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US20110212162 |
LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS
Disclosed herein are compositions and methods for and involving selectively targeting tumor lymphatics.
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US20100317590 |
REGULATION OF SKIN CHARACTERISTICS BY DICKKOPF1 (DKK1)
The present disclosure is generally related to methods of inducing non-palmoplantar skin to develop a palmoplantar phenotype, for example, methods for increasing skin thickness, decreasing skin...
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US20120100106 |
COLLAGEN-BINDING SYNTHETIC PEPTIDOGLYCANS FOR WOUND HEALING
Methods and compositions for promoting wound healing in a patient by administering a collagen-binding synthetic peptidoglycan to the patient are described. Additionally, methods and compositions...
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US20110212157 |
DERMAL DELIVERY
The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis,...
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US20120252735 |
TREATMENT OF SKIN CONDITIONS BY DICKKOPF1 (DKK1)
The present disclosure is generally related to methods of inducing non-palmoplantar skin to develop a palmoplantar phenotype, for example, methods for increasing skin thickness, decreasing skin...
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US20110301090 |
SKIN WOUND HEALING COMPOSITIONS AND METHODS OF USE THEREOF
A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either...
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US20110086805 |
IN VITRO METHOD FOR DIAGNOSING SKIN CANCER
The present invention relates to an in vitro method for identifying an individual suffering from or having a predisposition to skin cancer, characterized in that it comprises the step of analysing...
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US20130045918 |
Methods for Treating Diabetic Wounds
The present invention relates to a method of treating chronic wounds using calreticulin. In particular, the invention relates to the treatment of chronic diabetic wounds using topical application...
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US20110166076 |
Antigen-binding proteins that inhibit superantigens for the treatment of skin diseases
The present invention relates to superantigen-specificantigen-binding proteins comprising an immunoglobulin-derived variable domain that comprises a complete antigen binding site for an epitope on...
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US20110027364 |
BIOACTIVE AND RESORBABLE SOYBEAN-BASED BIOMATERIALS
A method of producing a soybean-based biomaterial which is suitable for use in a biomedical product, the method comprising: defatting soy flour; either prior to or at the same time as, performing a...
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US20110294731 |
SKIN CREAM
Preferred embodiments of the invention relate to compositions, including anti-aging cosmeceuticals for topical application, and more particularly, a skin cream, comprising cell culture medium...
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US20110256130 |
METHODS OF TREATING INFLAMMATORY DISORDERS
Disclosed herein, in certain embodiments, are methods and compositions for treating inflammatory disorders. In some embodiments, the methods comprise co-administering synergistic combinations of...
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US20110008455 |
Crosslinked Protein Nanocrystals, Crosslinked Protein Nanoaggregates and Method of Preparation Thereof
This invention relates to crosslinked protein nanoparticles and a method for producing the same. The method comprises the preparation and nanonization (i.e., size reduction to the nanoscale) of...
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US20130065835 |
PROGNOSTIC TESTS FOR DEVELOPMENT OF DERMAL STRETCH MARKS AND IMPLICATIONS FOR THE PREVENTATIVE TREATMENT THEREOF
Various methods of assessing the regenerative potential of dermal tissue in a patient may be determined and methods to determine the potential development of stretch marks in a patient are...
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US20110172153 |
SCREENING METHODS USING G-PROTEIN COUPLED RECEPTORS AND RELATED COMPOSITIONS
The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a...
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US20120027705 |
ADMINISTRATION OF CELLS AND CELLULAR EXTRACTS FOR REJUVENATION
The invention describes methods and agents for improving cosmetic appearance, for promoting, improving or restoring health of cells and tissues, preferably skin, and more preferably, for restoring...
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US20110305634 |
Methods and systems for adenovirus interaction with desmoglein 2 (DSG2)
The present invention provides compositions and methods for treating disorders associated with epithelial tissues.
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US20110070237 |
METHODS OF MODULATING AND IDENTIFYING AGENTS THAT MODULATE INTRACELLULAR CALCIUM
Methods are provided for identifying agents that modulate intracellular calcium. Also provided are methods of modulating calcium within cells and methods of identifying proteins involved in...
