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US20100317576 |
METHODS OF ENHANCING DIABETES RESOLUTION
Disclosed are compositions and methods for increasing diabetes resolution in a diabetic patient having undergone gastric restrictive surgery, entailing use of active agent that produces an...
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US20120035182 |
METHODS OF TREATMENT OF CHRONIC PAIN USING ESZOPICLONE
The invention relates to the use of eszopiclone for the treatment of low-level, chronic pain and fatigue associated with pain.
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US20120251495 |
PTERIN BASED THERAPIES FOR INFLAMMATORY CONDITIONS
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection based upon the administration of calcium pterin. In one...
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US20120263779 |
BIODEGRADABLE DRUG DELIVERY SYSTEM
A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented...
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US20120184556 |
SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS
Disclosed are substituted benzoimidazolesulfonamides and substituted indolesulfonamides as mGluR4 potentiators.
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US20110046136 |
METHODS FOR THE PRODUCTION OF FUNCTIONAL PROTEIN FROM DNA HAVING A NONSENSE MUTATION AND THE TREATMENT OF DISORDERS ASSOCICATED THEREWITH
The present invention relates to functional proteins encoded by nucleic acid sequences comprising a nonsense mutation. The present invention also relates to methods for the production of functional...
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US20120115839 |
USE OF SELECTIVE GABA A ALPHA 5 NEGATIVE ALLOSTERIC MODULATORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS
The present invention relates to the pharmaceutical use of selective GABA A α5 negative allosteric modulators for the treatment, prevention and/or delay of progression of central nervous system ...
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US20110002918 |
METHODS OF TREATING DISEASED TISSUE
Treatment protocols for severe psoriasis include administering biologics, stopping all administration of the biologics after the severity of the psoriasis has reduced and has reached an...
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US20120295864 |
METHOD FOR TREATING ACUTE MYELOID LEUKEMIA
The present invention relates to the use of BI 6727 or a salt thereof or the hydrate thereof for treating patients suffering from acute myeloid leukemia (AML) comprising the administration of a...
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US20110293740 |
TREATMENT SYSTEM AND METHOD FOR OSTEOPENIA AND OSTEOPOROSIS USING NON-SYNTHETIC BIO-AVAILABLE COMPOUNDS
A treatment system and method for osteopenia and osteoporosis using non-synthetic bio-available hormones, vitamins, minerals, and agents may be customized by varying the dosage and formulation of...
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US20110003822 |
P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or...
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US20120302572 |
USE OF EMT GENE SIGNATURES IN CANCER DRUG DISCOVERY, DIAGNOSTICS, AND TREATMENT
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase...
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US20120277180 |
Cofactors and Methods for Use for Individuals
Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of...
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US20120058097 |
COMPOSITIONS INCLUDING A SODIUM CHANNEL BLOCKER AND A B VITAMIN MOLECULE AND METHODS OF USE THEREOF
The invention generally relates to compositions including a sodium channel blocker and a B vitamin molecule and methods of use thereof. In certain embodiments, the invention provides compositions...
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US20110003748 |
Method of treatment and compositions of D-chiro inositol and phosphates thereof
The present invention relates to the use of D-chiroinositol or a phosphate thereof in combination with folate for the reduction or prevention of congenital deformations such as anorectal...
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US20120321552 |
Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
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US20110104050 |
Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
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US20120196847 |
6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment...
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US20110136751 |
Use of Polyphenols in the Treatment of Cancer
The present invention relates to polyphenol compounds, compositions thereof, and methods for treating or preventing cancer in a subject, the methods comprising co-administering to a subject an...
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US20130018040 |
Compositions And Methods For Treating Toxoplasmosis, Cryptosporidiosis, And Other Apicomplexan Protozoan Related Diseases
Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the...
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US20120295895 |
COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS
A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically...
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US20110112058 |
NOVEL MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL AND METHODS FOR TREATMENT OF NON-SMALL CELL LUNG CANCER
Disclosed are novel calcium release-activated calcium (CRAC) channel inhibitors, methods for preparing them, pharmaceutical compositions containing them, and methods of treatment using them. The...
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US20120321596 |
KIT FOR ADHERING BIOLOGICAL HARD TISSUES
A kit for bonding to biological hard tissues, containing a phosphorylated polysaccharide, a polyvalent metal salt other than phosphates, and a solvent. The adhesive composition for biological hard...
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US20110301125 |
Method for Treating Macular Degeneration
Provided herein are novel and useful methods for preventing, treating, or ameliorating a macular degeneration such as dry macular degeneration, wet macular degeneration and age related macular...
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US20120213772 |
Metabolic biomarkers of Crohn's Disease
The invention provides for a method for identifying a biomarker in a fecal sample of a subject in need of such identification comprising: determining whether a fecal sample collected from a subject...
