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US20120283117 DETERMINATION OF EOSINOPHILIC ESOPHAGITIS  
Eosinophilic esophagitis (EE), an emerging disorder with poorly understood pathogenesis, was examined. Esophageal tissue was analyzed by a genome wide microarray expression analysis. EE patients...
US20140011699 Systems and Methods for Diagnosing a Predisposition to Develop Cancer  
Systems, methods, and computer readable media for diagnosing or characterizing a genetic predisposition to develop cancer are provided. Nucleic acids comprising a germline nucleic acid sequence...
US20150080257 METHOD FOR EVALUATING URATE TRANSPORT-RELATED DISEASE FACTOR AND INFLAMMATION-RELATED DISEASE FACTOR  
A method and evaluation kit are provided, in which a high-capacity urate transporter is identified to assist in the early treatment and prevention of urate transport-related disease and...
US20150080248 METHODS FOR ISOLATING PROTEINS  
The invention generally relates to methods for isolating proteins. In certain aspects, methods of the invention involve preparing a plurality of sample preparations, each preparation including one...
US20140163075 MODULATION OF THE UBIQUITIN-PROTEASOME SYSTEM (UPS)  
The invention relates to the field of 26S proteasome inhibition, activation and modulation and to identify compounds which activate 26S proteasome in live cells and a method of treating autoimmune...
US20120329663 14-3-3 sigma as a Biomarker of Basal Cancer  
Methods and compositions for using 14-3-3sigma gene and protein as a highly sensitive and specific basal breast cancer biomarker, which when present, correlates with metastasis and poor outcome in...
US20140296085 METHOD OF PREDICTING BREAST CANCER PROGNOSIS  
The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts,...
US20130130928 METHODS FOR PREDICTING OR MONITORING WHETHER A PATIENT AFFECTED BY A CANCER IS RESPONSIVE TO A TREATMENT WITH A MOLECULE OF THE TAXOID FAMILY  
The present invention concerns in vitro methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family based on a...
US20110177970 METHODS FOR PREDICTING OR MONITORING WHETHER A PATIENT AFFECTED BY A CANCER IS RESPONSIVE TO A TREATMENT WITH A MOLECULE OF THE TAXOID FAMILY  
The present invention concerns in vitro methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family based on a...
US20150133323 METHOD FOR CHARACTERIZING CIRCULATING TUMOR CELLS, AND USE THEREOF IN DIAGNOSIS  
Disclosed is a method for characterization, in a biological sample, of circulating tumour cells (CTCs) bearing at least one marker characteristic of the tumorous nature of the cell, the marker...
US20110213009 ADFP MODULATORS IN THE TREATMENT OF ACNE, OF SEBORRHOEIC DERMATITIS OR OF HYPERSEBORRHOEA  
An in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with...
US20140323342 Methods and Compositions for the Treatment and Diagnosis of Bladder Cancer  
The invention provides methods, compositions and kits for the detection and treatment of bladder cancer.
US20110306503 TEMPLATE-DEPENDENT NUCLEIC ACID POLYMERIZATION USING OLIGONUCLEOTIDE TRIPHOSPHATES BUILDING BLOCKS  
A novel use of a template-dependent polymerase. The novel use is effected by employing the template-dependent polymerase for incorporating at least one oligonucleotide triphosphate onto a nascent...
US20130210645 PERSONALIZED TUMOR BIOMARKERS  
Clinical management of human cancer is dependent on the accurate monitoring of residual and recurrent tumors. We have developed a method, called personalized analysis of rearranged ends (PARE),...
US20140213465 PLAQUE ARRAY METHODS AND COMPOSITIONS FOR FORMING AND DETECTING PLAQUES  
Provided herein are methods and compositions for the in vitro formation of an array of plaque particles for use in biological assays, diagnosis, drug discovery and drug development. More...
