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US20110250153 OLIGOMERIC BIOSURFACTANTS IN DERMATOCOSMETIC COMPOSITIONS  
Oligomeric acylated biosurfactants (“OABs”) having low critical micelle concentrations of from about 1.0 ppm to about 200 ppm, preferably less than about 50 ppm, in an aqueous solution of Minimal...
US20130035283 ENGINEERED OPSONIN FOR PATHOGEN DETECTION AND TREATMENT  
The present invention provides for engineered molecular opsonins that may be used to bind biological pathogens or identify subclasses or specific pathogen species for use in devices and systems...
US20110123517 DISSOLVABLE PHARMACEUTICAL IMPLANT  
A pharmaceutical implant may include a pharmaceutical and at least one excipient, and may be configured to be implanted in a body of a patient. The at least one excipient may dissolve after...
US20150010509 CALCIUM FOLATE (CAFOLATE) AND THERAPEUTIC METHODS BASED THEREON  
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection, tuberculosis and type 2 diabetes based upon the...
US20100331240 METHODS FOR PREVENTION AND TREATMENT OF INFECTIONS WITH SUPRAPHYSIOLOGICAL DOSES OF MANNAN-BINDING LECTIN (MBL) AND FICOLIN-MBL FUSION PROTEINS  
The present invention provides methods of treatment and/or prevention of infections, for example, viral and bacterial infections, in individuals, wherein the method comprises administering a...
US20150197766 METHODS AND COMPOSITIONS FOR PRODUCTION OF RECOMBINANT PHARMACEUTICAL PROTEINS IN MEDICINAL PLANTS  
Methods of tissue culture and in vitro propagation of medicinal plants, in particular, plants of the genera Hydrastis, Echinacea, Kalanhoe, Thymus and Calendula are described. Methods of...
US20130022661 BIO-REMODABLE BONE AUGMENTATION DEVICE AND METHOD  
A bio-remodable augmentation device including an implantable member configured for maintaining space in a bone defect. The implantable member is formed from a bio-remodable composite having...
US20120201901 Topical Antibiotic Formulations  
A biocompatible putty formulation suitable for insertion within chronic and acute wounds of humans and animals, the formulation containing a topical antibiotic, a biocompatible humectant, a...
US20120244222 OSMOTIC MEDIATED RELEASE SYNTHETIC NANOCARRIERS  
This invention relates, at least in part, to osmotic mediated release barrier-free synthetic nanocarriers and methods of production and use.
US20110076316 SCALABLE MATRIX FOR THE IN VIVO CULTIVATION OF BONE AND CARTILAGE  
The present invention provides implantable receptacle devices (and methods) for use in bone and tissue regeneration which provide immediate structural stability and strength to a zone where tissue...
US20120278954 Pesticidal Nucleic Acids and Proteins and Uses Thereof  
The invention provides compositions comprising polynucleotide molecules encoding certain pesticidal polypeptides which exhibit plant parasitic nematode and/or insect control properties, and are...
US20130172235 ORAL TREATMENT OF INFLAMMATORY BOWEL DISEASE  
The present invention relates to treatment of an inflammatory bowel disease by simultaneous or successive parental and oral administration of a mammalian beta defensin.
US20120028882 METHOD FOR REMOVING ENDOTOXIN FROM PROTEINS  
Disclosed is a method for removing endotoxin from proteins. Also disclosed are products made by using the method. The method may be used, for example, to produce endotoxin-free lactoferrin. Bovine...
US20120219616 LIPOSOMAL REDUCED GLUTATHIONE AND l-ARGININE, INCLUDING WITH OTHER INGREDIENT(S), CAPABLE OF MULTIPATH ADMINISTRATION FOR REVERSAL AND PREVENTION OF OBESITY AND FOR MITOCHONDRIAL BIOGENESIS  
The invention enables management of mammalian disease related to decreased energy production in the mitochondria by a combination of liposomal reduced glutathione and 1-arginine. For individuals...
US20150023912 COMBINATIONS OF ALBUMIN-BASED DRUG DELIVERY SYSTEMS  
The present invention relates to a composition comprising at least two different albumin-based drug delivery systems, as well as to a pharmaceutical composition comprising said composition.
