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US20120283204 TALARAZOLE METABOLITES  
Novel metabolites of talarazole of formula (I) have been isolated and characterized, wherein R═H, OH, OSO3H or O-gly; R1, ═H, OH, OSO3H, O-gly or =0; and gly=a glucuronate, or a pharmaceutically...
US20140047569 Methods of Treating Disorders Associated with Protein Aggregation  
The present invention relates to methods of treatment of clinical disorders associated with protein aggregation comprising administering, to a subject, an effective amount of an anti-protein...
US20130024953 Methods of Treating Disorders Associated with Protein Aggregation  
The present invention relates to methods of treatment of clinical disorders associated with protein aggregation comprising administering, to a subject, an effective amount of an anti-protein...
US20150182410 PNEUMATIC WRAP COMPRESSION TREATMENTS FOR VENOUS CONDITIONS  
A method of treatment of a condition such as deep vein thrombosis, arterial insufficiency, lymphedema, pulmonary embolism, and pain includes use of a pneumatic compression wrap, pump, and...
US20120295859 METHOD FOR TREATMENT OF MALARIA  
A method for treatment of malaria including administering to a patient in need thereof a flavonoid glycoside compound.
US20140186264 EXTRACELLULAR VESICLE-ASSOCIATED PROTEIN MARKERS OF CANCER  
Extracellular vesicle-associated protein biomarkers for use in diagnosing and staging carcinomas, e.g., lung and ovarian cancers.
US20110281808 Composition and Method for Increasing Pre Workout Thermogenics  
The present invention provides a composition for causing a simultaneous and synergistic increase in central nervous system activity and thermogenesis in a mammal, comprising Yerba Mate as a source...
US20140227284 SYNTHETIC LETHALITY AND THE TREATMENT OF CANCER  
Described herein are compounds, compositions and methods for treatment of cancer. Also described are methods and uses for identifying subject with cancer that are suitable for treatment with the...
US20150182544 Modified Saponins for the Treatment of Fungal Infections  
Methods of treating a fungal infection in a subject, the method comprising administering to the subject a modified saponin.
US20130018007 Modified Saponins for the Treatment of Fungal Infections  
Methods of treating a fungal infection in a subject, the method comprising administering to the subject a modified saponin.
US20120196818 METHOD FOR PREPARING POLYPHENOL EXTRACTS FROM SPINACH LEAVES  
A method for preparing a concentrated spinach extract in a liquid or dry form and having a polyphenol titer greater than or equal to 50% is described. The method includes a step of purifying a raw...
US20110144003 MAINTENANCE THERAPY REGIME/REGIMEN FOR THE TREATMENT OF ACNE  
A novel maintenance therapy regime/regimen for the treatment of acne related diseases includes administering an oral antibiotic with a topical fixed-dose combination of a retinoid, such as...
US20130079295 TREATMENT OF CARTILAGE RESORPTION  
Excessive articular cartilage degradation is treated or prevented by administration to a mammal such as a human Pueraria lobata (Kudzu) root or an extract thereof.
US20120115800 Pigment Aggregates  
The invention provides a method for in vitro formation of anthocyanic vacuolar inclusion (AVD-like structures, the method comprising the step of combining at least one anthocyanin, and b) at least...
US20110311651 CARDENOLIDES FOR THE TREATMENT OF OCULAR CANCER  
The instant invention provides methods of using a class of compounds known as cardenolides in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides...
US20140356340 EXTENSIONAL VISCOSITY TO PROMOTE SAFE SWALLOWING OF FOOD BOLUSES  
Nutritional products having improved cohesiveness of food boluses and methods of making and using same are provided. The nutritional products may include nutritional compositions and high...
US20140294787 EXTENSIONAL VISCOSITY TO PROMOTE SAFE SWALLOWING OF FOOD BOLUSES  
Nutritional products having improved cohesiveness of food boluses and methods of making and using same are provided. The nutritional products may include nutritional compositions and high...
US20110136751 Use of Polyphenols in the Treatment of Cancer  
The present invention relates to polyphenol compounds, compositions thereof, and methods for treating or preventing cancer in a subject, the methods comprising co-administering to a subject an...
