|
Match
|
Document |
Document Title |
|
|
US20090270859 |
FLUID COMPOSITIONS AND METHODS FOR THE USE THEREOF
A method of performing transurethral surgery on the human or animal body. A tissue is cut using a first active cutting electrode and a second neutral electrode, both electrodes being immersed in an...
|
|
|
US20090264492 |
PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF A FUNGAL SKIN DISORDER AND A METHOD FOR THE PREPARATION THEREOF
The present invention relates to a pharmaceutical composition for photodynamic treatment of a fungal skin disorder, said pharmaceutical composition comprising a photosensitizer and an enhancer,...
|
|
|
US20090239925 |
TRICYCLIC INDENO-PYRROLE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS
The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More...
|
|
|
US20090227650 |
Novel crystalline forms of Lestaurtinib
Novel crystalline forms of lestaurtinib are described, including six co-crystal forms, nineteen solvate forms, three anhydrate forms and one hemihydrate form. Methods of their preparation and use...
|
|
|
US20090227553 |
SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES
The present invention provides compounds of the general Formula DI: along with methods of making such compounds, formulations containing the same, and methods of using the same (e.g., in...
|
|
|
US20090226467 |
DE NOVO SYNTHESIS OF BACTERIOCHLORINS
A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II
to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may...
|
|
|
US20090220420 |
TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR)
The present invention provides novel tetracyclic indole compounds of Formula (I) either as in vivo imaging agents or as therapeutic agents. A method for the preparation of the in vivo imaging agent...
|
|
|
US20090215851 |
Method of Preparing a Porphyrin Derivative, a Porphyrin Derivative, Use of Said Porphyrin derivative and a pharmaceutical composition containing said porphyrin derivative
The present invention relates to a method of preparing a porphyrin derivative from a meso-acrylonitrile-substituted porphyrin compound. According to the invention a Vilsmeier reagent carrying an...
|
|
|
US20090209608 |
DEUTERIUM-ENRICHED ASENAPINE
The present application describes deuterium-enriched asenapine, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
|
|
|
US20090209508 |
Compounds for Photochemotherapy
Enzyme-activatable photosensitizing polymer conjugates are disclosed for photochemotherapeutic treatment of human diseases and disorders, bacteriologic or virologic indications, cosmetic...
|
|
|
US20090203757 |
ETHYLENE GLYCOL ESTERS AS PHOTOACTIVE AGENTS
New compounds useful in photodynamic therapy are of the formula
and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof
wherein each R 1 is...
|
|
|
US20090197856 |
ANTIVIRAL COMPOUNDS
Provided are compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds and compositions are useful for treating viral infections caused by the Flaviviridae...
|
|
|
US20090197853 |
METHODS AND COMPOSITIONS OF TREATING CANCER
The present disclosure involves the use of metal-containing texaphyrins and zinc (II) reagents for the treatment of tumors, atheromas and other neoplastic tissue. The present application...
|
|
|
US20090192209 |
Extended treatment of tumors through vessel occlusion with light activated drugs
Methods of treating diseases of a subject through selective occlusion of blood vessels. The methods include identifying and/or mapping the blood vessels supplying nutrients to the diseased or...
|
|
|
US20090191253 |
Use of K-252a and Kinase Inhibitors for the Prevention or Treatment of HMGB1-Associated Pathologies
The present invention relates to the use of K-252a, a physiologically active substance produced by microorganisms, and of its salts or synthetic and/or chemically modified derivatives for the...
|
|
|
US20090182014 |
INSECTICIDAL COMPOSITIONS COMPRISING COMPOUNDS HAVING INHIBITORY ACTIVITY VERSUS ACYL COA: CHOLESTEROL ACYLTRANSFERASE OR SALTS THEREOF AS EFFECTIVE INGREDIENTS
The present invention relates to insecticidal compositions comprising compounds having an inhibitory activity versus acyl CoA: cholesterol acyltransferase (ACAT) or salts thereof as effective...
|
|
|
US20090176858 |
HCV PROTEASE INHIBITORS AND USES THEREOF
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
|
|
|
US20090176855 |
TREATMENT OF BIPOLAR DISORDERS AND ASSOCIATED SYMPTOMS
The present invention relates to a method and kits for treating bipolar disorder in a mammal, including a human, the treatments including treatment of bipolar disorder including rapid-cycling,...
