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US20080108595 |
INHIBITORS OF CATHEPSIN S
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at...
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US20080090825 |
Metallo-beta-lactamase inhibitors
A new metallo-β-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of β-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid...
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US20080085891 |
Asthma and allergic inflammation modulators
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides...
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US20080058333 |
CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS
Cycloalkyl ketoamide derivatives, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such cycloalkyl ketoamide derivatives as...
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US20080045533 |
Novel cyclohexyl sulphones
Novel sulphones of formula I are disclosed:
The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of...
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US20080039320 |
Use Of Menadione
The use of menadione or one of its plant-compatible acid addition salts for enhancing the activity of agrochemicals against phytopathogenic fungi, mixtures of menadione and at least one active...
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US20080032981 |
ARYL N-CYANOGUANIDINES AND METHODS RELATED THERETO
Compounds, compositions and methods treating arthritic disorders such as osteoarthritis or rheumatoid arthritis, and for treating other diseases associated with altered mitochondrial function, such...
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US20080032978 |
SOLUBLE EPOXIDE HYDROLASE INHIBITORS
Disclosed are urea and thiourea compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with...
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US20080015190 |
Inhibitors of Histone Deacetylase
The present invention relates to hydroxamic acid derivatives that are inhibitors of histone deacetylase (HDAC). The compounds of the present invention are useful for treating cellular proliferative...
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US20080003214 |
Medicaments Comprising Carbonyl Compounds, And The Use Thereof
Use of compounds of the formula (I) in which D, E, G, W, X, Y, T, R 1 and R 2 have the meaning indicated in Patent Claim 1 , for the prophylaxis and/or therapy of thromboembolic diseases
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