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US20090258040 |
STEROID TREATMENT FOR HOT FLASHES
Embodiments of the invention relate to methods for treating individuals suffering from hot flashes by vomeronasally administering a therapeutically effective dosage of a steroid agent. The hot...
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US20090239834 |
MCC-257 MODULATION OF NEUROGENESIS
The disclosure provides methods and a composition for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis by use of...
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US20090226545 |
Anti-Glycation Methods and Compositions
The present invention comprises compositions that provide anti-glycation activity comprising a mineral extract composition or a mogroside/mineral extract composition or a mogroside composition....
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US20090221542 |
Inhibition of Inflammatory Cytokine Production With Tanshinones
Provided are methods of attenuating release of a proinflammatory cytokine from a mammalian cell. Also provided are methods of inhibiting or treating an inflammatory cytokine cascade in a mammal....
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US20090220571 |
SELF-EXPANDING DEVICES AND METHODS THEREFOR
Described here are delivery devices for delivering one or more implants to the body, and methods of using. The delivery devices may deliver implants to a variety of locations within the body, for a...
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US20090209504 |
Use of Digitalis-Like Compounds in the Treatment of Affective Disorders
Use of digitalis-like compounds such as 19-norbufalin derivatives in the treatment of affective disorders such as anxiety, depression and bipolar disorders is disclosed.
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US20090202660 |
Agents and Methods for Osteogenic Oxysterols Inhibition of Oxidative Stress on Osteogenic Cellular Differentiation
The present invention discloses oxygenic oxygenic oxysterols. Also disclosed, agents and methods for protecting, blocking or rescuing marrow stromal cells from the inhibitory effects of oxidative...
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US20090149429 |
ANTIVIRAL COMPOUNDS
The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
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US20090143347 |
Use of 3-methoxy-pregnenolone for the preparation of a drug for treating depressive disorders and long-term neurological diseases
The invention relates to the therapeutic use of pregnenolone derivatives for treating depressive disorders and long-term neurological diseases.
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US20090143346 |
Method for synthesizing furanosteroids
The present invention is a method for synthesizing furanosteroids. The method involves intramolecular Diels-Alder/retro-Diels-Alder reaction and tautomerization of a functionalized alkyne oxazole...
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US20090124585 |
Novel Crystalline Pharmaceutical Product
There are provided crystalline particles of unsolvated Form 1 polymorph of the compound of formula (I):
characterised in that the particles are in the form of substantially triangular plates.
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US20090111786 |
Compounds that Prevent Macrophage Apoptosis and Uses Thereof
The present invention relates to microbial infection, and in particular, the reduction of apoptosis associated with microbial infection, the screening of Liver X Receptor agonist and/or Retinoid X...
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US20090088412 |
COMPOSITION FOR TREATING CANCER CELLS AND PREPARATION METHOD THEREOF
A composition for treating cancer cells and a preparation method therefore is provided. The composition includes novel withanolide compounds derived from a Solanaceae plant, which the novel...
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US20090082318 |
DEUTERIUM-ENRICHED MOMETASONE
The present application describes deuterium-enriched mometasone, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
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US20090074721 |
METHODS FOR TREATING VIRAL INFECTION WITH ORAL OR INJECTIBEL DRUG SOLUTION
Pharmaceutical composition comprising compounds and/or compositions useful to inhibit viral replication are disclosed.
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US20090022671 |
TREATMENT METHODS
Disclosed are methods of treating rhinosinusitis of the upper airway passages in patients afflicted with said disease, which comprises administering at least once-a-day to the surfaces of said...
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US20080317862 |
Organic Compounds Comprising a Glycopyrrolium Salt
Medicaments comprising (A) an antimuscarinic agent and (B) a corticosteroid for the treatment of inflammatory or obstructive airways diseases.
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US20080300228 |
Crystalline Rostafuroxin
New crystalline forms of 17β-(3-Furyl)-5-βandrostane-3β,14β,17α-triol are described together with pharmaceutical composition containing the same and methods for their preparation. In...
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US20080299176 |
DRUG DELIVERY DEVICE COMPRISING CROSSLINKED POLYURETHANE-SILOXANE-CONTAINING COPOLYMERS
A drug delivery device for placement in the eye includes a drug core comprising a hydrophobic pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material...
