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US20110280893 |
SYNTHETIC LIPID A DERIVATIVE
The invention provides functionalized monosaccharides and disaccharides suitable for use in synthesizing a lipid A derivative, as well as methods for synthesizing and using a synthetic lipid A...
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US20110002989 |
METHODS, DOSAGE FORMS AND KITS FOR ADMINISTERING ZIPRASIDONE WITHOUT FOOD
The present invention provides methods, dosage forms and kits for treating with an effective amount of ziprasidone a CNS disorder in a human when the human is in a fasted state. In one embodiment,...
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US20100310602 |
SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS
Compounds, particularly, glucopyranosyl lipid adjuvant (GLA) compounds, having the following structure (I) are provided: or a pharmaceutically acceptable salt thereof, wherein L1, L2, L3, L4, L5,...
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US20110098238 |
ELUCIDATING LIGAND-BINDING INFORMATION BASED ON PROTEIN TEMPLATES
A method, computer-readable medium, and system for identifying compounds from chemical libraries that can be used for the therapeutic treatment of a disease or used as lead compounds in a drug...
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US20100331268 |
Nitrated Lipids and Methods of Making and Using Thereof
Described herein are nitrated lipids and methods of making and using the nitrated lipids.
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US20110195128 |
TREATING OR PREVENTING GOUT
Use of glycomacropeptide to treat or prevent gout, use of one or more phospholipids and one or more gangliosides to treat or prevent gout, or use of glycomacropeptide and one or more phospholipids...
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US20110311476 |
Methods For Treating An Immune Deficiency Or Enhancing Immune Function Using Salicinium, Non-Limited In Terms Of Treatment Indication, But Encompassing Methods For Treating Cancer And Microbial, Bacterial, Viral, Fungal; Non-Limited In Terms of Delivery Mode, Formulation
The present invention provides novel immunotherapeutic compositions and methods useful for treating or preventing microbial infections, weakened immune systems, diseases in which cells have become...
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US20110009351 |
SCREENING ASSAY TO IDENTIFY CORRECTORS OF PROTEIN TRAFFICKING DEFECTS
The present invention relates to a novel assay or screen for identifying compounds with potential therapeutic value for the treatment of protein trafficking diseases such as Cystic Fibrosis (CF)...
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US20100317603 |
Treatment of Cancer and Inflammatory Disorder
Disclosed are extracts, compositions, and methods for treating cancer and inflammatory disorders. Also disclosed are methods for preparing extracts or compounds for treating the disorders.
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US20110144041 |
Methods for Treating Inflammatory Bowel Disease
A method is described for treating inflammatory bowel disease in a subject in need thereof. The method comprises administering a formulation comprising at least one ganglioside to the subject,...
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US20110207680 |
Administration of Glufosfamide For The Treatment of Cancer
Administration of Glufosfamide alone and in combination with another anticancer agent is useful for the treatment of gall bladder cancer.
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US20110301105 |
COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS
We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells...
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US20120058895 |
COMPOSITIONS AND METHODS FOR CONTROLLING PESTS WITH GLYCOLIPIDS
Biosurfactants produced by microbes are used to control pests. The biosurfactants can be produced by cultivating a biosurfactant-producing microbe, producing a fermentation broth, and obtaining the...
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US20120100231 |
Antimicrobial Compositions And Methods Of Making And Using The Same
Antimicrobial (e.g., moldicide, fungicide, bacteriacide, and virucide) compositions are disclosed. Methods of making and using antimicrobial (e.g., moldicide, fungicide, bacteriacide, and virucide)...
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US20120087980 |
STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES
Flavonoid glycosides, such as isoquercitrin, are shown to stimulate the formation of neuritis and neuronal synapses in neurons and neuronal progenitor (stem) cells.
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US20110182960 |
Antimicrobial Coating
The invention relates to methods for applying coatings comprising recombinant gelatin and an antimicrobial agent to a surface. In particular, the invention is concerned with methods for coating...
