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US20150141325 IDENTIFICATION OF INHIBITORS OF A BACTERIAL STRESS RESPONSE  
A system, a composition, a method and a kit for identifying anti-bacterial agents are provided. The invention described herein is useful in identifying inhibitors of any bacterial stress response....
US20120157375 Identification of Inhibitors of a Bacterial Stress Response  
A system, a composition, a method and a kit for identifying anti-bacterial agents are provided. The invention described herein is useful in identifying inhibitors of any bacterial stress response....
US20050180922 Block co-polymer worm micelles and methods of use therefor  
Provided are worm-like micelles, capable of encapsulating at least one encapsulant, wherein each worm-like micelle comprises one or more wholly synthetic, polymeric, super-amphiphilic molecules...
US20060008466 Methods for treating and preventing microbial infections  
Methods for the treatment and prevention of microbial infection, such as infections caused by bacteria, viruses, fungi and parasites are disclosed, as are adjuvants for use with vaccines against...
US20150126432 V1a Receptor Agonists  
Compounds of formula (I), salts thereof, and compositions and uses thereof are described. The compounds are useful as V1a vasopressin agonists, for the treatment of e.g., complications of...
US20060111283 Prevention therapy and prognosis/monitoring in sepsis and septic shock  
The invention relates to the use of a peptide which binds to lipopolysaccharide (LPS) or lipoteichoic acid (LTA), for manufacturing a pharmaceutical composition for treating sepsis or septic...
US20080118463 Light Pharmaceutical Water and Therapeutic Compositions and Methods Thereof  
This invention relates to pharmaceutical water, which comprises from 99.760 to 99.999% of light isotopologue 1H2 16O and up to 100% of residual isotopologues 1H2 17O, 1H2 18O, 1H2H16O, 1H2H17O,...
US20130267458 COMPOSITIONS AND USES OF MATERIALS WITH HIGH ANTIMICROBIAL ACTIVITY AND LOW TOXICITY  
Improved synthetic copolypeptide antimicrobials contain cationic amino acid residues and may be based on a blocky sequence. These antimicrobials show low mammalian toxicity and may undergo...
US20110065630 USE OF A OCTREOTIDE AS A THERAPEUTIC AGENT  
The present invention is directed to the use of the peptide compound D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune...
US20110118174 TREATMENT SOLUTION AND METHOD FOR PREVENTING POSTERIOR CAPSULAR OPACIFICATION BY SELECTIVELY INDUCING DETACHMENT AND/OR DEATH OF LENS EPITHELIAL CELLS  
A treatment solution used to prevent posterior capsular opacification is applied or introduced into the lens capsular bag before, during, or after cataract surgery. The treatment solution may also...
US20100144619 Antimicrobial Protein Specific to Staphylococcus Aureus  
The present invention relates to a novel bacteriophage-originated protein having antimicrobial activity, more precisely an antimicrobial protein originated from lytic bacteriophage having killing...
US20140073558 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS  
The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the...
US20100216700 METHODS OF TREATING OCULAR DISORDERS  
This invention is directed to treatments of ocular disorders using emulsions and molecular dispersions in the form of a gel comprising a hydrophobic ocular agent.
US20050233974 Treating infectious diseases using ice inhibitors  
This invention relates to methods and compositions for treating infectious and other diseases, particularly of the eye, by administering an ICE inhibitor. This invention also relates to methods...
US20140024576 HEPTOSE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS  
Compounds having the general formula (I) pharmaceutical compositions containing them for use in inhibiting bacterial heptose biosynthesis and thereby lowering or suppressing bacterial virulence.
US20090214538 USE OF COMPLEMENT INHIBITORS TO TREAT OCULAR DISEASES  
The present invention relates to the treatment of ocular diseases and conditions by administering a complement pathway inhibitor, particularly an alternative pathway inhibitor Ocular diseases...
US20080194493 Compositions Containing D-Carnosine  
Disclosed are compositions containing D-carnosine as active ingredient, mixed with suitable vehicles or excipients.