US20110207656 MUC1, CASPASE-8, and DED-CONTAINING PROTEINS  
The disclosure features a variety of compositions and methods for modulating an interaction between MUC1 and caspase-8 and/or an interaction between MUC1 and a DED-containing protein (e.g., an...
US20110091543 ORAL DELIVERY OF MODIFIED TRANSFERRIN FUSION PROTEINS  
Pharmaceutical compositions containing modified fusion proteins of transferrin and therapeutic proteins or peptides with increased serum half-life or increased serum stability are disclosed....
US20110189304 ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS  
The present invention relates to mechanically hemostatic body-absorbable compositions having a putty-like consistency. The compositions preferably comprise a finely powdered, carboxylic acid salt...
US20110002994 METHOD OF REGULATING THE TH17 PATHWAY AND ITS ASSOCIATED METABOLIC IMPACT  
It is disclosed a method of immunomodulating an immune response in a subject comprising administering to a subject a malleable protein matrix (MPM), from fermented whey, in an amount effective to...
US20130280297 USE OF TOXOPLASMA GENE PRODUCTS TO PREVENT OR TREAT MICROBIAL INFECTIONS  
The invention provides immunomodulatory proteins, e.g., useful to prevent, inhibit or treat microbial infection.
US20110245149 METHODS TO PREVENT AND TREAT DISEASES  
This invention discloses methods and compositions that can treat a variety of tissue injuries and infections. Tissue-derived leukocyte chemotactic factors are rapidly released after injury to...
US20130164370 NOVEL FORMULATION OF PEGYLATED-LIPOSOME ENCAPSULATED GLYCOPEPTIDE ANTIBIOTICS  
This invention is directed to a novel method of treating an individual suffering from a bacterial infection, such as bacterial infections of various tissues or organs of an individual. In general,...
US20140113855 Modified Release Formulations for Oprozomib  
This disclosure features modified release pharmaceutical formulations (e.g., extended release pharmaceutical formulations; e.g., solid dosage forms, e.g., tablets) that are useful for the oral...
US20110144002 Use of AMPs for Treatment of UTI/Cystitis  
The present invention relates to methods for treating urinary tract infections, such as cystitis, with antimicrobial polypeptides polypeptides.
US20130209522 Drug Release from a Polymer-Controlled Local Antibiotic Delivery System Using a Degradable Bone Graft  
In some embodiments, the invention provides an implant comprising a uniform mixture of degradable polymer, bone, and a drug. In some embodiments, the drug comprises an antibiotic. In some...
US20130310307 METHODS AND COMPOSITIONS FOR TREATMENT OF MULTIDRUG-RESISTANT BACTERIAL AND FUNGAL INFECTIONS  
The invention provides a method of killing an infectious microbe by administering an effective amount of transferrin to an individual having a microbial infection, wherein the transferrin has...
US20150238557 METHOD OF TREATMENT OR PROPHYLAXIS OF INFECTIONS OF THE EYE  
A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that...
US20110033469 LEUKOTRIENE B4 BINDING SOLUBLE LIPOCALIN RECEPTOR FROM IXODES RICINUS  
Leukotriene B4 binding polypeptide is obtained from Ixodes ricinus, the polynucleotide and related polypeptides may be used as research reagents and materials for the development of treatments and...
US20150174302 Compositions And Methods For Coating Implant Surfaces To Inhibit Surgical Infections  
Infection-inhibiting compositions suitable for coating surfaces of implantable medical implants, including compositions and devices for coating medical devices in the operating room prior to...
US20130288951 COMPOSITIONS AND METHODS FOR COATING IMPLANT SURFACES TO INHIBIT SURGICAL INFECTIONS  
Infection-inhibiting compositions suitable for coating surfaces of implantable medical implants, including compositions and devices for coating medical devices in the operating room prior to...
US20130108670 COMPOSITIONS AND METHODS FOR TREATING FULL THICKNESS BURN INJURIES  
The present invention provides compositions and methods for treating full thickness burn injuries. The present invention provides compositions and methods for promoting healing and regeneration of...
US20100311645 PROTEINS FROM THE WEBS OF NEPHILENGYS CRUENTATA, AVICULARIA JURUENSIS AND PARAWIXIA BISTRIATA SPIDERS ISOLATED FROM BRAZILIAN BIODIVERSITY  
The Present invention relates to molecules isolated from the nucleic acid that encodes spider web proteins or fragments of these or other derivatives of these. The invention also refers to a...
