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US20090285893 |
TREATMENT OF HEART FAILURE IN WOMEN
A method is disclosed utilizing an androgen such as testosterone and/or a selective androgen receptor modulator for treating or delaying the further development of heart failure, and other...
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US20090280067 |
CRYSTAL FORM OF 8-HYDROXY-5-[(1R)-1-HYDROXY-2-[[(1R)-2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO]ETHYL]-2(1H)-QUINOLINONE MONOHYDROCHLORIDE
Crystal form E of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-m
ethylethyl]-amino]ethyl]-2(1H)-quinolinone monohydrochloride is highly crystalline, easy to prepare, and stable.
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US20090269394 |
METHODS AND COMPOSITIONS FOR TREATING ONCHOMYCOSIS
The present invention relates to methods for treating and completely curing fungal, yeast and/or mold infections in human subjects comprising topically administering to a human subject in need...
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US20090264385 |
STABILIZED COMPOSITIONS CONTAINING ALKALINE LABILE DRUGS
A stabilized bioadhesive composition containing an alkaline labile drug and a method for its preparation are provided. In one aspect, the composition is a hot-melt extruded (HME) composition...
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US20090258075 |
Respiratory Drug Condensation Aerosols and Methods of Making and Using Them
Described herein are respiratory drug condensation aerosols and methods of making and using them. Kits for delivering condensation aerosols are also described. The respiratory drug aerosols...
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US20090258062 |
Transdermal Therapeutic System Comprising Active Ingredient Particles and Having Increased Active Ingredient Flux
The invention relates to a transdermal therapeutic system, preferably a transdermal patch, having an active ingredient-containing matrix formed substantially of a water-insoluble base material,...
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US20090258040 |
STEROID TREATMENT FOR HOT FLASHES
Embodiments of the invention relate to methods for treating individuals suffering from hot flashes by vomeronasally administering a therapeutically effective dosage of a steroid agent. The hot...
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US20090247495 |
CUCURBITACIN B AND USES THEREOF
The present invention relates to uses of cucurbitacins and compositions comprising cucurbitacin B. The present invention also relates to methods for preventing or treating various diseases and...
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US20090239835 |
STABILIZATION OF GLUCOCORTICOID ESTERS WITH ACIDS
The invention relates to nonaqueous pharmaceutical preparations comprising a glucocorticoid ester and an acid, and to the stabilization of glucocorticoid esters in such preparations by acids.
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US20090233891 |
Pharmaceutical lotion comprising fluticasone propionate
The present invention generally relates to a pharmaceutical composition. More particularly, the present invention relates to a stable topical lotion comprising at least a therapeutically effective...
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US20090232865 |
End-Capped Poly(Ester Amide) Copolymers
This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of...
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US20090220602 |
SUBLIMABLE SUSTAINED RELEASE DELIVERY SYSTEM AND METHOD OF MAKING SAME
The invention relates to compositions suitable for the delivery and/or stabilization of biologically active substances. The compositions comprise a sublimable matrix material and the biologically...
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US20090220583 |
Method and composition for treating inflammatory disorders
There is provided homogeneous pharmaceutical compositions for the treatment of inflammatory disorders comprising an antiinflammatory and/or antihistaminic active ingredient, a polar lipid liposome...
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US20090216317 |
Delivery of Highly Lipophilic Agents Via Medical Devices
An apparatus and system for delivering a lipophilic agent associated with a medical device including: a medical device, a first lipophilic agent capable of penetrating a body lumen, wherein the...
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US20090215738 |
PREVENTION AND TREATMENT OF AN INCREASE IN CARDIOVASCULAR RISK, ADVERSE CARDIOVASCULAR EVENTS, INFERTILITY, AND ADVERSE PSYCHOLOGICAL EFFECTS AFTER ANDROGEN OR GNRH ANALOGUE INTAKE
Disclosed is a is a treatment for the adverse psychological effects (including depression, low self esteem, guilt, increased stress, anhedonia, decreased cognition, sleep disturbances, general...
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US20090215737 |
Pharmaceutical Compositions - 2
The invention provides compositions comprising formula 1 steroids, e.g., 16α-bromo-3β-hydroxy-5α-androstan-17-one hemihydrate and one or more excipients, typically wherein the composition...
