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US20090291109 |
Method and system for dispensing dry bird repellent
Methods and apparatus for dispensing bird repelling chemical solutions, such as a methyl anthranilate (MA) solution in a bird inhalable size, are disclosed. A small particle haze, including a bird...
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US20090264525 |
FLUOROSURFACTANTS
The present invention relates to fatty acid esters of polyols or sulfonated fatty acid esters or sulfonated fatty acid amides containing at least one group Y, where Y stands for CF 3 —(CH 2 ) a...
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US20090264385 |
STABILIZED COMPOSITIONS CONTAINING ALKALINE LABILE DRUGS
A stabilized bioadhesive composition containing an alkaline labile drug and a method for its preparation are provided. In one aspect, the composition is a hot-melt extruded (HME) composition...
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US20090258887 |
Novel Carboxylic Acid Derivatives
The present invention is concerned with novel arylalkyl carboxylic acid derivatives, more specifically, with acylates of arylalkyl carboxylic acids with naturally occurring, non-toxic hydroxy,...
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US20090247628 |
SUBSTITUTED PHENYLCYCLOHEXYLGLYCOLATES
Disclosed herein are substituted phenylcyclohexylglycolate-based muscarinic acetylcholine receptor modulators of Formula I, processes of preparation thereof, pharmaceutical compositions thereof,...
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US20090203759 |
PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS
The present invention relates to a pharmaceutical formulation comprising:
a) one or more NO-releasing NSAID(s) of formula (I);
b) one or more surfactants; c) a carbonyl scavenger compound...
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US20090182033 |
Cyclic Amine Derivatives and Their Uses
Compounds of formula (I) have muscarinic M3 receptor modulating activity; formula (I) wherein R 1 is C 1 -C 6 -alkyl or a hydrogen atom; and R 2 is a hydrogen atom or a group -R 5 or a group,...
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US20090176698 |
Benzimidazolone Derivatives for the Treatment of Urinary Incontinence
The invention relates to compositions comprising benzimidazolone derivatives of formula (I), optionally in form of the free base or in form of the pharmacologically acceptable acid addition salts...
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US20090163487 |
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS
The invention relates to N-hydroxylsulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of...
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US20090163457 |
Compositions and methods for delivering a biologically active agent
The invention relates to codrugs having improved properties, methods for preparing and administering them, and methods of formulating and administering the codrugs as pharmaceutical preparations....
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US20090149534 |
Crystalline modifications of (1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol
Crystalline modifications of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol, pharmaceutical compositions which contain these modifications, and the use thereof to treat pain or other...
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US20090124669 |
Structural Analogues of Avenanthramides, Their Use in Compositions Useful in the Treatment of Dermatological Disorders
Novel compounds for the prevention and treatment of dermatological disorders with an immunoallergic, hyperproliferative and inflammatory component, and a method of producing such compounds. The...
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US20090093510 |
Use of Nitrooxyderivatives of Drug for the Treatment of Muscular Dystrophies
The present invention relates to the use of nitric oxide releasing compounds for retarding or reversing muscular dystrophies such as Duchenne and Becker dystrophies.
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US20090088438 |
NEW TYROSINE DERIVATIVES AS PPARy MODULATORS
Compounds of general formula I,
and the salts and solvates thereof, wherein R1 represents the radical 2-benzoylphenylamino; R2 represents —(CH 2 ) s —N(COR3)-A-J-T or —(CH 2 ) s...
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US20090076144 |
DEUTERIUM-ENRICHED BAZEDOXIFENE
The present application describes deuterium-enriched bazedoxifene, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
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US20090062326 |
M3 MUSCARINIC RECEPTOR ANTAGONISTS FOR TREATMENT OF M3 MUSCARINIC RECEPTOR-EXPRESSING TUMORS
The present disclosure provides methods of treating a tumor using M3 muscarininc receptor antagonists, such as darifenacin. In some examples, the tumor expresses M3 muscarinic receptors, such as...
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US20090054450 |
COMPOSITIONS AND METHODS OF USE FOR TREATING OR PREVENTING LIPID RELATED DISORDERS
Disclosed herein are novel compositions and methods for treating or preventing a variety of disorders and conditions associated with lipid metabolism. The methods generally include administering to...
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US20090048234 |
Pharmaceutical compositions and methods for preventing, treating, or reversing neuronal dysfunction
The present invention provides compositions and methods for preventing, treating or reversing neuronal dysfunction in a mammal resulting from exposure to organophosphate nerve agents,...
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US20090042976 |
Antimicrobial therapy for bacterial infections
The disclosure provides a molecular genetic approach of targeted mutagenesis and heterologous expression, coupled with in vitro and in vivo models of bacterial pathogenesis, to demonstrate that the...
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US20090036527 |
Therapeutic Application Of Leonurine In Treating Cardiomyopathy
The present invention provides methods for treating ischemic cardiomyopathy. In one embodiment, provided is a method of treating a disease characterized as ischemic cardiomyopathy, comprising...
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US20090036526 |
CRYSTAL OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE 1/4 HYDRATE
The present invention provides ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methy
lethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride ¼ hydrate or a crystal thereof which...
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US20090036515 |
METHOD FOR TREATING COLONIC VISCEROSENSITIVITY AND SPASTICITY
There is provided a method of treating colonic viscerosensitivity and spasticity induced by a colonic examination chosen from colonic endoscopy and of barium/air contrast colonic radiography and...
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US20090018161 |
METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION
The present invention provides a more effective gastrointestinal function promoter. The present invention also provides a method for the prophylaxis or improvement of functional gastrointestinal...
