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US20110293557 CONJUGATES FOR THE ADMINISTRATION OF BIOLOGICALLY ACTIVE COMPOUNDS  
The invention relates to a conjugate that comprises an Apo A molecule or a functionally equivalent variant thereof and a compound of therapeutic interest wherein both components are covalently...
US20140271861 MATRIX COMPOSITIONS FOR CONTROLLED RELEASE OF PEPTIDE AND POLYPEPTIDE MOLECULES  
The present invention provides compositions for controlled release of a peptidic molecule comprising a lipid-saturated matrix comprising a biocompatible polymer and a peptidic molecule associated...
US20110245152 ANTIBIOTIC ANTIMICROBIAL AGENTS AND METHODS OF THEIR USE  
The present invention relates to a novel Paenibacillus polymyxa strain, OSY-DF, and its bioactive mutants. Also provided is a method for using a novel antimicrobial peptide, paenibacillin,...
US20050118206 Surfactant-based gel as an injectable, sustained drug delivery vehicle  
The present invention provides methods and compositions for the sustained delivery of beneficial agents. In certain embodiments, the invention provides compositions comprising a surfactant, a...
US20130011398 Serpin Fusion Polypeptides and Methods of Use Thereof  
This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence that is derived from a serpin and...
US20100086594 WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF  
The present invention provides water-soluble reactive esters of carboxy polysaccharides and derivatives thereof. The reactive carboxy polysaccharide derivatives are useful per se in aqueous...
US20060105048 Remedy  
It is intended to provide a remedy for diseases caused by macrophages with dysfunction or mediated by macrophages. Namely, a remedy which activates the phagocytic capacity of macrophages and thus...
US20100240583 SOLUBLE PROTEIN AND UTILIZATION OF THE SAME  
The present invention relates to a method for screening a medicine using a protein, and a compound obtained by the screening method. A compound or a salt thereof inhibiting activity or expression...
US20110091570 Compositions and Devices for Antisepsis and Anticoagulation  
Disclosed herein are compositions, methods, uses, and devices having antiseptic and anticoagulation properties in a mammal. The compositions, methods, uses, and devices are based on a...
US20110088128 POLYPEPTIDE EXTRACTED FROM PLANTS OF THE GENUS LUPINUS OR PRODUCED IN RECOMBINANT FORM, NUCLEOTIDE SEQUENCE ENCODING IT AND ITS USE IN ANIMAL NUTRITION, AS A PLANT GROWTH PROMOTER AND IN THE FIGHT AGAINST PATHOGENIC FUNGI  
This invention is related to a protein from the seeds, cotyledons or plantlets of Lupinus genus, as well as to the way of producing the protein in recombinant form and of expressing the protein in...
US20150182657 ACTIVE POLYMER LAYER MADE OF CHITIN DERIVATIVES, ESPECIALLY FOR A DRESSING, AND ITS USE  
The invention refers to an active polymer layer (1) especially for a dressing of a three-dimensional structure characterized in that it has non-fibrous structure made of chitin derivatives...
US20070104809 Composition comprising a bacteriocin and an extract from a plant of the labiatae family  
The present invention provides a composition comprising (a) an antimicrobial material; and (b) an extract obtained from or obtainable from a plant of the Labiatae family, wherein (a) and (b) are...
US20070238652 Neutralization of bacterial spores  
The present invention relates to the field of bacteriology. In particular, the present invention provides compositions (e.g., a lantibiotic-based spore decontaminant (e.g., comprising nisin)) and...
US20070099823 Inhibitors of sporeforming pathogens and applications of the same  
An inhibitor of sporeforming pathogens or agents. In one embodiment, the inhibitor has at least one glycoconjugate that is bondable to a sporeforming pathogen or agent. The glycoconjugate is a...
US20060153893 Therapeutic composition for bone infectious disease  
A biodegradable composition containing an antibiotic or a physiologically active substance for use in surgical treatment of infection. A highly safe and biocompatible composition showing...
