Matches 1 - 50 out of 263 1 2 3 4 5 6 >


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US20120251632 TREATMENT OF ACUTE EXACERBATION OF ASTHMA AND REDUCTION OF LIKELIHOOD OF HOSPITALIZATION OF PATIENTS SUFFERING THEREFROM  
The invention provides a method of improving one or more clinical outcomes of an individual experiencing an acute respiratory attack. The acute respiratory attack may include acute reversible...
US20110117213 TREATMENT OF ACUTE EXACERBATION OF ASTHMA AND REDUCTION OF LIKELIHOOD OF HOSPITALIZATION OF PATIENTS SUFFERING THEREFROM  
The invention provides a method of improving one or more clinical outcomes of an individual experiencing an acute respiratory attack. The acute respiratory attack may include acute reversible...
US20110053989 METHODS AND MATERIALS FOR TREATING ORTHOSTATIC HYPOTENSION OR POSTURAL TACHYCARDIA SYNDROME  
This document provides methods and materials related to treating orthostatic hypotension and/or postural tachycardia syndrome. For example, methods and materials for using a composition containing...
US20140296302 Methods For Treating Inflammation  
The present invention provides methods for treating or limiting development of inflammatory disorders.
US20140080874 Methods For Treating Inflammation  
The present invention provides methods for treating or limiting development of inflammatory disorders.
US20130017616 Methods For Treating Inflammation  
The present invention provides methods for treating or limiting development of inflammatory disorders.
US20150133408 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESTLESS LEG SYNDROME AND FIBROMYALGIA  
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical...
US20140171472 Pyridoxamine for the Treatment of Diabetic Kidney Disease  
The present invention provides pharmaceutical compositions comprising dosage units of pyridoxamine, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier, and...
US20130295074 Pyridoxamine for the Treatment of Diabetic Kidney Disease  
The present invention provides pharmaceutical compositions comprising dosage units of pyridoxamine, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier, and...
US20130011379 Pyridoxamine for the Treatment of Diabetic Kidney Disease  
The present invention provides pharmaceutical compositions comprising dosage units of pyridoxamine, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier, and...
US20110178139 Pyridoxamine for the Treatment of Diabetic Kidney Disease  
The present invention provides pharmaceutical compositions comprising dosage units of pyridoxamine, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier, and...
US20110281872 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CANCER  
The invention relates to compositions and methods for the treatment and prevention of cancer and other cell proliferative disorders.
US20140235637 COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS  
Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound,...
US20130102597 COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS  
Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound,...
US20130303568 Substituted 2-Aminoacetamides and the Use Thereof  
The invention is directed to substituted 2-aminoacetamides represented by formula (II): and to pharmaceutically acceptable salts and prodrugs thereof, wherein the substituents are defined herein....
US20150051233 METHODS AND COMPOSITIONS FOR TREATMENT OF FIBROSIS  
Embodiments of the invention include methods of treating, preventing, and/or reducing the risk of fibrosis in an individual in need thereof. In some embodiments, particular small molecules are...
US20150025068 BISARYLSULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION AND CANCER  
A compound of formula (I), useful for the treatment of cancer, inflammation and inflammatory disorders, and a pharmaceutical composition containing the compound.
US20140128393 Methods of Treating Cancer  
The present invention relates to methods of treating cancer by administering the EZH2 inhibitor compounds and pharmaceutical compositions to subjects in need thereof. The present invention also...
US20090264477 BETA ADRENERGIC RECEPTOR AGONISTS FOR TREATMENT OF PAIN AND/OR INFLAMMATION  
Effective treatments of pain and/or inflammation are provided. Through the administration of an effective amount of at least one beta adrenergic agonist at or near a target site, one can reduce,...
US20130310425 NOVEL POLYMORPH FORMS OF (2S)-(4E)-N-METHYL-5-[3-(5-ISOPROPOXYPYRIDIN)YL]-4-PENTEN-2-AMINE  
Polymorph forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2- amine p-hydroxybenzoate, and methods for their preparation, pharmaceutical composition containing said polymorph(s)...
US20150005328 Oximes For Treatment Of Peripheral And Central Nervous System Exposure to Acetyl Cholinesterase Inhibitors  
The present invention relates to non-charged oxime compounds which are acetyl cholinesterase (AChE) reactivators of inhibited AChE and which protect against organophosphate poisoning both...
US20130035351 Oximes For Treatment Of Peripheral And Central Nervous System Exposure To Acetyl Cholinesterase Inhibitors  
The present invention relates to non-charged oxime compounds which are acetyl cholinesterase (AChE) reactivators of inhibited AChE and which protect against organophosphate poisoning both...
US20120316138 PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF OBESITY AND OTHER METABOLIC DISEASES  
The present invention relates to thiazolidinedione analogues and pharmaceutical compositions that are useful for treating and/or preventing obesity or diabetes, optionally in combination with a...
US20110059905 METHODS OF TREATING DISEASE-INDUCED ATAXIA AND NON-ATAXIC IMBALANCE  
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic acetylcholine receptor activity.
