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US20120309676 Lantibiotic Salts  
Described are certain salts of certain lantibiotic compounds, pharmaceutical compositions comprising the same and use of the salts and compositions for the treatment of microbial infection,...
US20100204127 USE OF A BOTULINUM NEUROTOXIN TO ALLEVIATE VARIOUS DISORDERS  
Methods for treating obsessions and compulsions by local administration of a Clostridial toxin. The obsessions or compulsions can be eye poking, body rocking, finger biting, counting, checking and...
US20140142025 Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent  
The disclosure describes collagen constructs comprising antimicrobial agents and related methods.
US20100172922 Expression and Purification of HIP/PAP and Uses Therefor  
The present invention relates to methods of compositions comprising RegIII and HIP/PAP proteins, including the use of such proteins as diagnostic and therapeutic targets.
US20060275266 Tripeptide of FcyRIIA  
The present invention relates, in general, to phagocytosis and phagolysosomal fusion and, in particular, to a tripeptide of FcγRIIA that mediates trafficking of targets phagocytosed via FcγRIIA to...
US20110033526 PHARMACEUTICAL COMPOSITION OF ANTIBIOTICS AND PREBIOTICS FOR PREVENTING AND TREATING DYSBIOSIS DURING ANTIBACTERIAL THERAPY  
The invention relates to medicine and pharmacology, in particular to pharmaceutical compositions containing the following antimicrobial preparations: antibiotics and sulphanylamides combined with...
US20110301077 METHOD FOR PRODUCTION OF LACTOFERRIN  
The invention concerns a method for production of lactoferrin comprising at least the steps of: a) disposing of raw material that have not been treated at a temperature greater than 500 C, b)...
US20120003203 Compositions and Methods for Treating S. Pneumoniae Infection  
The present invention relates to novel compounds that are useful for inhibition and prevention of pathogen cell adhesion and cell adhesion-mediated pathologies. This invention also relates to...
US20150080292 Cyclic lipopeptide antibiotic Locillomycin (Locillomycin-A, Locillomycin-B, Locillomycin-C) and methods of making and using the same  
This invention provides new cyclic lipopeptide antibiotic Locillomycin (Locillomycin-A, Locillomycin-B, Locillomycin-C) that display very strong antifungal, antibacterial, antivirus activities in...
US20140206602 BIPARTITE INHIBITORS OF BACTERIAL RNA POLYMERASE  
The invention provides bipartite inhibitors of bacterial RNA polymerase having the general structural formula (I): X-α-Y (I) wherein X is an moiety that binds to the rifamycin binding site of a...
US20090148502 COMPOSITIONS AND METHODS FOR TREATING LACERATIONS, ABRASIONS, AVULSIONS, BURNS, ULCERS, AND CASES OF EXCESSIVE BLEEDING  
Described herein are compositions and methods related to wound treatment. Compositions are multi-components admixed in amounts and ratios to meet specific objectives for optimally treating various...
US20070110741 SINGLE-WALL CARBON NANOTUBE-EGG WHITE PROTEIN COMPOSITE AND PREPARATION THEREOF  
The present invention relates to single-wall carbon nanotube-egg white protein composite, an aqueous dispersion comprising the same and preparation method thereof. The EW-SWNT obtained by reacting...
US20060241048 Modified therapeutic agents  
The invention provides a modified therapeutic agent, said modified agent comprising three or more membrane binding elements with low membrane affinity covalently associated with the agent which...
US20080075742 Compositions Comprising Fetal Hemoglobin and Bacterial Endotoxin and Optionally Additional Fetal Liver Components  
The present invention relates to a pharmaceutical composition representing a novel immunomodulating principle comprising bacterial endotoxin, fetal hemoglobin or more particularly a heme-free...
US20110044969 Antimicrobial Agents for the Treatment of Campylobacter Species in the Crop of a Bird  
The invention provides an antimicrobial agent for use in the treatment of a Campylobacter species which has colonised the crop of a bird, wherein the bird is exposed to said antimicrobial agent...