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US20090192130 |
Method for Treating Uterine Fibroids
The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of...
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US20090163458 |
Compositions and methods for treating Parkinson's disease and related disorders
The present disclosure relates generally to methods and compositions for treating symptoms of Parkinson's disease and/or other movement disorders. More particularly, the present disclosure...
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US20090156569 |
ORAL CONTRACEPTIVE SPRAY
The subject invention provides a liquid contraceptive formulation for oral transmucosal administration. The formulation comprises etonogestrel, optionally together with ethinyl estradiol but does...
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US20090156564 |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR RELIABLE ACHIEVEMENT OF ACCEPTABLE SERUM TESTOSTERONE LEVELS
Described are methods for providing prolonged physiologically acceptable steady state serum testosterone levels in a patient deficient in endogenous testosterone levels, methods for male...
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US20090155326 |
LAYERED DRUG DELIVERY POLYMER MONOFILAMENT FIBERS
The present invention is directed generally to a layered polymeric monofilament fiber drug delivery device, where each layer of the device can contain a different polymer, drug, additive, or any...
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US20090143343 |
COMPOSITIONS FOR THE TREATMENT OF INFLAMMATION OF THE GASTROINTESTINAL TRACT
Provided herein are methods for treating the symptoms of and inflammation associated with gastroesophageal reflux disease (GERD) and other conditions. Also provided herein are pharmaceutical...
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US20090137542 |
Alpha-glucosidase inhibitors from fungal hydroxylation of tibolone and hydroxytibolones
Sixteen new and one known metabolites were obtained by incubation of tibolone and hydroxytibolones with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR...
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US20090137540 |
COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL INFLAMMATION
Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example,...
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US20090131385 |
Estriol Therapy for Autoimmune and Neurodegenerative Diseases and Disorders
The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, neurodegenerative diseases or disorders, such as Alzheimer's disease, Parkinson's...
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US20090124588 |
Androstane 17-Alpha-Carbonate for Use in the Treatment of Inflammatory and Allergic Conditions
The present invention is directed to compounds of formula (I):
wherein
R 1 represents a 1,1-dimethylethyl group or a 1,1-dimethylpropyl group and physiologically acceptable solvates thereof,...
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US20090118702 |
Treatment Medium Delivery Device and Methods for Delivery of Such Treatment Mediums to the Eye Using such a Delivery Device
Featured are devices for delivering a treatment medium to an eye as well as methods related thereto. Such devices and methods allow a desired amount of the treatment medium to be delivered in a...
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US20090118249 |
DHEAS INHALATION COMPOSITIONS
The present invention provides compositions for aqueous suspension comprising DHEAS and a divalent cation. The suspension in combination with a nebulizer or nasal pump spray can be administers as...
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US20090117155 |
TREATMENT OF HIV-1 BY MODULATION OF VPR ACTIVATION OF THE M-CSF PROMOTER
Macrophage colony-stimulating factor (M-CSF) is important for human immunodeficiency virus-type 1 (HIV-1) infection, replication and survival of infected cells. The mechanism(s) by which HIV-1...
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US20090111787 |
Polymer blends for drug delivery stent matrix with improved thermal stability
Various embodiments of the present invention generally relate to a polymer blend composition used for coating a medical device that exhibits improved thermal stability. The invention also...
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US20090110735 |
CONTROLLED RELEASE FORMULATIONS
The present invention provides stable, self-assembling, biocompatible and biodegradable hydrogel formulations, into which one or more compounds may be incorporated allowing for delayed release or...
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US20090110731 |
Loadable Polymeric Microparticles for Therapeutic Use in Alopecia and Methods of Preparing and Using the Same
Particles are provided for use in restorative procedures to treat and/or retard alopecia The particles include poly[bis(trifluoroethoxy)phosphazene] and/or a derivatives thereof which may be...
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US20090110711 |
IMPLANTABLE DEVICE HAVING A SLOW DISSOLVING POLYMER
The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
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US20090105202 |
Androsterone Derivatives and Method of Use thereof
The disclosure provides androsterone derivatives. The derivatives of the disclosure are useful in the treatment of androgen- and estrogen-associated diseases and disorders, including breast cancer.