US20090280094 Treatment of Ischemic Diseases Using Erythropoietin  
Disclosed is a method for stimulating revascularization in a subject comprising the steps of: (a) administering erythropoietin to the subject;(b) collecting peripheral blood mononuclear cells from...
US20090143287 TISSUE REGENERATION SUBSTRATE  
The present invention provides a tissue regeneration substrate that has the ability to release a basic fibroblast growth factor (bFGF) and like cell growth factors in a sustained manner, into...
US20140322351 BIOFILM-REMOVING ANTIMICROBIAL COMPOSITIONS AND USES THEREOF  
The present invention provides novel compositions comprising: (a) a metaperiodate and (b) chlorhexidine or a chlorohexidine salt and uses thereof for the preparation of devices, and in particular...
US20090220595 COMBINATION OF ERYTHROPOIETIN GLYCOISOFORMS  
This invention relates to a combination of erythropoietin glycoisoforms, wherein such glycoisoforms may include a quantity of sialic acid ranging from 4 to 10 molecules of sialic acid per molecule...
US20090036368 Therapeutic Combination  
A combination of component (i) which is HAMLET or a biologically active modification thereof, or a biologically active fragment of either of these, and component (ii) which is a histone...
US20070191264 Methods for inhibiting the growth of bacteria  
The present invention is directed to a novel method for inhibiting the growth of bacterial pathogens expressing a type III secretory system as well as enteroaggregative E. coli and/or preventing...
US20060233777 Use of bacteriocin for the amelioration of digestive functionality  
The subject of the present invention is the use of bacteriocins and/or their producer strains for the amelioration of digestive functionality and for the amelioration of gastrointestinal tract...
US20100008973 Compositions And Methods For Wound Healing  
The present invention is related to the field of wound healing or tissue regeneration due to disease (i.e., for example, cardiovascular diseases, osteoarthritic diseases, or diabetes). In...
US20120318262 Pyrvinium Wound Treatment Methods and Devices  
The present invention concerns a pyrvinium compound or salt or an analog thereof for the treatment of wounds. The present invention also concerns devices for delivering a pyrvinium compound or...
US20150158931 CYSTEINE PROTEASE CAPTURING AGENTS  
The invention concerns cysteine protease capturing agents capable of highly selective and irreversible binding of the corresponding cysteine protease. Such compounds may have utility in...
US20090104149 Compositions For HCV Treatment  
The present invention concerns a pharmaceutical combination comprising a) a first agent which is a non-immunosuppressive cyclophilin-binding cyclosporin, e.g. a compound of formula I and b) a...
US20070190064 Enteral composition for the prevention and/or treatment of sepis  
Enteral compositions and use thereof, which compositions contain proteins and lipids, for the prevention and/or treatment of sepsis; the lipid fraction being particularly rich in phospholipids.
US20100203103 THERAPEUTIC COMPOSITIONS FOR TREATMENT OF INFLAMMATION OF OCULAR AND ADNEXAL TISSUES  
The present invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-1 and methods for using this composition to treat inflammatory disease of ocular...
US20090035270 COMBINATION THERAPY USING ANTI-ANGIOGENIC AGENTS AND TNF alpha  
The invention relates to a combination therapy for the treatment of tumors metastases comprising administration of anti-angiogenic agents and rumor necrosis factor alpha (TNFa) optionally together...
US20150209408 GLYCAN COMPOSITIONS, PROCESSES FOR PREPARING THE SAME AND THEIR USES AS A DRUG  
Glycan compositions, processes for preparing the same and their uses as a drug.
US20060150262 Novel mucin-like polypeptides  
The present invention discloses open reading frame (ORFs) in human genome encoding for novel mucin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said...
US20070104783 Double-Layered Absorbable Solid Compositions for the Topical Treatment of Oral Mucosal Disorders  
Bioadhesive sticker tablets which are applied directly to vaginal, rectal and/or oral mucosa are described herein. In one embodiment, the sticker tablets are applied directly to ulcers or lesions...
