Matches 1 - 50 out of 230 1 2 3 4 5 >


Match Document Document Title
US20150094266 XYLOGLUCAN AND PROTEIN COMPOSITIONS FOR THE TREATMENT OF INTESTINAL DISORDERS  
Compositions include synergistic combinations of xyloglucans and vegetable or animal proteins that are useful in the treatment of intestinal disorders or of disorders originating from the...
US20110305634 Methods and systems for adenovirus interaction with desmoglein 2 (DSG2)  
The present invention provides compositions and methods for treating disorders associated with epithelial tissues.
US20110251126 INTESTINAL TREATMENT  
Y4 receptor agonists which are selective for the Y4 receptor over the Y1 and Y2 receptors, are useful in the prevention and/or treatment of damage to bowel function caused by radiation therapy,...
US20110098223 USE OF THE PAT NANOPEPTIDE IN THE TREATMENT OF AUTOIMMUNE DISEASES  
The invention refers to the use of the PAT nonapeptide which is a thymuline analog in the treatment of autoimmune diseases, in particular of rheumatoid arthritis and intestinal bowel diseases...
US20140045756 METHODS AND COMPOSITIONS FOR MODULATING TNF/TNFR SIGNALING  
The present disclosure relates to methods and compositions for modulating TNF and TNFR signaling. In particular, the disclosure describes methods and compositions for inhibiting TNFα signaling,...
US20150037350 NEGATIVE MODULATOR OF HEDGEHOG SIGNALLING FOR USE IN TREATING TH2-MEDIATED DISEASES  
The invention provides means for treating Th1- and Th2-mediated diseases, such as asthma, allergic dermatitis and Th2-driven cancer. The invention extends to pharmaceutical compositions for use in...
US20140037634 REGULATORY T CELL MEDIATOR PROTEINS AND USES THEREOF  
The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates αCD3 proliferation of T cells in vitro. A...
US20130190239 Formulations Comprising Linaclotide  
The present invention relates to stable compositions comprising linaclotide, as well as to various methods and processes for the preparation and use of the compositions.
US20130108602 METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE  
Methods of decreasing, reducing, inhibiting, suppressing, limiting or controlling an undesirable or aberrant immune response, immune disorder, inflammatory response, or inflammation in a subject;...
US20060122106 Prevention and/or treatment of inflammatory bowel disease using pyy or agonists thereof  
A novel use of PYY or a PYY agonist is disclosed for treating a bowel condition such as inflammatory bowel disease (e.g. ulcerative colitis and Crohn's disease), bowel atrophy, loss of bowel...
US20130045239 Method for Modulating the Pharmacodynamic Effect of Orally Administered Guanylate Cyclase Receptor Agonists  
A method of modulating the pharmacodynamic effect of a GC-C receptor agonist polypeptide formulation in a subject in need of such treatment is disclosed, The method comprises administering the...
US20130236509 MICROPARTICLES COMPRISING A SMALL HEAT-SHOCK PROTEIN  
The invention relates to a biodegradable microparticle having a diameter between 0.2 and 3.5 micrometer and comprising a pharmaceutically effective amount of at least one small heat-shock protein...
US20130059773 COMPOUNDS FOR THE TREATMENT OF INFLAMMATION AND NEUTROPENIA  
The present invention concerns compounds modulating apoptosis of neutrophil cells. In particular, the invention concerns compounds inhibiting an interaction between Proliferating Cell Nuclear...
US20140030251 COMPOSITION AND METHOD FOR REDUCING TISSUE DAMAGE FROM INFLAMMATORY DISORDER OR PATHOGENIC INFECTION  
Compositions and methods for preventing or ameliorating tissue damage caused by an inflammatory disorder or pathogenic infections are described. In one aspect, a method for preventing or...
US20140187474 THERAPEUTIC USE OF MUCIN GLYCANS  
A therapeutic formulation containing mucin glycans derived from one or a number of nutritionally appropriate sources is described.
