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US20090286748 |
ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF
The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides...
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US20090286747 |
MNTF PEPTIDE COMPOSITIONS AND METHODS OF USE
The present invention relates to novel Motoneuronotrophic Factors (MNTF) peptides and analogs thereof, including compositions capable of promoting the growth and viability of neurons. MNTF peptides...
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US20090286745 |
INHIBITION OF ALPHA-SYNUCLEIN AGGREGATION
This invention relates to the inhibition of alpha-synuclein aggregation using peptidyl compounds which are retroenantiomers of the alpha-synuclein sequence, in particular retroenantiomers of...
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US20090285754 |
PEPTIDES FOR TARGETING APOPTOTIC CELLS AND USES THEREOF
The present invention relates to a peptide capable of specifically targeting apoptotic cells undergoing apoptosis and a use thereof. More particularly, it relates to a peptide having an amino acid...
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US20090281042 |
COMPOSITIONS AND METHODS USING SAME FOR THE DETECTION OF VIRUSES
An isolated peptide is provided. The isolated peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17,...
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US20090281033 |
Control of radiation injury
The invention relates to the field of drug development against acute radiation injury caused by exposure to high-energy electromagnetic waves (X-rays, gamma rays) or particles (alpha particles,...
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US20090275503 |
DIASTEREOMERIC PEPTIDES FOR MODULATING T CELL IMMUNITY
The present invention provides diastereomeric peptides derived from the T Cell Receptor alpha Transmembrane Domain, and lipophilic conjugates thereof, which peptides and conjugates are effective in...
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US20090275500 |
PEPTIDE-CONTAINING FOOD INTAKE REGULATOR
A safe and widely-applicable food intake regulator can be provided by using at least one peptide selected from the group consisting of a fish or mammalian melanin-concentrating hormone (MCH) and...
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US20090274752 |
COSMETIC AND DERMATOLOGICAL FORMULATIONS OF MNTF PEPTIDES
The disclosure is directed to methods and compositions that include MNTF peptides and their analogs for cosmetic and dermatological purposes.
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US20090270309 |
USE OF LACTOFERRIN FRAGMENTS AND HYDROLYSATES
The present invention relates to use of at least one lactoferrin fragment or a lactoferrin hydrolysate or a mixture thereof for stimulating skeletal growth, inhibiting bone resorption, stimulating...
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US20090264372 |
UTILIZATION OF PEPTIDES AS ACTIVE INGREDIENTS FOR SLIMMING
A method of using proteins of the SIRT family or of polypeptide or peptide fragments of SIRT proteins as an active ingredient for slimming, alone or in combination with at least one other active...
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US20090264369 |
METHODS FOR REDUCING CD36 EXPRESSION
The invention provides a method for reducing CD36 expression in a cell. The method comprises contacting the cell with an effective amount of an aromatic-cationic peptide having at least one net...
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US20090263374 |
METHOD OF PREVENTING AND TREATING BRAIN INFARCTION
The present invention is intended to clarify the relationship between PAR-2 and cerebral infarction and thereby provide an efficient method of preventing and treating cerebral infarction, as well...
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US20090258834 |
Plasma protein-binding ligands
The invention provides an isolated or purified peptide that binds at least one plasma protein. In one embodiment, the isolated or purified peptide binds to fibrinogen, comprises no more than 10...
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US20090253639 |
OPIORPHIN PEPTIDE DERIVATIVES AS POTENT INHIBITORS OF ENKEPHALIN-DEGRADING ECTOPEPTIDASES
The present invention relates to modified opiorphin peptides as new inhibitors of metallo-ectopeptidases.
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US20090253636 |
Novel Antifungal Agent
It is intended to provide a novel peptide which can exert higher antifungal effect also on a patient whose organ function is impaired with no side effect problems. The peptide comprises the...
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US20090253633 |
Novel Combinations of DNAK Inhibitors With Known Antibacterial Agents
Compositions, methods and kits are provided comprising (a) a therapeutically effective amount of a DnaK inhibitor; and (b) a therapeutically effective amount of a known antibacterial agent. Such...
