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US20140243263 METHOD OF ENHANCING DIABETES RESOLUTION  
Disclosed are compositions and methods for increasing diabetes resolution in a diabetic patient having undergone gastric restrictive surgery, entailing use of active agent that produces an...
US20100317576 METHODS OF ENHANCING DIABETES RESOLUTION  
Disclosed are compositions and methods for increasing diabetes resolution in a diabetic patient having undergone gastric restrictive surgery, entailing use of active agent that produces an...
US20140056998 SYSTEM AND METHOD FOR DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS  
An assay for a GCH1 allele and associated genotype for the screening, prediction, diagnosis, prognosis, treatment and treatment response of psychiatric, neuropsychiatric, and neurological...
US20140121191 Oral Energy Supplement and Related Methods  
The present invention relates to oral dosage formulations consisting of at least one active ingredient contained in a plurality of hydrophobic carriers dispersed in an aqueous medium comprising a...
US20140314673 TREATMENT OF CANCER WITH DIHYDROPYRAZINO-PYRAZINES  
Provided herein are methods for treating or preventing head and neck squamous cell carcinoma characterized by deletion of chromosome 11q22 or loss of ataxia telangiectasia mutated expression,...
US20120035182 METHODS OF TREATMENT OF CHRONIC PAIN USING ESZOPICLONE  
The invention relates to the use of eszopiclone for the treatment of low-level, chronic pain and fatigue associated with pain.
US20120251495 PTERIN BASED THERAPIES FOR INFLAMMATORY CONDITIONS  
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection based upon the administration of calcium pterin. In one...
US20130158023 IDENTIFICATION OF GENE EXPRESSION AS A PREDICTIVE BIOMARKER FOR LKB1 STATUS  
Provided herein are methods for predicting the LKB1 status of a patient or a biological sample, comprising the measurement of particular gene expression levels relative to a set of reference levels...
US20130210829 APPLICATION OF 5-HT6 RECEPTOR ANTAGONISTS FOR THE ALLEVIATION OF COGNITIVE DEFICITS OF DOWN SYNDROME  
Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT6) receptor antagonists are...
US20140315907 TREATMENT OF CANCER WITH DIHYDROPYRAZINO-PYRAZINES  
Provided herein are methods for treating or preventing chronic lymphocytic leukemia, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound to a patient having chronic...
US20120263779 BIODEGRADABLE DRUG DELIVERY SYSTEM  
A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented...
US20140073632 TREATING PROTEIN FOLDING DISORDERS WITH SMALL MOLECULE CFTR CORRECTORS  
Novel CFTR corrector compounds that are effective in rescuing halide efflux in a cell are provided. Also provided are methods for treating protein folding disorders (e.g., cystic fibrosis). The...
US20140314674 TREATMENT OF CANCER WITH DIHYDROPYRAZINO-PYRAZINES  
Provided herein are methods for treating or preventing glioblastoma multiforme (GBM) characterized by O6-methylguanine-DNA methyltransferase (MGMT) expression and/or promoter methylation status,...
US20140256735 METHOD FOR ASSESSING A LIVER OF A PATIENT HAVING A CHRONIC HEPATITIS B VIRUS INFECTION  
The invention generally relates to method for assessing a liver of a patient having a chronic hepatitis B virus infection. In certain aspects, methods of the invention involve obtaining a sample...
US20120184556 SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS  
Disclosed are substituted benzoimidazolesulfonamides and substituted indolesulfonamides as mGluR4 potentiators.
US20130345164 TREATMENTS FOR CELLULAR PROLIFERATIVE DISORDERS AND IDENTIFICATION THEREOF  
This invention concerns methods of identifying treatments for treating various disorders and related computer products and systems. Also disclosed are methods for treating cellular proliferative...
US20130197002 BRIMONIDINE FOR TREATING VISUAL DISORDERS MEDIATED BY CENTRAL VISUAL PROJECTIONS FROM THE EYE  
The present invention relates to a method for treating visual disorders mediated by lateral geniculate nucleus, superior colliculus and the visual cortex by administering to a patient in need of...
US20110046136 METHODS FOR THE PRODUCTION OF FUNCTIONAL PROTEIN FROM DNA HAVING A NONSENSE MUTATION AND THE TREATMENT OF DISORDERS ASSOCICATED THEREWITH  
The present invention relates to functional proteins encoded by nucleic acid sequences comprising a nonsense mutation. The present invention also relates to methods for the production of functional...
US20120115839 USE OF SELECTIVE GABA A ALPHA 5 NEGATIVE ALLOSTERIC MODULATORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS  
The present invention relates to the pharmaceutical use of selective GABA A α5 negative allosteric modulators for the treatment, prevention and/or delay of progression of central nervous system ...
US20110002918 METHODS OF TREATING DISEASED TISSUE  
Treatment protocols for severe psoriasis include administering biologics, stopping all administration of the biologics after the severity of the psoriasis has reduced and has reached an...
US20140107568 METHOD OF DETERMINING AN INJECTED DOSE BASED ON A KNOWN ORAL DOSE  
The present disclosure relates to methods of determining dosages of compositions used in injection devices, in view of known oral doses of the same compositions.
US20120295864 METHOD FOR TREATING ACUTE MYELOID LEUKEMIA  
The present invention relates to the use of BI 6727 or a salt thereof or the hydrate thereof for treating patients suffering from acute myeloid leukemia (AML) comprising the administration of a...
