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US20080113967 |
ENZYME MODULATORS AND TREATMENTS
Novel compounds and methods of using those compounds for the treatment of inflammatory conditions, hyperproliferative diseases, cancer, and diseases characterized by hyper-vascularization are...
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US20080103128 |
LACTAMS SUBSTITUTED BY CYCLIC SUCCINATES AS INHIBITORS OF ABETTA PROTEIN PRODUCTION
This invention relates to novel lactams having the Formula (I):
to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid...
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US20080085889 |
Amidomethyl-Substituted 1-(Carboxyalkyl) Cyclopentyl-Carbonylamino-Benzazepine-N-Acetic Acid Compounds, Process and Intermediate Products for Their Preparation and Pharmaceutical Compositions Containing Them
Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I,
wherein the substituents R 1 , R 2 , R 3 and R 4 ...
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US20080076755 |
Anti-Inflammatory Agents
The invention provides compounds, compositions, and uses of compounds of general formula (I) or pharmaceutically acceptable salts thereof, for the preparation of a medicament intended to treat an...
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US20080045500 |
Nerve Regeneration Stimulator
A nerve regeneration stimulator comprising a compound having a cholinesterase inhibitory activity, a pharmacologically acceptable salt thereof or a solvate thereof.
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US20080027038 |
N-Acylated lipophilic amino acid derivatives
Compounds of structural formula (I) where A is a lipophilic group including an aliphatic bridging group, B is a lipophilic group, D is a group having at least one amino or substituted amino group...
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US20080026077 |
METHODS AND COMPOSITIONS OF GENE DELIVERY AGENTS FOR SYSTEMIC AND LOCAL THERAPY
A method is provided for the delivery of a therapeutic to epithelial cells through the use of a bile acid conjugated to a peptide, the peptide being ionically charged at physiological pH. The...
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US20080021015 |
Use as medicine of a compound restoring active principles in vivo
A method for delivering at least an active principal A to a human or animal, by administering, in vivo, an active compound of general formula A′ V′ C′, that is capable of restoring at least...
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