|
Match
|
Document |
Document Title |
|
|
US20070098685 |
Methods and kits to treat chronic inflammatory immune diseases by administering a proteasome inhibitor and an interleukin 2 receptor agonist
Methods and kits for treatment of immune diseases with an IL2 receptor agonist and a proteasome inhibitor are provided.
|
|
|
US20060252681 |
Pain relief agents
The present invention concerns the use of a heat shock polypeptide and/or an encoding nucleic acid sequence in the manufacture of a medicament for use in the relief of pain. In particular the...
|
|
|
US20070123460 |
Probiotic compounds from Lactobacillus GG and uses therefor
The invention provides methods and compositions for the treatment of inflammatory disorders, such as inflammatory bowel diseases (IBDs). The use of bacteria-free, probiotic-derived compounds...
|
|
|
US20080172751 |
Agent Comprising Fgf2 as an Effective Ingredient For Treatment or Prevention of Asthma and Chronic Obstructive Pulmonary Disease
The present invention relates an agent comprising FGF2 (Fibroblast Growth Factor-2 or basic Fibroblast Growth Factor(bFGF)) as an effective ingredient for treatment or prevention of Asthma and...
|
|
|
US20080044403 |
Immune Markers Used for Diagnosis and Therapy in Connection With Transplant Reactions
The invention relates to immune markers for detecting inflammations, immune reactions, and particularly transplant tolerance or transplant reactions, a method for detecting transplant reactions or...
|
|
|
US20050192226 |
Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants
ATIII is a serine proteinase inhibitor (serpin) with anti-coagulant, anti-inflammatory, anti-proliferative and anti-angiogenic properties. The invention features methods of treating a subject...
|
|
|
US20110166071 |
METHOD FOR SYNTHESIZING THYMOSINS
The invention relates to a method for obtaining thymosins and/or the pharmaceutically acceptable salts thereof by means of solid-phase synthesis on polymeric supports, which comprises the steps of...
|
|
|
US20080167248 |
Anti-Aging Effects Of Substance P
Substance P or its analogs can be administered to humans to reverse or retard the course of various biological processes related to aging in adults. Reversal or retardation can be observed in hair...
|
|
|
US20080081064 |
Implantable Medical Device with Apertures for Delivery of Bioactive Agents
An implantable medical device for the release of bioactive agents at desired rates is described. The device includes a body member with two or more aperture sets and an inner space. The bioactive...
|
|
|
US20070004620 |
Fp receptor antagonists or pgf2 alpha antagonists for treating pathological conditions of the uterus
A method of treating or preventing a pathological condition of the uterus in an female individual, the method comprising administering to the individual at least one agent that prevents PGF2α, ...
|
|
|
US20120020991 |
PRODOMAIN MODULATORS OF ADAM 10
The presently disclosed subject matter discloses isolated ADAM 10 modulating peptides and related compounds useful for studying the biological functions of ADAM 10 and for the treatment of diseases...
|
|
|
US20060229237 |
Treatment of gastrointestinal distress
A composition and method for treating and/or preventing acute and chronic gastrointestinal distress including nausea, vomiting, lactose intolerance, obstructive symptoms, diarrhea, mucositis,...
|
|
|
US20120220526 |
Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and other Disorders
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a...
|
|
|
US20070178159 |
In-Situ Forming Porous Scaffold
A composition includes a viscous gel formed from a combination of a biodegradable polymer and a biocompatible solvent. The composition also includes a hydrophilic porogen, which may be incorporated...
|
|
|
US20120277155 |
THERAPY FOR KIDNEY DISEASE AND/OR HEART FAILURE
Medical systems and methods for treating kidney disease alone, heart failure alone, chronic kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and...
|
|
|
US20100183598 |
METHODS OF TREATING CARDIOVASCULAR DISORDERS
Disclosed herein, in certain embodiments, is a method for treating a cardiovascular disorder. In some embodiments, the method comprises co-administering an inhibitor of inflammation and an agent...