US20120071412 METHODS OF USING MACROCYCLIC AGONISTS OF THE GHRELIN RECEPTOR FOR TREATMENT OF GASTROINTESTINAL MOTILITY DISORDERS  
The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective agonists of the ghrelin receptor (growth hormone secretagogue...
US20110081323 Methods and compositions for organ and tissue functionality  
Materials and methods for treating tissue defects in human or animal tissues using implantable cells are described. Further, culture techniques and factors for enhancing these procedures, and cell...
US20120277145 Compounds  
The present invention pertains generally to certain compounds of the deoxyactagardine A and B type. Such compounds are suitable for use in the treatment of microbial infections, for example...
US20050164925 Treatment of gastroparesis  
The invention relates to the use of GLP-1 compounds to treat gastroparesis. Patients with gastroparesis generally experience a delay in gastric emptying. GLP-1 compounds can be used to regulate...
US20130072421 TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT)  
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a...
US20110319317 TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRT1  
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sirtuin 1 (SIRT1), in particular, by targeting natural antisense polynucleotides of...
US20110144021 THERAPEUTIC PROTEINS FROM LATEX  
The invention refers to compositions that comprise the protein preparation, obtained from the latex of Hevea brasiliensis, in a low concentration. Additionally, the invention refers to the use of...
US20130225479 Methods and Compositions for Treating Inflammation  
The present invention provides methods and compositions for treating inflammation and inflammatory disorders in a subject, by administering an effective amount of KSHV-Orf63 and/or active peptides...
US20070219128 Medical and health-care uses of pufferfish type I collagen extract and processes for producing said extract  
The present invention relates to the use of pufferfish type I collagen extract as effective ingredient in the manufacture of medicaments and health-care foods for prevention and treatment of the...
US20120301397 DIAGNOSIS OF MACROPHAGE MEDIATED DISEASE  
The invention relates to a method of treating or monitoring/diagnosing a disease state mediated by activated macrophages. The method comprises the step of administering to a patient suffering from...
US20150119328 Treatments for Gastrointestinal Disorders  
Described herein are peptides, compositions, and related methods for treating upper gastrointestinal disorders and conditions (e.g., dyspepsia, gastroparesis, post-operative gastric ileus, a...
US20140256634 Treatments for Gastrointestinal Disorders  
Described herein are peptides, compositions, and related methods for treating upper gastrointestinal disorders and conditions (e.g., dyspepsia, gastroparesis, post-operative gastric ileus, a...
US20070025991 Use of antagonists of ghrelin or ghrelin receptor to treat intestinal inflammation  
Methods for treating intestinal inflammation or ghrelin-mediated inflammation by inhibiting the activity of ghrelin or its receptor are described. Also described are methods for identifying...
US20110245159 Salts, Solvates and Pharmaceutical Compositions of Macrocyclic Ghrelin Receptor Agonists and Methods of Using the Same  
The present invention provides novel salts and solvates of macrocyclic compounds that bind to and/or are functional agonists of the ghrelin (growth hormone secretagogue) receptor. The invention...
US20120135916 MONOMERIC AND DIMERIC FORMS OF ADIPONECTIN RECEPTOR FRAGMENTS AND METHODS OF USE  
Methods are disclosed for determining progression of a condition, onset of a condition, or efficacy of treatment of a condition characterized by an adipocyte imbalance in a patient. In addition,...
US20140336119 POLYPEPTIDES TARGETING GLYCOSYLATED MUC2 PROTEINS, METHODS OF SYNTHESIS, THEIR NUCLEIC ACIDS AND USES THEREOF  
The invention relates to polypeptides, defined through a consensus sequence, having a length from 10 to 80 amino-acid residues, and whose polypeptidic sequence comprises or consists of the...
US20130296224 METHOD FOR TREATMENT OF INFLAMMATORY DISEASE AND DISORDER  
The present disclosure provides a method, composition and kit for treatment of inflammatory disease and disorder using PKC isoform modulators. Exemplary modulators include inhibitors of PKC-alpha,...