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US20110124569 |
MACROCYCLIC COMPOUNDS, PROTEASE INHIBITION, AND METHODS OF TREATMENT
The instant invention describes macrocyclic depsipeptide lyngbyastatins, and methods of treating disorders such as COPD, emphysema, rheumatoid arthritis, and aging related disorders.
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US20120058086 |
COMPOSITIONS, KITS, AND METHODS FOR PROMOTING ISCHEMIC AND DIABETIC WOUND HEALING
Compositions, kits and methods for promoting diabetic wound healing are based on the discovery that SDF-1α specifically upregulates expression of E-selectin in mature endothelial cells (EC), ...
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US20120142605 |
METHODS OF TREATING PSORIASIS
The invention includes methods for treating patients having psoriasis and methods for testing the efficacy of such treatments. The methods include treating the patients with a TNF inhibitor plus a...
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US20120077750 |
USE OF A GROWTH-STIMULATING PROTEIN
This invention relates to the inhibition of a newly discovered growth-stimulating protein in an individual. Further, the invention relates to a method for preventing or treating a cancer, or...
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US20110301091 |
COMPOSITIONS AND METHODS FOR REDUCING THE SIGNS OF AGING OF THE SKIN
Compositions and methods used to reduce the visible signs of aging of the skin by recalibrating the expression of genes, genetic networks, and cellular pathways in the human skin, particularly...
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US20120135937 |
INJECTABLE COMBINATION OF ADRENERGIC RECEPTOR AGONISTS WITH FILLERS, FOR DECREASING SKIN REACTIONS DUE TO INJECTION
The present invention concerns an injectable composition comprising a filler or a botulinum toxin and an adrenergic receptor agonist, and its use for diminishing, decreasing or avoiding skin...
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US20110028404 |
Composition Comprising Vegetable Peptone for Promoting Stem Cell Proliferation
The present invention relates to a composition for promoting stem cell proliferation which contains a vegetable peptone. More specifically, this invention relates to: a serum-free composition for...
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US20130072445 |
DEVELOPMENT OF C-REACTIVE PROTEIN MUTANT WITH IMPROVED THERAPEUTIC BENEFIT IN IMMUNE THROMBOCYTOPENIA AND LUPUS NEPHRITIS
The present invention relates to the use of a mutant CRP molecule in which tyrosine 175 is replaced by leucine (Y175L CRP) or the leucine 176 is replaced by glutamic acid (L176E CRP) for the...
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US20110152202 |
DEVELOPMENT OF C-REACTIVE PROTEIN MUTANT WITH IMPROVED THERAPEUTIC BENEFIT IN IMMUNE THROMBOCYTOPENIA AND LUPUS NEPHRITIS
The present invention relates to the use of a mutant CRP molecule in which tyrosine 175 is replaced by leucine (Y175L CRP) or the leucine 176 is replaced by glutamic acid (L176E CRP) for the...
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US20110059173 |
COMPOSITIONS AND METHODS FOR PROMOTING WOUND HEALING AND TISSUE REGENERATION
Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.
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US20110081401 |
DERMAL PATCH COMPRISING CHONDRUS CRISPUS EXTRACT
The present invention relates to masks for dermal treatment or “patches”, based on a vegetal matrix, particularly red algae (Chondrus crispus) extract rich in polymeric thickeners. The inv...
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US20110288031 |
IDENTIFICATION OF A NOVEL BHD GENE
The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and methods of using the nucleic acids and proteins encoded thereby. In particular, the present ...
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US20110311529 |
METHOD FOR TREATING A RHEUMATIC DISEASE USING A SOLUBLE TLA4 MOLECULE
The present invention relates to compositions and methods for treating rheumatic diseases, such as psoriasis arthropathica, by administering to a subject a CTLA4 molecule that block endogenous B7...
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US20120238500 |
REGULATION OF EPITHELIAL TISSUE BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO
The present application is directed to the discovery that preparations of hedgehog polypeptides can be used to control the formation and/or maintenance of epithelial tissue.
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US20120184493 |
DERMAL FORMULATIONS OF DP2 RECEPTOR ANTAGONISTS
Described herein are topical formulations for use in the treatment or prevention of dermatological diseases, disorders, or conditions in a mammal. Topical formulations disclosed herein include a...