|
|
|
US20060153894 |
Multi-compartment delivery system
This invention provides devices designed to effectively deliver multiple biological entities in combination for tissue engineering. In particular, the present invention provides devices capable of...
|
|
|
US20120077747 |
FISH-DERIVED PROTEIN LYSATE, AND USES THEREOF AS IMMUNOMODULATORY AND/OR ANTI-INFLAMMATORY AGENT
A peptide-comprising extract derived from fish is described. Also disclosed is a process for obtaining a peptide-comprising extract derived from fish, as well as an extract obtained by this...
|
|
|
US20110136737 |
DPP-IV Resistant GIP Hybrid Polypeptides with Selectable Properties
The Present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and...
|
|
|
US20070172517 |
Compositions capable of facilitation penetration across a biological barrier
This invention relates to novel pharmaceutical compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of...
|
|
|
US20050130924 |
Antisense inhibition via RNAse H-independent reduction in mRNA
The present invention provides compositions and methods for reducing levels of a preselected mRNA, using antisense compounds targeted to a splice site or a region up to 50 nucleobases upstream of...
|
|
|
US20100075908 |
MIMOTOPE RECEPTORS AND INHIBITORS FOR PLATELET-PLATELET AND PLATELET-ENDOTHELIUM INTERACTIONS
It is provided mimotope receptors and inhibitors that employ peptide mimics that mimic the shape and function of natural receptors and ligands, thus providing synthetic binding sites for ligands...
|
|
|
US20060140950 |
Uses of mammalian cytokine; related reagents
Provided are methods of treatment for inflammatory and autoimmune disorders of the central nervous system and gastrointestinal tract. Also provided are methods of diagnosis.
|
|
|
US20050025807 |
Cured porous calcium phosphate material and uses thereof
There are provided a cured porous calcium phosphate material, an alternative living body tissue material, a tissue engineering scaffold and a drug support medium for DDS using the same. The cured...
|
|
|
US20070191275 |
Method of treating, preventing, inhibiting or reducing damage to cardiac tissue with thymosin beta 4 fragments
A method of treatment for promoting regeneration or repair a damaged cardiovascular tissue, or for preventing damage to cardiovascular tissue, includes administering to the tissue a damage-treating...
|
|
|
US20060128611 |
Composition for enzyme inhibition
Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these...
|
|
|
US20120087891 |
Reversible Gel-forming Compositions for Controlled Delivery of Bioactive Substances
The present invention relates biomedically useful compositions containing bioactive agents and biodegradable carbohydrate polyethers that exhibit reverse thermogelation properties in aqueous media....
|
|
|
US20070224165 |
Neuroprotective Effects of Gly-Pro-Glu Following Intravenous Infusion
Gly-Pro-Glu (GPE) is rapidly metabolized in vivo. We found that GPE infusion elicits potent and consistent neuroprotection in all brain regions examined, and in certain embodiments, the effects...
|
|
|
US20060083714 |
Combination of a pde iv inhibitor and a tnf-alpha antagonist
The subject invention relates to therapeutic combinations and methods for the treatment of inflammatory conditions and diseases. Particularly the present invention relates to treatments and methods...
|
|
|
US20060035851 |
Use of hmgb1 in the treatment of tissue damage and or to promote tissue repair
It is described a composition comprising an effective amount of the HMGBl protein or functional parts thereof, of HMGBl expressing vectors, for the treatment of tissue damage and/or to promote...
|
|
|
US20120014914 |
INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASES
The present invention relates to compounds of formula I: or a pharmaceutically acceptable salt, or mixtures thereof, that inhibit serine protease activity, particularly the activity of hepatitis C...
|
|
|
US20060094651 |
Formulations and methods of production of FGF-20
The present invention provides improved formulations comprising FGF-20, its fragments, derivatives, variants, homologs, analogs, or a combination thereof, and improved methods for production.
|
|
|
US20050215479 |
Diagnostic indicator of thymic function
The present disclosure provides a method for determining whether a patient's immune system can be modified through stimulation of thymus function. In one embodiment, sex steroids are ablated in the...