US20110212079 ADAPTIVE BIOCHEMICAL SIGNATURES  
The present invention is related to methods of generating adaptive biochemical signatures in live cells and the use of said signatures to identify diagnostic and therapeutic modalities for human...
US20110189257 NANOPARTICLE BASED THERAPY FOR AGGREGATING MUCIN  
There are provided compositions and methods to aggregate mucus using a plurality of positively charged nanoparticles. There are also provided compositions and methods for inducing contraception in...
US20110158983 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES  
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any...
US20130280223 FUNCTIONALIZED TISSUE MATRICES  
Disclosed herein are tissue treatment products that have been bound to at least one chelating agent. Also disclosed are tissue treatment products that have been functionalized with at least one...
US20110130326 DEFENSINS FOR TREATMENT OF INFECTIVE ENDOCARDITIS  
The present invention relates to methods for treating infective endocarditis, such as bacterial endocarditis, with defensin polypeptides.
US20120213732 TARGETED DELIVERY OF ANTIVIRAL COMPOUNDS THROUGH HEMOGLOBIN BIOCONJUGATES  
This invention relates to targeted delivery of anti-viral compounds through protein bioconjugation. More particularly, it relates to an anti-viral compound conjugated to a protein, such as...
US20110020375 STROMAL CELL-DERIVED FACTOR-1 POLYPEPTIDES, POLYNUCLEOTIDES, MODULATORS THEREOF AND METHODS OF USE  
Disclosed herein is a newly identified SDF-1 splice variant molecule, its polypeptide sequence, and the polynucleotides encoding the polypeptide sequence, and active fragments thereof. Also...
US20110171232 METHODS OF TREATING AUTOIMMUNE DISEASES CAUSED BY SMALL INTESTINAL BACTERIAL OVERGROWTH  
Disclosed is a method of diagnosing autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, which involves detecting the presence of small intestinal bacterial overgrowth...
US20110038809 Growth control of oral and superficial microorganisms using gallium compounds  
The present invention provides methods for treating or preventing diseases and disorders caused by iron-dependent pathogenic microorganisms, such as bacteria, fungi, and parasites, by applying a...
US20130303437 ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS  
The disclosure provides a molecular genetic approach of targeted mutagenesis and heterologous expression, coupled with in vitro and in vivo models of bacterial pathogenesis, to demonstrate that...
US20130108682 WOUND CARE PRODUCT COMPRISING A CATHELICIDIN POLYPEPTIDE  
The present invention provides a wound care product comprising a wound care material and a polypeptide having wound care properties. In one embodiment, the wound care material comprises or...
US20130251689 KERATIN COMPOSITIONS FOR TREATMENT OF BONE DEFICIENCY OR INJURY  
A bone graft composition is described, with one or more of: (a) keratose; (b) kerateine; (c) optionally, particulate filler; (d) optionally, an antibiotic; and (e) water or saline. The composition...
US20110002888 Albumin Fusion Proteins  
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors...
US20120070449 METHODS OF TREATING INFLAMMATION  
A method of treating an inflammation in a subject in need thereof is disclosed. The method comprising administering to the subject an agent capable of down-regulating an activity or expression of...
US20110236367 RAT CATHESPIN DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE AND ITS USES  
The present invention relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, modified dipeptidyl peptidase I (DPPI) proteins and DPPI co-complexes. Included in the present...
US20140051625 Bone Targeted Therapeutics and Methods of Making and Using the Same  
The present invention provides novel bisphosphonate conjugates, pharmaceutical compositions comprising bisphosphonate conjugates and methods of using such analogs in the treatment of bone cancer,...
US20110002877 PTEN Inhibitors Treat Neutropenia-Associated Pneumonia  
Neutropenia-associated pneumonia is treated with a therapeutically effective amount of a small-molecule PTEN inhibitor. The method may further include detecting a resultant alleviation of the...
US20140274880 MOSQUITOCIDAL XENORHABDUS, LIPOPEPTIDE AND METHODS  
Provided is a bacterial strain which produces a family of mosquitocidal toxins, Xenorhabdus MT, on deposit with the American Type Culture Collection, PTA-6826, insecticidal compositions comprising...