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US20100112091 USE OF RAMOPLANIN TO TREAT DISEASES ASSOCIATED WITH THE USE OF ANTIBIOTICS  
The invention features a method of treating or preventing a disease associated with the use of antibiotics in a patient in need thereof by administering to the patient ramoplanin in an amount and...
US20150071992 CONCENTRATED, INHALABLE ANTIBIOTIC FORMULATION  
A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The...
US20100331240 METHODS FOR PREVENTION AND TREATMENT OF INFECTIONS WITH SUPRAPHYSIOLOGICAL DOSES OF MANNAN-BINDING LECTIN (MBL) AND FICOLIN-MBL FUSION PROTEINS  
The present invention provides methods of treatment and/or prevention of infections, for example, viral and bacterial infections, in individuals, wherein the method comprises administering a...
US20110293652 CHIMERIC OSPA GENES, PROTEINS, AND METHODS OF USE THEREOF  
The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA...
US20120244222 OSMOTIC MEDIATED RELEASE SYNTHETIC NANOCARRIERS  
This invention relates, at least in part, to osmotic mediated release barrier-free synthetic nanocarriers and methods of production and use.
US20150132343 SYSTEM AND METHOD FOR THE DETECTION AND TREATMENT OF INFECTION BY A MICROBIAL AGENT ASSOCIATED WITH HIV INFECTION  
A method of treating a patient, comprising administering at least one antibiotic, e.g., doxycycline and ciprofloxacin, sufficient to substantially treat an intracellular bacterial organism present...
US20150164984 Colicins for Treating Bacterial Infections  
The Invention relates to materials and methods for the treatment of conditions associated with bacterial biofilms, intracellular bacterial infections and/or adherent-invasive Escherichia coli...
US20110245150 TARGETS FOR TREATMENT OF CHLAMYDIAL INFECTIONS  
The present invention relates to a screening method for identification of a compound suitable for the prevention, treatment or/and diagnosis of an infection with Chlamydiaceae.
US20130203653 BACTERIAL-DERIVED BLIS FOR TREATMENT OF ACNE  
This invention relates to a treatment of acne. Specifically, the invention is directed to the use of bacteriocin-like inhibitory substances (BLIS), isolated from S. salivarius as bacteriocide or...
US20110262400 PROBIOTIC BACTERIAL MOLECULES AND THEIR USE IN METHODS TO TREAT/PREVENT INFECTION BY HARMFUL BACTERIA AND TO PROVIDE NUTRITIONAL HEALTH  
This invention provides isolated and characterized secreted molecules from probiotic bacteria for use in compositions and methods for the treatment and/or prevention of infection by harmful...
US20120122768 ALGINATE OLIGOMERS FOR USE IN OVERCOMING MULTIDRUG RESISTANCE IN BACTERIA  
The invention provides a method of overcoming resistance to at least one antibiotic in a multidrug resistant bacterium, said method comprising contacting said bacterium with an alginate oligomer...
US20140147414 COMPOSITIONS AND METHODS FOR TREATMENT OF INTRACELLULAR DAMAGE  
Pre-implantation factor (PIF) may be used to treat intracellular damage. Aspects of the invention are directed to a method of treating intracellular damage comprising administering PIF to a...
US20110002994 METHOD OF REGULATING THE TH17 PATHWAY AND ITS ASSOCIATED METABOLIC IMPACT  
It is disclosed a method of immunomodulating an immune response in a subject comprising administering to a subject a malleable protein matrix (MPM), from fermented whey, in an amount effective to...
US20130280297 USE OF TOXOPLASMA GENE PRODUCTS TO PREVENT OR TREAT MICROBIAL INFECTIONS  
The invention provides immunomodulatory proteins, e.g., useful to prevent, inhibit or treat microbial infection.
US20120295839 METHOD OF TREATMENT AND PROPHYLAXIS OF BACTERIAL VAGINOSIS  
Methods of treatment or prophylaxis of bacterial vaginosis, prevention of recurrence of bacterial vaginosis and alleviation or prevention of symptoms or diagnostic criteria of bacterial vaginosis...
