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US20110046120 TREATMENT OF IMPULSE CONTROL DISORDERS  
The present disclosure provides methods and compositions for treating Impulse Control disorders including, for example, pathological gambling using α2-adrenergic agonists, β-adrenergic receptor...
US20100310622 DRY EYE TREATMENT BY PUNCTA PLUGS  
A punctal plug and method of treating dry eyes are provided. The punctal plug has two or three layer structure and contains at least one drug, for treating conditions such as dry eyes contained in...
US20150174062 BIODEGRADABLE DRUG DELIVERY SYSTEM  
A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented...
US20120263779 BIODEGRADABLE DRUG DELIVERY SYSTEM  
A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented...
US20120177717 SUSTAINED DRUG DELIVERY SYSTEM  
Disclosed is a drug delivery system for delivering a drug at a sustained constant rate for a long period, which can be transplanted into an affected part safely and in a simple manner and can...
US20100316678 COMBINATION METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROPATHIC PAIN  
The present invention relates generally to the field of pain management, and in particular, the management of neuropathic pain. The present invention further provides methods and compositions that...
US20120264703 Methods And Compositions For The Treatment Of Anxiety Disorders, Including Post Traumatic Stress Disorder (PTSD) And Related Central Nervous System (CNS) Disorders.  
The present invention provides novel methods and formulations for treating anxiety disorders, including Post Traumatic Stress Disorder, in human subjects employing coordinate treatment using α and...
US20110263601 METHODS OF TREATING ULCERATIVE COLITIS  
Methods are disclosed for treating ulcerative colitis and related diseases and disorders, which comprise inhibiting tryptophan hydroxylase (TPH) in patients in need thereof.
US20110046136 METHODS FOR THE PRODUCTION OF FUNCTIONAL PROTEIN FROM DNA HAVING A NONSENSE MUTATION AND THE TREATMENT OF DISORDERS ASSOCICATED THEREWITH  
The present invention relates to functional proteins encoded by nucleic acid sequences comprising a nonsense mutation. The present invention also relates to methods for the production of...
US20120178757 Method For The Prevention Of Cancer Metastasis  
A method is provided for the prevention of cancer metastasis in a patient comprising administering an adrenergic receptor antagonist to a patient in need thereof. The invention also includes an...
US20140303166 COSMETIC METHOD FOR CHANGING THE APPEARANCE OF EYES  
The current application is directed to cosmetic methods for changing the appearance of eyes by causing a retraction of the eyelids so that the eyes appear to be more open and have a wider...
US20110206783 P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN  
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or...
US20120270876 Treatment of Conditions Through Pharmacological Modulation of the Autonomic Nervous System  
Methods are provided for treating a subject for a condition caused by an abnormality in the subject's autonomic nervous system. In accordance with the subject methods, at least a portion of a...
US20150099004 APREPITANT ORAL LIQUID FORMULATIONS  
A liquid pharmaceutical compositions comprising Aprepitant is preferably prepared as an oral suspension dosage form for the prevention and control of acute and delayed chemotherapy induced nausea...
US20110177167 Hydrophilic/Lipophilic Polymeric Matrix Dosage Formulation  
An oral dosage form comprising a pharmaceutical tablet of one or more layers, one of which carries a biologically active substance; the formulation of said tablet includes different percentages of...
US20110098267 TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS  
The invention relates to a topical composition and a method for treating psoriasis. The topical composition comprises one or more compound that inhibits the production of IL-12 and IL-23.
US20140234443 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF  
Novel 5-HT3 receptor modulators are disclosed. These compounds are used in the treatment of various disorders, including chemotherapy-induced nausea and vomiting, post-operative nausea and...
US20100317664 METHODS OF AFFECTING GASTROINTESTINAL TRANSIT AND GASTRIC EMPTYING, AND COMPOUNDS USEFUL THEREIN  
Methods and compounds are disclosed for affecting gastrointestinal motility and gastric emptying, which comprise inhibiting tryptophan hydroxylase (TPH) in patients in need thereof
US20140193523 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF TRAUMA-INDUCED NEUROPATHOLOGY AND NEURODEGENERATION  
Novel multi-component formulations, procedures and methods for use in treating neuropathology and neurodegeneration incident to trauma are provided. Multi-component formulations of the invention...
US20140221375 METHOD FOR TREATING PROLIFERATIVE DISORDERS ASSOCIATED WITH MUTATIONS IN C-MET  
The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating c-Met associated cancers, in a subject in need thereof.
US20130317030 Methods for Diagnosis of Cardiovascular Disease  
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to...
US20150210652 Substituted Triazines for Malaria Treatment and Chemoprophylaxis  
Disclosed herein are triazine compounds and methods of making and using thereof to treat malaria, provide chemoprophylaxis, and/or treat or inhibit infection by one or more Plasmodium spp.
US20120027723 TAURINE OR TAURINE-LIKE SUBSTANCES FOR THE PREVENTION AND TREATMENT OF A DISEASE ASSOCIATED WITH RETINAL GANGLION CELL DEGENERATION  
The present invention relates to taurine or taurine-like substances for the prevention and treatment of a disease associated with retinal ganglion cell degeneration. More particularly the...
