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US20120100229 Treatment and Prevention of White Matter Injury with KATP Channel Activators  
The present invention includes a method of treating or preventing a CNS white matter injury in a patient in need thereof. The invention also includes a method of stimulating proliferation of a CNS...
US20110015134 Method of treatment for early stage cancer  
This patent describes a method and materials to treat cancer diagnosed at an early stage, particularly breast cancer. It considers that metastatic breast cancer growth includes periods of...
US20110237563 FAST DISSOLVING DRUG DELIVERY SYSTEMS  
The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition,...
US20110268820 USE OF SELECTIVE ESTROGEN RECEPTOR MODULATOR FOR JOINT FUSION AND OTHER REPAIR OR HEALING OF CONNECTIVE TISSUE  
Methods for facilitating joint immobilization or fusion using selective estrogen receptor modulator (SERM) such as raloxifene are disclosed. The SERM may be administered systemically or locally....
US20110092562 Method for wetting a powder containing benzoyl peroxide  
Powder containing benzoyl peroxide is readily wetted by contacting the powder with a liquid containing water and one or more water-soluble organic solvents in a concentration sufficient to reduce...
US20100310680 COMPOSITION AND METHOD FOR TREATING ACNE  
This invention relates to a novel composition and method useful for the treatment of acne, and more particularly, to a composition and method for reducing an appearance of post acne marks and...
US20120046334 PYRROLIDINE-SUBSTITUTED FLAVONES AS RADIO-SENSITIZERS FOR USE IN THE TREATMENT OF CANCER  
The present invention relates to a combination for the treatment of cancer wherein the combination exhibits a synergistic effect. The combination comprises radiation and at least one cyclin...
US20110311629 NON-ADHESIVE ELASTIC GELATIN MATRICES  
The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix...
US20110256203 POROUS CERAMIC SCAFFOLD HAVING AN ORGANIC/INORGANIC HYBRID COATING LAYER CONTAINING BIOACTIVE FACTOR AND METHOD THEREOF  
A method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid composite coating layer containing a bioactive factor is disclosed. The method includes; forming a porous...
US20100324110 Self Solidifying Bioerodible Barrier Implant  
Provided are bioerodible compositions that can be implanted into cavities of mammalian tissue as a liquid or semi-liquid and which solidify upon exposure to body temperature of the mammal. The...
US20110244051 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF OVERACTIVE BLADDER  
Disclosed herein are pharmaceutical compositions comprising a plurality of first beads each comprising: a core; a first layer comprising pilocarpine or a pharmaceutically acceptable salt thereof;...
US20140179752 METHODS OF TREATING SOFT TISSUE DEFECTS  
The specification discloses compositions and methods for treating a soft tissue defect of an individual.
US20100305185 DIAGNOSTIC METHOD  
It has been demonstrated that the level of HBP increases in individuals that subsequently develop severe sepsis. Accordingly, the level of HBP, HBP/WBC ratio or HBP/NC ratio in an individual can...
US20150104491 SUSTAINED-RELEASE RESERVOIR IMPLANTS FOR INTRACAMERAL DRUG DELIVERY  
The present invention provides a sustained release implant for intraocular use to treat elevated intraocular pressure, which implant is configured for intracameral or anterior vitreal...
US20130017243 SUSTAINED-RELEASE RESERVOIR IMPLANTS FOR INTRACAMERAL DRUG DELIVERY  
The present invention provides a sustained release implant for intraocular use to treat elevated intraocular pressure, which implant is configured for intracameral or anterior vitreal...
US20140186329 POLYPHENOL ANALOGS TO TREAT ISCHEMIA  
The present invention provides methods of use of polyphenol compounds for treating, preventing, mitigating and delaying ischemia or a condition where ischemia occurs. In one embodiment, the method...
US20150258080 THERAPEUTIC COMBINATIONS WITH ESTROGEN RECEPTOR MODULATORS  
Described herein are therapeutic combinations with estrogen receptor modulators for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
US20110065748 COMPOSITIONS AND METHODS FOR TREATING DISORDERS OF GASTROINTESTINAL MOTILITY  
Disclosed are methods of treating disorders of gastrointestinal motility by administering to a patient in need of such treatment a compound having the following formula:
US20120295936 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS  
Disclosed are methods of treating a seizure disorder by administering to a patient in need of such treatment a compound having the following formula:
US20110065747 COMPOSITIONS AND METHODS FOR TREATING SEIZURE DISORDERS  
Disclosed are methods of treating a seizure disorder by administering to a patient in need of such treatment a compound having the following formula:
US20110305640 METHOD TO TREAT PSORIASIS AND OTHER HYPERPROLIFERATIVE SKIN DISORDERS  
Soluble adenylyl cyclase (sAC) is implicated in proliferation of keratinocytes. Inhibitors of sAC are useful for the treatment and/or prevention of psoriasis and other hyperproliferative skin...
US20150218121 PRODRUGS OF TETRAHYDROCANNABINOL, COMPOSITIONS COMPRISING PRODRUGS OF TETRAHYDROCANNABINOL AND METHODS OF USING THE SAME  
Described herein are Δ9-THC prodrugs, methods of making Δ9-THC prodrugs, formulations comprising Δ9-THC prodrugs and methods of using Δ9-THC. One embodiment described herein relates to the...
US20120289484 PRODRUGS OF TETRAHYDROCANNABINOL, COMPOSITIONS COMPRISING PRODRUGS OF TETRAHYDROCANNABINOL AND METHODS OF USING THE SAME  
Described herein are Δ9-THC prodrugs, methods of making Δ9-THC prodrugs, formulations comprising Δ9-THC prodrugs and methods of using Δ9-THC. One embodiment described herein relates to the...