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US20110118197 |
PREVENTION OF HEPATIC ISCHEMIC REPERFUSION INJURY BY ADMINISTRATION OF SULFATIDES
Hepatic ischemic reperfusion injury is a major complication of liver transplantation, resectional hepatic surgeries, trauma surgery and shock. Disclosed herein are methods for the prevention and...
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US20050037100 |
Utilization of extracts from iris plants, cimicifuga racemose and tectorigenin as an estrogen-like organ-selective medicament without uterotropic
The present invention relates to the use of extracts from Iridaceae and from Cimicifuga racemosa, and of tectorigenin as an estrogen-type, organoselective medicament for the selective treatment...
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US20120035120 |
GLYCOLIPIDS AS TREATMENT FOR DISEASE
This invention provides compounds, compositions, and methods for treating a disorder selected from cancer, hyperinsulinemia, hypoglycemia, hyperinsulinemia with hypoglycemia, atypical Parkinson's...
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US20110191868 |
METHODS FOR IDENTIFICATION AND USE OF AGENTS TARGETING CANCER STEM CELLS
The invention relates to methods for identifying compounds and compositions that target cancer stem cells. In some aspects, the invention relates to treatment methods that use compounds and...
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US20120071426 |
METHODS AND COMPOSITIONS FOR TREATING LUNG CANCER
The present invention provides methods and compositions for treating lung cancer by cyclohexenone compounds.
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US20110257113 |
Method for Inducing a Trif-Bias
The use of a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to...
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US20110257115 |
METHOD FOR TREATING RHINITIS AND SINUSITIS BY RHAMNOLIPIDS
The present invention is directed to methods for treating rhinitis or sinusitis in a subject. In one embodiment, the method comprises the steps of: identifying a subject in need thereof, and...
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US20110257109 |
USE OF DRUGS THAT ACTIVATE P2Y RECEPTORS TO ENHANCE SYNAPTOGENESIS
The present invention encompasses compositions and methods that activate P2Y receptors for the increased production of new synapses in the central nervous system. The formulations of the invention...
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US20120128798 |
Method of Treating Neurological Conditions with Extract of Nerium Species or Thevetia Species
A method of treating neurological condition in a subject by administration of an extract, or fraction or sub-fraction thereof, of Nerium species or Thevetia species is provided, wherein the...
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US20120065152 |
PRODRUGS OF GUANFACINE
Prodrugs of guanfacine, pharmaceutical compositions containing such prodrugs and a method for providing therapeutic benefit in the treatment of ADHD/ODD (attention deficient hyperactivity disorder...
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US20110237531 |
METHOD FOR PRODUCING SOPHOROSE LIPID
The present invention provides a low-cost, efficient method for producing a glycolipid biosurfactant, in particular, lactonic sophorose lipids. This method is characterized by culturing a...
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US20110206613 |
METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT
Biologically active compounds are provided that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer, infections and other hyperproliferative...
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US20120064044 |
METHODS OF TREATING EDEMA RELATED TO ISCHEMIA-REPERFUSION
Methods are described for preventing or reducing edema related to ischemia-reperfusion by treating the organ or tissue being transplanted with an aminoalkyl glucosaminide phosphate.
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US20100317604 |
FORSYTHIASIDE INJECTION PREPARATION AND PREPARATIVE METHOD THEREOF
The present invention discloses a Forsythiaside injection preparation and preparative method thereof. This injection preparation is prepared by Forsythiaside and pharmaceutical adjuvant.
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US20100311649 |
SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS
Certain novel substituted imidazole 4-carboxamides are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R). They...
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US20110003001 |
BISMUTH-THIOLS AS ANTISEPTICS FOR EPITHELIAL TISSUES, ACUTE AND CHRONIC WOUNDS, BACTERIAL BIOFILMS AND OTHER INDICATIONS
Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating acute wounds, chronic wounds and/or a wound or epithelial tissue surface that contains...
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US20110065662 |
Compounds, Compositions, and Methods for Protecting Brain Health in Neurodegenerative Disorders
Aspects of the invention relate to compounds, extracts and compositions thereof, and methods of using of the same, to treat neurodegenerative disorders and/or improve brain health. In certain...
