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US20120190611 METHOD FOR TREATMENT OF INFLAMMATORY DISEASE AND DISORDER  
The present disclosure provides a method, composition and kit for treatment of inflammatory disease and disorder using PKC isoform modulators. Exemplary modulators include inhibitors of PKC-alpha,...
US20080138440 Methods of diagnosing and alleviating gadolinium toxicity  
The present invention relates to novel methods of treating or reducing the likelihood of developing gadolinium toxicity by administering to a patient a metal chelator before, concurrently with, or...
US20140194357 Modified Relaxin Polypeptides and Their Uses  
Modified relaxin polypeptides and their uses thereof are provided
US20120046229 MODIFIED RELAXIN POLYPEPTIDES AND THEIR USES  
Modified relaxin polypeptides and their uses thereof are provided
US20120225057 METHODS AND COMPOSITIONS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES  
Compounds of the present invention, alone and in combination with other active agents, find utility in the treatment of hyperproliferative diseases, mammalian cancers and especially human cancers...
US20070032409 Bradykinin receptor antagonists and uses thereof  
The present invention regards bradykinin receptor antagonists for treatment of a medical condition. In particular, the medical condition follows cardiopulmonary bypass. In specific embodiments,...
US20060257359 Modifying macrophage phenotype for treatment of disease  
The present invention provides compositions and methods for modulating one or more phenotypes of a macrophage-related cell, e.g., a macrophage. The invention further provides methods of treating...
US20090012005 Use of an angiotensin IV antagonist to treat insulin resistance or cardiovascular risk related to metabolic syndrome  
The present invention relates to the use of an angiotensin IV antagonist that decreases the effects on angiotensinogen expression of angiotensin IV in vascular smooth muscle cells for preparing a...
US20080159983 Interleukin-15 antagonists for the treatment of anemia  
The present invention relates to methods and compositions for the prevention and treatment of anemia. Anemia is characterized by a deficiency in red blood cells (RBCs) or hemoglobin, thereby...
US20080038317 Therapeutic Lacrimal Canalicular Inserts And Related Methods  
Lacrimal canalicular inserts include a polymeric component and a therapeutic component. The therapeutic component is released from the inserts for extended periods of time, such as for more than...
US20110223230 HYDROGEL FORMULATIONS  
A polymeric prodrug composition including a hydrogel, a biologically active moiety and a reversible prodrug linker. The prodrug linker covalently links the hydrogel and the biologically active...
US20110257087 Protein Hydrolysate Compositions Having Enhanced CCK Releasing Activity  
The present invention provides protein hydrolysate compositions having enhanced cholecystokinin (CCK) releasing activity that can be used to promote satiety.
US20100016232 Treatment Of Inflammatory Diseases With Mammal Beta Defensins  
The present invention relates to suppression of TNF-alpha activity with mammal beta defensins, which has utility in the treatment of pathological conditions associated with tumor necrosis factor...
US20100166789 PROTEINS FOR USE IN DIAGNOSING AND TREATING INFECTION AND DISEASE  
The present invention describes compositions of thymus derived peptides and uses therefore in diagnostic methods and for the treatment of diseases associated with reduced T helper cell counts,...
US20070065456 Nutritional supplements  
Nutritional supplement formulations are disclosed, such as nutritional supplement formulations that include Wasabia japonica. Methods for using the same to supplement a human diet are also disclosed.
US20140179606 LEFT VENTRICULAR DIASTOLIC FUNCTION IMPROVING AGENT  
An agent for treating heart failure, which improves left ventricular diastolic function itself without depending on the diuretic effect or vasodilation effect; controls the pathological condition...
US20080095819 Composition and Methods for Promoting Wound Healing and tissue Regeneration  
Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.
US20080175845 Methods for treating target joints in inflammatory arthritis using AAV vectors encoding a TNF antagonist  
The present invention provides methods for treating inflammatory arthritis in an individual, comprising administering to the individual an effective amount of AAV (rAAV) vector comprising a...