US20140194317 BIOMARKERS FOR THE DETECTION OF HEAD AND NECK TUMORS  
A method of detecting the presence of specific human papilloma virus and host cell biomarkers associated with head and neck tumors in biological samples, like saliva, blood or biopsy tissue,...
US20120278909 COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE  
In alternative embodiments, the invention provides nucleic acid sequences that are genetic polymorphic variations of the human TMEM216 gene, and TMEM216 polypeptide encoded by these variant...
US20150152507 BIOMARKERS FOR PROSTATE CANCER  
The present application concerns methods and tools for diagnosing prostate cancer and furthermore concerns methods and tools for prognosing disease progression of prostate cancer. The method...
US20140011812 Methods of Treating Inflammation  
The present invention relates to methods of decreasing inflammation by inhibiting polo-like kinase (PlK)
US20150086581 Fast Diagnosis and Personalized Treatment for Acne  
Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne...
US20140141994 Protein Scaffolds  
The invention provides protein scaffolds and methods of preparing, screening, engineering and using such protein scaffolds.
US20130143755 Protein and Gene Biomarkers for Rejection of Organ Transplants  
Aspects of the present invention include methods for determining a transplant category of a subject having a transplant. Common mechanisms of rejection injury are uncovered across different tissue...
US20100292096 STRAIN AND SPECIES-SPECIFIC BORRELIA PROTEIN ARRAY  
Methods of assessing a sample for the presence of antibodies to certain proteins of Borrelia burgdorferi, are described, as are methods of diagnosing Lyme disease. Microarrays of proteins of...
US20110230369 METHOD FOR SCREENING COMPOUNDS FOR THEIR ABILITY TO INCREASE RIGIDITY OF RED BLOOD CELLS INFECTED BY A PROTOZOAN PARASITE OF THE GENUS PLASMODIUM, METHOD FOR FILTERING RED BLOOD CELLS, AND APPLICATION THEREOF  
The invention relates to a method for screening compounds for their ability to increase rigidity of red blood cells (RBCs) infected by a protozoan parasite of the genus Plasmodium and in...
US20110144076 PRETERM DELIVERY DIAGNOSTIC ASSAY  
The present invention in one aspect relates generally to the identification, provision and use of a plurality of biomarkers to provide risk assessment of a woman for preterm delivery, and products...
US20100331833 IN-VITRO DEVICE MONITORING DURING MINIMALLY INVASIVE ABLATION THERAPY  
A method and apparatus for monitoring and controlling interventional therapy is described, where the interventional therapy results in the destruction of tissue and the release of chemical...
US20120220482 COMPOSITIONS AND METHODS FOR SCREENING PEPTOID LIBRARIES  
Certain embodiments are directed to methods for screening synthetic libraries and characterizing the resultant hits that combines many of the attractive features of bead library screening and...
US20150176072 MOLECULAR MALIGNANCY IN MELANOCYTIC LESIONS  
Disclosed are methods for determining whether a melanocyte-containing sample (such as a nevus or other pigmented lesion) is benign or a primary melanoma. These methods can include detecting (at...
US20150057189 IN VIVO TRANSDUCTION WITH A CHIMERIC AAV CAPSID PROTEIN  
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided.
US20110288151 METHODS OF CHARACTERIZING BREAST CANCER AND IDENTIFYING TREATMENTS FOR SAME  
This application describes antibodies to P-Rex 1, and methods of detecting breast cancer, and methods of treatments for the same.
US20150024970 KIDNEY CELL CARCINOMA  
The process for the diagnosis of a renal cell carcinoma comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, wherein said...
US20100303832 GENES AND POLYMORPHISMS ASSOCIATED WITH AMD  
The invention relates to genes, gene polymorphisms, and genetic profiles associated with an elevated or a reduced risk of alternative complement cascade deregulation disease such as AMD. The...
US20110082046 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE  
The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and...
US20120302572 USE OF EMT GENE SIGNATURES IN CANCER DRUG DISCOVERY, DIAGNOSTICS, AND TREATMENT  
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase...
