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US20110172278 COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS  
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with or mediated by...
US20150010638 Method for Improving Water Solubility of Slightly Soluble Substance  
It is an object of the present invention to provide a method for improving the solubility of a poorly-soluble substance, which is capable of increasing the solubility of substantially all...
US20110313009 NSAID DOSE UNIT FORMULATIONS WITH H2-RECEPTOR ANTAGONISTS AND METHODS OF USE  
The present invention generally relates to unit dosage forms of naproxen and H2-receptor antagonists, comprising an immediate-release formulation of naproxen; an immediate-release formulation of...
US20140065246 INTRACELLULAR CALCIUM MODULATION FOR CANCER TREATMENT  
Tumor cells exhibit consistent abnormalities in calcium regulation. The present disclosure teaches methods by which such differences are exploited to induce Apoptosis selectively in tumor/cancer...
US20100297224 NSAID Dose Unit Formulations with H2-Receptor Antagonists and Methods of Use  
The present invention generally relates to pharmaceutical unit dosage forms of NSAIDs and H2-receptor antagonists, in which the H2-receptor antagonist is formulated so as to be released in a...
US20120052109 Control of Parasites  
The invention concerns a composition for the treatment of varroa mite infestations in honeybee colonies, comprising a base layer and an active layer, wherein the active layer comprises an...
US20120058186 THERAPEUTIC OR PROPHYLACTIC AGENT FOR DYSKINESIA  
The present invention relates to a stable orally disintegrating coated tablet containing a drug, wherein the tablet is coated with a coating layer containing a water-soluble substance and a...
US20130108688 Delivery of H2 Antagonists  
The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist...
US20140186439 STABLE COMPOSITIONS OF FAMOTIDINE AND IBUPROFEN  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface...
US20130011476 STABLE COMPOSITIONS OF FAMOTIDINE AND IBUPROFEN  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface...
US20130011475 STABLE COMPOSITIONS OF FAMOTIDINE AND IBUPROFEN  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface...
US20120156292 STABLE COMPOSITIONS OF FAMOTIDINE AND IBUPROFEN  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface...
US20120156291 STABLE COMPOSITIONS OF FAMOTIDINE AND IBUPROFEN  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface...
US20120122787 METHODS FOR TREATING POLYCYSTIC KIDNEY DISEASE (PKD) OR OTHER CYST FORMING DISEASES  
The present invention is directed to, inter alia, methods of treating or ameliorating an effect of a polycystic disease. This method include administering to a patient in need thereof an amount of...
US20120157457 COMPOSITIONS AND METHODS FOR INDUCING NEURONAL DIFFERENTIATION  
The present invention provides compositions and methods for inducing neuronal cell differentiation.
US20120128778 COMPOSITIONS AND METHODS FOR ONCE-DAILY ADMINISTRATION OF A TRILAYER OSMOTIC TABLET  
A trilayer osmotic tablet is described. The tablet includes a core, a semi-permeable membrane disposed generally around the core, and an orifice in the semi-permeable membrane in fluid...
US20120148530 Method for the treatment or prevention of virus infection using polybiguanide-based compounds  
An inexpensive, easily available, and convenient method of treating or preventing a virus infection is provided. The present invention relates to a method for the treatment or prevention of virus...
US20130295175 ORALLY DISINTEGRATING TABLET  
The present invention features a tablet containing at least one first material, at least one second material, and at least one pharmaceutically active agent, wherein: (a) the first material is a...
US20150133442 METHODS AND COMPOSITIONS FOR THE INHIBITION OF PIN1  
The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.
US20120316148 Compositions and Methods for Modulating a Kinase  
The invention relates to compounds and methods for modulating one or more components of a kinase signaling cascade.
US20120164139 Dopamine 3 receptor agonist and antagonist treatment of gastrointestinal motility disorders  
Provided herein are methods of treating gastrointestinal motility disorders by targeting the dopamine 3 receptor (D3R). A D3R agonist is administered to a subject to decrease gastrointestinal...
US20140188057 TRANSDERMAL DOSAGE FORM FOR LOW-MELTING POINT ACTIVE AGENT  
A drug-containing patch allows transdermal administration of a drug. The patch features a hydrophobic reservoir containing the drug, where the reservoir has a first surface and a second surface. A...
US20120022122 TREATMENT AND PREVENTION OF DELETERIOUS EFFECTS ASSOCIATED WITH ALCOHOL CONSUMPTION  
The present invention provides to methods and compositions that treat or prevent deleterious effects associated with alcohol consumption including alcohol-induced flush reaction and hangover. The...