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US20120084871 |
NPC1L1 ORTHOLOGUES
The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
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US20110124587 |
Pure Rebaudioside A
The invention provides a high throughput, high purity, high yield system and method of isolating and purifying rebaudioside A (“Reb A”), with acceptable water solubility for all commercial use...
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US20110028407 |
ENHANCEMENT OF INNATE RESISTANCE TO INFECTION
The present invention provides compounds and compositions that enhance the innate immune system. The present invention comprises methods of preventing, treating or ameliorating an infectious...
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US20110182909 |
Glufosfamide combination therapy
Glufosfamide administered in combination with other chemotherapeutic agents is useful in cancer treatment.
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US20110028413 |
Methods of Reducing Methotrexate Nephrotoxicity
The present invention provides compositions and methods to reduce renal damage caused by nephrotoxic drugs such as methotrexate. The invention provides compositions comprising a substituted...
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US20080027009 |
Surfactant Preparation Having Reduced Enzyme Damaging
A method of protecting skin enzymes from the harmful effects of a cosmetic cleansing preparation which comprises water and one or more anionic surfactants. The method comprises using a cleansing...
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US20100310487 |
ACTIVE INGREDIENT COMBINATION AND USE THEREOF
An active ingredient combination which comprises a) glycerol monoalkyl ether, b) bispyridinium alkane, c) polyol and d) antioxidant. The combination is advantageously used for producing a...
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US20120058087 |
DIAGNOSIS OF ENDOMETRITIS
The present invention relates to methods for diagnosing and treatment of a dormant infection of at least one pathogen. The invention further relates to a composition comprising an anti-dormancy...
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US20110070269 |
LIPOPOLYSACCHARIDE ISOLATED FROM PYRULARIA TISSUE AND/OR PYRULARIA-ASSOCIATED BACTERIA AND USES THEREOF
This disclosure provides, in certain embodiments, methods for generating and using extracts of Pyrularia (e.g., Pyrularia pubera) and/or epiphytic/endophytic bacteria associated therewith, either...
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US20110190225 |
Topical method for prompt relief of severe ascites
A means is provided to make the capsules of cirrhotic or fibrotic livers relatively impermeable to liver tissue fluid or lymph in humans or other mammals suffering from severe chronic ascites or...
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US20110306569 |
RHAMNOLIPID BIOSURFACTANT FROM PSEUDOMONAS AERUGINOSA STRAIN NY3 AND METHODS OF USE
The present disclosure relates to an isolated strain of Pseudomonas aeruginosa strain NY3 and compounds produced by this strain having biosurfactant activity, for instance rhamnolipids Rha-C8-C8:1,...
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US20120108528 |
NEW THERAPEUTIC APPROACHES FOR TREATING NEUROINFLAMMATORY CONDITIONS
The present invention relates to novel compositions which can be used for the treatment of neuroinflammation, in particular in subjects having a neurodegenerative, autoimmune, infectious, toxic or...
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US20110177085 |
Bitter Taste Receptors
The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or...
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US20110206743 |
NUTRITIONAL COMPOSITIONS WITH LIPID GLOBULES WITH A CORE COMPRISING VEGETABLE LIPIDS AND A COATING COMPRISING PHOSPHOLIPIDS OR POLAR LIPIDS
The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a large lipid globule size. The composition can be used to prevent...
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US20070141182 |
Combination of multiple nonteroidal antiinflammatory drugs and muscle relaxants for local treatment of musculoskeletal pain
This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation and the treatment of muscle spasms and associated pain, soreness and tightness of muscles in...
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US20110059909 |
METHODS FOR TREATING INFLAMMATORY DISORDERS
The present invention relates generally to the fields of molecular biology. More particularly, it concerns materials and methods for the treatment of nitric oxide and cytokind mediated disorders....
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US20110207681 |
USE OF GLUCOSYLGLYCEROL
The invention relates to the use of glucosylglycerol or glucosylglycerol esters with a view to increasing the expression of cell protective enzymes for the protection and stabilization of human...
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