US20110293740 TREATMENT SYSTEM AND METHOD FOR OSTEOPENIA AND OSTEOPOROSIS USING NON-SYNTHETIC BIO-AVAILABLE COMPOUNDS  
A treatment system and method for osteopenia and osteoporosis using non-synthetic bio-available hormones, vitamins, minerals, and agents may be customized by varying the dosage and formulation of...
US20110003822 P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN  
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or...
US20130178477 METHODS OF TREATING DIABETIC NEUROPATHY USING BENZENESULFONAMIDES  
This invention is directed to methods of treating diabetic neuropathy, particularly, diabetic peripheral neuropathy, in a patient in need of treatment thereof.
US20130336969 USE OF OLFACTOMEDIN-4 PROTEIN (OLFM4) IN COLORECTAL CANCER DIAGNOSIS  
The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting...
US20140227284 SYNTHETIC LETHALITY AND THE TREATMENT OF CANCER  
Described herein are compounds, compositions and methods for treatment of cancer. Also described are methods and uses for identifying subject with cancer that are suitable for treatment with the...
US20140315900 METHODS FOR TREATING CANCER USING DIHYDROPYRAZINO-PYRAZINE COMPOUND COMBINATION THERAPY  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound and an effective amount of an androgen receptor...
US20140162964 USE IN BRAIN DEGENERATIVE DISEASES  
Disclosed is a new use for sphingosine-1-phosphate (S1P) receptor agonists in the treatment of progressive dementia or brain degenerative diseases.
US20140011812 Methods of Treating Inflammation  
The present invention relates to methods of decreasing inflammation by inhibiting polo-like kinase (PlK)
US20120302572 USE OF EMT GENE SIGNATURES IN CANCER DRUG DISCOVERY, DIAGNOSTICS, AND TREATMENT  
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase...
US20120277180 Cofactors and Methods for Use for Individuals  
Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of...
US20140303120 METHODS FOR THE TREATMENT OF CANCER  
The present invention is directed to methods for treating cancer in a subject, such as a cancer of the endocrine system. In some aspects, the method includes administering to the subject one or...
US20120058097 COMPOSITIONS INCLUDING A SODIUM CHANNEL BLOCKER AND A B VITAMIN MOLECULE AND METHODS OF USE THEREOF  
The invention generally relates to compositions including a sodium channel blocker and a B vitamin molecule and methods of use thereof. In certain embodiments, the invention provides compositions...
US20130267522 METHODS FOR TREATING CANCER  
The invention relates to methods and uses for the treatment of a cancer. In particular, the invention relates to the use of a folate-vinca conjugate to treat urinary bladder cancer (e.g., invasive...
US20110003748 Method of treatment and compositions of D-chiro inositol and phosphates thereof  
The present invention relates to the use of D-chiroinositol or a phosphate thereof in combination with folate for the reduction or prevention of congenital deformations such as anorectal...
US20120321552 Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin  
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20110104050 Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin  
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20120196847 6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors  
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment...
US20110136751 Use of Polyphenols in the Treatment of Cancer  
The present invention relates to polyphenol compounds, compositions thereof, and methods for treating or preventing cancer in a subject, the methods comprising co-administering to a subject an...
US20130018040 Compositions And Methods For Treating Toxoplasmosis, Cryptosporidiosis, And Other Apicomplexan Protozoan Related Diseases  
Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the...
US20140235604 COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS  
A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically...
US20120295895 COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS  
A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically...
US20110112058 NOVEL MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL AND METHODS FOR TREATMENT OF NON-SMALL CELL LUNG CANCER  
Disclosed are novel calcium release-activated calcium (CRAC) channel inhibitors, methods for preparing them, pharmaceutical compositions containing them, and methods of treatment using them. The...
US20130197004 Optically Pure Diastereomers of 10-Propargyl-10-Deazaaminopterin and Methods of Using Same for the treatment of cancer  
The present invention relates to diastereomers of 10-propargyl-10-deazaminopterin, compositions comprising optically pure diastereomers of 10-propargyl-10-deazaminopterin, in particular the two...
US20130210826 METHODS FOR TREATING PAIN  
The present invention features methods and compositions for preventing, reducing, or treating a traumatic, metabolic, or toxic peripheral nerve lesion or pain including neuropathic pain,...
US20120321596 KIT FOR ADHERING BIOLOGICAL HARD TISSUES  
A kit for bonding to biological hard tissues, containing a phosphorylated polysaccharide, a polyvalent metal salt other than phosphates, and a solvent. The adhesive composition for biological hard...
US20130143891 Methods for Treating Methotrexate-Resistant Disorders with 10-Propargyl-10-Deazaaminopterin  
The present invention relates to a method for treating a methotrexate-resistant disorder in an individual, wherein the method comprises administering to the individual an effective amount of...
US20140011811 MYOSIN BINDING PROTEIN-C FOR USE IN METHODS RELATING TO DIASTOLIC HEART FAILURE  
The invention provides methods relating to the diagnosis and treatment of diastolic heart failure, kits for diagnosing diastolic heart failure or diastolic dysfunction, and related systems,...
US20130252960 PTERIDINES AND THEIR USE AS AGROCHEMICALS  
The present disclosure relates to 1- or 2-(4-(aryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and 1- or 2-(4-(heteroaryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and their use...