US20120122852 TRICYCLIC N-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE  
The invention concerns tricyclic N-heteroaryl-carboxamide derivatives containing a benzimidazole unit of general formula (I): Wherein A, P, Y, R1, R2 and R3 are as defined herein. The invention...
US20140249100 COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS  
Disclosed are methods for preventing metastasis of cancer cells. The disclosed compounds can be used to prevent the spread of tumor or other types of cancer cells.
US20150224056 PHARMACEUTICAL COMPOSITIONS OF IBUPROFEN AND FAMOTIDINE  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
US20130236538 PHARMACEUTICAL COMPOSITIONS OF IBUPROFEN AND FAMOTIDINE  
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
US20140080801 PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE  
Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is thiazolyl,...
US20130203732 PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE  
Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is a thiazolyl,...
US20140357685 Sodium Channel Inhibitors  
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly,...
US20130172277 PHARMACEUTICAL COMBINATION  
Pharmaceutical combinations comprising a beta-3 adrenergic receptor agonist and a muscarinic receptor antagonist, and methods for their use are disclosed. Methods of using the pharmaceutical...
US20110053770 SUBSTITUTED AMINOTHIAZOLES AND THEIR USE AS FUNGICIDES  
The present invention relates to aminothiazoles of the general formula (I), to a process for their preparation, to the use of the aminothiazoles according to the invention for controlling unwanted...
US20120294937 NEW PHARMACEUTICAL DOSAGE FORM FOR THE TREATMENT OF GASTRIC ACID-RELATED DISORDERS  
According to the invention there is provided a capsule for peroral administration to the gastrointestinal tract containing (a) a pharmacologically effective amount of a PPI or a pharmaceutically...
US20150258052 METHODS OF USING FEXARAMINE AND AGENTS THAT INCREASE SYMPATHETIC NERVOUS SYSTEM ACTIVITY TO PROMOTE BROWNING OF WHITE ADIPOSE TISSUE  
Provided are methods of promoting browning of white adipose tissue (WAT) in a subject. Such methods can include administering to a subject (e.g., via the gastrointestinal tract) a therapeutically...
US20140017321 METHODS AND MEDICAMENTS FOR ADMINISTRATION OF IBUPROFEN  
A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a...
US20110311637 METHODS AND MEDICAMENTS FOR ADMINISTRATION OF IBUPROFEN  
A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a...
US20110311636 METHODS AND MEDICAMENTS FOR ADMINISTRATION OF IBUPROFEN  
A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a...
US20150018371 POSITIVE ALLOSTERIC MODULATORS FOR MELANOCORTIN RECEPTORS  
Positive allosteric modulators of melanocortin receptors, especially allosteric potentiators of the receptors MC3R and MC4R are described herein. Also provided are pharmaceutical compositions...
US20120283268 Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers  
Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of...
US20110293673 ORAL FILM-FORM BASE AND ORAL FILM-FORM PREPARATION  
The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a...
US20130338162 COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS  
Disclosed are compounds and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70...
US20130296369 Cyanoenamines and their use as fungicides  
The present invention relates to cyanoenamine derivatives, their process of preparation, intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide...
US20070259931 Process of reducing the bitter taste of water soluble actives by co-grinding the acitve with beta cyclodextrin  
A process for reducing the intensity of the intrinsic bitter taste of a water soluble active which comprises dry mixing of said active with β-cyclodextrin.
US20140322313 PHARMACEUTICAL COMPOSITIONS OF IBUPROFEN AND AN H2 RECEPTOR ANTAGONIST  
Pharmaceutical compositions of a H2 receptor antagonist and ibuprofen are provided herein. The compositions comprise, e.g., a core and a shell separated by a barrier layer, bilayered or trilayered...
US20130078287 PHARMACEUTICAL COMPOSITIONS OF IBUPROFEN AND AN H2 RECEPTOR ANTAGONIST  
Pharmaceutical compositions of a H2 receptor antagonist and ibuprofen are provided herein. The compositions comprise, e.g., a core and a shell separated by a barrier layer, bilayered or trilayered...
US20130072471 Inhibitors of Ion Channels  
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly,...
US20120245166 TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH  
Methods for enhancing memory and/or learning and prevent neurodegeneration by administration of certain heterocyclic and aromatic compounds are described. The methods are particularly useful for...
US20140364433 SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS  
The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a...
US20150164758 TYROSINASE INHIBITORS  
The compositions and methods of described herein comprise novel ingredients effective to reduce unwanted pigmentation, such as skin discoloration, freckles, age spots, liver spots, sun damage,...
US20150111897 TYROSINASE INHIBITORS  
The compositions and methods of described herein comprise novel ingredients effective to reduce unwanted pigmentation, such as skin discoloration, freckles, age spots, liver spots, sun damage,...