US20140045777 METHOD OF INHIBITING PREMATURE AGING OF HUMAN SKIN CAUSED BY EXPOSURE TO INFRARED RADIATION  
A method of inhibiting premature aging of human skin caused by exposure to infrared radiation comprising contacting the skin with a composition containing a therapeutically-effective amount of at...
US20110076343 Multiple Myeloma Treatments  
Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided.
US20110059074 Knowledge-Based Proliferation Signatures and Methods of Use  
The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a...
US20130324487 Cyanidin-3-glucoside and Methods for Using the Same  
The present invention provides diet supplement compositions comprising cyanidin-3-glucoside (C3G) or C3G source or extracts and methods for using the same to aid in bodily fat loss.
US20130109628 MICRORNA COMPOSITIONS AND METHODS RELATED THERETO  
The disclosure relates to microRNAs (miRNAs) for the prophylaxis and/or treatment of neoplasia. The disclosure relates in particular to sequence corresponding to miR2 and the miR-548 family,...
US20130345151 PREPARATION FOR ORAL ADMINISTRATION COMPRISES QUERCETIN GLYCOSIDE AND A WATER BASED SOLVENT EXTRACT OF CARTILAGE CONTAINING CHONDROITIN SULFATE  
It is an object of the present invention to provide a preparation for oral administration in which the bitter taste derived from quercetin glycoside is improved. The bad taste derived from...
US20110124577 PREPARATION FOR ORAL ADMINISTRATION COMPRISES QUERCETIN GLYCOSIDE AND A WATER-BASED SOLVENT EXTRACT OF CARTILAGE CONTAINING CHONDROITIN SULFATE  
It is an object of the present invention to provide a preparation for oral administration in which the bitter taste derived from quercetin glycoside is improved. The bad taste derived from...
US20130338089 METHODS AND COMPOUNDS FOR MODULATING THE SECRETION OR EXPRESSION OF ADHESION PROTEINS OR ANGIOPOIETINS OF CELLS  
This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins, angiopoietins or their receptors to cure diseases, for...
US20110123488 Method of Treatment for Cancers Associated with Elevated HER2 Levels  
Novel methods of treating proliferative disorders characterized by elevated Her-2, and the patient is then administered an effective amount of an HSP90 inhibitor.
US20140011756 Method for Treatment of Inflammation  
A method of treating inflammation, an inflammatory condition, or AIDS-associated neurological disorder in a subject in need of such treatment is disclosed. The method includes administering to...
US20150086655 Morinda Citrifolia Juice Formulations Comprising Iridoids  
Embodiments of the invention relate to fortified food and dietary supplement products which may be administered to produce desirable physiological improvement. In particular, embodiments of the...
US20140154266 METHODS OF TREATING A METABOLIC SYNDROME BY MODULATING HEAT SHOCK PROTEIN (HSP) 90-BETA  
The invention provides methods of treatment of metabolic syndrome with HSP90 inhibitors, particularly HSP90β inhibitors. The invention provides methods of diagnosis and monitoring of metabolic...
US20120087980 STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES  
Flavonoid glycosides, such as isoquercitrin, are shown to stimulate the formation of neuritis and neuronal synapses in neurons and neuronal progenitor (stem) cells.
US20130165396 Apple Skin Extracts for Treating Cardiovascular Disease  
Pharmaceutical and nutraceutical compositions and methods for treating cardiovascular disease, comprising apple skin extracts which can reduce cholesterol levels and inhibit low density...
US20110082098 NOVOBIOCIN ANALOGUES AND TREATMENT OF POLYCYSTIC KIDNEY DISEASE  
Novobiocin analogues are useful in methods of treating, inhibiting, and/or preventing cyst formation in autosomal dominant polycystic kidney disease (ADPKD) in a subject. The disclosure provides...
US20140364382 COMPOSITION FOR INHIBITING LIVER FUNCTION DETERIORATION, CONTAINING CITRUS PEEL EXTRACT OR NARIRUTIN AS ACTIVE INGREDIENT, AND METHOD FOR EXTRACTING NARIRUTIN FROM CITRUS PEEL  
The present invention relates to a pharmaceutical composition for treating liver diseases, containing a narirutin extract of citrus peel extract or narirutin as an active ingredient. The extract...