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US20110123488 |
Method of Treatment for Cancers Associated with Elevated HER2 Levels
Novel methods of treating proliferative disorders characterized by elevated Her-2, and the patient is then administered an effective amount of an HSP90 inhibitor.
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US20110217297 |
METHODS FOR CLASSIFYING AND TREATING BREAST CANCERS
The present invention relates to methods of treating a breast cancer in a subject, methods of identifying a subject with a breast cancer as a candidate for a therapy having efficacy for treating a...
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US20110224128 |
METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY
The invention features methods, compositions, and kits useful for the treatment of muscular dystrophy, e.g., Duchenne muscular dystrophy, in a patient.
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US20110301105 |
COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS
We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells...
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US20130065903 |
Method of Improving Diastolic Dysfunction
A method of treating, preventing, reversing, or ameliorating diastolic dysfunction includes reducing S-glutathionylated myosin binding protein-C (MyBP-C) level by administering to a host in need...
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US20110118267 |
Method and Kit for Treating or Preventing Psoriasis
Methods and kits for treating or preventing psoriasis or a symptom associated with psoriasis in a subject are described. The methods involve topical applications to the subject a therapeutically...
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US20110256237 |
METHODS AND COMPOSITIONS FOR TREATING ACNE VULGARIS AND ACNE ROSACEA
Methods and compositions are described for treating acne vulgaris and acne rosacea by administering compositions suitable for oral administration. Suitable compositions contain high dosages of the...
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US20110207737 |
SUBSTITUTED BICYCLIC AMINES FOR THE TREATMENT OF DIABETES
Described herein are substituted bicyclic amines. In particular, described herein are substituted bicyclic amines that are effective as antagonists of SSTR5 and useful for the treatment, control or...
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US20110318351 |
NOVEL METHODS OF CANCER DIAGNOSIS AND THERAPY TARGETED AGAINST A CANCER STEM LINE
Improved methods for treatment of cancer which involve the targeting of slow-growing, relatively mutationally-spared cancer stem line are provided. These methods are an improvement over previous...
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US20110319356 |
Methods Of Treating Optic Disorders
The present invention relates to methods for treating optic disorders or for reducing or alleviating the signs, symptoms, or pathological conditions related to such optic disorders. In particular,...
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US20110152272 |
Treatment Of Incontinence
The present invention relates to the use of agonists of 5-HT2C receptors for the treatment of urinary incontinence, preferably mixed incontinence or stress urinary incontinence. The invention also...
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US20120225854 |
COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES
The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates...
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US20120100223 |
LIPID-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF
Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed around and including the...
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US20130035304 |
SMALL MOLECULES FOR THE MODULATION OF MCL-1 AND METHODS OF MODULATING CELL DEATH, CELL DIVISION, CELL DIFFERENTIATION AND METHODS OF TREATING DISORDERS
This invention relates to compounds which selectively bind to the survival protein MCL-1 with high affinity and selectivity, pharmaceutical compositions containing such compounds and the use of...
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US20110071102 |
Compositions and Methods to Treat Recurrent Medical Conditions
The invention describes methods and compositions for alleviating recurrent medical afflictions for which anxiety may cause or exacerbate the affliction. A subject suffering from the affliction is...
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US20110301144 |
Kinase Antagonists
The present invention provides novel compounds that are antagonists of PI3 kinase, PI3 kinase and tyrosine kinase, PI3 kinase and mTOR, or PI33 kinase, mTOR and tyrosine kinase.
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US20130004482 |
Methods of Treating Breast Cancer with Anthracycline Therapy
The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The...
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US20130071489 |
METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an...
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US20120214816 |
METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an...
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US20110286944 |
METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an...
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US20100297037 |
MATERIAL COMPOSITION FOR ORAL HYGIENE PRODUCT
The present invention relates to a material composition, particularly for an oral hygiene product suitable for combating caries and also for combating parodontitis and gingivitis. Said material...
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US20110236466 |
CHEMO VECTOR THERAPY TO DELIVER CHEMOTHERAPY MOLECULES TO SPECIFIC CELLS TO MANAGE BREAST CANCER, OTHER CANCERS AND INFLAMMATORY DISORDERS
The innovative treatment strategy described here utilizes configurable microscopic medical payload delivery devices to act as a transport means to deliver chemotherapy molecules to specific cell...
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US20110311648 |
Novel Methods for the Treatment of Cancer
Compositions and methods for the treatment of malignancy and chronic viral infection are disclosed.
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US20110046144 |
IMIDAZOPYRAZINOL DERIVATIVES FOR THE TREATMENT OF CANCERS
Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-IR enzyme and are useful for the...
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US20110020270 |
TREATMENT AND PROPHYLAXIS
This invention discloses the use of an E-selectin antagonist and a mobilizer of hematopoietic stem cells or progenitor cells in methods and compositions for treating or preventing immunocompromised...
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