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US20150238617 SILK RESERVOIRS FOR SUSTAINED DELIVERY OF ANTI-CANCER AGENTS  
The present invention on directed to silk-based drug delivery compositions for sustained delivery of drugs, e.g., for cancer therapy, and methods of their use for treatment.
US20120309625 Biocide Compositions Comprising Carbamates  
Described are biocide compositions, comprising (a) carbamates, (b) biocides and optionally (c) oil components/co-solvents and/or (d) emulsifiers. The compositions have high solubility for biocides...
US20130165491 THERAPEUTIC AGENT FOR PAIN  
[Problem] Provided is a pharmaceutical, in particular, a pharmaceutical composition which is useful for the treatment of pain.[Means for Solution]The present inventors have made extensive studies...
US20140155440 CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS  
The present invention provides cysteine and cystine bioisosteres for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing...
US20110087153 Transdermal Methods And Systems For The Delivery Of Rizatriptan  
Iontophoretic patches for the delivery of rizatriptan and methods of using the patches are described.
US20130136849 SUB-MICRON COMPOSITIONS  
The invention relates to sub-micron compositions, and methods of preparing such compositions, in particular for the treatment of substrates against biological degradation biological pests.
US20060258561 Novel NPH insulin preparations  
This invention relates to NPH-insulin (crystalline preparations) that are prepared in the presence of certain high-affinity ligands for the HisB10 Zn2+-sites of the R-state insulin hexamer....
US20130137738 FUNGICIDAL COMPOSITIONS FOR TURF TREATMENT AND IMPROVEMENT  
The present invention relates to novel compositions comprising: a fungicide that inhibits mitochondrial respiration at the QoI site (QoI inhibitor), a contact fungicide, a demethylation inhibitor,...
US20100016363 Fixed Combination Dosage Forms for the Treatment of Migraine  
Therapeutic regimens and dosage forms are disclosed for the treatment of migraine headache. The regimens preferably combine a serotonin receptor agonist, such as sumatriptan, eletriptan or...
US20120108570 Pharmacological Treatment for Sleep Apnea  
The present invention relates generally to pharmacological methods for the prevention of amelioration of sleep-related breathing disorders via administration of agents or combinations of agents...
US20120178697 Compositions and methods for the inhibition of dishevelled proteins  
The Wnt signaling pathways are involved in embryo development as well as in tumorigenesis. Dishevelled (Dvl) tranduces Wnt signals from the receptor Frizzled (Fz) to downstream components in...
US20120164103 Compounds and Methods for the Treatment or Prevention of Flavivirus Infections  
Compounds represented by formula I: or pharmaceutically acceptable salts and solvates thereof, wherein R1, X, Y, Y1, and Z are as defined herein, are useful for treating flaviviridae viral infections.
US20110207750 BENZIMIDAZOLE AND AZA-BENZIMIDAZOLE CARBOXAMIDES  
This invention provides compounds of Formula I which are PAFR antagonists: I and the pharmaceutically acceptable salts thereof. The compounds are useful for treating PAF-mediated disorders, and...
US20130136719 COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS  
Compounds represented by formula I: or pharmaceutically acceptable salts thereof, wherein R1, R2, and R3 are as defined herein, are useful for treating flaviviridae viral infections.
US20100196509 Methods for Diagnosis and Treatment of Endometrial Cancer  
The present invention discloses methods of using endothelial membrane protein 2 (EMP2) as a biomarker for stratification of endometrial premalignancy, diagnosing, staging and imaging of...
US20050020646 Treatment of BPH  
The present invention relates to the use of EP1 receptor antagonists for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). The invention also...
US20130065763 Biocide Compositions Comprising Isoamyl Lactate  
Suggested are biocide compositions, comprising (a) Isoamyl lactate; (b) Biocides and optionally (c) Oil components or co-solvents and/or (d) Emulsifiers. The compositions show high solubility for...
US20140343347 METHODS AND RELATED COMPOSITIONS FOR THE TREATMENT OF CANCER  
A method of treatment and/or prevention of cancer comprises administering agents which cause increased intracellular granularity in cancer cells, at least in an amount sufficient to inhibit...
US20140073678 ANTI-PAIN AND ANTI-NAUSEA AND/OR VOMITING COMBINATORIAL COMPOSITIONS  
In one aspect, the present invention discloses combinational compositions for treating users experiencing symptoms associated with a migraine or other central nervous system related pain disorder...
US20150225391 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO  
This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used...
US20140275047 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO  
This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used...
US20140274688 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO  
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used...
US20150150850 TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS  
Methods of treating cancer with a compound of formulae (I) or (Ia) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of...
US20140294808 TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS  
Methods of treating cancer with a compound of formulae (I) or (Ia) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of...
US20130177603 Methods for the Preparation of Injectable Depot Compositions  
Injectable depot compositions, comprising a biocompatible polymer which is a polymer or copolymer based on lactic acid and/or lactic acid plus glycolic acid having a monomer ratio of lactic to...