US20140094401 MITRECIN A POLYPEPTIDE WITH ANTIMICROBIAL ACTIVITY  
The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria...
US20120214731 COMPOUND WS 727713  
The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of...
US20070218001 Biotherapeutics, Diagnostics and Research Reagents  
The present invention provides polypeptides that contain one or more PDZ domains and are useful in the detection of pathogens. The polypeptides of the invention are also useful in the diagnosis,...
US20130039885 LEUKOTOXIN E/D AS A NEW ANTI-INFLAMMATORY AGENT AND MICROBICIDE  
The present invention relates to methods for preventing or treating Human Immunodeficiency Virus (HIV) infection, inflammatory conditions, and graft-versus-host-disease (GVHD) in a subject....
US20080089923 Biodegradable ocular implants and methods for treating ocular conditions  
Biodegradable ocular implants are described. The ocular implants include a bioactive agent that can be released within the eye to treat an ocular condition or indication. The implants can be used...
US20060234927 Neuroprotective iron chelators and pharmaceutical compositions comprising them  
Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload...
US20100166777 HEMATOPOIETIC CELLS THAT EXPRESS MOSC-1  
The present invention relates to ex-vivo cells belonging to the hematopoietic system, characterized by the presence of MOSC-1 protein on cell surface, methods for isolating them and uses thereof.
US20100227810 METHOD FOR DIAGNOSING STAPHYLOCOCCAL INFECTIONS  
The present invention relates to a method for determining if an individual is infected by a staphylococcus bacterium, comprising: determining if antibodies directed against at least 2 proteins...
US20150202257 METHODS AND COMPOSITIONS FOR METABOLIC REGULATION  
The invention relates, in part, to methods and compositions that are useful to modulate metabolic function of cells in vivo or in vitro. In some aspects the invention includes methods and/or...
US20100041607 UNCTUOUS COMPOSITIONS  
The present invention relates to unctuous composition containing at least one solid active ingredient, at least one hydrophobic protective colloid and at least one edible oil. The active...
US20120328635 CHAPERONIN 10 VARIANTS  
The invention relates generally to chaperonin 10 N-terminal variants. More specifically, the invention relates to chaperonin 10 N-terminal variants with enhanced immunomodulatory capacity and/or...
US20060134186 Oxygenating agents for enhancing host responses to microbial infections  
Oxygenating agents are used in the present invention for the novel purpose of treating microbial infections. The invention takes advantage of the fact that the increase in tissue pO2 produced...
US20120172286 THERAPEUTIC USE FOR ALPHA1 PROTEINASE INHIBITOR IN HEMATOPOIESIS  
A previously unrecognized fundamental property of α1PI is to regulate the phenotypic composition of circulating and tissue-associated cells derived from hematopoietic stem cells. The present...
US20060264353 Prostaglandin f2alpha analogs and their use in combination with antimicrobial proteins for the treatment of glaucoma and intraocular hypertension  
An ophthalmic formulation for the treatment of glaucoma and intraocular pressure with a prostaglandin compound of the F-series (PGF), and particularly a prodrug form of a PGF2α analog, such as an...
US20120202736 SPRAY-DRIED COLLECTIN COMPOSITIONS AND PROCESS FOR PREPARING THE SAME  
The present invention relates to a spray-dried composition comprising as an active ingredient at least one member protein of the collectin family or its functional equivalent for treating and...
US20070110758 Method for inhibiting bacterial colonisation  
The present invention relates to a method for inhibiting bacterial colonisation of mucous epithelium in a biological system. The method includes the step of administering to the biological system...
US20140302095 MYCOBACTERIUM TUBERCULOSIS PORINS AND TOXINS AND RELATED METHODS  
Provided herein are isolated polypeptides comprising the amino-terminal domain of Mycobacterium tuberculosis porin A (MtpA), wherein the polypeptide is a porin monomer. Also provided are isolated...
