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US20080119485 |
Novel Benzofurans and Indols
Compounds of formula (I)
wherein X is a fluorine or a chlorine atom; the methyl groups located at the 2- and 5-position of the piperazine ring are in trans-configuration to each other; Y is NH...
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US20080108628 |
Indolylmaleimide derivatives
Provided are compounds of formula I
which have interesting pharmacological properties.
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US20080096877 |
Indole compound
The purpose of the present invention is to provide a glucokinase activator useful as a pharmaceutical agent such as an agent for the prophylaxis or treatment of diabetes, obesity and the like.
...
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US20080081810 |
OXINDOLE DERIVATIVES
There is provided compounds of the formula
wherein R 6 , V, W, X, Y, Q and n are as described. The compounds exhibit activity as anticancer agents.
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US20080076759 |
Therapeutic Heterocyclic Compounds 507
Provided herein is a compound having the formula (I):
Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized...
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US20080064684 |
1-Aryl- or 1-alkylsulfonyl-heterocyclybenzazoles as 5-hydroxytryptamine-6 ligands
The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor.
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US20080057124 |
Indolyl-3-glyoxylic acid derivatives having therapeutically valuable properties
The invention relates to the use of N-substituted indole-3-glyoxylamides of the general
and to pharmaceutical compositions having antitumor action.
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US20080051400 |
Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound
The present invention relates to methods useful for treating or preventing anemia or thrombocytopenia, comprising administrating an effective amount of a Triheterocyclic Compound to a subject in...
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US20080045543 |
Arylpiperazine derivatives and uses thereof
Compounds of the formula:
or pharmaceutically acceptable salts thereof, wherein m, n, X, Y, Z, Ar, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are defined herein. Also provided are...
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US20080039446 |
Substituted isoindoles and their use
The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I),
a method for the production of these compounds, pharmaceutical compositions containing them, and...
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US20080032968 |
New compounds
The present invention relates to novel compounds of formula (I):
wherein m, n, R 0 , R 1 , R 2 , R 3 and R 4 are as described herein,
to pharmaceutical compositions comprising the...
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US20080027074 |
2-(1H-Indolysulfanyl)-Aryl Amine Derivatives for Use in the Treatment of Affective Disorders, Pain, Adhd and Stress Urinary Incontinence
The present invention relates to aniline derivatives of the general formula I as the free base or salts thereof and their use.
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US20080009485 |
Methods for the use of inhibitors of cytosolic phospholipase A2 in the treatment of thrombosis
This invention provides methods for the use of substituted indole compounds of the general formula:
and pharmaceutically acceptable salt forms thereof. The invention provides methods for the...
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