US20140179607 Treatments for Gastrointestinal Disorders  
The present invention provides peptides that are useful for the treatment of gastrointestinal disorders. The present invention also provides compositions and methods of treating gastrointestinal...
US20140024593 Treatments of Gastrointestinal Disorders  
The present invention provides peptides that are useful for the treatment of gastrointestinal disorders. The present invention also provides compositions and methods of treating gastrointestinal...
US20130085107 Treatments for Gastrointestinal Disorders  
The present invention provides peptides that are useful for the treatment of gastrointestinal disorders. The present invention also provides compositions and methods of treating gastrointestinal...
US20110118184 Treatments of Gastrointestinal Disorders  
The present invention provides peptides that are useful for the treatment of gastrointestinal disorders. The present invention also provides compositions and methods of treating gastrointestinal...
US20110319330 Methods For Treating Arthritis, Autoimmune Disease, and Ischemia-Reperfusion Injury  
The instant invention provides a method of treating an animal suffering a disease characterized by excessive apoptosis by administering a therapeutically effective amount of at least one serine...
US20060128622 Therapeutic formulations of keratinocyte growth factor  
The present invention provides long-term stable formulations of lyophilized keratinocyte growth factor and methods for making a lyophilized composition comprising keratinocyte growth factor.
US20140088015 Mucin 3 EGF-like Domains  
The invention provides for a mucin3 polypeptide, a polypeptide including a mucin3 EGF like domain, and nucleic acids encoding such polypeptides. The invention also provides for methods of treating...
US20120258905 VITAMIN RECEPTOR DRUG DELIVERY CONJUGATES FOR TREATING INFLAMMATION  
Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in...
US20120328632 INHIBITION OF LEUKOCYTE ADHESION  
This invention relates to the inhibition of intercellular adhesion mediated by L-selectin by administering a newly identified L-selectin ligand, CD34. More particularly, the invention concerns a...
US20070010446 METHODS FOR TREATING INFLAMMATION USING THYROID STIMULATING HORMONE  
Thyroid stimulating hormone has been shown to have anti-inflammatory activity. Polypeptides of thyroid stimulating hormone have a novel use as an anti-inflammatory agent as a stand-alone therapy,...
US20120021987 Mucin 3 EGF-Like Domains  
The invention provides for a mucin3 polypeptide, a polypeptide including a mucin3 EGFlike domain, and nucleic acids encoding such polypeptides. The invention also provides for methods of treating...
US20120141538 MODULATORS OF THE CX3CRI RECEPTOR AND THERAPEUTIC USES THEREOF  
The present invention concerns modulators of the CX3CR1 receptor. More specifically, antagonists and agonists of the CX3CR1 receptor have been identified. These antagonists and agonists can be...
US20140187470 Agonists of Guanylate Cyclase Useful For the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders  
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a...
US20150148290 Macrocyclic Modulators of the Ghrelin Receptor  
The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective modulators of the ghrelin receptor (growth hormone secretagogue...
US20140287001 Compositions Useful For The Treatment Of Gastrointestinal Disorders  
This invention provides novel peptides and methods to prevent, control, and treat an inflammation, cancer and other disorders, particularly of the gastrointestinal tract and the lung by...
US20070098685 Methods and kits to treat chronic inflammatory immune diseases by administering a proteasome inhibitor and an interleukin 2 receptor agonist  
Methods and kits for treatment of immune diseases with an IL2 receptor agonist and a proteasome inhibitor are provided.
US20070123460 Probiotic compounds from Lactobacillus GG and uses therefor  
The invention provides methods and compositions for the treatment of inflammatory disorders, such as inflammatory bowel diseases (IBDs). The use of bacteria-free, probiotic-derived compounds...
US20070098722 Medicament comprising inhibitors of long pentraxin ptx3  
The use of inhibitors of long pentraxin PTX3 for the preparation of a medicament for the prevention and treatment of autoimmune diseases and of degenerative diseases of bone and cartilage is...

Matches 1 - 50 out of 230 1 2 3 4 5 >