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US20090105198 |
NOVEL ESTROGENIC COMPOUNDS
Novel estrogenic compounds of Formula I are provided.
wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R 1 is selected...
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US20090104132 |
Topical anti-inflammatory compositions comprising O/W emulsions containing pro-penetrating glycols
Topically applicable compositions in the form of oil-in-water emulsions contain a pro-penetrating system including at least one glycol and at least one additional pro-penetrating agent, a suitable...
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US20090098069 |
TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS
An alcohol-free, transdermal drug delivery composition administered via a metered spray drug delivery device is described herein. The non-occlusive transdermal drug delivery composition includes a...
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US20090092687 |
Prhormone composition and method of use thereof
The invention provides methods and compositions for maintaining a state of sexual wellness in a healthy human by providing a dietary supplement comprising one or more sexual steroid prohormones.
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US20090082321 |
STEROID CONTAINING DRUG DELIVERY SYSTEMS
Pharmaceutical composition for intraocular use comprising a glucocorticoid derivative, such as beclomethasone 17,21-diproprionate admixed with a biodegradable polymer such as a...
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US20090075961 |
Testosterone Oral Dosage Formulations And Associated Methods
Solid oral dosage forms of testosterone and methods for the preparation thereof are disclosed and described. The solid oral dosage form may include a therapeutically effective amount of...
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US20090075958 |
CLOBETASOL PROPIONATE SHAMPOOS FOR THE TREATMENT OF SEBORRHEIC DERMATITIS OF THE SCALP
Seborrheic dermatitis is effectively/safely treated by topically applying a corticosteroid shampoo, notably a clobetasol propionate shampoo, onto the scalp of a human subject afflicted therewith.
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US20090074873 |
Nanoparticulate beclomethasone dipropionate compositions
There is disclosed an aerosol comprising droplets of an aqueous dispersion of nanoparticles, said nanoparticles comprising insoluble therapeutic or diagnostic agent particles having a surface...
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US20090074828 |
POLY(AMINO ACID) TARGETING MOIETIES
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
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US20090074721 |
METHODS FOR TREATING VIRAL INFECTION WITH ORAL OR INJECTIBEL DRUG SOLUTION
Pharmaceutical composition comprising compounds and/or compositions useful to inhibit viral replication are disclosed.
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US20090069279 |
INVERT EMULSIONS CONTAINING DHEA
Stable, recrystallization-resistant invert emulsions, suited, e.g., for preventing/treating the signs of chronological or actinic skin aging and for preventing/treating atrophy of the skin or...
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US20090062248 |
OPTIMIZING MIFEPRISTONE LEVELS IN PLASMA SERUM OF PATIENTS SUFFERING FROM MENTAL DISORDERS TREATABLE WITH GLUCOCORTICOID RECEPTOR ANTAGONISTS
The present invention provides a method for optimizing levels of mifepristone in a patient suffering from a mental disorder amenable to treatment by mifepristone. The method comprises the steps of...
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US20090062245 |
Modulation of Neurodegenerative Diseases Through The Progesterone Receptor
Methods for modulating hormonal pathways involving the progesterone receptor in a subject with a neurodegenerative disorder, are provided. Progesterone receptor activity is modulated by...
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US20090062242 |
METHODS AND COMPOSITIONS FOR TREATING GASTROINTESTINAL CONDITIONS
Methods and compositions for treating a condition involving gastrointestinal symptoms comprising administering to a patient in need of such treatment an effective amount of a P-glycoprotein...
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US20090054386 |
Compositions and Methods for Inducing Bone Growth and Inhibiting Bone Loss
Compositions useful for inducing bone growth or inhibiting bone loss in an animal comprising one or more isoflavones or isoflavone metabolites and methods for inducing bone growth or inhibiting...
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US20090054385 |
SOLID INHALATION FORMULATIONS OF DEHYDROEPIANDROSTERONE DERIVATIVES
Solid pharmaceutical compositions and kits for administration to the lungs comprise a carrier and an agent for the treatment of bronchoconstriction and asthma, wherein the agent comprises a...
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