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US20090253631 |
Anti-Inflammatory Peptides
The present invention relates, inter alia, to a method of ameliorating an inflammatory skin condition. Thus, the present invention provides a peptide that includes the amino acid sequence KMIKP...
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US20090247464 |
Compositions and Methods for Topical Application and Transdermal Delivery of an Oligopeptide
The invention relates to the transdermal application of oligopeptides for reducing synaptic transmission in tissues of an animal. In one aspect, this invention relates to compositions comprising an...
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US20090246251 |
COATING COMPOSITIONS HAVING IMPROVED PERFORMANCE
The presently disclosed subject matter provides compositions comprising a first substrate-binding domain (a peptide or a polymer) having binding affinity for a tissue or a medical device, a second...
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US20090246250 |
COATING COMPOSITIONS HAVING IMPROVED PERFORMANCE
The presently disclosed subject matter provides compositions comprising a first substrate-binding domain (a peptide or a polymer) having binding affinity for a tissue or a medical device, a second...
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US20090246217 |
Novel Peptides for Treating and Preventing Immune-Related Disorders, Including Treating and Preventing Infection by Modulating Innate Immunity
In one aspect, the present invention provides isolated novel peptides that can be used to modulate innate immunity in a subject, and/or for the treatment of an immune-related disorder, including...
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US20090233871 |
Complexed polypeptide and adjuvant for improved vaccines
Immunogenic polypeptides having the capability to precipitate and focus a CpG adjuvant exhibit enhanced in vivo priming of a cytotoxic T-lymphocyte (CTL) response. Accordingly, compositions that...
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US20090233866 |
Screening Methods And The Use Of Agents Identified Using The Same
A method for isolating candidate peptides for the treatment of a disease or disorder with a causative agent with SOD activity, the method comprising the steps of: (i) contacting a plurality of...
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US20090233859 |
Competitive Regulation of Hepcidin mRNA by Soluble and Cell-Associated Hemojuvelin
Disclosed herein are hemojuvelin-specific siRNAs that vary hemojuvelin mRNA concentration. Also disclosed herein, GPI-hemojuvelin positively regulated hepcidin mRNA expression, independently of the...
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US20090232866 |
Oligopeptides as coating material for medical products
The present invention relates to a pharmaceutical composition comprising a caspase inhibitor and/or a compound of the general formula R-Lys-X, methods for coating medical products using said...
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US20090227520 |
Treatment methods using peptides related to amyloid precursor protein
The invention provides a compound having formula X 1 -Arg-Xaa-Arg-X 2 in which X 1 and X 2 are up to 30 amino acid residues and Xaa is an amino acid residue. A preferred compound is the...
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US20090227519 |
COMPOUNDS FOR CONTROL OF APPETITE
This invention relates generally to neuropeptide Y (“NPY”) Y 4 receptor agonists including pancreatic polypeptide (PP), analogs thereof, and peptide fragments of PP, e.g. PP(32-36), and...
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US20090227518 |
COMPOSITIONS AND METHODS FOR TREATING ACTIN-MEDIATED MEDICAL CONDITIONS
The present invention provides a method for treating a subject an actin-mediated medical condition by administering to the subject an actin modulator. In some embodiments, the actin-mediated...
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US20090227505 |
Methods and uses for protein breakdown products
Where it was generally thought that the smallest breakdown products of proteins had no specific biological function on their own, it now emerges that the body may utilize the normal process of...
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US20090226387 |
SYNTHETIC PEPTIDES FOR USE AS INHIBITORS OF NEUROTRANSMITTER SECRETION AND AS INDUCERS OF CELLULAR RELAXATION
The present invention describes materials and methods related to synthetic peptides which block the secretion of neurotransmitters and induce muscle relaxation, and use of said peptides as...
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US20090226369 |
STQ Peptides
The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured laminin with substantially greater...
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US20090221512 |
PHARMACEUTICAL COMPOSITION CONTAINING GHRP-6 TO PREVENT AND ELIMINATE FIBROSIS AND OTHER PATHOLOGICAL DEPOSITS IN TISSUES
The present invention is related to the use of secretagogue peptides repeatedly administered as part of a pharmaceutical composition that prevent and eradicate the deposition of pathological...