US20140010824 Methods, compositions and kits for treating or preventing a disease associated with Gram-negative bacteria  
Compositions, methods and kits are provided for identifying at least one virulence factor of a Gram-negative bacterial strain, and for preparing attenuated bacterial strain vaccines or a modulator...
US20120156237 Novel Antitoxin and Vaccine Platform Based on Nodavirus VLPS  
Antitoxin and vaccine compositions based on nodavirus VLPs are provided. Anthrax antitoxin and vaccine compositions are provided. Methods of treating toxins with VLP-based antitoxins are provided....
US20110033402 Solubilized benzoyl small molecule  
The invention relates to a novel solubilized small molecule topical formulation for the transdermal delivery of small molecule agents comprising: a small molecule agent, one or more micelle...
US20140148379 Control of Unwanted Bacteria in Fermentation Systems with Bacteriocin  
A method of controlling unwanted bacteria in fermentation processes comprising contacting reactants of the process with an effective amount of bacteriocin. Bacteriocin, both indigenous and...
US20110262411 BACTERIOPHAGE DERIVED METHODS TO CONTROL LACTIC ACID BACTERIAL GROWTH  
Compositions and methods for protection against bacterial contamination are disclosed Antibacterial proteins and methods of use thereof are also disclosed
US20140179594 STREPTOCOCCUS BACTERIOPHAGE LYSINS FOR TREATMENT OF GRAM POSITIVE BACTERIA IN COMPANION ANIMALS AND LIVESTOCK  
The present invention provides methods for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria in companion animals and livestock, including Streptococcus and...
US20120219589 FORMULATION OF DRUGS AND VACCINES IN THE FORM OF PERCUTANEOUS INJECTABLE NEEDLES  
The invention relates to percutaneous administration of drugs and vaccines in form of solid penetrating needles, “injectable needles”, comprising a polymeric matrix resulting from the...
US20110274708 SHORT-FORM HUMAN MD-2 AS A NEGATIVE REGULATOR OF TOLL-LIKE RECEPTOR 4 SIGNALING  
The present invention is based on a novel, alternatively spliced human isoform of MD-2 (MD-2s). In addition, the present invention relates to modified MD-2 proteins, wherein one or more tyrosine...
US20150126433 GROWTH FACTORS FOR THE TREATMENT OF MYCOBACTERIAL INFECTION  
Described herein are novel methods and kits for treating mycobacterium infections with KGF. The methods include administering an amount of KGF effective to treat the mycobacterium infection. The...
US20150238557 METHOD OF TREATMENT OR PROPHYLAXIS OF INFECTIONS OF THE EYE  
A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that...
US20120252720 COMPOSITIONS FOR TREATMENT OF EAR DISORDERS AND METHODS OF USE THEREOF  
The present invention relates to compositions and methods useful for the treatment of ear disorders, administered to a treated ear in the form of a foam or a mousse. Administering a medicament in...
US20110311462 COMPOSITIONS FOR TREATMENT OF EAR DISORDERS AND METHODS OF USE THEREOF  
The present invention relates to compositions and methods useful for the treatment of ear disorders, administered to a treated ear in the form of a foam or a mousse. Administering a medicament in...
US20120071397 Methods for Hematopoietic Stem Cell Transplantation  
The present invention provides methods for treating a subject undergoing hematopoietic stem cell transplantation, methods for increasing a subject's resistance to bacterial or viral infection...
US20130202646 COMPOSITIONS AND METHODS FOR MODULATING AUTOPHAGY  
In alternative embodiments, the invention provides cell-permeable recombinant or synthetic proteins to modulate autophagy, including a Tat-Atg5K130R (inhibitor of autophagy) and a Tat-Beclin 1...
US20060120993 Treatment of lesions of the soft tissues  
The invented remedy allows cleaning up the area from necrotic tissues and facilitating reduced perifocal oedema and infiltration as well as lessening pain syndrome during suppurative inflammation...
US20140256614 COMPOSITIONS AND METHODS FOR AUGMENTING PERMEABILITY BARRIERS  
Compositions and methods for activating MK2, augmenting permeability barriers, such as epithelial and/or endothelial barriers, and treating diseases, conditions, disorders, and/or injuries...
US20140038882 Stable Pexiganan Formulation  
The invention provides chemically and physically stable topical formulations of pexiganan, and methods of preparing the same.