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US20080299207 |
METHODS AND COMPOSITIONS FOR ADMINISTRATION OF OXYBUTYNIN
Administration of Oxybutynin in nebulized dry powder form directly to a patient's lungs for treating urinary incontinence or respiratory disease.
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US20080287441 |
ALPHA-(TRIFLUOROMETHYL-SUBSTITUTED ARYLOXY, ARYLAMINO, ARYLTHIO OR ARYLMETHYL)-TRIFLUOROMETHYL-SUBSTITUTED PHENYLACETIC ACIDS AND DERIVATIVES AS ANTIDIABETIC AGENTS
Compounds having a formula:
or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders.
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US20080275080 |
Methods for treating lower urinary tract disorders using alpha2delta subunit channel modulators with smooth muscle modulators
A method is provided for using α 2 δ subunit calcium channel modulators or other compounds that interact with the α 2 δ calcium channel subunit in combination with one or more compounds with...
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US20080269323 |
USE OF 4-(NITROOXY)-BUTYL-(S)-2-(6-METHOXY-2-NAPHTHYL)-PROPANOATE FOR TREATING PAIN AND INFLAMMATION
The present invention relates to the use of 4-(Nitrooxy)-butyl-(S)-2-(6-methoxy-2-naphthyl)-propanoate (naproxcinod) for treating pain and inflammation, in particular musculo-skeletal disorders, in...
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US20080269189 |
Method for Avoiding Edema in the Treatment or Prevention of Ppary-Responsive Diseases, Including Cancer
Compounds, compositions, and methods of avoiding edema while treating or preventing PPARγ-mediated diseases, including cancer, using derivatives and prodrugs are provided.
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US20080234233 |
MEDICAMENT FOR TREATMENT OF NEURODEGENERATIVE DISEASES
A medicament for preventive and/or therapeutic treatment of neurodegenerative diseases such as Alzheimer's disease or the like which comprises as an active ingredient a substance selected from the...
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US20080226698 |
Amorphous drug transdermal systems, manufacturing methods, and stabilization
The present invention refers to a transdermal delivery device comprising a backing layer, an adhesive matrix layer comprising a supersaturated concentration of an active agent substantially in...
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US20080226697 |
Patch for External Use with Elevated Content of Absorption Promoter in Pressure-Sensitive Adhesive Base
A pressure-sensitive adhesive composition for transdermal absorption which contains a drug and a transdermal absorption promoter for the drug, characterized by further containing...
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US20080220092 |
Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep...
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US20080207737 |
Methods for the Treatment of Hyperhidrosis
The present invention relates in general to methods of treating sweating disorders and in particular to topical compositions for the treatment of hyperhidrosis. The methods of the present invention...
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US20080182899 |
ASSOCIATION OF BETA3 RECEPTOR AGONIST AND MONOAMINE REUPTAKE INHIBITORS, PHARMACEUTICAL COMPOSITION AND THERAPEUTIC USE THEREOF
The invention concerns the association of at least one β3 adrenergic receptor agonist (or β3 agonist) with a monoamine reuptake inhibitor. The invention also concerns a pharmaceutical composition...
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US20080153701 |
Fungicidal Mixtures
Fungicidal mixtures, comprising as active components
1) carbamate oxime ethers of the formula I,
in which X is N or CH,
and
2) at least one active compound II selected...
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US20080146662 |
Methods and compositions for treatment of cancer pain
The invention provides a method of treating cancer pain, e.g. bone cancer pain, in a subject in need of such treatment which comprises administering to the subject an effective amount of a COX-2...
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US20080131439 |
METHODS OF DIAGNOSING INFLAMMATORY BOWEL DISEASE
The present invention provides methods, systems, and code for accurately classifying whether a sample from an individual is associated with inflammatory bowel disease (IBD) or a clinical subtype...
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US20080118570 |
POLYMER COATED DRUG-ION EXCHANGE RESINS AND METHODS
Included are compositions, and methods of making, coated controlled-release drug and ion exchange resin form complexes. Methacrylate coatings, which can be free of plasticizers particularly with...
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US20080113919 |
Conjugated Nitro Alkene Anticancer Agents Based on Isoprenoid Metabolism
Conjugated nitro alkene compounds hamper or prevent proliferation of cancer cells in cell culture and in cancer patients, which can result in a decrease in tumor size and/or disappearance of the...
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US20080103144 |
Fungicidal mixtures based on amide compounds and morpholine or piperidine derivatives
Fungicidal mixtures comprise as active components a) an amide compound of the formula I
A—CO—NR 1 R 2 I
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US20080058362 |
Novel pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
Chronic pain is alleviated in a mammal suffering there from by administering to the mammal a chronic pain alleviating amount of a nontoxic N-methyl-D-aspartate receptor antagonist such as...
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US20080057129 |
Drug microparticles
Pharmaceutical compositions are described containing carrier particles bearing microparticles of a drug. The drug microparticles may be deposited on the carrier particles, for example, by...
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US20080039523 |
High volume and alternative methods of delivering homeopathic remedies
An alternative method of delivery of homeopathic medicines by targeting delivery to the MALT's, especially of the intestinal tract and in high volumes.
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US20080038328 |
Pasting Preparation
The patch preparation of the present invention is a patch preparation comprising a backing and an adhesive layer provided on the backing; wherein, the adhesive layer contains (A) a volatile organic...
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US20080004251 |
Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor
The invention provides compounds of formula I or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester,...
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