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US20090280171 |
METHOD OF TREATMENT WITH PREDICTABLY BREAKABLE PHARMACEUTICAL TABLETS
The invention involves the use of finished dosage forms, e.g., tablets, by breaking or otherwise dividing them to produce a predictably accurate smaller or lower dose.
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US20090280115 |
Dihydropteridinones in the Treatment of Respiratory Diseases
The present invention relates to the use of dihydropteridinones of formula 1
wherein the groups X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 have the meanings given in the claims and...
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US20090270310 |
Process for the preparation of a nutrient formulation
The present invention relates to a process for increasing the efficacy and/or bioavailability of a nutrient formulation or composition for the treatment and/or prevention of inflammatory processes...
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US20090263408 |
FORMULATION AND PRESENTATION OF MEDICAMENTS
A medicament package ( 10,30 ) comprises a vessel ( 12,32 ) adapted to hold a quantity of a liquid vehicle. The vessel ( 12,32 ) has an opening formed therein, to which opening is bonded a...
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US20090252801 |
Process for the Preparation of Micronised Sterile Steroids
The present invention relates to a process for the preparation of micronised sterile steroids, comprising sterilisation of the steroids in crystalline form by means of irradiation with gamma or...
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US20090247492 |
MANGANESE BASED ORGANOMETALLIC COMPLEXES, PHARMACEUTICAL COMPOSITIONS AND DIETETIC PRODUCTS
The invention relates to compounds and their uses, particularly in the pharmaceutical and dietetic industries. The invention discloses complexes having Mn-SOD like activities, as well as methods...
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US20090238858 |
Compositions and Methods for Treating Ophthalmic Diseases
Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with...
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US20090238758 |
RANDOM AND NON-RANDOM ALKYLENE OXIDE POLYMER ALLOY COMPOSITIONS
A polymeric material comprised of (i) at least one random copolymer comprised of ethylene oxide and one or more other alkylene oxide(s) and (ii) at least one non-random polymer comprised of one or...
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US20090203662 |
NOVEL DERIVATIVES OF CHOLEST-4-EN-3-ONE OXIME, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PREPARATION METHOD
The object of the invention is the use as a drug of a compound fitting formula I
wherein X represents an oxygen atom or a ═N—OH group
and R represents a group selected from
or one...
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US20090197841 |
Inhalant Propellant-Free Aerosol Formulation
The invention relates to inhalant propellant-free aerosol formulations containing at least one inert, non-volatile auxiliary substance for adjusting defined droplet sizes.
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US20090197796 |
Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors
Methods are provided for treating HPG axis-positive cancers, preventing or slowing proliferation of cells of HPG axis-positive cancer origin, preventing HPG axis-positive cancers in a patient at...
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US20090186861 |
Process for Production of Fatty Acids, Fatty Acid Esters and Sterolesters from Soapstock
The invention relates to a process for production of fatty acids directly from soapstock generated in the alkali refining process including the steps of (a) adding a lipase directly to the alkaline...
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US20090175925 |
PASSIVE TIME RELEASED SOLUTE TREATMENT
Devices and methods for delivery of a solute to increase blood sugar levels between certain hours in a form that allows for gradual delivery. One variation includes devices and methods for the...
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US20090169625 |
Electrostatically Controlled Hydrogels
The compositions and methods disclosed herein pertain to the manufacture and use of hydrogels. The disclosed compositions and methods pertain to hydrogels capable of induction by a variety of...
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US20090169498 |
Controlled Release Gels
The invention relates to the field of gel-based delivery systems for a compound of interest, like a drug or cosmetic agent. Provided is a gel comprising at least one nonpolymeric gelator and at...
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US20090142323 |
METHODS FOR TREATING A DISORDER BY REGULATING GPRC6A
A disorder related to a non-genomic androgen response or a metabolic syndrome can be treated, inhibited, and/or prevented by regulating an expression level and/or activity of GPRC6A. Such a method...