US20050095245 Pharmaceutical delivery system  
A pharmaceutical formulation to treat vaginal conditions in a human patient comprises: at least one active agent; a modified release dosage form which provides extended release of the...
US20110028385 Combination of Immunomodulator and Anti-Pathogenic Agent  
A compound comprising combination of an immunomodulator and to at least one anti-pathogenic agent for treating of facultative or strict infections caused by intracellular microorganisms, the...
US20100111937 Modulation of Toll-Like Receptor 5 Expression by Antisense Oligonucleotides  
Antisense oligonucleotide compounds, compositions and methods are provided for down regulating the expression of TLR5. The compositions comprise antisense oligonucleotides targeted to nucleic...
US20090081194 COMPOSITIONS AND METHODS FOR REDUCING RISK OF DEVELOPMENT, OR SEVERITY, OF INAPPROPRIATE IMMUNE RESPONSE IN EYES  
A composition for reducing the risk of development, or severity, of an inappropriate immune response in an eye comprises an antagonist to at least a human TLR, an antagonist to at least a...
US20050159360 Compositions for the transport of therapeutic molecules into the lungs and use thereof for the treatment of lung cancers and pulmonary diseases  
A pharmaceutical composition including at least one therapeutic molecule effective for treating lung cancers or pulmonary diseases; and at least one peptide vector that augments bioavailability of...
US20110274651 Noscapine and Noscapine Analogs and Their Use in treating Infectious Diseases by Tubulin Binding Inhibition  
Compositions and methods for treating or preventing infectious diseases, and inhibiting the ability of microbes to travel within mammalian cells, and inhibiting microbial replication, are...
US20090297502 CCR2 ANTAGONISTS FOR CHRONIC ORGAN TRANSPLANTATION REJECTION  
Anti-chemokine monoclonal antibody therapy is provided for the prevention, control or reversal of chronic rejection mediated vascular remodeling, including, e.g., but not limited to MCP-1/CCR2...
US20100029557 ALPHA-LACTALBUMIN COMPOSITION  
The present invention relates to a pharmaceutical composition comprising monomeric alpha-lactalbumin complex, preferably LAC, which is an active complex of alpha-lactalbumin and a fatty acid or...
US20070213258 Endotoxin adsorbent, and method for removing endotoxin using the same  
[OBJECT] The present invention provides a method for selecting and eliminating endotoxin selectively from a solution where a highly acidic substance such as heparin co-exists, and an adsorbent...
US20050084511 Lumen formation-inducible material and instrument to be inserted into the body  
The present invention discloses a fistula formation-inducing material having a property of forming a fistula wherein cells are exposed on at least a portion of the fistula luminal surface. This...
US20120058935 ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREFORE  
The invention features antimicrobial compositions comprising β-amyloid peptides, oligomers, and analogs thereof, and methods of using them for the prevention or treatment of an infection.
US20080124310 Bead based receptor biology  
A method for capturing activated receptor signaling complexes from live cells, utilizing bead based biology wherein live cells are contacted with ligand coated beads to form bead binding sites and...
US20100158921 COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY  
The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of...
US20070135353 Crystalline n-formyl hydroxylamine compounds  
Certain N-formyl hydroxylamine compounds, such as N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylami no-aryl or -heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes or...
US20100196317 CYCLIC UNDECAPEPTIDES AND DERIVATIVES AS MULTIPLE SCLEROSIS THERAPIES  
A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to...
US20070172448 Method for detecting the specificity of activated lymphocyte  
A method for detecting the specificity of activated lymphocytes is provided. The present method can be used to detect the specificity of activated lymphocytes in recipients or patients after organ...
US20110082074 AGENT FOR PREVENTING PERIODONTAL DISEASE  
The present invention provides a pharmaceutical agent that is useful for preventing periodontal disease. The pharmaceutical agent contains a compound in which a mucin-type sugar chain-binding...
US20110117106 USES OF CALPAIN INHIBITORS TO INHIBIT INFLAMMATION  
Calpains target junctional components that normally seal the epithelium, forming tight junctions. This selective targeting by calpains facilitates the transmigration of leukocytes across the...