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US20080293682 |
Novel Betulinic Acid Derivatives
The invention relates to novel betulinic acid derivatives of formula (I), wherein R is C(═CH 2 ) CH 3 or CH(CH 3 ) 2 ; R 2 together with the adjacent carbonyl group forms a carboxylic acid,...
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US20080279948 |
Treatment of Asthma and Copd Using Triple-Combination Therapy
A medicament comprising, separately or together (A) a compound of formula I
in free or salt or solvate form, wherein W, R x , R y , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 have the meanings...
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US20080261928 |
Method of Treating Human Preeclampsia Employing Resibufagenin
A method of treating preeclampsia including administering a therapeutically effective dose of resibufagenin to a patient having preeclampsia. Effecting the determination of the presence of...
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US20080249075 |
C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds
Retrosteroidal compounds corresponding to formula I, representing progesterone receptor modulators, and their production, and pharmaceutical preparations containing these compounds. These compounds...
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US20080234241 |
MELANOGENESIS INHIBITORS AND WHITENING AGENTS COMPRISING ERGOSTEROL DERIVATIVE AND COMPOSITIONS CONTAINING ERGOSTEROL DERIVATIVE
It is intended to provide a substance which is efficacious in whitening sun-burnt skin after UV irradiation and preventing, ameliorating and treating skin pigmentation (for example, spots and...
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US20080207576 |
Substituted sapogenins and their use
The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed
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US20080207574 |
WITHANOLIDES, PROBES AND BINDING TARGETS AND METHODS OF USE THEREOF
Novel withanolide chemical genetic probes identify the in vivo binding target of withaferin A, which is the intermediate filament type III protein vimentin. In addition, a withanolide-based small...
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US20080194530 |
Chemical Compounds
The invention provides sarsasapogenin in novel amorphous, crystalline, solvated and hydrated forms, and the use thereof in manufacturing pharmaceutical or edible grade sarsasapogenin and its...
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US20080182829 |
8Beta-Hydrocarbyl-Substituted Estratrienes As Selectively Active Estrogens
This invention describes the new 8β-substituted estratrienes of general formula I in which R 2 , R 3 , R 6 , R 6′ , R 7 , R 7′ , R 9 , R 11 , R 11′ , R 12 , R 14 , R 15 , R 15′ , R 16 , R...
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US20080119416 |
NEW STEROIDS HAVING INCREASED WATER SOLUBILITY AND RESISTANCE AGAINST METABOLISM, AND METHODS FOR THEIR PRODUCTION
Steroid compounds having increased resistance against metabolism and increased water solubility are disclosed, together with methods for their production. These substances are suitable for the...
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US20080118566 |
PREPARATION OF POWDER AGGLOMERATES
The invention relates to a method of producing an agglomerate of drug and solid binder. The process involves producing individual agglomerate particles and then converting the convertible amorphous...
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US20080113925 |
Compositions and Methods for Increasing Telomerase Activity
The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations....
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US20080107609 |
PULMONARY DISEASE TREATMENT
The invention relates to treating chronic obstructive pulmonary disease, involving the administration by inhalation of mometasone furoate particles in daily doses where at least about 250 μg of...
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US20080090791 |
Cystic fibrosis treatment methods
The invention relates to the use of compounds to ameliorate or treat an condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used...
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US20080070880 |
SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI-INFLAMMATORY ACTIVITY
A compound of formula (I):
wherein X represents O or S;
R 1 represents C 1-6 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkylmethyl or C 3-8 cycloalkenyl any of which optionally may be...
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US20080063601 |
Compositions and methods relating to polycystic kidney disease
Described herein are therapeutic strategies (methods and compositions) useful for treating conditions in which cilia are affected and which manifest with cysts and/or fibrosis, such as conditions...
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US20080032960 |
PI3 kinase antagonists
The present invention provides novel PI3-Kinase antagonists and methods of use thereof.
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US20080027371 |
Method and device for minimally invasive site specific ocular drug delivery
The present invention includes techniques for delivering an active agent into the eye of a subject. Accordingly, in one aspect a method may include delivering invasively an active agent into a...
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US20080021004 |
Sapogenin derivatives and their use in the treatment of cognitive dysfunction
The invention discloses the use of sapogenin derivatives in the treatment of cognitive dysfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed.
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US20080020024 |
Fast dissolving orally consumable films
A consumable film adapted to adhere to and dissolve in the oral cavity of a warm-blooded animal including humans, comprising at least one water soluble polymer, a taste masking effective amount of...
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