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US20090118215 |
Bioresorbable Controlled-Release Composition
A novel method for the preparation of a highly densified and at least partly, preferably fully or almost fully hydrated ceramic for use in the preparation of a pharmaceutical composition notably...
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US20090105205 |
METHODS OF TREATING DISEASE STATES USING ANTIANGIOGENIC AGENTS
Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae:
wherein R a ...
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US20090105199 |
OLIGOMERS OF CHOLESTEROL, CHOLESTEROL SULPHATE AND CHOLESTEROL ESTERS AND ALSO DRUGS CONTAINING THESE
The invention relates to new substances which are derived from cholesterol, cholesterol sulphate and cholesterol esters of a natural, semi-synthetic or synthetic origin in that they represent...
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US20090092727 |
WATER-DISPERSIBLE PHYTOSTEROL-SURFACTANT CONGLOMERATE PARTICLES
A hot and cold water-dispersible dry-milled composition including phytosterol-surfactant conglomerate (PSC) particles which include a blend of dry microparticulate non-ester phytosterols and a dry...
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US20090082322 |
Gender Differences in Experimental Aortic Aneurysm Formation
The present invention generally relates to the relevance of gender differences on abdominal aortic aneurysm (AAA) formation and to methods of inhibiting, preventing, and/or treating AAA formation...
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US20090075888 |
Cardiovascular and Brain Cell Therapy Using Intracellular Ryanodine Receptor Modulation by the Estrogen Receptor Beta
The present invention includes compositions and methods for screening for a candidate substance with ryanodine receptor (RyR)-modulatory activity, the method including: determining the...
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US20090068257 |
BETULONIC AND BETULINIC ACID DERIVATIVES
The present invention relates to betulonic and betulinic acid derivatives and, in particular, to C-28 and C-3 derivatives. The present invention relates to betulonic acid esters, dihydro-betulonic...
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US20090068185 |
Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy,...
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US20090062243 |
Lupane-Type Triterpenoids Modified at 30-Position and Analogues Thereof
The present invention comprises lupine-type triterpenoids that inhibit cell proliferations, in particular cancer and conditions associated with cancer. For example, associated malignancies include...
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US20090047321 |
ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS
Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing...
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US20090042846 |
Topical Delivery System for Phytosterols
This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne,...
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US20090024108 |
Methods and Devices for Delivery of Compositions to Conduits
The present invention comprises systems, methods and devices for the delivery of visualizable or treatment compositions or therapeutic agents comprising device elements for diagnosis and/or...
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US20090012494 |
INTRADERMAL DELIVERY OF BIOLOGICAL AGENTS
The present invention relates to methods for intradermally delivering one or more biologically active agents such as vaccines and therapeutic agents into the dermis layer of the skin of a subject...
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US20080317805 |
LOCALLY ADMINISTRATED LOW DOSES OF CORTICOSTEROIDS
This invention provides for using a locally delivered low dose of a corticosteroid to treat pain caused by any inflammatory disease including sciatica, herniated disc, stenosis, mylopathy, low back...
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US20080311217 |
TOPICIAL COMPOSITION FOR TREATING PAIN
Topical compositions having as the active ingredient a lipid, fatty acid ester, natural wax, sterol, or combinations thereof referred to herein as “lipophilic vehicle” or “LV” and methods...
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US20080299176 |
DRUG DELIVERY DEVICE COMPRISING CROSSLINKED POLYURETHANE-SILOXANE-CONTAINING COPOLYMERS
A drug delivery device for placement in the eye includes a drug core comprising a hydrophobic pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material...
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US20080299166 |
NOVEL BIOMATERIALS, THEIR PREPARATION AND USE
The present invention relates to novel materials, particularly biomaterials, in form of a precipitate, comprising at least an anionic polymeric component which is as such soluble in water and an...
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US20080293683 |
Hormone Replacement Therapy
A hormone replacement therapy formulation and method comprising selective estrogenic compounds which preferentially stimulate the estrogen receptor alpha over the estrogen receptor beta.
