREATMENT OF DIABETES AND PRE-DIABETES  
The invention relates to the compositions of formula I or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions...
US20150139935 SLEEP APNEA TREATMENT  
Provided herein is technology relating to treating sleep apnea and particularly, but not exclusively, to treating sleep apnea with immunotherapeutics and/or anti-inflammatory drugs such as...
US20140364498 Anaplerotic Therapy of Huntington Disease and Other Polyglutamine Diseases  
The present invention relates to a method for treating and/or preventing Huntington disease and other polyglutamine diseases, comprising the step of administering an effective amount of a...
US20120165405 Anaplerotic Therapy of Huntington Disease and Other Polyglutamine Diseases  
The present invention relates to a method for treating and/or preventing Huntington disease and other polyglutamine diseases, comprising the step of administering an effective amount of a...
US20120022159 AMPHIPHILIC STAR-LIKE OR SCORPION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF  
Biomedical uses of amphiphilic macromolecules include the use of such macromolecules in the form of nanoparticle formulations for the sequestration and/or removal of LDL, and for the treatment and...
US20110087152 FLUIDIC TISSUE AUGMENTATION COMPOSITIONS AND METHODS  
Compositions and method for augmenting tissue after delivery to localized area. The compositions include a hydrogel and a dermal filler. The hydrogel can polymerize and/or crosslink upon a first...
US20140221482 TRIHEPTANOIN FOR THE TREATMENT OF GLUCOSE TRANSPORT 1 DEFICIENCY  
Provided are methods for treating GLUT1 and related brain energy deficiencies comprising administering odd-carbon fatty acid sources, e.g., C5 or C7 fatty acid sources, and related compositions.