US20150104491 SUSTAINED-RELEASE RESERVOIR IMPLANTS FOR INTRACAMERAL DRUG DELIVERY  
The present invention provides a sustained release implant for intraocular use to treat elevated intraocular pressure, which implant is configured for intracameral or anterior vitreal...
US20110319400 PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN  
Disclosed are compounds, compositions and methods for treating pain, including inflammatory, visceral, and acute pain. Such compounds are represented by Formula (I) as follows: wherein A1, L1, D,...
US20120301402 RAP1A AS A MARKER FOR CARDIAC ARRHYTHMIA  
A method for assessing if a subject has or is at risk of developing cardiac arrhythmia is described. The method includes determining the activity of Rap1A protein in a bodily sample of the subject...
US20130035338 EYELID TREATMENT  
The current application is directed topical treatments that improve facial appearance by causing eyelids to naturally open more widely, or be more fully raised, as well as to treatment of ptosis...
US20110158983 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES  
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any...
US20130109674 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING TRIGEMINAL AUTONOMIC CEPHALGIAS, MIGRAINE, AND VASCULAR CONDITIONS  
The present invention relates to, among other things, methods for treating trigeminal cephalgias such as migraine and migraine like headaches and other cerebrovascular conditions associated with...
US20110319404 METHOD FOR TREATING NON-HODKIN'S LYMPHOMA  
The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating non-Hodgkin's lymphoma, in a subject in need thereof.
US20140255386 MICRORNA MODULATORS AND METHOD FOR IDENTIFYING AND USING THE SAME  
The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is...
US20110021526 Pharmaceutical Composition for Treatment of Diabetic Complications  
A method for treating diabetic complications by administration of a beta-blocker is disclosed. Diabetic complications arise from diabetes and have few or no existing treatment options. The present...
US20110237511 EP4 Receptor Agonist, Compositions and Methods Thereof  
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions, which...
US20120028980 USE OF NK-1 RECEPTOR ANTAGONISTS IN MANAGEMENT OF VISCERAL PAIN  
Methods for managing visceral pain in mammalian subjects are described, in which a NK-1 receptor antagonist is administered to the subject before, during or after administration of general...
US20110160186 Methods of Treating CYP2D6 Alternative Metabolizers  
The invention provides various methods comprising the administration of a CYP2D6 bioactive drug covalently bound to a water-soluble oligomer. Metabolism of CYP2D6 bioactive drug conjugates is...
US20140163030 STABLE OPHTHALMIC FORMULATIONS  
Disclosed herein are stable formulations suitable for the treatment of glaucoma and ocular hypertension.
US20110028477 STABLE OPHTHALMIC FORMULATIONS  
Disclosed herein are stable formulations suitable for the treatment of glaucoma and ocular hypertension.
US20110281853 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ATRIAL FIBRILLATION  
The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides administration of muscarinic receptor...
US20130029989 TOPICAL TREATMENTS FOR PAIN  
The present invention relates to novel compositions and therapeutic methods for the treatment of pain, in particular neuropathic, ischemic, muscle, arthritic or multiple sclerosis pain. The...
US20120322804 N-LINKED HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS  
Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.
US20120058056 TREATMENT OF CUTANEOUS HEMANGIOMA  
This invention concerns a method of treating hemangiomas with a beta blocker by applying the beta blocker onto the hemangiomas directly. The invention also concerns a combination therapy by using...
US20150126510 Triazines With Suitable Spacers for Treatment And/Or Prevention of HIV Infections  
The present invention relates to the field of HIV-1 infections, and in particular provides novel compounds containing triazine rings and suitable spacers. The compounds according to this invention...
US20130317013 EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF  
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are...
US20140309185 Inhibiting G Protein Coupled Receptor 6 Kinase Polypeptides  
This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies,...
US20150224115 PRESERVATIVE FREE BIMATOPROST AND TIMOLOL SOLUTIONS  
The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intra-ocular pressure and treatment of glaucoma.
US20140256726 PRESERVATIVE FREE BIMATOPROST AND TIMOLOL SOLUTIONS  
The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intra-ocular pressure and treatment of glaucoma.
US20140148456 PRESERVATIVE FREE BRIMONIDINE AND TIMOLOL SOLUTIONS  
The present invention is directed to preservative-free solutions of brimonidine and timolol for lowering intra-ocular pressure and treatment of glaucoma.
US20140148455 PRESERVATIVE FREE BIMATOPROST AND TIMOLOL SOLUTIONS  
The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intra-ocular pressure and treatment of glaucoma.
US20120225879 SUBSTITUTED 5-IMINO-1,2,4-THIADIAZOLES THAT CAN BE USED TO TREAT NEURODEGENERATIVE DISEASES  
The present invention is based on the use of a broad family of 5-imino-1,2,4-thiadiazoles as potential new drugs for the treatment of diseases in which PDE7 inhibition is important, specially...
US20150133414 COMPOSITIONS AND METHODS FOR IDENTIFYING AND DIAGNOSING SALT SENSITIVITY OF BLOOD PRESSURE  
It was determined whether SNPs in SLC4A5 are associated with salt sensitivity of blood pressure (BP). Subjects consumed an isocaloric constant diet with a randomized order of 7 days low Na+ (10...