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US20140287042 Oral Tablet Formulation Consisting Of Fixed Combination Of Rosuvastatin And Ezetimibe For Treatment Of Hyperlipidemia And Cardiovascular Diseases  
The present invention is an orally consumed fixed combination formulation of both rosuvastatin and ezetimibe in one tablet that is expected to have the same Area Under Curve as two active...
US20130109666 METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER  
Compounds and compositions are described herein for treating post traumatic stress disorder.
US20120071458 METHODS FOR TREATING OBESITY  
The invention is directed to methods for treating and/or controlling obesity in a patient. The methods involve combination therapies using a microsomal triglyceride transfer protein (MTP)...
US20130209401 COMPOSITIONS AND METHODS FOR INHIBITING ENTRY OF A HEPATIC VIRUS  
The present invention embraces Niemann-Pick C1-like 1 protein antagonists and agents that inhibit hepatic virus infection for use in the prevention and treatment of a hepatic virus infection.
US20110171177 Compositions and Methods for Inhibiting Entry of a Hepatic Virus  
The present invention embraces Niemann-Pick C1-like 1 protein antagonists and agents that inhibit hepatic virus infection for use in the prevention and treatment of a hepatic virus infection.
US20140128362 GENETIC POLYMORPHISMS ASSOCIATED WITH VENOUS THROMBOSIS AND STATIN RESPONSE, METHODS OF DETECTION AND USES THEREOF  
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment (particularly for reducing the risk of venous...
US20120108651 GENETIC POLYMORPHISMS ASSOCIATED WITH VENOUS THROMBOSIS AND STATIN RESPONSE, METHODS OF DETECTION AND USES THEREOF  
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment (particularly for reducing the risk of venous...
US20120225113 METHOD FOR TREATING TUBERCULOSIS  
Disclosed is a method for treating a symptom of M. tuberculosis infection in a subject, comprising administering the patient with an effective amount of...
US20140235605 GENETIC POLYMORPHISMS ASSOCIATED WITH STATIN RESPONSE AND CARDIOVASCULAR DISEASES, METHODS OF DETECTION AND USES THEREOF  
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment, particularly for reducing the risk of cardiovascular...
US20110269735 GENETIC POLYMORPHISMS ASSOCIATED WITH STATIN RESPONSE AND CARDIOVASCULAR DISEASES, METHODS OF DETECTION AND USES THEREOF  
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment, particularly for reducing the risk of cardiovascular...
US20120053155 SYSTEM AND METHOD FOR REVERTING ANTIBIOTIC TOLERANCE OF BACTERIAL PERSISTER CELLS  
A system and method for reverting the antibiotic tolerance of persister cells. Brominated furanones, which are quorum sensing inhibitors, are used to revert the antibiotic tolerance of persister...
US20150056274 COMPOSITIONS, METHODS AND KITS FOR REDUCING LIPID LEVELS  
Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of nicotinic acid, nicotinamide riboside and/or...
US20140135305 METHODS FOR TREATING SPINAL MUSCULAR ATROPHY  
The present invention provides nucleic acid constructs, methods for identifying and validating compounds that increase the inclusion of exon 7 of SMN2 into mRNA transcribed from the SMN2 gene,...
US20110086833 METHODS FOR TREATING SPINAL MUSCULAR ATROPHY  
The present invention provides nucleic acid constructs, methods for identifying and validating compounds that increase the inclusion of exon 7 of SMN2 into mRNA transcribed from the SMN2 gene,...
US20100311649 SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS  
Certain novel substituted imidazole 4-carboxamides are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R)....
US20090275551 Fluvastatin for the treatment of patients with a history of muscle related side effects with other statins  
The present disclosure relates to method of using fluvastatin, alone or in combination with ezetimibe, be used to (1) lower cholesterol level, (2) treat hypercholesterolemia, (3) treat mixed...
US20140235607 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CORONARY HEART DISEASE  
The invention pertains to a method of determining a statin dosage for an individual in need of treatment with a statin, comprising determining a SLCO1B1 genotype from a nucleic acid sample of the...
US20130102582 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CORONARY HEART DISEASE  
The invention pertains to a method of determining a statin dosage for an individual in need of treatment with a statin, comprising determining a SLCO1B1 genotype from a nucleic acid sample of the...
US20120084871 NPC1L1 ORTHOLOGUES  
The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
US20130196900 ENHANCEMENT OF INNATE RESISTANCE TO INFECTION  
The present invention provides compounds and compositions that enhance the innate immune system. The present invention comprises methods of preventing, treating or ameliorating an infectious...
US20150157592 METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON STATIN THERAPY  
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a...
US20140155371 MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE  
Provided is a crystalline composition comprising a mixture of a compound of formula 1 (Ezetimibe) and proline or proline derivatives, or a hydrate/solvate thereof, as well as a process for...
US20110027371 Nanoparticulate statin formulations and novel statin combinations  
The present invention is directed to nanoparticulate compositions comprising statin such as lovastatin or simvastatin. The statin particles of the composition have an effective average particle...
US20110262497 NOVEL EZETIMIBE FORMULATIONS  
Formulations of ezetimibe are described, wherein attention is paid, alternatively or optionally in combination, to (i) the existence of ezetimibe in the form of primary particles, which when...
US20110257149 FORMULATION FOR ORAL TRANSMUCOSAL ADMINISTRATION OF LIPID-LOWERING DRUGS  
The invention relates to a formulation for delivering by oral transmucosal administration at least one lipid-lowering active principle, preferably from the statin family, said formulation...