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US20100311645 |
PROTEINS FROM THE WEBS OF NEPHILENGYS CRUENTATA, AVICULARIA JURUENSIS AND PARAWIXIA BISTRIATA SPIDERS ISOLATED FROM BRAZILIAN BIODIVERSITY
The Present invention relates to molecules isolated from the nucleic acid that encodes spider web proteins or fragments of these or other derivatives of these. The invention also refers to a...
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US20120238506 |
ACACIA MACROSTACHYA SEED EXTRACT AND COMPOSITIONS CONTAINING SAME
The invention relates to a composition containing an extract of seeds of Acacia macrostachya. Advantageously the composition is cosmetic, pharmaceutical, dermatological or nutraceutical. The...
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US20110059885 |
TREATMENT OF DISEASES AND CONDITIONS MEDIATED BY EICOSANOIDS
The method of the invention relates to an OmCI polypeptide or a polynucleotide encoding an OmCI polypeptide for the treatment of a disease or condition mediated by a leukotriene or hydroxyeicosanoid.
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US20110230417 |
TREATMENT OF DISEASES AND CONDITIONS MEDIATED BY INCREASED PHOSPHORYLATION
The invention provides methods for the treatment of diseases and conditions mediated by increased phosphorylation, such as inflammation and cancer. The invention also provides methods for the...
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US20120107412 |
USE OF CELLULAR EXTRACTS FOR SKIN REJUVENATION
The invention describes methods and agents for improving cosmetic appearance, for promoting, improving or restoring health of cells and tissues, preferably skin, and more preferably, for restoring...
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US20060088497 |
Topical skin care composition
A topical skin care product formula having a beneficial effect on the user's face and/or neck skin and appearance. The formula can be used for preparation of a skin cream and/or skin serum to be...
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US20110028403 |
HSP70-Based Treatment for Autoimmune Diseases and Cancer
A non-natural HSP70 activating region that activates dendritic cells. Polypeptides that bind to the HSP70 activating region can be used to treat autoimmune diseases, such as vitiligo, by binding to...
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US20110218143 |
COMPOSITIONS AND METHODS FOR TISSUE REPAIR
The invention generally provides compositions and methods for the repair or regeneration of a tissue or organ in need thereof.
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US20110269691 |
Compositions and Methods for Treating Pigmentary Conditions and Melanoma
A method of treating a hypopigmentary condition in a subject comprising administering to the subject an amount of SOX9 sufficient to treat melanoma is disclosed. The hypopigmentary condition can be...
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US20130108602 |
METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE
Methods of decreasing, reducing, inhibiting, suppressing, limiting or controlling an undesirable or aberrant immune response, immune disorder, inflammatory response, or inflammation in a subject;...
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US20110020375 |
STROMAL CELL-DERIVED FACTOR-1 POLYPEPTIDES, POLYNUCLEOTIDES, MODULATORS THEREOF AND METHODS OF USE
Disclosed herein is a newly identified SDF-1 splice variant molecule, its polypeptide sequence, and the polynucleotides encoding the polypeptide sequence, and active fragments thereof. Also...
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US20110142833 |
METHODS FOR TREATING AND PREVENTING FIBROSIS
The present invention provides methods of screening for compositions useful for treating, ameliorating, or preventing fibrosis and/or fibrosis-associated conditions by measuring changes in the...
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US20130034523 |
USE OF SDF-1 TO MITIGATE SCAR FORMATION
The subject matter provided herein relates to method for inhibiting or mitigating scar formation in a wound of the skin, by increasing the concentration of SDF-1 in, or proximate to, the wound. As...
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US20110142819 |
METHOD OF IMPROVING WOULD HEALING
This invention relates to novel methods of promoting the healing or closure of perforated tympanic membranes or wounds, as well as methods for minimizing scar formation and removing necrotic...
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US20130039903 |
ECZEMA TREATMENT
A use of a composition including lactoferrin and/or immunoglobulin for minimizing the severity of one or more symptoms associated with eczema.
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US20120213843 |
COMPOSITION FOR PROMOTING WOUND HEALING
A lipid layer forming wound healing promoting composition comprising volatile silicone oil, polar lipid, C2-C4 aliphatic alcohol, and a wound healing agent, in particular a low to medium size...
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US20120276126 |
LACTOFERRIN IN THE TREATMENT OF MALIGNANT NEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES
The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
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