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US20080292733 |
Antioxidant and Fe2+ Chelating Properties of Herbal Extracts
The present invention is directed to antioxidative and antiproliferative agents containing North American ginseng (proprietary extract HT1001) alone or in combination with Ginkgo biloba (GB),...
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US20080287404 |
High Purity 17Alpha-Cyanomethyl-17Beta-Hydroxy-Estra-4,9-Diene-3- One and Process For the Syntheses Thereof
The invention relates to a new process for the synthesis of high purity 17α-cyanomethyl-17β-hydroxy-estra-4,9-diene-3-one (further on dienogest) of formula (I) from...
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US20080286362 |
Compositions Exhibiting Improved Flowability
Powder compositions exhibiting improved flow properties. The compositions generally contain a bulk solid material in the form of a powder and surface-modified nanoparticles. Methods of improving...
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US20080274195 |
Compositions and Methods for Making and Using Nanoemulsions
The present invention discloses an improved nanoemulsion comprising a uniform and discrete range of very small particle nano-sized diameters. This uniformity results in improved bioavailability of...
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US20080267909 |
PHAGOCYTE ENHANCEMENT THERAPY FOR ATHEROSCLEROSIS
Compounds that increase phagocytosis of apoptotic macrophages or necrotic cells that are associated with advanced atherosclerotic lesions are useful for treating atherosclerosis. Methods are...
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US20080262445 |
Transdermal Delivery of Hydrophobic Bioactive Agents
A method and related compositions, including the use of N-acyl derivatives of sarcosine, provide for the delivery of bioactive agents through tissue surfaces such as the skin. The method and...
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US20080261927 |
Stable Aqueous Suspension
An aqueous suspension of a hydrophobic nutrient is disclosed. In particular, the nutrient, in ester form, is combined with a selected dispersion aid and a dispersion agent(s), and then dispersed in...
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US20080255076 |
Steroid-Derived Pharmaceutical Compositions
The present invention relates to the use of specific steroid derivatives in the preparation of medicaments for the treatment or prevention and/or amelioration of disorders relating to pathological...
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US20080254085 |
Degradable Polymers Incorporating Gamma-Butyrolactone
Disclosed herein are implantable medical devices having controlled release biodegradable polymer coatings thereon wherein the polymer is formed from ring opening of γ-butyrolactone and at least...
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US20080249036 |
Antagonist Against Tolerance to Anticancer Drugs
An ABC transporter protein expression inhibitor comprising, as the active ingredient(s), 0.001 to 100 nM of one or more members selected from among steroid hormones, compounds having a female...
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US20080248123 |
Nanoparticulate anticonvulsant and immunosuppressive compositions
Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the...
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US20080234243 |
METHOD OF TREATING AMYLOIDOSIS MEDIATED DISEASES
The compounds of the present invention can be used to inhibit formation of beta-amyloid protein. The present invention provides methods of preventing, delaying onset of, or treating diseases or...
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US20080227760 |
Method of Extracting Ginsengnoside Rg2m, Pharmaceutical Composition Including Ginsengnoside Rg2, and Uses Thereof
The present invention provides a method of extracting ginsenoside Rg 2 , which is applied to mass production. The method of the present invention employs gradient salting-out instead of...
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US20080220046 |
Terpolymers for Controlled Release of Bioactive Agents From Implantable Medical Devices
Disclosed herein are implantable medical devices comprising controlled release terpolymers and at least one drug releasable from said terpolymers coating. The terpolymers of the present invention...
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US20080219951 |
Stabilization of Biologically Active Proteins With Mixtures of Polysaccharides and Amino Acid Based Compounds
The invention provides heat stable aqueous solutions or gels comprising a biologically active protein and a stabilizing effective amount of a mixture of a polysaccharide and an amino acid based...
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US20080207576 |
Substituted sapogenins and their use
The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed
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