US20120219581 METHODS AND FORMULATIONS FOR TREATING CHRONIC LIVER DISEASE  
An anti-inflammatory and anti-fibrotic antioxidant formulation for treatment of hepatic oxidative stress and cirrhosis is disclosed. The antioxidant formulation can further include at least one of...
US20130004482 Methods of Treating Breast Cancer with Anthracycline Therapy  
The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The...
US20140023615 THERMO-SENSITIVE, MUCOADHESIVE OR DERMOADHESIVE, AND PENETRATION-ENHANCING FORMULATIONS FOR TOPICAL DELIVERY OF THERAPEUTICS  
The present invention provides thermo-sensitive, mucoadhesive biopolymer formulations that enhance the penetration of therapeutics across the skin or mucosal surfaces. In a preferred embodiment,...
US20110191868 METHODS FOR IDENTIFICATION AND USE OF AGENTS TARGETING CANCER STEM CELLS  
The invention relates to methods for identifying compounds and compositions that target cancer stem cells. In some aspects, the invention relates to treatment methods that use compounds and...
US20130231297 DIETARY SUPPLEMENT FOR IMPROVING VISUAL PERFORMANCE  
An orally administered composition and method for improving visual performance using the composition is provided. The composition comprises a combination of astaxanthin, saffron, lutein,...
US20150017264 PROCASPASE 3 ACTIVATION BY COMBINATION THERAPY  
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the...
US20140128333 Compounds, Compositions, and Methods for Decreasing Intestinal Glucose Uptake and Inducing Incretin Release  
The present invention relates to methods for decreasing intestinal glucose uptake and inducing incretin release in a human subject, entailing the activation of human G protein-coupled receptor...
US20110183019 METHODS OF SCREENING FOR AND TREATING AUTISM SPECTRUM DISORDERS AND COMPOSITIONS FOR SAME  
Disclosed are methods of screening for an autism spectrum disorder, compositions that inhibit the release of molecules that disrupt the blood-brain barrier, compositions for treating autism...
US20110301106 Use of Icariside II in Manufacture of Products for Preventing or Treating Male or Female Sexual Dysfunction  
The present invention provides the use of icariside II or extract comprising thereof in manufacture of products for preventing or treating male or female sexual dysfunction, in particular, the use...
US20110014204 Cancer Chemoprevention Strategy Based on Loss of Imprinting of IGF2  
The present invention relates to targets of loss of imprinting (LOI) affected IGF2 gene products in pre-malignant tissues, where methods of inhibiting those targets, including IGFR1, are disclosed...
US20140148399 Compositions and methods for treating or ameliorating obesity or for reducing diabetic hypercholesterolemia  
Obesity is one of the major health concerns in the Twenty-First Century and is one of the leading causes of preventable death. It is a strong risk factor for Type 2 Diabetes. Disclosed herein are...
US20110223256 Method For Stabilizing Flavonoid Aqueous Dispersion  
A method for suspending microparticulated water insoluble bioactive compound in a beverage by incorporating solubilized or dispersed microparticulated compound and at least one dispersion...
US20150174188 METHODS FOR INHIBITING ADVANCED GLYCATION END PRODUCT PRODUCTION, INHIBITING FIBROBLAST APOPTOSIS, AND/OR PROMOTING HUMAN FIBROBLAST-COLLAGEN GRATING FORMULATION USING CHERRY BLOSSOM AND CHERRY LEAF EXTRACT  
Disclosed is an AGE production inhibitor or the like, which effectively inhibits the production of an advanced glycation end product (AGE), while having improved biological safety. Specifically...
US20110257117 OLIVE COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS  
A method of treating an inflammatory condition with a hydroxytyrosol-rich composition. Improvement is monitored as a reduction in the levels of a biochemical marker such as homocysteine or...
US20120094945 Discovery of Selective Glucocorticoid Receptor Modulators by Multiplexed Reporter Screening  
The invention relates to assays to detect selective gene regulation by ligand dependent transcription factors. The invention also relates to selective modulators of the glucocortocoid receptor for...
US20110189312 Compositions and Methods for Supporting Heat Shock Protein Function  
Compositions and methods for promoting or maintaining protein accretion in cells, particularly in skeletal muscle cells, by supporting heat shock protein function. The compositions comprise...