US20120115849 Treatment of Addiction and Impulse-Control Disorders Using PDE7 Inhibitors  
This disclosure is directed to treatment of addictions and primary impulse-control disorders using phosphodiesterase 7 (PDE7) inhibitors, alone or in combination with other therapeutic agents.
US20120065198 Detection and Treatment of Schizophrenia  
The present invention provides a method for diagnosing schizophrenia, and a schizophrenia diagnostic reagent or device for use in the method. The present invention further provides a therapeutic...
US20110028470 Detection and Treatment of Schizophrenia  
The present invention provides a method for diagnosing schizophrenia, and a schizophrenia diagnostic reagent or device for use in the method. The present invention further provides a therapeutic...
US20100305056 CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASE  
Several parasites responsible for mammalian diseases are dependent on cysteine protease for various life-cycle functions. Inhibition or decreasing function of these proteases can be useful in the...
US20150258052 METHODS OF USING FEXARAMINE AND AGENTS THAT INCREASE SYMPATHETIC NERVOUS SYSTEM ACTIVITY TO PROMOTE BROWNING OF WHITE ADIPOSE TISSUE  
Provided are methods of promoting browning of white adipose tissue (WAT) in a subject. Such methods can include administering to a subject (e.g., via the gastrointestinal tract) a therapeutically...
US20140323473 COMPOUNDS AND METHODS TO TREAT ORGANOPHOSPHORUS POISONING  
Organophosphate (OP) nerve agents and pesticides are potent inhibitors of acetylcholinesterase (AChE). Though oxime nucleophiles can reactivate an AChE-phosphyl adduct, the adduct can undergo a...
US20140296303 Use of Pyridoxamine to Treat and/or Prevent Disease Processes  
Methods for treating and/or preventing at least one symptom of a disorder associated with oxidative stress, carbonyl stress, or combinations thereof in a subject. In some embodiments, the methods...
US20130065929 Use of Pyridoxamine to Treat and/or Prevent Disease Processes  
Methods for treating and/or preventing at least one symptom of a disorder associated with oxidative stress, carbonyl stress, or combinations thereof in a subject. In some embodiments, the methods...
US20140044806 NEW POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR  
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The...
US20140010898 New positive allosteric modulators of nicotinic acetylcholine receptor  
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The...
US20130012530 New Positive allosteric modulators of nicotinic acetylcholine receptor  
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The...
US20130310386 METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION  
Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a...
US20120101105 ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS  
The present invention relates to aryl substituted carboxamide derivatives of formula (I) or a pharmaceutically acceptable salt thereof, which have blocking activities of T-type calcium channels or...
US20090082407 Pyridoxamine for the Treatment of Diabetic Kidney Disease  
The present invention provides pharmaceutical compositions comprising dosage units of pyridoxamine, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier, and...
US20150157567 INHALATION COMPOSITIONS COMPRISING MUSCARINIC RECEPTOR ANTAGONIST  
The invention relates to pharmaceutical powder compositions administered by means of inhalers. More particularly, it relates to pharmaceutical powder compositions having the content uniformity and...
US20150208646 AQUEOUS SUSPOEMULSION CONTAINING LAMBDA-CYHALOTHRIN AND METHODS FOR MAKING AND USING THE SAME  
An aqueous suspoemulsion, characterized in that it contains at least the two components: (a) a dispersed oil phase comprising: (i) lambda-cyhalothrin as the first active ingredient, and(ii) at...
US20140323527 ARYLOXY AMINE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL MODULATORS  
The present invention relates generally to the field of therapeutic treatment and compounds having utility therefor, in particular the therapy or management of conditions associated with...
US20110021577 ARYLOXY AMINE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL MODULATORS  
The present invention relates generally to the field of therapeutic treatment and compounds having utility therefor, in particular the therapy or management of conditions associated with...
US20090088458 N-(Pyridin-4-Yl)-2-Phenylbutanamides as Androgen Receptor Modulators  
Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment...
US20140315913 SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS PDE4 INHIBITORS  
The invention provides a chemical entity of Formula (I) wherein R1, R2, R3, R4, Y and Z have any of the values described herein, and compositions comprising such chemical entities; methods of...
US20150183800 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO  
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the...
US20140178374 BAX AGONIST, COMPOSITIONS, AND METHODS RELATED THERETO  
The disclosure relates to BAX activators and therapeutic uses relates thereto. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer,...
US20140140932 Functionalized Magnetic Nanoparticles and Use in Imaging Amyloid Deposits and Neurofibrillary Tangles  
The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds to β-amyloid deposits and/or neurofibrillary tangles. The present disclosure...
US20150031714 METHODS AND COMPOSITIONS FOR PREVENTION OF ALLERGIC REACTION  
Embodiments of the invention include methods of preventing and/or reducing the risk or severity of an allergic reaction in an individual. In some embodiments, particular small molecules are...
US20080171767 Acetamide Compounds as Fungicides  
Compounds of the general formula (I); wherein the substituents are as defined in claim 1, are useful as fungicides.
US20150250805 COMPOUNDS FOR THE TREATMENT OF ADDICTION  
Disclosed are novel compounds having the structure of Formula (I): which are useful for treating mammals for dependence upon substances of addiction, for example addiction to a dopamine-producing...

Matches 1 - 50 out of 263 1 2 3 4 5 6 >