|
|
|
US20110195020 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses
The present invention concerns methods and compositions for making and using bioactive assemblies of defined compositions, which may have multiple functionalities and/or binding specificities. In...
|
|
|
US20080145335 |
Analogs of Glycyl-Prolyl-Glutamate
Embodiments of this invention include novel analogs of Glycyl-Prolyl-Glutamate (GPE) and compositions containing such analogs of GPE. Of these, certain analogs have modified proline residues. Other...
|
|
|
US20130072431 |
CARDIOVASCULAR THERAPEUTICS
Compounds and compositions comprising a B-type natriuretic signal peptide fragment agent, and methods of use thereof, are provided for the treatment or prevention of cardiovascular diseases,...
|
|
|
US20120308570 |
METHODS FOR TREATING DISEASES
The present invention relates to methods of modulating the level of inducible nitric oxide synthase (iNOS) in a cell which comprises administering to the cell a compound which modulates binding of...
|
|
|
US20080057096 |
Biocompatible stent
A biocompatible stent with a fluoride-containing hydrophilic water insoluble crosslinked resin layer. A therapeutic substance-containing layer may also be included. A method of making a...
|
|
|
US20070015257 |
Alpha-MSH related compounds and methods of use
The invention provides polypeptides containing α-MSH that can be used to treat diseases characterized by inflammation and/or autoimmunity. Also included in the invention are α-MSH analogs and n...
|
|
|
US20050123507 |
Formulations for coated microprojections having controlled solubility
The invention provides for a formulation for coating one or more microprojections using a non-volatile counterion to improve solubility of a biologically active agent. The invention also includes...
|
|
|
US20110144020 |
TREATMENT OF INFECTIONS AND OTHER DISORDERS
Microbial infections including anthrax infection, and gastrointestinal disorders, are treated or prevented by administration of an actin-sequestering peptide including amino acid sequence LKKTET,...
|
|
|
US20070105781 |
Inhibitors of serine proteases
This invention relates to compounds of formula I: or a pharmaceutically acceptable salt or mixtures thereof wherein C* represents a diastereomeric carbon comprising a mixture of R and S isomers...
|
|
|
US20080014252 |
TOPICAL COMPOSITIONS WITH LONG LASTING EFFECT
Topical pharmaceutical formulations and compositions for transdermal delivery of a variety of active agents are described. The formulations and compositions are formulated to provide a long lasting...
|
|
|
US20080064642 |
Peptidic And Peptidoid Bradykinin B1 Receptor Antagonists And Uses Thereof
The present invention provides for new peptidic and peptidoid Bradykinin B1 receptor antagonists of formula (1) having good to excellent affinities and selectivity for the BKB1 receptor, and...
|
|
|
US20070042945 |
Nouvelles compositions et methods de traitement du psoriasis
The present invention relates to compositions and methods useful for the diagnosis and treatment of psoriasis.
|
|
|
US20070184019 |
Pharmaceutical composition comprising an active principal and sulphobetaine
The present invention relates to the pharmaceutical composition comprising a non-detergent sulphobetaine (NDSB).
|
|
|
US20070249538 |
Soluble TNF receptors and their use in treatment of disease
The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of...
|
|
|
US20080089923 |
Biodegradable ocular implants and methods for treating ocular conditions
Biodegradable ocular implants are described. The ocular implants include a bioactive agent that can be released within the eye to treat an ocular condition or indication. The implants can be used...
|
|
|
US20120238498 |
Agent for the treatment of alopecia
It is an object of the present invention to provide a new agent for the treatment of alopecia, the agent being not only effective and safe for, in particular, alopecia areata, androgenetic alopecia...
|
|
|
US20120220528 |
SYSTEMS AND METHODS FOR THERAPY OF KIDNEY DISEASE AND/OR HEART FAILURE USING CHIMERIC NATRIURETIC PEPTIDES
Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and methods are...
|