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US20140193501 Pulmonary Delivery in Treating Disorders of the Central Nervous System  
A method for treating a disorder of the central nervous system includes administering to the respiratory tract of a patient a drug which is delivered to the pulmonary system, for instance to the...
US20110046120 TREATMENT OF IMPULSE CONTROL DISORDERS  
The present disclosure provides methods and compositions for treating Impulse Control disorders including, for example, pathological gambling using α2-adrenergic agonists, β-adrenergic receptor...
US20150209353 APPLICATION OF 5-HT6 RECEPTOR ANTAGONISTS FOR THE ALLEVIATION OF COGNITIVE DEFICITS OF DOWN SYNDROME  
Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT6) receptor antagonists...
US20130210829 APPLICATION OF 5-HT6 RECEPTOR ANTAGONISTS FOR THE ALLEVIATION OF COGNITIVE DEFICITS OF DOWN SYNDROME  
Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT6) receptor antagonists...
US20140194484 Method of Treating Cachexia and Sarcopenia  
The present invention relates to a method of treating a cachexia and/or sarcopenia with an oral dose of S-pindolol or a pharmaceutical formulation thereof and to an oral formulation for use in...
US20090029970 PAIN REMEDY CONTAINING ROCK INHIBITOR  
Since a ROCK inhibitor exerts a potent analgesic effect by a single dose after the onset of a cartilage-related disease such as osteoarthritis, and can regenerate or suppress destruction of...
US20120264703 Methods And Compositions For The Treatment Of Anxiety Disorders, Including Post Traumatic Stress Disorder (PTSD) And Related Central Nervous System (CNS) Disorders.  
The present invention provides novel methods and formulations for treating anxiety disorders, including Post Traumatic Stress Disorder, in human subjects employing coordinate treatment using α and...
US20120184556 SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS  
Disclosed are substituted benzoimidazolesulfonamides and substituted indolesulfonamides as mGluR4 potentiators.
US20110065661 PHARMACOPERONES FOR CORRECTING DISEASE STATES INVOLVING PROTEIN MISFOLDING  
This application relates to methods of identifying pharmacoperone agents that can restore function to a misfolded protein, such as a misfolded protein that causes disease. Also disclosed are...
US20120178757 Method For The Prevention Of Cancer Metastasis  
A method is provided for the prevention of cancer metastasis in a patient comprising administering an adrenergic receptor antagonist to a patient in need thereof. The invention also includes an...
US20110171325 Systems and Methods for Treating Pain Using Brain Stimulation  
The invention comprises systems and methods for treating nociceptive pain including at least one force-regulatable device in mechanical, electrical, or chemical communication with at least one...
US20150250763 COMBINATION FOR THE PROPHYLAXIS AND TREATMENT OF BEHAVIOURAL, MENTAL, AND COGNITIVE DISORDERS  
The invention relates to the field of pharmacology and practical medicine, namely, to the combined use of pharmaceutical compositions exhibiting a neurotropic action, alleviating manifestations of...
US20110237563 FAST DISSOLVING DRUG DELIVERY SYSTEMS  
The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition,...
US20130231311 NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE  
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,...
US20110118189 NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE  
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,...
US20120238601 TREATMENT OF CANCER  
The present invention provides compositions of matter, kits and methods for their use in the treatment of cancer. In particular, the invention provides compositions and methods for treating cancer...
US20110014205 METHODS AND COMPOSITIONS FOR TREATING CHRONIC PELVIC PAIN SYNDROME  
The present invention provides methods and compositions for treating chronic pelvic pain syndrome. In particular, the present invention provides methods and compositions for treating chronic...
US20140163452 PHARMACOKINETICS OF IONTOPHORETIC SUMATRIPTAN ADMINISTRATION  
Improved pharmacokinetic profiles for the iontophoretic delivery of sumatriptan are described.
US20140005135 STABLE FORMULATIONS FOR PARENTERAL INJECTION OF SMALL MOLECULE DRUGS  
Disclosed is a stable liquid formulation for parenteral injection comprising a biocompatible non-aqueous solvent and a small molecule drug, or a salt thereof, solubilized within the non-aqueous...
US20120270876 Treatment of Conditions Through Pharmacological Modulation of the Autonomic Nervous System  
Methods are provided for treating a subject for a condition caused by an abnormality in the subject's autonomic nervous system. In accordance with the subject methods, at least a portion of a...
US20120095070 PREVENTION AND TREATMENT OF SARCOPENIA  
The present invention provides a means for prevention and treatment of sarcopenia by administration of a substance that both reduces the sensibility of beta-adrenergic receptors and of 5-HT1a...
US20110177167 Hydrophilic/Lipophilic Polymeric Matrix Dosage Formulation  
An oral dosage form comprising a pharmaceutical tablet of one or more layers, one of which carries a biologically active substance; the formulation of said tablet includes different percentages of...
US20120114663 METHODS TO TREAT ALLERGIC CONDITIONS  
Disclosed are methods to treat allergic conditions, including pulmonary and non-pulmonary conditions, in a subject by administering a composition that inhibits Pim kinase. Also disclosed are...
US20110130435 TIME-RELEASED MEDICATION FOR APPLYING TO CRUSTACEAN OVARIAN DEVELOPMENT  
A time-released medication for applying to crustacean ovarian development comprises a covering oil and a serotonin-related reagent. The covering oil is coated with the serotonin-related reagent...
US20150164792 Vaporized Medicants and Methods of Use  
A method and formulation for delivering an active compound in a vaporized state using low temperatures to vaporize the formulation. The formulation contains an inert non-reactive compound that...