US20090081164 Use of a cyclosporin for the treatment of hepatitis C infection and pharmaceutical composition comprising said cyclosporin  
This invention relates to the use in the treatment of HCV infection, either as single active agents or in combination with another active agent, of a cyclosporin having increased cyclophilin...
US20100303822 Polypeptides from non-typeable haemophilus influenzae  
Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic...
US20100120667 COMPOSITION FOR PREVENTING AND/OR TREATING PEPTIC ULCERS  
A composition for effectively preventing or treating peptic ulcers not caused by Helicobacter pylori that does not cause any adverse reaction and thus is highly safe is provided. The present...
US20100009912 INSECTICIDAL EXTRACT FROM LEGUME PLANTS AND METHOD OF PREPARING THE SAME  
The invention may be summarized as follows. The present invention provides insecticides comprised of naturally-occurring compounds, such as, for example, PA1b-related peptides and terpenoid...
US20140065094 POLYMER CONJUGATES OF BOX-A OF HMGB1 AND BOX-A VARIANTS OF HMGB1  
The present invention relates to novel polymer conjugates of polypeptide variants of the HMGB1 high affinity binding domain Box-A (HMGB1 Box-A) or of a biologically active fragment of HMGB1 Box-A....
US20100260706 COMPOSITIONS AND METHODS FOR IMPROVING PRODUCTION OF RECOMBINANT POLYPEPTIDES  
The present invention relates to biologically active polypeptides linked to one or more accessory polypeptides. The present invention also provides recombinant polypeptides including vectors...
US20060222696 Novel liposome compositions  
The present disclosure provides lipid-containing compositions, including targeted liposomes encapsulating drug, and pharmaceutical formulations thereof, as well as methods for the making and using...
US20090148460 EXOSOME LIGANDS, THEIR PREPARATION AND USES  
The present invention relates to exosome-specific ligands and compositions comprising the same. The invention also relates to methods of generating said ligands and compositions, to methods of...
US20100135956 STEROID MODULATORS OF PROGESTERONE RECEPTOR AND/OR GLUCOCORTICOID RECEPTOR  
The present invention relates to new steroid modulators of progesterone receptor activity and/or glucocorticoid receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
US20100143379 MIF AGONISTS AND ANTAGONIST AND THERAPEUTIC USES THEREOF  
The present invention relates to methods and compositions for selecting a subject for treatment with an agonist or antagonist of macrophage migration inhibitory factor (MIF), identifying a subject...
US20110245148 ACETIC ACID AND A BUFFER  
The present invention relates to a composition comprising: a) 0.01-20% wt/wt acetic acid and b) a physiologically tolerable buffer capable of maintaining acetic acid at a pH in the range of 2-7;...
US20140017273 Albumin-Fused Anti-Angiogenesis Peptides  
The present disclosure relates to albumin fusion protein including an angiogenesis inhibiting peptide, or a fragment or variant thereof, and albumin, or a fragment or variant thereof. The fusion...
US20110230394 Processes Using Antibiotic Alternatives In Bioethanol Production  
Methods for controlling the growth of bacteria in ethanol fermentation systems with antibiotic alternatives, which can be nonoxidizing biocides, stabilized oxidizers, or any combinations thereof,...
US20050043223 Methods for reducing or preventing transmission of nosocomial pathogens in a health care facility  
The present invention provides methods and compositions useful for reducing or preventing the transmission of nosocomial pathogens or an epidemic of nosocomial pathogens in a health care facility...
US20100215699 LACTOFERRIN AS A RADIOPROTECTIVE AGENT  
This present invention relates to the field of protecting against, or rectifying the effects of damaging ionizing irradiation. The method of treatment involves oral administration of a lactoferrin...
US20130072422 COMPOUNDS FOR IMMUNOPROTEASOME INHIBITION  
One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the...
US20080050434 Novel Composition for Topical Delivery  
Pharmaceutical composition for topical administration comprising of at least one active ingredient, its salts, esters, hydrates or derivatives; a gelator system consisting of a fiend of...