US20130345149 SILICONE-BASED OPHTHALMIC FORMULATIONS  
Compositions, products and methods including silicone based excipients are provided. The compositions, products and methods of the present invention are particularly useful for the treatment of...
US20120225827 SILICONE-BASED OPHTHALMIC FORMULATIONS  
Compositions, products and methods including silicone based excipients are provided. The compositions, products and methods of the present invention are particularly useful for the treatment of...
US20150044239 Compositions and Methods for Diagnosing, Preventing and Treating Intracranial Aneurysms  
The present invention relates to compositions and methods for diagnosing, preventing and treating intracranial aneurysm.
US20130109698 Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein  
The present invention includes a method of inhibiting, suppressing or preventing retroviral infection in a subject in need thereof, comprising administering to the subject a pharmaceutical...
US20140112918 SYNERGISTIC PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK  
The present invention relates to a pharmaceutical combination for use in the treatment of squamous cell carcinoma, comprising a CDK inhibitor selected from the compounds of formula (I); or a...
US20110142797 Method For Prophylaxis or Treatment of Feline Infectious Peritonitis  
Provided is a method for treatment and/or prophylaxis of FIP in cats. The method is performed by administering to a cat a composition comprising a therapeutic and/or prophylactic amount of a...
US20120321637 COMBINATION CANCER THERAPY WITH HERV INHIBITION  
Embodiments are directed to compositions and methods related combination therapy with HERV inhibition.
US20150133442 METHODS AND COMPOSITIONS FOR THE INHIBITION OF PIN1  
The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.
US20130281486 2,3-DIHYDROBENZO(1,4) DIOXIN-2-YLMETHYL DERIVATIVES AS ALPHA2C ANTAGONISTS FOR USE IN THE TREATMENT OF PERIPHERIC AND CENTRAL NERVOUS SYSTEM DISEASES  
Compounds of formula I wherein X, Z, R1-R4, and m are as defined in the claims, exhibit alpha2C antagonistic activity, and are thus useful as alpha2C antagonists. Methods for the treatment of...
US20110257130 Compositions and Methods for Treatment of Renin-Angiotensin Aldosterone System (RAAS)- Related Disorders  
Compounds are provided which can be useful in reducing the activity of an angiotensin-converting enzyme and thus be used to treat or prevent a renin-angiotensin aldosterone system-related...
US20150258099 METHODS AND COMPOSITIONS FOR MODULATING ESTROGEN RECEPTOR MUTANTS  
Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also...
US20120108592 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES  
A new class of salicylanilides is described. These compounds show strong activity against hepatitis viruses.
US20110288076 Sphingosine-1-Phosphate Receptor Antagonists  
This disclosure relates to sphingosine-1-phosphate (S1P) receptor antagonists, compositions comprising the S1P receptor antagonists and methods for using and processes for making the S1P receptor...
US20120004162 Methods of Treating an Overweight or Obese Subject  
The disclosure herein generally relates to methods of treating an over eight or obese condition, and overweight- or obesity-related conditions. In one embodiment, the disclosure provides a method...
US20150080381 METHODS OF TREATING ALOPECIA AND ACNE  
Method of treating alopecia and acne with are disclosed. The compounds fall within described by formula I or II:
US20110281853 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ATRIAL FIBRILLATION  
The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides administration of muscarinic receptor...
US20120195976 METHODS OF TREATING INFLAMMATION BY ADMINISTRATION OF HEME OXYGENASE-1 AND PRODUCTS OF HEME DEGRADATION  
The present invention relates to the treatment of disorders using heme oxygenase-1 and heme degradation products.
US20110009353 TARGETING CDK4 AND CDK6 IN CANCER THERAPY  
The invention involves methods of inhibiting the cancer cell cycle to make cancer cells more susceptible to chemotherapeutic agents. In particular, inhibition of CDK4 and/or CDK6 inhibits cell...
US20110263567 COMPOUNDS FOR INHIBITING SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) / VASCULAR ADHESION PROTEIN-1 (VAP-1) AND USES THEREOF FOR TREATMENT AND PREVENTION OF DISEASES  
The present invention relates to compounds of general formula (i) having an oxime moiety or a pharmaceutically acceptable salt, hydrate or solvate thereof and its use for inhibiting...
US20120277222 TREATING VARIOUS DISORDERS USING TRKB AGONISTS  
Novel compounds and methods for activating the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of a compound containing four...
US20110144096 TREATING VARIOUS DISORDERS USING TRKB AGONISTS  
Novel compounds and methods for activating the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of a compound containing four...
US20140140997 Methods of Treating Retroviral Infections in Felines  
Provided are methods for treating or reducing the likelihood of developing a retroviral infection in a feline, decreasing retroviral virion entry into a feline cell, decreasing retroviral virion...
US20100190705 Suppression of glial fibrillary acidic protein  
Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell....
US20150223452 COMPOSITION COMPRISING A PESTICIDAL TERPENE MIXTURE AND A FUNGICIDE  
The present invention relates to a composition comprising a) a pesticidal terpene mixture comprising, as pesticidally active chemical compounds α-terpinene, p-cymene and limonene, and b) at least...
US20140066426 FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES  
The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these...
US20140080780 identification of compounds that disperse tdp-43 inclusions  
Herein, methods of modulating inclusion formation and stress granules in cells are described. The methods comprise contacting a cell with an inclusion inhibitor. Methods for screening for...
US20130022660 DRUG DELIVERY SYSTEM FOR THE PREVENTION OF CEREBRAL VASOSPASM  
The present invention relates to the treatment and prevention of vasospasm. The present invention provides a system for treating a cerebral vasospasm in a human utilizing a pharmaceutical...