US20140045746 ANTIDIABETIC TRICYCLIC COMPOUNDS  
Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment,...
US20130090323 HETEROCYCLIC COMPOUNDS AND THEIR USES  
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders,...
US20120094972 HETEROCYCLIC COMPOUNDS AND THEIR USES  
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders,...
US20100331293 HETEROCYCLIC COMPOUNDS AND THEIR USES  
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders,...
US20140044668 Methods for Predicting Cardiovascular Risks and Responsiveness to Statin Therapy Using SNPs  
Methods and compositions for the effect of Cholesteryl ester transfer protein (CETP) polymorphisms on mRNA splicing, statin treatment outcome, response to CETP inhibitor drugs, and myocardial...
US20110144052 NIACIN PRODRUGS AND DEUTERATED VERSIONS THEREOF  
The invention relates to prodrugs of niacin and their use in pharmaceutical composition and therapeutic treatment of disease.
US20120009639 CONTROLLING MICROBIAL CONTAMINATION IN ALCOHOLIC FERMENTATION PROCESS  
The control of the microbial contamination during the sugar fermentation in the processes for obtaining alcohol is a very important action to increase the productivity of the alcoholic...
US20140088072 EXTENDED RISK ASSESSMENT PANEL FOR INDIVIDUALIZED TREATMENT OF CARDIOVASCULAR DISEASE, AND METHODS RELATED THERETO  
Disclosed is a personalized diagnostic and treatment solution for cardiovascular disease. The invention comprises an extended CVD risk assessment panel, combining tests for traditional and new...
US20150105365 HETEROARYL LINKED QUINOLINYL MODULATORS OF RORgammat  
The present invention comprises compounds of Formula I. wherein:R1, R2, R3, R4, R5, R6, R7 R8, and R9 are defined in the specification. The invention also comprises a method of treating or...
US20140031332 Biomarkers for Sensitive Detection of Statin-Induced Muscle Toxicity  
The present invention inter alia provides a method, and uses thereof, of predicting statin-induced muscle toxicity or its complications, such as myalgia, myopathy and rhabdomyolysis, by detecting...
US20140066423 POLYCYCLIC BETA LACTAM DERIVATIVES FOR THE TREATMENT OF CANCER  
Provided herein are polycyclic β-lactam compounds, compositions thereof and methods for the treatment and prevention of diseases such as cancer, including pancreatic cancer and pancreatic cancers...
US20150216989 MULTI-DAY DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES  
Compositions and methods for modifying biologically active substances to achieve multi-day delivery of such substances, particularly through oral or parenteral administration, are disclosed. The...
US20110046599 Multi-Day Delivery Of Biologically Active Substances  
Compositions and methods for modifying biologically active substances to achieve multi-day delivery of such substances, particularly through oral or parenteral administration, are disclosed. The...
US20130216625 TREATMENT OF INSULIN RESISTANCE OR DISEASES ASSOCIATED WITH INSULIN RESISTANCE  
The present invention relates to the use of a substance with the core structure of formula (I), or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the manufacture of a...
US20110059936 C-MET PROTEIN KINASE INHIBITORS  
The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides processes for preparing the compounds of this invention, pharmaceutically acceptable...
US20120079616 NPC1L1 (NPC3) AND METHODS OF USE THEREOF  
The present invention provides human, rat and mouse NPC1L1 polypeptides and polynucleotides encoding the polypeptides. Also provided are methods for detecting agonists and antagonists of NPC1L1....
US20120027854 PHARMACEUTICAL COMPOSITION COMPRISING EZETIMIBE AND SIMVASTATIN  
The present invention belongs to the field of pharmaceutical industry and relates to a process for preparing dosage forms containing simvastatin and ezetimibe, comprising the steps of providing a...
US20110177999 Therapeutic Combinations Useful in Treating CFTR Related Diseases  
The present invention relates to therapeutic combinations and kits useful in treating CFTR-related diseases, such as cystic fibrosis.
US20110196383 Atherosclerotic Plaque Dissolution Composition  
A method and chemical composition for modifying and dissolving atherosclerotic plaques formed in a patient's blood vessels is provided. A chemical composition comprising one or more of an organic...
US20110158932 Methods And Compositions For The Treatment of Hyperlipidemia  
Methods and compositions containing a berberine compound or berberine related or derivative compound are provided for the prevention and treatment of hyperlipidemia, elevated cholesterol, and/or...
US20140093518 Chemically Programmed Vaccination  
Provided herein is a method for chemically programmed vaccination. Methods include inducing a covalent-binding polyclonal antibody response in a subject and programming the polyclonal response...
US20110311516 Chemically Programmed Vaccination  
Provided herein is a method for chemically programmed vaccination. Methods include inducing a covalent-binding polyclonal antibody response in a subject and programming the polyclonal response...
US20150168429 Lp(a) SUBFORM SIZE IDENTIFICATION USING ZONAL GEL IMMUNO-FIXATION ELECTROPHORESIS  
In one aspect, a method for determining the composition of individual Lp(a) subforms in a test sample is provided. The method involves providing a test sample comprising Lp(a) subforms obtained...
US20100061968 Reducing Cholesterol Levels with Combined Use of Quercetin and Statin  
A method of reducing the cholesterol level of a subject by administering to that subject quercetin, vitamin C, vitamin B3, and statin.
US20060069080 Combinations of substituted azetidinones and CB1 antagonists  
The present invention provides compositions, therapeutic combinations and methods including: (a) at least one selective CB1 antagonist; and (b) at least one substituted azetidinone or substituted...

Matches 1 - 50 out of 362 1 2 3 4 5 6 7 8 >