US20150011419 SYSTEMS AND METHODS FOR CHARACTERIZING LUPUS ERYTHEMATOSUS  
The present invention provides systems and methods for characterizing biological markers in the urine of systemic lupus erythematosus (SLE) subjects. In particular, the present invention relates...
US20140031251 METHODS OF CLASSIFYING HUMAN SUBJECTS WITH REGARD TO CANCER PROGNOSIS  
In one aspect, methods, markers, and expression signatures are disclosed for assessing the degree to which a cell sample has epithelial cell-like properties or mesenchymal cell-like properties. In...
US20140342931 METHOD FOR PREDICTING RESPONSE TO ENDOCRINE THERAPY  
The present invention relates to a method for predicting the response of a patient diagnosed with breast cancer to treatment with an endocrine therapy drug, comprising the steps of: (a) measuring...
US20110251087 PROGNOSTIC AND DIAGNOSTIC METHOD FOR CANCER THERAPY  
The present invention relates to methods for the diagnosis and prognosis of aggressive forms of cancer using a combination of gene expression signatures.
US20140221506 Methods of Diagnosing Neuropathic Pain  
The invention includes compositions and methods useful for the diagnosis, assessment, and characterization of neuropathic pain in a subject in need thereof, based upon the expression level of at...
US20110201512 Biomarkers Indicative of Colon Cancer and Metastasis and Diagnosis and Screening Therapeutics Using the Same  
The present invention relates to a method for detecting a colon cancer in a human, comprising the steps of: (a) providing a biological sample from the human; and (b) detecting the level of a ATAD2...
US20140243219 METHODS AND SIGNATURES FOR OROPHARYNGEAL CANCER PROGNOSIS  
Methods for determining the prognosis of a subject with oropharyngeal squamous cell carcinoma are described, as well as miRNAs and panels of prognostic miRNAs that are used in the methods.
US20110065601 IDENTIFICATION OF DISCRIMINANT PROTEINS THROUGH ANTIBODY PROFILING, METHODS AND APPARATUS FOR IDENTIFYING AN INDIVIDUAL  
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample...
US20110065594 Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual  
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample...
US20140086911 Methods and Products for Predicting CMTC Class and Prognosis in Breast Cancer Patients  
Provided herein are products, uses and method classifying a subject afflicted with breast cancer according to a ClinicoMolecular Triad Classification (CMTC)-1, CMTC-2 or CMTC-3 class. The method...
US20130045884 MEANS AND METHODS FOR DIAGNOSING PANCREATIC CANCER  
The present invention pertains to the field of cancer diagnosis. Specifically, it relates to a method for diagnosing pancreas cancer in a subject comprising the steps of determining in a sample of...
US20120029056 DIFFERENTIALLY EXPRESSED MICRORNAS AS BIOMARKERS FOR THE DIAGNOSIS AND TREATMENT OF SJÖGREN'S SYNDROME  
The identification of differentially expressed microRNAs in patients with Sjögren's syndrome is disclosed herein. Provided is a method of diagnosing a subject as having Sjögren's syndrome by...
US20100304412 METHODS FOR DETERMINING THE RISK OF PRENATAL COMPLICATIONS  
The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain...
US20120289420 MICRORNA BIOMARKERS FOR AIRWAY DISEASES  
The present invention provides miRNA biomarkers useful for diagnosis, prognosis, and/or treatment of airway diseases such as asthma, asthma exacerbation and nasal polyps.
US20120220469 TOXICITY TYPING USING LIVER STEM CELLS  
This invention provides methods and systems for identifying and typing toxicity of chemical compositions, as well as for screening new compositions for toxicity. The invention involves detecting...
US20150160230 METHODS OF PREDICTING AND DECREASING THE RISK OF PRE-TERM BIRTH  
Provided are methods for predicting the risk of pre-term birth in a pregnant subject, for identifying a subject having an increased risk of pre-term birth, for selecting a subject for...