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US20090221506 |
GDNF DERIVED PEPTIDES
The present invention relates to peptide fragments derived from the proteins belonging to the TGFbeta superfamily, pharmaceutical compositions comprising said peptide fragments and uses thereof for...
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US20090221505 |
COMPOSITIONS AND METHODS RELATED TO SYNCHRONOUS SELECTION OF HOMING PEPTIDES FOR MULTIPLE TISSUES BY IN VIVO PHAGE DISPLAY
Embodiments of the invention include methods for selecting in parallel (i.e., synchronously or simultaneously) peptides that target a number of organs, in which each peptide targets distinct...
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US20090221482 |
TISSUE PROTECTIVE PEPTIDES AND USES THEREOF
The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present...
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US20090221476 |
Peptide Capable of Altering Tubulin Polymerization and use Thereof for Inhibiting Cell Proliferation
The invention concerns a peptide derived from intermediate filaments and an intermediate filament fragment capable of altering tubulin polymerization and used for inhibiting cell proliferation, and...
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US20090220581 |
METHODS OF REDUCING INFLAMMATION AND MUCUS HYPERSECRETION
Methods and compounds for decreasing MARCKS-related inflammation and MARCKS-related mucus hypersecretion or decreasing MARCKS-related inflammation in a subject by the administration of a N-terminal...
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US20090215702 |
Uv-Induced Dermatitis Inhibitor and Atopic Dermatitis Inhibitor
At least one substance selected from the group consisting of a water-soluble peptide comprising at least one unit selected from the group consisting of an isoleucylglycylseryl unit, a...
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US20090214580 |
Peptide mixtures with immunomodulatory activity
The present invention is related to complex peptide mixtures with immunomodulatory effects and methods for their use. The invention is further directed toward treatments of diseases through the...
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US20090214507 |
METHOD OF TREATING PREVENTING, INHIBITING OR REDUCING DAMAGE TO CARDIAC TISSUE
A method of treatment for treating, preventing, inhibiting or reducing damage to coronary tissue includes inducing at least one of a physiological function selected from: up-regulation of or...
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US20090214467 |
METHODS OF PROTECTING AGAINST APOPTOSIS USING LIPOPEPTIDES
The use of lipopeptides as inducers of NF-κB for the protection of mammals from the effects of apoptosis is described.
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US20090214427 |
Novel peptides
Isolated peptides comprising an amino acid sequence having Formula I
X 1 X 2 X 3 X 4 , I
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US20090209466 |
PEPTIDES WITH ANTI-PROLIFERATIVE ACTIVITY
The present invention relates to peptides with anti-proliferative activity, of sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3.
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US20090208484 |
R-SPONDIN COMPOSITIONS AND METHODS OF USE THEREOF
The invention provides for a method for screening compounds that bind to and modulate a regulator of Wnt signaling, R-spondin 4. The invention further provides for methods for diagnosing a...
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US20090203627 |
Specific binding sites in collagen for integrins and use thereof
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the...
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US20090203626 |
Pediatric Amino Acid Solution for Parenteral Nutrition
The present invention relates to an amino acid solution for the parenteral nutrition of pediatric patients. The amino acid solution provides for an increased concentration of glutamine, tyrosine,...
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US20090203621 |
Tripeptides that Down Regulate the Activity of Plasma Membrane transporters Including Sodium-D-Glucose Cotransporter Sglt1
The present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of a pharmaceutical...
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US20090203620 |
METHODS FOR ATTENUATING RELEASE OF INFLAMMATORY MEDIATORS AND PEPTIDES USEFUL THEREIN
The present invention includes methods of inhibiting or suppressing cellular secretory processes. More specifically the present invention relates to inhibiting or reducing the release of...
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US20090203619 |
Artificial platelets
Therapeutic agents suitable for use as artificial platelets are described. The agents comprise a fibrinogen binding precursor bound to an insoluble carrier, wherein the fibrinogen binding precursor...
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