Matches 1 - 50 out of 323 1 2 3 4 5 6 7 >


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US20150018323 3B-HYDROXYSTEROID DEHYDROGENASE IN STEROID-DEPENDENT DISEASE  
Methods and kits for characterizing a subject having a steroid-dependent disease such as prostate cancer are described. A method of treating a steroid-dependent disease in a subject by obtaining a...
US20150216880 INDUCING LACTATION IN NURSING FEMALES  
A topical cream applied to a nipple of a lactating female induces lactation. The cream comprises a base cream having from about 0.5% to about 10%, by volume, of a steroid, based upon the total...
US20140045804 TREATMENT OF HYPOACTIVE SEXUAL DISORDER (HSDD)  
A topical cream to be applied to the clitoris and hood of the vaginal area to create an intense libido and drive for orgasm. The cream comprises a base cream having from about 9.5% to about 10%,...
US20140031326 METHODS FOR THE TREATMENT OF FIBROMYALGIA AND CHRONIC FATIGUE SYNDROME  
The invention relates to methods for the treatment of fibromyalgia and chronic fatigue syndrome by administration of a transdermally applied androgen composition. The treatment is both safe and...
US20140287039 Abiraterone Acetate Formulation  
Pharmaceutical compositions, including unit dosage forms, comprising fine particle abiraterone acetate with or without an antioxidant and or a sequestering agent as well as methods for producing...
US20120237502 METHOD FOR TREATING BREAST CANCER AND OVARIAN CANCER  
The present invention relates to a method for the prevention or treatment of certain breast cancers or ovarian cancer comprising administering to a patient in need thereof of a therapeutically...
US20130022593 METHODS OF DIAGNOSING ENDOMETRIOSIS  
The present invention provides biomarkers for the diagnosis and prognosis of endometriosis. Generally, the methods of this invention find use in diagnosing or for providing a prognosis for...
US20100324004 Method for Treating Diabetes  
This application is directed to the use of steroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
US20140105933 METHODS FOR ASSESSING CANCER RECURRENCE  
Certain embodiments are directed to methods of identifying a subject having a higher risk of prostate cancer recurrence. The methods can include the step of measuring levels of one or more of...
US20130035304 SMALL MOLECULES FOR THE MODULATION OF MCL-1 AND METHODS OF MODULATING CELL DEATH, CELL DIVISION, CELL DIFFERENTIATION AND METHODS OF TREATING DISORDERS  
This invention relates to compounds which selectively bind to the survival protein MCL-1 with high affinity and selectivity, pharmaceutical compositions containing such compounds and the use of...
US20150037407 METHOD TO IMPROVE THE SAFETY OF HANDLING OF HIGH POTENCY DRUGS IN SOLID DOSAGE FORMS WITHOUT CHANGING THEIR EFFICACY  
A method to improve the safety of handling of drug substances that are dispensed as solid oral dosage forms is described that does not alter the drug-release profile and the therapeutic efficacy...
US20130251804 METHOD TO IMPROVE THE SAFETY OF HANDLING OF HIGH POTENCY DRUGS IN SOLID DOSAGE FORMS WITHOUT CHANGING THEIR EFFICACY  
A method to improve the safety of handling of drug substances that are dispensed as solid oral dosage forms is described that does not alter the drug-release profile and the therapeutic efficacy...
US20140228333 METHODS FOR INHIBITING MUSCLE ATROPHY  
In one aspect, the invention relates to methods for treating muscle atrophy by providing to an animal in need thereof an effective amount of a compound. The compound can modulate the expression...
US20150168413 DIAGNOSIS AND MONITORING TREATMENT OF PROSTRATE CANCER  
Provided herein are assays and methods related to determining a ratio of expression levels of PSA/PSMA or determining the expression level of PSMA in circulating tumor cells for diagnosis and/or...
US20130072464 PROGESTERONE RECEPTOR ANTAGONISTS  
The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of formula I with progesterone-antagonizing action and methods of production thereof, use thereof for...
US20130150336 Methods For Reducing Superoxide Anions in Eukaryotic Organisms  
Provided are methods and compositions for reducing superoxide anions such that a prophylactic or therapeutic effect against conditions associated with excess oxidative stress achieved. The...
US20130184245 ENDOMETRIOSIS TREATMENT  
A pharmaceutical composition comprises at least one nonlipoidal internal phase and at least one lipoidal external phase that is bioadhesive to a vaginal mucosal surface, and comprises danazol in...
US20110212935 COMPOSITIONS AND TREATMENT METHODS-4  
The invention relates to the use of compounds to ameliorate or treat an condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used...
US20140294737 TREATMENT OF RHINITIS  
The invention provides a method of treating rhinitis. The method comprises administering an effective amount of a danazol compound or a pharmaceutically acceptable salt thereof. The invention also...
US20130303500 COMPOUNDS AND METHODS FOR TREATING NEOPLASIA  
The invention features compounds, pharmaceutical compositions and methods useful for the treatment of neoplasia. In particular embodiments, the compounds of the invention are useful for the...
US20120238488 COMPOUNDS AND METHODS FOR TREATING NEOPLASIA  
The invention features compounds, pharmaceutical compositions and methods useful for the treatment of neoplasia. In particular embodiments, the compounds of the invention are useful for the...
US20150174263 COMPOSITIONS FOR TREATING CANCER AND METHODS FOR MAKING THE SAME  
Described herein are compositions and methods relating to chemotherapeutic agent conjugates and the treatment of cancer.
US20120071453 STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM  
A compound with general formula I for treatment of various diseases of the central nervous system, in treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter...