US20050079176 Treating stress response with chemokine receptor ccr5 modulators  
The use of chemokine receptor CCR5 modulators (e.g., CCR5 antagonists) is disclosed for the treatment or prevention of stress response (e.g., fever) in a subject resulting from surgery, infection...
US20080160025 Use of Calcitonin as Combined Treatment Therapy for the Management of Inflammatory Disease Conditions  
The use is provided of a calcitonin in the preparation of a medicament for the treatment of an inflammatory disease or condition. The calcitonin may be selected from the group consisting of human,...
US20060057105 Methods of treating ocular inflammation and allergy  
The present specification discloses methods of treating ocular inflammation and ocular allergy through the administration of interferon inhibitors to a mammal, including a human, in need thereof.
US20100120665 TREATMENT OF DISEASES CHARACTERIZED BY INFLAMMATION  
The invention provides, in part, methods, nucleic acids, vectors, proteins and binding molecules that can be used to modulate a pathway such as a complement pathway. These methods and compositions...
US20080075657 BIOPOLYMER SYSTEM FOR TISSUE SEALING  
The invention provides a method of treating degenerative disc disease and discogenic pain by disposing a hydrogel tissue sealant within the intervertebral disc, where the hydrogel fills voids and...
US20070077258 ADMINISTRATION OF GLUTATHIONE (REDUCED) VIA INTRAVENOUS OR ENCAPSULATED IN LIPOSOME FOR THE AMELIORATION OF TNF-alpha EFFECTS AND FLU-LIKE VIRAL SYMPTOMS AND TREATMENT AND PREVENTION OF VIRUS  
The invention is a method of treatment of the symptoms related to inflammation that accompanies the release of Tumor Necrosis Factor-alpha in diseases such as viral infection such as those...
US20080299138 Toll-Like Receptor 3 Modulators and Uses Thereof  
Modulators of TLR3 activity and their use are disclosed.
US20080139451 Compositions for Treating Ocular Surface Pathologies  
The invention concerns compositions and methods for treating and/or preventing ocular pathologies. The invention also concerns compositions and methods enabling the regulation of paracellular...
US20060078571 Methods for treating inflammation pain  
The present invention relates to methods for treating neurogenic inflammation pain. The methods include administering an effective amount of a composition which includes a botulinum toxin component...
US20070098685 Methods and kits to treat chronic inflammatory immune diseases by administering a proteasome inhibitor and an interleukin 2 receptor agonist  
Methods and kits for treatment of immune diseases with an IL2 receptor agonist and a proteasome inhibitor are provided.
US20060252681 Pain relief agents  
The present invention concerns the use of a heat shock polypeptide and/or an encoding nucleic acid sequence in the manufacture of a medicament for use in the relief of pain. In particular the...
US20070123460 Probiotic compounds from Lactobacillus GG and uses therefor  
The invention provides methods and compositions for the treatment of inflammatory disorders, such as inflammatory bowel diseases (IBDs). The use of bacteria-free, probiotic-derived compounds...
US20080172751 Agent Comprising Fgf2 as an Effective Ingredient For Treatment or Prevention of Asthma and Chronic Obstructive Pulmonary Disease  
The present invention relates an agent comprising FGF2 (Fibroblast Growth Factor-2 or basic Fibroblast Growth Factor(bFGF)) as an effective ingredient for treatment or prevention of Asthma and...
US20080044403 Immune Markers Used for Diagnosis and Therapy in Connection With Transplant Reactions  
The invention relates to immune markers for detecting inflammations, immune reactions, and particularly transplant tolerance or transplant reactions, a method for detecting transplant reactions or...
US20050192226 Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants  
ATIII is a serine proteinase inhibitor (serpin) with anti-coagulant, anti-inflammatory, anti-proliferative and anti-angiogenic properties. The invention features methods of treating a subject...