US20110008304 USE OF CELLS TO FACILITATE TARGETED DELIVERY OF NANOPARTICLE THERAPIES  
The present invention is related to the use of cells, such as stem cells or immune system cells, to deliver nanogels comprising an active agent to a desired site in the body. The present invention...
US20150246027 FIXED DOSE PHARMACEUTICAL COMPOSITION COMPRISING DEFERASIROX AND DEFERIPRONE  
The present invention relates to a fixed dose pharmaceutical composition comprising iron chelating agents.
US20070298051 Adjuvants Of Immune Response  
The present invention features methods to substantially increase the immunogenicity of a vaccine, preferably a DNA vaccine, and involves providing a mammal with a vaccine regimen, which includes...
US20080082038 Medical Device including a Bioactive in a Non-ionic and an Ionic Form and Methods of Preparation Thereof  
A medical device having a bioactive in a salt and a free-base form contained within the device and/or coated onto a surface of the device. The salt and the free-base form have different...
US20070065527 Activated citrus peel extract  
The present invention relates to composition comprising an activated citrus peel extract (ACPE) prepared by an activation method which includes exposure of citrus peels to at least one plant or...
US20100041613 NOVEL ANTIBIOTIC COMPOSITIONS  
This invention is directed to antibiotic compositions comprising a targeting moiety covalently linked to an antibiotic moiety. This invention is also directed to pharmaceutical compositions...
US20050180973 TREM-1 splice variant for use in modifying immune responses  
The present invention relates to a soluble receptor variant of TREM-1. More particularly, present invention relates to methods of modulating an immune response by administering variants of TREM-1.
US20090247469 OPHTHALMIC COMPOSITIONS COMPRISING A DIPEPTIDE  
An ophthalmic composition comprising one or more antimicrobial components and a dipeptide. The dipeptide comprises a glycine moiety and another amino acid moiety other than glycine. The ophthalmic...
US20130129682 HAEMOPHILUS PARASUIS POLYPEPTIDES AND METHODS OF USE  
The present invention provides isolated polypeptides having oligopeptide permease activity and an amino acid sequence that has at least 80% identity with a Haemophilus parasuis OppA polypeptide....
US20100297179 Immunology Treatment for Biofilms  
The invention provides a composition for use in raising an immune response to P. gingivalis in a subject, the composition comprising an amount effective to raise an immune response of at least one...
US20140186278 ANHYDROUS MULTIPHASE GEL SYSTEM  
An anhydrous multiphase gel system consisting of an outer lipid matrix and an inner phase gelled by means of a polymer is described, which can be obtained by a) Melting the lipid phase with the...
US20070213382 2-METHYLTHIAZOLIDINE-2, 4-DICARBOXYLIC ACID-CONTAINING COMBINATION PREPARATIONS  
The invention relates to a combination preparation of 2-methylthiazolidine-2,4-dicarboxylic acid and/or physiologically acceptable salts thereof and at least one cytotoxic and/or cytostatic...
US20080181889 PREVENTION OF CHLAMYDIA INFECTION USING A PROTECTIVE ANTIBODY  
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections. The methods and compositions inhibit the entry of Chlamydia into a host cell...
US20080213175 Click chemistry-derived cyclic peptidomimetics as integrin markers  
The present application is directed to radiolabeled cyclic peptidomimetics, pharmaceutical compositions comprising radiolabeled cyclic peptidomimetics, and methods of using the radiolabeled cyclic...
US20100203180 Antimicrobial protein derived from podoviriedae bacteriophage specific to staphylococcus aureus  
The present invention relates to a novel antimicrobial protein derived from bacteriophage having killing activity specific to Staphylococcus aureus, more precisely an antimicrobial protein...
US20050287180 Phospholipid compositions and methods for their preparation and use  
The present invention provides compositions that comprise a phospholipid component (that contains one or more phospholipids) and a pharmaceutically acceptable fluid carrier, where the phospholipid...