US20110217262 Treatment of Ocular Surface Disorders by Increasing Conjunctival Vascular Permeability  
A method of treating an ocular surface disorder in a subject in need of such treatment is provided. The method includes exposing conjunctival tissue of the subject to an effective amount of a...
US20140170215 ORALLY DISINTEGRATING TABLETS AND METHODS OF MANUFACTURE  
A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture...
US20110124657 METHOD FOR SCREENING OF 5HT7 RECEPTOR LIGANDS BASED ON A NEW PHARMACOPHORE MODEL AND A DESCRIPTOR'S PROFILE FILTER  
The present invention relates to compounds having pharmacological activity towards the 5-HT7 receptor; to a method for identifying them as 5-HT7 ligands, especially as agonists, by using a...
US20150174138 DIAGNOSTIC AND TREATMENT METHODS IN SUBJECTS HAVING OR AT RISK OF DEVELOPING RESISTANCE TO CANCER THERAPY  
The invention relates to methods of treatment and diagnosis of subjects with cancer. In some aspects, the invention relates to methods of treatment and diagnosis of subjects with cancer, wherein...
US20130210826 METHODS FOR TREATING PAIN  
The present invention features methods and compositions for preventing, reducing, or treating a traumatic, metabolic, or toxic peripheral nerve lesion or pain including neuropathic pain,...
US20110008412 Oral Formulations for 5-HT-Receptor Agonists, Uses and Methods of Treatment Employing The Same  
A pharmaceutically acceptable oral formulation comprising core material which comprises a therapeutically effective amount of a 5-HT-receptor agonist, or a pharmaceutically acceptable salt,...
US20100324105 Methods of Reducing Serum Glucose and Triglyceride Levels and for Inhibiting Angiogenesis Using Substituted Indolealkanoic Acids  
Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in...
US20150258064 MELATONIN-BASED FORMULATIONS FOR PARENTERAL ADMINISTRATION  
Pharmaceutical formulations comprising nanoparticles of melatonin are useful for the treatment of neonatal brain injury.
US20110319464 METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA  
Patients having symptoms associated with benign prostatic hyperplasia can be treated with a once daily composition containing silodosin or a pharmaceutically acceptable salt thereof.
US20110207753 METHODS FOR TREATING PAIN  
The present invention features methods and compositions for preventing, reducing, or treating a traumatic, metabolic or toxic peripheral nerve lesion or pain including, for example, neuropathic...
US20140148439 USE OF ANTIOXIDANTS FOR THE TREATMENT OF COGNITIVE AND BEHAVIOURAL DISORDERS IN INDIVIDUALS WITH FRAGILE X SYNDROME  
The invention relates to the use of antioxidants such as, ascorbic acid (Vitamin C), Tocopherol (Vitamin E), vitamin A and polyphenols, for the treatment of cognitive and behavioural disorders in...
US20110152272 Treatment Of Incontinence  
The present invention relates to the use of agonists of 5-HT2C receptors for the treatment of urinary incontinence, preferably mixed incontinence or stress urinary incontinence. The invention also...
US20120100223 LIPID-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF  
Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed around and including the...
US20130317030 Methods for Diagnosis of Cardiovascular Disease  
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to...
US20120107401 OSTEOCONDUCTIVE MATRICES COMPRISING STATINS AND METHODS OF USING THE SAME  
Osteoconductive matrices and methods are provided that have one or more statins disposed therein. The matrices may be injected into a fracture site. The osteoconductive matrices provided allow for...
US20120263790 METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS  
Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia,...
US20130296230 METHOD FOR TREATING MALARIA, METHOD FOR KILLING MALARIA PARASITE, AND USE OF THE METHODS  
A method of the present invention for treating malaria includes the step of administering, to a human or an animal, a therapeutically effective amount of drug for suppressing calcium ion exit from...
US20140037622 HUMAN PAPILLOMA VIRUS AS PREDICTOR OF CANCER PROGNOSIS  
Methods of treating a head and neck cancer are disclosed.
US20140308357 MELATONIN-BASED SOLUTIONS AND POWDERS FOR THEIR PREPARATION  
The present invention relates to a powder for reconstitution before use for preparations for injection containing melatonin, at least one soluble excipient and at least one surfactant for the...
US20130315981 METHOD FOR INDUCING FAT LOSS IN MAMMALS  
The present invention is a method of increasing lipolysis in an adipose tissue of a mammal comprising delivering to macrophages at the adipose tissue of the mammal an effective amount of an agent...
US20110195932 Drug Combinations for the Treatment of Duchenne Muscular Dystrophy  
Combinations comprising (or consisting essentially of) one or more compounds of formula (1) with one or more ancillary agents, to processes for preparing the combinations, and to various...
US20120107383 OSTEOCONDUCTIVE MATRICES COMPRISING CALCIUM PHOSPHATE PARTICLES AND STATINS AND METHODS OF USING THE SAME  
Osteoconductive matrices and methods are provided that have one or more statins disposed in calcium phosphate particles. The matrices may be injected into a fracture site. The osteoconductive...
US20100317703 METHOD FOR INHIBITING BRASSININ OXIDASE  
The present disclosure relates to a method for inhibiting brassinin oxidase comprising treating a pathogen that is producing BO with an effective amount of selected Paldoxin compounds.
US20110158983 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES  
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any...
US20130045217 LIPIDOMIC BIOMARKERS FOR ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE  
The present invention inter alia provides a method, and use thereof, of diagnosing and/or predicting atherosclerosis or CVD by detecting the lipid concentrations or lipid ratios of a biological...