US20110166071 METHOD FOR SYNTHESIZING THYMOSINS  
The invention relates to a method for obtaining thymosins and/or the pharmaceutically acceptable salts thereof by means of solid-phase synthesis on polymeric supports, which comprises the steps of...
US20080167248 Anti-Aging Effects Of Substance P  
Substance P or its analogs can be administered to humans to reverse or retard the course of various biological processes related to aging in adults. Reversal or retardation can be observed in hair...
US20080081064 Implantable Medical Device with Apertures for Delivery of Bioactive Agents  
An implantable medical device for the release of bioactive agents at desired rates is described. The device includes a body member with two or more aperture sets and an inner space. The bioactive...
US20070004620 Fp receptor antagonists or pgf2 alpha antagonists for treating pathological conditions of the uterus  
A method of treating or preventing a pathological condition of the uterus in an female individual, the method comprising administering to the individual at least one agent that prevents PGF2α, ...
US20120020991 PRODOMAIN MODULATORS OF ADAM 10  
The presently disclosed subject matter discloses isolated ADAM 10 modulating peptides and related compounds useful for studying the biological functions of ADAM 10 and for the treatment of diseases...
US20130309201 OLIGONUCLEOTIDE CHELATE COMPLEX - POLYPEPTIDE COMPOSITIONS AND METHODS  
It is disclosed a pharmaceutical composition containing an oligonuclelotide chelate complex and at least one polypeptide or pegylated polypeptide. The present disclosure also describes additional...
US20060229237 Treatment of gastrointestinal distress  
A composition and method for treating and/or preventing acute and chronic gastrointestinal distress including nausea, vomiting, lactose intolerance, obstructive symptoms, diarrhea, mucositis,...
US20120220526 Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and other Disorders  
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a...
US20070178159 In-Situ Forming Porous Scaffold  
A composition includes a viscous gel formed from a combination of a biodegradable polymer and a biocompatible solvent. The composition also includes a hydrophilic porogen, which may be incorporated...
US20120277155 THERAPY FOR KIDNEY DISEASE AND/OR HEART FAILURE  
Medical systems and methods for treating kidney disease alone, heart failure alone, chronic kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and...
US20100183598 METHODS OF TREATING CARDIOVASCULAR DISORDERS  
Disclosed herein, in certain embodiments, is a method for treating a cardiovascular disorder. In some embodiments, the method comprises co-administering an inhibitor of inflammation and an agent...
US20060153894 Multi-compartment delivery system  
This invention provides devices designed to effectively deliver multiple biological entities in combination for tissue engineering. In particular, the present invention provides devices capable of...
US20120077747 FISH-DERIVED PROTEIN LYSATE, AND USES THEREOF AS IMMUNOMODULATORY AND/OR ANTI-INFLAMMATORY AGENT  
A peptide-comprising extract derived from fish is described. Also disclosed is a process for obtaining a peptide-comprising extract derived from fish, as well as an extract obtained by this...
US20110136737 DPP-IV Resistant GIP Hybrid Polypeptides with Selectable Properties  
The Present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and...
US20070172517 Compositions capable of facilitation penetration across a biological barrier  
This invention relates to novel pharmaceutical compositions capable of facilitating penetration of at least one effector across biological barriers. The invention also relates to methods of...
US20050130924 Antisense inhibition via RNAse H-independent reduction in mRNA  
The present invention provides compositions and methods for reducing levels of a preselected mRNA, using antisense compounds targeted to a splice site or a region up to 50 nucleobases upstream of...
US20100075908 MIMOTOPE RECEPTORS AND INHIBITORS FOR PLATELET-PLATELET AND PLATELET-ENDOTHELIUM INTERACTIONS  
It is provided mimotope receptors and inhibitors that employ peptide mimics that mimic the shape and function of natural receptors and ligands, thus providing synthetic binding sites for ligands...