US20120245186 COMBINATION CANCER THERAPY WITH HSP90 INHIBITORY COMPOUNDS  
Disclosed is a method for treating a subject with cancer, comprising administering to the subject an effective amount of paclitaxel or a paclitaxel analogue and an effective amount of a compound...
US20070105927 Amorphous rizatriptan benzoate  
Rizatriptan benzoate in an amorphous form is disclosed. Also disclosed is a process for preparing rizatriptan benzoate substantially in amorphous form comprising the steps of (a) preparing a...
US20120114636 LOW MOLECULAR WEIGHT CYCLIN E (LMW-E) AS A BIOMARKER FOR PERSONALIZATION OF CANCER THERAPIES  
Methods are disclosed for predicting a patient response to anti-Her2 therapy or anti-aromatase therapy. In certain embodiments, the methods involve the identification of low molecular weight...
US20110033519 Device with Aromatase Inhibitor for the Treatment and Prevention of Uterine Fibroids and Method of Use  
The invention provides a device and a compound for the prevention and/or treatment of uterine fibroids in human patients, wherein the compound is dispensed from the device and is administered...
US20120108595 PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS  
Cyclohexyl sulfonamide compounds which are platelet-activating factor (PAF) receptor antagonists. Said compounds may be useful, for example, for the treatment of atherosclerosis or other...
US20110082178 METHODS OF TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES AND DISORDERS  
Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed....
US20120035054 PESTICIDE COMPOSITIONS OF MESO-SIZED PARTICLES WITH ENHANCED ACTIVITY  
The present disclosure relates to pesticide compositions consisting of meso-sized particles in combination with certain adjuvants such as built-in adjuvants which are added directly to the...
US20080025991 Use of Aromatase Inhibitors for Treatment of Ectopic Pregnancy  
Following a diagnosis of ectopic pregnancy, at least one aromatase inhibitor, is administered to a patient, either alone or in combination with other aromatase inhibitors or therapeutic agents or...
US20140094494 Antifungal Treatment  
A method of treating or preventing fungal infection, which includes identifying a plant or animal having a fungal infection and administering an effective amount of an anti-fungal composition to...
US20110319455 Antifungal Treatment  
A method of treating or preventing fungal infection, which includes identifying a plant or animal having a fungal infection and administering an effective amount of an anti-fungal composition to...
US20100184816 Method for Reducing the Phytotoxicity of Azoles on Dicotyledonous Plants by Adding Additives  
The present invention relates to a method for reducing the phytotoxicity of azoles on dicotyledonous plants by addition of additives. Furthermore, the application relates to novel compositions...
US20130310433 THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES  
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of...
US20120165378 THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES  
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of...
US20100004303 TREATMENT OF ENDOCRINE DYSFUNCTION USING IRON CHELATORS  
The invention relates to the use of an iron chelator for the treatment or prevention of pathologies due to iron loading, e.g. related to a dysfunction, in particular a reduction or inhibition, of...
US20100056426 USE OF IRON CHELATOR FOR THE TREATMENT OF MYOCARDIAL INFARCTION  
The present invention relates to a method of treating and/or preventing myocardial infarction comprising administering an iron chelator to a warm-blooded animal. The iron chelator is preferably...
US20150126467 USE OF ALGINATE OLIGOMERS TO ENHANCE THE EFFECTS OF ANTIFUNGAL AGENTS  
The disclosure relates to use of alginate oligomers to enhance the effects of antifungal agents. The invention provides a method to improve the efficacy of an antifungal agent against a fungus,...
US20150065504 ANTIVIRAL COMPOUNDS  
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein...
US20090093472 ORTHO PYRROLIDINE, BENZYL-SUBSTITUTED HETEROCYCLE CCR1 ANTAGONISTS FOR AUTOIMMUNE DISEASES & INFLAMMATION  
Compounds of the formula are disclosed. The compounds are CCR1 antagonists which are useful for the treatment and prevention of inflammatory and autoimmune diseases. Other embodiments are also...
US20120014962 METHOD OF INHIBITING FIBROGENESIS AND TREATING FIBROTIC DISEASE  
The present invention relates to the discovery of an epigenetic relay pathway that controls hepatic stellate cell activation and the wound-healing response in fibrogenesis, including fibrogenesis...
US20130324481 SUSTAINED RELEASE EYE DROP FORMULATIONS  
This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low...
US20130023571 N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES  
The present invention relates to novel triazole-substituted benzamide derivatives, to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode...
US20110077272 PULMONARY FORMULATIONS OF TRIPTANS  
A pharmaceutical composition includes triptans, such as sumatriptan, and may be used in therapy. The composition may be administered via the inhaled route.
US20120172334 CONTROLLED RELEASE PARTICLES AND METHOD FOR PRODUCING THE SAME  
Controlled release particles are obtained by dissolving a hydrophobic antibiotic compound in a hydrophobic polymerizable vinyl monomer without the presence of a solvent, thereby preparing a...
US20130023539 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43)  
The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases.
US20100324071 NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME  
Compounds are provided which are activators of the enzyme glucokinase and thus are useful in treating diabetes and related diseases, which compounds have the structure where Q is and R1, R2, R3,...