|
|
|
US20090149527 |
Apparatus and Method for Application of a Pharmaceutical to a Surface of an External Ear Canal for Treatment of Keratosis Obutrans
A packaged kit for treating keratosis obturans includes a plurality of ear needles having different shaped absorbent applicators on distal ends of the needles, a vial of a single dose of an...
|
|
|
US20090149526 |
Tetracyclic Indole Derivatives as Antiviral Agents
The present invention relates to tetracyclic indole derivatives of formula (I): wherein Ar, A, R 1 , R 2 , L, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof,...
|
|
|
US20090149525 |
NOVEL DERIVATIVES OF PORPHYRIN, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS, AND USES THEREOF IN PHOTODYNAMIC THERAPY
The invention relates to derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, which can be used in photodynamic therapy. According to the formulas of the invention, X 1 , X 2 ,...
|
|
|
US20090143457 |
POLYCYCLIC COMPOUNDS FOR USE IN TREATING OCULAR NEURODEGENERATIVE DISEASES
Described herein are various compounds for treatment of ocular neurodegenerative diseases, including but not limited to glaucoma and diabetic retinopathy. The compounds described herein can act to...
|
|
|
US20090143456 |
Polyamine Analogs as Modulators of Cell Migration and Cell Motility
This disclosure relates to methods of inhibiting cell motility or cell migration, and of treating diseases involving cell migration or cell motility, using polyamine analogs, such as...
|
|
|
US20090136449 |
Tetracyclic Indole Derivatives as Antiviral Agents
The present invention relates to tetracyclic indole derivatives of formula (I); wherein Ar, D 1 , D 2 , D 3 , D 4 , W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof,...
|
|
|
US20090131500 |
PORPHYRIN DERIVATES AND THEIR USE AS PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY
The present invention relates to novel porphyrin derivates of formula (I), especially to porphyrins which carry substituted phenyl moieties in meso-position. The porphyrin derivates of the...
|
|
|
US20090131499 |
PHOTODYNAMIC THERAPY FOR SKIN RELATED PROBLEMS
PhotoDynamic Therapy method is used to treat problems associated with pilosebaceous units including acne and other skin conditions. At least one liposomal-formulated, hydrophobic photosensitizer,...
|
|
|
US20090131498 |
Enantioselective Synthesis of Merrilactone and Its Analogs
This invention provides a method of synthesizing enantioenriched merrilactone A and enantiopure merrilactone A, as well as an improved method of synthesizing racemic merrilactone. This invention...
|
|
|
US20090131393 |
Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group
A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitising agents in photodynamic therapy.
|
|
|
US20090124540 |
Anti-adhesion composites and methods of use thereof
Described herein are composites that inhibit or reduce adhesion between two or more tissues. Also described herein are methods of using the composites.
|
|
|
US20090118205 |
Antisense Oligonucleotides Directed to Ribonucleotide Reductase R2 and uses Thereof in the Treatment of Cancer
The present invention provides antisense oligonucleotides directed to a mammalian ribonucleotide reductase R2 gene and combinations of the antisense oligonucleotides with one or more...
|
|
|
US20090105227 |
Thienopyrroles As Antiviral Agents
The present invention relates to tetracyclic thienopyrrole compounds of formula (I), wherein Ar, A, D1, D2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof,...
|
|
|
US20090104212 |
METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS USING TWO-PHOTON SIMULTANEOUS ABSORPTION
A method for treating a cell proliferation disorder in a subject, comprising:
(1) administering to the subject at least one activatable pharmaceutical agent that is capable of activation by...
|
|
|
US20090092550 |
PORPHYRIN LINKED METRONIDAZOLE AGAINST GUM DISEASE: PORPHYROMONAS GINGIVALIS
The present invention relates generally to targeted molecular agents (TMAs) directed to a particular organism or group of organisms and uses thereof. More particularly, the present invention...
|
|
|
US20090088373 |
USE OF COMPOSITIONS TO ENHANCE INNATE IMMUNE RESPONSE
The present invention discloses methods of using of compounds for the enhancement of the innate immune system of a patient. In particular, the active compounds of the present invention include at...
|
|
|
US20090081281 |
Photosensitizer Formulation for Topical Applications
Highly flexible penetrating liposomal carrier systems are formulated with enhanced skin penetration properties. These specialized formulations of highly flexible penetrating liposomal delivery...