US20100254940 Compositions and Methods for Regulating an Immune Response in a Subject  
The present invention relates to compositions an methods for regulating an immune response in a subject, particularly to treat a subject with a tumor, notably a solid tumor, or an infectious...
US20090162439 SILK FIBROIN COATING  
The present invention is directed to compositions and methods for preventing or inhibiting biofilm formation on a solid substrate comprising an antimicrobial agent and a biofilm-degrading enzyme...
US20080262415 ENHANCED WOUND HEALING  
A method comprising non-systemic localized administration of a pharmaceutically acceptable formulation and effective concentration of at least one neurostimulatory and/or neuroprotective macrolide...
US20090068103 APTAMERS LABELED WITH 68GA  
This invention relates to novel nucleotide-based compounds, methods of making radiolabeled compounds and use of such compounds for diagnostic imaging. Provided are compounds according to Formula...
US20110230393 Antibacterial Phage Peptides and Methods of Use thereof  
The present invention is directed to isolated and chimeric polypeptides of bacteriophage origin having antibiotic activity and use thereof in the treatment and control of bacterial infections....
US20140148380 MOLECULAR ROADBLOCKS FOR RpoN BINDING SITES  
The present invention relates to, inter alia, a method for repressing transcription and/or gene expression from RpoN binding sites (or promoters) or cryptic promoters upstream of RpoN binding...
US20080241143 Inhibition of leukocyte adhesion  
This invention relates to the inhibition of intercellular adhesion mediated by L-selectin by administering a newly identified L-selectin ligand, CD34. More particularly, the invention concerns a...
US20070020336 Cyclodextrin nanotechnology for ophthalmic drug delivery  
The invention provides an ophthalmic composition which is an aqueous suspension comprising drug, cyclodextrin and water, the composition having an aqueous phase of from about 0.1% (w/v) to about...
US20070292496 Formulation of liposomal vesicles in aqueous solutions with lachrymal film characteristics  
The present invention involves the preparation of a pharmaceutical liposomal system in an aqueous solution which contains a substance or polymer with mucomimetic and/or mucoadhesive properties....
US20090181102 PROCESS FOR OBTAINING HIGH EFFICIENCY HUMAN ALBUMIN FOR USE IN DETOXIFICATION THERAPY  
A process for purifying and collecting albumin from plasma and plasma fractions involves diafiltration of an albumin-containing plasma fraction; stabilizing the resulting albumin fraction with...
US20070093410 Selective inhibition of proteasomes of tuberculosis and other bacteria  
Compositions and methods for inhibiting bacterial proteasomes are provided. Methods of screening antibacterial compounds, methods of treating bacterial infections and disorders associated with...
US20090297473 Sulphonylpyrrole Hydrochloride Salts as Histone Deacetylases Inhibitors  
Compounds of a certain formula 1, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
US20050019342 Lactoferrin as an adjuvant in cancer vaccines  
The present invention relates to methods of treating cancer by administering a composition of lactoferrin (LF) in combination with cancer vaccines.
US20130252882 ANTIMICROBIAL 4-OXOQUINOLIZINES  
This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In...
US20060229244 Engineered bacteriocins and bacteriocin combinations and methods for treating bacterial based infections  
A method for treating bacterial infections in a patient is provided. The method includes the step of administering a therapeutically effective amount of a single naturally-occurring or engineered...
US20140066363 CARBOHYDRATE NANOPARTICLES FOR PROLONGED EFFICACY OF ANTIMICROBIAL PEPTIDE  
A nanoparticle includes a carbohydrate carrier and a bacteriocin. A method for prolonging efficacy of a bacteriocin against a food pathogen includes providing the bacteriocin in a delivery system,...
US20130184200 Immunogenic Polypeptides and Monoclonal Antibodies  
Provided herein are compositions and methods for eliciting an immune response against Streptococcus pneumoniae. More particularly, the compositions and methods relate to immunogenic polypeptides,...
US20100093614 Novel Composition for Tumor Growth Control  
The invention describes a pharmaceutical composition comprising at least compound selected from the group of demethylating agents and HDAC inhibitors and at least one somatostatin analog or...