Matches 1 - 20 out of 20


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US20140037547 NOVEL PEPTIDIC ACTIVATORS OF TYPE I cGMP DEPENDENT PROTEIN KINASES AND USES THEREOF  
The present invention relates to cGMP protein kinase (PKG) and regulatory domains and methods of use thereof. The structural determination of PKG domains is also described. cGMP independent PKG...
US20060025386 Method of treatment of retinal ischemia with diazoxide  
A composition including diazoxide (7-chloro-3-methyl-2H-1,2,4-benzothiadiazine-1,1-dioxide) for the treatment and/or prevention of retinal ischemia and of diseases associated with retinal...
US20060128673 Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions  
Described is a novel combination therapy for diabetes mellitus type I and/or for obesity and its concomitant and/or secondary diseases or conditions, in particular the metabolic syndrome and/or...
US20060247216 Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments  
The present invention relates to multifunctional steroid compounds combining a steroid component with SOD mimic component and optionally also with NO donor component, and to their use in treating...
US20050009789 Cyclooxygenase inhibition with nitroxyl  
Nitroxyl is used to inhibit COX-2 activity and particularly to selectively inhibit COX-2 activity. Nitroxyl also is used to treat conditions that respond favorably to inhibition of COX-2 activity...
US20050070509 Antimycotic agent  
The present invention relates to a metal salt for use in pharmacy, to pharmaceutical compositions comprising it, and to the use for preparing a pharmaceutical composition for treating diseases...
US20090281067 Nitroxyl progenitor compounds and methods of use  
Described herein are nitroxyl progenitor compounds, and compositions including, and methods or generating, the compounds thereof, and methods of treating or preventing disease and disease symptoms...
US20060166894 Ace-inhibitors having antioxidant and no-donor activity  
Multifonctional ACE inhibitor compounds are provided, that combine ACE-inhibiting activity with capability to scavenge superoxide and other reactive oxygen species, and that may further function...
US20050208088 Pesticidal composition and method for pest control  
A method of protecting a plant against shoot or foliar insects and/or representatives of the order Acarina, which comprises treating the plant propagation material thereof with (a) a nematicidally...
US20070059351 Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods  
The present invention is drawn to a transdermal patch for the delivery of a nitric oxide-donor and a second active agent. The patch can comprise a backing layer and an active agent-containing...
US20090203653 Compositions and Methods Using Apocynin Compounds and Nitric Oxide Donors  
The invention describes novel compositions comprising at least one apocynin compound or a pharmaceutically acceptable salt thereof, and at least one nitric oxide donor, and, optionally, at least...
US20060039950 Multi-functional biocompatible coatings for intravascular devices  
A polymeric coating is adapted to substantially eliminate thrombus formation when in contact with blood. The polymeric coating includes a first polymeric layer and a second polymeric layer....
US20090186859 DIAZENIUMDIOLATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, COMPOSITIONS THEREOF, AND RELATED METHODS  
Disclosed are compounds that release nitric oxide, e.g., a compound of Formula (I) wherein R1-10, X, and n are as described herein, which are NSAID derivatives comprising a diazeniumdiolate moiety...
US20090298795 Thiol-Sensitive Positive Inotropes  
The present invention relates to methods for treating diastolic dysfunction or a disease, disorder or condition associated with diastolic dysfunction, methods for treating heart failure, methods...
US20060135485 Microbicidal compositions and their use  
A composition comprising a potassium salt of N′-hydroxy-N-cyclohexyldiazenium oxide (KHDO) and a diluent is useful for killing fungi. Such a composition but which additionally includes at least...
US20070207179 Medical Device  
A medical device, such as a guide wire, an embolization device, or a guide shaft for a micro catheter, comprises a solid and/or non-expandable core member made from e.g. metal, such as tantalum,...
US20060293288 Use of resolvins to treat gastrointestinal diseases  
The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as...
US20100298277 ANGIOTENSIN II RECEPTOR ANTAGONISTS  
A compound having the structure wherein R is an angiotensin receptor blocking groupY is —(CR1R20)1-7R5, or —C(O)(CR1R20)1-7R5;R1 and R20 are independently selected from the group consisting of...
US20050153940 Method for using potassium channel activation for delivering a medicant to an abnormal brain region and/or a malignant tumor  
Disclosed are methods of selectively delivering a medicant to an abnormal brain region and/or to a malignant tumor in a mammalian subject, including a human. A medicant is administered...
US20070060551 Methods of using isothiazole derivatives to treat cancer or inflammation  
Methods of using substituted 3,5-dithio-, disulfinyl-or disulfonyl-isothiazole derivatives to treat cancer or inflammation in a mammal and pharmaceutical compositions containing such derivatives...

Matches 1 - 20 out of 20