US20140037634 REGULATORY T CELL MEDIATOR PROTEINS AND USES THEREOF  
The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates αCD3 proliferation of T cells in vitro. A...
US20130203652 DIFFOCINS AND METHODS OF USE THEREOF  
This disclosure relates to the discovery and isolation of the entire cluster of genes encoding R-type high molecular weight bacteriocins that specifically kill Clostridium difficile bacteria,...
US20110046039 POST-EXPOSURE PROPHYLAXIS AND TREATMENT OF INFECTIONS  
The invention provides methods and materials for identifying agents for preventing and/or treating anthrax and similar diseases. Embodiments provide strains and model systems for studying...
US20110104180 NEW VACCINE FOR THE TREATMENT OF MYCOBACTERIUM RELATED DISORDERS  
The invention relates to genes and proteins involved in the sporulation of Mycobacteria and the use thereof in the technical fields of immunology and medicine. A vaccine comprising spore forming...
US20140274876 CARIES RISK TEST FOR PREDICTING AND ASSESSING THE RISK OF DISEASE  
Provided are methods, test devices, and diagnostic kits for predicting, assessing, and diagnosing the risk of a disease using salivary analysis. The methods comprise providing a whole...
US20110293566 DIFFOCIN AND METHODS OF USE THEREOF  
This disclosure relates to the discovery and isolation of the entire cluster of genes encoding R-type high molecular weight bacteriocins that specifically kill Clostridium difficile bacteria,...
US20150140186 CLOSTRIDIUM BOTULINUM CONTROL IN MIDLY PROCESSED REFRIGERATED FOOD PRODUCTS  
The protection of low-acid, high moisture and/or high water activity processed food products against outgrowth of Clostridium botulinum. It was surprisingly found that combinations of propionic...
US20120289452 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NECROSIS  
A method for treating and/or preventing cell necrosis and diseases associated therewith, comprising the inhibition of one or more elastase enzymes within said cells.
US20150018268 MULTIVALENT SYNTHETIC COMPOUNDS AS ANTIBIOTIC TREATMENT  
The present invention relates to the use of a multivalent synthetic compound, which is significantly more resistant to at least one protease than a standard peptide bond, for preparing a...
US20120238998 Octanoate-reduced Human Albumin  
A method is described that improves the transport properties of albumin produced on an industrial scale, wherein the albumin is mixed, during the production process, with substances that saturate...
US20110034371 L. CASEI RHAMNOSUS SECRETED FACTORS AND USE THEREOF  
The present invention relates to a composition for inhibiting gastrointestinal inflammation comprising an effective amount of Lactoacillus casei rhamnosus secreted factors 5 to 30K fraction.
US20120263667 COMPOSITION AND METHOD FOR MODULATING AND MAINTAINING VAGINAL BACTERIAL FLORA AND VAGINAL ACIDITY  
The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating...
US20140274880 MOSQUITOCIDAL XENORHABDUS, LIPOPEPTIDE AND METHODS  
Provided is a bacterial strain which produces a family of mosquitocidal toxins, Xenorhabdus MT, on deposit with the American Type Culture Collection, PTA-6826, insecticidal compositions comprising...
US20100061994 MEDICAL USES OF 39-DESMETHOXYRAPAMYCIN AND ANALOGUES THEREOF  
The present invention relates to medical uses of 39-desmethoxyrapamycin analogues.
US20110110939 METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF SYSTEMIC ANTHRAX INFECTION  
The present invention features methods and kits that utilize Ang-2 antagonists for the treatment, inhibition, and prevention of a systemic anthrax infection. The invention described herein also...
US20120331576 Pathogen Restriction Factors  
The use of interferon induced transmembrane protein 1, 2, or 3 (IFITM1, 2, or 3) as a viral restriction factor, and methods of using the same to produce virus, transgenic animals expressing...
US20120184482 Novel Ubiquitin-Isopeptide Probes  
The invention relates to a ubiquitin-isopeptide probe (hereinafter also referred to as UIPP), a method for its preparation, and its use. The invention also provides a method for isolating a...
US20120128701 COMPOSITIONS AND METHODS FOR THE REMOVAL OF BIOFILMS  
Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or...