|
|
|
US20090076115 |
Photosensitizers for Targeted Photodynamic Therapy
The present invention relates to photosensitizer compounds based on functionalized fullerenes useful in targeted photodynamic therapy (PDT), and methods of use thereof.
|
|
|
US20090075996 |
HETEROTETRACYCLIC COMPOUNDS AS TPO MIMETICS
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated...
|
|
|
US20090075974 |
AGENT FOR PROPHYLAXIS AND TREATMENT OF PANCREATITIS
Disclosed is a pharmaceutical composition for prophylaxis and treatment of pancreatitis comprising a 5-HT2A receptor antagonist as an effective component, wherein the binding activity (pKi) of the...
|
|
|
US20090069220 |
DNA-BINDING POLYAMIDE DRUG CONJUGATES
A conjugate of formula:
V—(Y) a -Z-T (I),
|
|
|
US20090068094 |
INHIBITORS OF ENDO-EXONUCLEASE ACTIVITY FOR TREATING CANCER
The present invention relates to the treatment of cancer with compounds that inhibit the activity of endo-exonuclease. Endo-exonuclease has been shown to be necessary for the repair of damaged DNA....
|
|
|
US20090060905 |
Use of 15-Lipoxygenase Inhibitors for Treating Obesity
The invention concerns the treatment of obesity, in particular abdominal visceral obesity. More specifically, the invention concerns the use of selective 15-lipoxygenase (LO) inhibitors for...
|
|
|
US20090048239 |
Therapeutic compounds
A class of macrocyclic compounds of formula (I), wherein R 7 , A, Ar, B, D, F, M, Q 1 , Q 2 , W, X, Y and Z are defined herein, that are useful as inhibitors of viral proteases, particularly the...
|
|
|
US20090048187 |
Chemopreventive, Anticancer and Anti-Inflammatory Effects of Pinoresinol-Rich Olives
The present invention relates to a composition and method for preventing and treating cancer and modulating cell proliferation using compositions extracted from pinoresinol-rich Olea europaea ...
|
|
|
US20090041835 |
METHOD OF INHIBITING LEAKAGE OF DRUG ENCAPSULATED IN LIPOSOMES
The present invention provides a method of inhibiting the leakage of a drug encapsulated in liposomes, which comprises satisfying at least two requirements selected from the group consisting of the...
|
|
|
US20090041672 |
Drug for Treating or Diagnosing Vascular Lesion in the Skin or the Subcutaneous Soft Tissue Caused by Light Irradiation
A novel drug for treating a vascular lesion in the skin or the subcutaneous soft tissue caused by light irradiation which is efficacious in treating a vascular lesion in the deep part of the skin...
|
|
|
US20090030257 |
Anti-microbial photodynamic therapy
Antimicrobial molecular conjugates for the treatment and prevention of infectious diseases caused by pathogenic microorganisms in human and animals are provided. The key to these conjugates is a...
|
|
|
US20090023721 |
Novel Substituted Tetracyclic Tetrahydrofuran, Pyrrolidine and Tetrahydrothiophene Derivatives and Their Use as a Medicament
This invention concerns novel substituted tetracyclic tetrahydrofuran, pyrrolidine and tetrahydrothiophene derivatives with binding affinities towards serotonin receptors, in particular 5-HT 2A ...
|
|
|
US20080317876 |
USE OF A MAGNESIUM ISOTOPE FOR TREATING HYPOXIA AND A MEDICAMENT COMPRISING THE SAME
The present invention describes the use of the magnetic magnesium isotope 25 Mg 2+ for the manufacture of a medicament for treating hypoxia. Furthermore, the present invention provides a...
|
|
|
US20080317809 |
Use of K -252a and Kinase Inhibitors for the Prevention or Treatment of Hmgb1-Associated Pathologies
The present invention relates to the use of K-252a, a physiologically active substance produced by microorganisms, and of its salts or synthetic and/or chemically modified derivatives for the...
|
|
|
US20080312241 |
Cicletanine and PKC inhibitors in the treatment of pulmonary and cardiac disorders
Embodiments of the present invention are related to novel therapeutic drugs, drug combinations, and associated methods for treating or preventing pulmonary disease, including pulmonary...
|