US20140309181 TREATMENT OF DISEASES RELATED TO ALPHA SUBUNITS OF SODIUM CHANNELS, VOLTAGE-GATED (SCNxA) WITH SMALL MOLECULES  
Small compounds that modulate the expression of and/or function of sodium channel, voltage-gated, alpha subunit (SCNxA) are presented. Pharmaceutical compositions containing such small molecules...
US20120276196 Pharmaceutical Compositions of a Neuroactive Steroid and Methods of Use Thereof  
The present invention relates to pharmaceutical compositions of the neuroactive steroid 3α-hydroxy-3β-methoxymethyl-21-(1′-imidazolyl)-5α-pregnan-20 -one or a pharmaceutically-acceptable salt or...
US20110123619 BUCCAL DELIVERY SYSTEM  
A buccal delivery system capable of being blended in a normal dry powder process and compressed using a standard tabletting machine, said buccal delivery system comprising a matrix of: (a) an...
US20110152212 Aqueous Formulations  
A method of preparing an aqueous formulation of an active material and such a formulation per se are described, wherein the active material has a very low solubility in water. The method may...
US20140213563 METHODS OF DIAGNOSING AND TREATING NEONATAL REVERSION TO FETAL CONSCIOUSNESS  
This invention provides methods of diagnosing and treating syndromes of reversion to fetal consciousness in a neonate.
US20150203528 TREATMENT OF PROSTATE CANCER  
Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat androgen...
US20140343024 TREATMENT OF PROSTATE CANCER  
Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat androgen...
US20110034428 Treatment of Prostate Cancer  
Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using such compounds to treat androgen...
US20110171307 METHODS AND PRODUCTS FOR TREATMENT OF DISEASES  
The present invention relates to the treatment of diseases and conditions with an effective amount of a steroid having those formulas given in the specification, or a pharmacologically-acceptable...
US20110171306 METHODS AND PRODUCTS FOR TREATMENT OF DISEASES  
The present invention relates to the treatment of diseases and conditions with an effective amount of a steroid having those formulas given in the specification, or a pharmacologically-acceptable...
US20140256694 STEROID ANTIBIOTIC CONJUGATES  
The present invention describes steroid antibiotic conjugates. These single drug entities are formed connecting a steroid moiety and two same antibiotics moieties, or a steroid moiety and two...
US20140155362 BHQ-CONJUGATES, AND RELATED COMPOUNDS, METHODS OF MAKING THE SAME, AND METHODS OF USE THEREOF  
Embodiments of the present disclosure provide for BHQ-conjugates and protected BHQ-conjugate precursor compounds, methods of making BHQ-conjugates and protected BHQ-conjugate precursor compounds,...
US20150132295 METHODS AND COMPOSITIONS FOR DIAGNOSING, PROGNOSING, AND TREATING ENDOMETRIOSIS  
This document provides methods and materials related to genetic variations associated with endometriosis. For example, this document provides methods for using such genetic variations to assess...
US20120282331 MAMMALIAN METABOLITES OF STEROIDS  
Described herein, in certain embodiments, are steroidal derivatives, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using...
US20150239928 CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS  
Disclosed herein are cationic steroidal antimicrobials (“CSAs” or “ceragenins”) and methods of making the same. Particularly advantageous methods are identified for the synthesis of CSAs. CSAs may...
US20140018337 Steroids Having 7-Oxygen and 17-Heteroaryl Substitution-3  
The invention relates to the use of compounds to ameliorate or treat an condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used...
US20140018336 Steroids Having 7-Oxygen and 17-Heteroaryl Substitution-2  
The invention relates to the use of compounds to ameliorate or treat an condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used...
US20120309722 THERAPEUTIC REGIMENS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS  
The invention features pharmaceutical compositions and dosing regimens for the treatment of immunoinflammatory disorders.
US20100284913 Methods and compositions for studying, imaging, and treating pain  
Saxitoxin analogue compounds, compositions, pharmaceutical compositions, methods of synthesis of saxitoxin analogues, methods of imaging, methods of treatment, including methods of treating pain,...
US20110144016 Methods and Compositions for Treating Cancer  
Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17α-hydroxylase/C17,20-lyase inhibitor, such as...
US20140088057 METHODS OF TREATING PRE-TERM LABOR  
A method of treating pre-term labor in pregnant human patient expressing melatonin receptors in her myometrial cells comprises administering an inhibitor of MT2R, an inhibitor of protein kinase C,...
US20110046599 Multi-Day Delivery Of Biologically Active Substances  
Compositions and methods for modifying biologically active substances to achieve multi-day delivery of such substances, particularly through oral or parenteral administration, are disclosed. The...
US20150099727 Aminosteroids for the Treatment of a PTP1B Associated Disease  
This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
US20120271275 MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING  
Improved medical devices and methods are provided comprising an anabolic agent for wound healing. These improved medical devices and methods can enhance wound healing in wounds from cuts,...
US20080085873 Disease treatment methods  
The invention relates to the use of compounds to ameliorate or treat a condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used...
US20120309730 OXYSTEROLS THAT ACTIVATE LIVER X RECEPTOR SIGNALING AND INHIBIT HEDGEHOG SIGNALING  
This invention relates, e.g., to compositions comprising oxysterol compounds represented by Formula I or Formula II, e.g., comprising one or more of Oxy 16, Oxy 22, Oxy30, Oxy 31, Oxy35, Oxy37,...
US20100196427 DELAYED-RELEASE GLUCOCORTICOID TREATMENT OF RHEUMATOID ARTHRITIS BY IMPROVING SIGNS AND SYMPTOMS, SHOWING MAJOR OR COMPLETE CLINICAL RESPONSE AND BY PREVENTING FROM JOINT DAMAGE  
The present invention refers to the treatment of a patient suffering from rheumatoid arthritis by showing a reduction in signs and symptoms, a major or complete clinical response (remission) or...

Matches 1 - 50 out of 323 1 2 3 4 5 6 7 >