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US20140194317 BIOMARKERS FOR THE DETECTION OF HEAD AND NECK TUMORS  
A method of detecting the presence of specific human papilloma virus and host cell biomarkers associated with head and neck tumors in biological samples, like saliva, blood or biopsy tissue,...
US20120278909 COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE  
In alternative embodiments, the invention provides nucleic acid sequences that are genetic polymorphic variations of the human TMEM216 gene, and TMEM216 polypeptide encoded by these variant...
US20140011812 Methods of Treating Inflammation  
The present invention relates to methods of decreasing inflammation by inhibiting polo-like kinase (PlK)
US20150086581 Fast Diagnosis and Personalized Treatment for Acne  
Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne...
US20140141994 Protein Scaffolds  
The invention provides protein scaffolds and methods of preparing, screening, engineering and using such protein scaffolds.
US20130143755 Protein and Gene Biomarkers for Rejection of Organ Transplants  
Aspects of the present invention include methods for determining a transplant category of a subject having a transplant. Common mechanisms of rejection injury are uncovered across different tissue...
US20100292096 STRAIN AND SPECIES-SPECIFIC BORRELIA PROTEIN ARRAY  
Methods of assessing a sample for the presence of antibodies to certain proteins of Borrelia burgdorferi, are described, as are methods of diagnosing Lyme disease. Microarrays of proteins of...
US20110230369 METHOD FOR SCREENING COMPOUNDS FOR THEIR ABILITY TO INCREASE RIGIDITY OF RED BLOOD CELLS INFECTED BY A PROTOZOAN PARASITE OF THE GENUS PLASMODIUM, METHOD FOR FILTERING RED BLOOD CELLS, AND APPLICATION THEREOF  
The invention relates to a method for screening compounds for their ability to increase rigidity of red blood cells (RBCs) infected by a protozoan parasite of the genus Plasmodium and in...
US20110144076 PRETERM DELIVERY DIAGNOSTIC ASSAY  
The present invention in one aspect relates generally to the identification, provision and use of a plurality of biomarkers to provide risk assessment of a woman for preterm delivery, and products...
US20100331833 IN-VITRO DEVICE MONITORING DURING MINIMALLY INVASIVE ABLATION THERAPY  
A method and apparatus for monitoring and controlling interventional therapy is described, where the interventional therapy results in the destruction of tissue and the release of chemical...
US20120220482 COMPOSITIONS AND METHODS FOR SCREENING PEPTOID LIBRARIES  
Certain embodiments are directed to methods for screening synthetic libraries and characterizing the resultant hits that combines many of the attractive features of bead library screening and...
US20150057189 IN VIVO TRANSDUCTION WITH A CHIMERIC AAV CAPSID PROTEIN  
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided.
US20110288151 METHODS OF CHARACTERIZING BREAST CANCER AND IDENTIFYING TREATMENTS FOR SAME  
This application describes antibodies to P-Rex 1, and methods of detecting breast cancer, and methods of treatments for the same.
US20150024970 KIDNEY CELL CARCINOMA  
The process for the diagnosis of a renal cell carcinoma comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, wherein said...
US20100303832 GENES AND POLYMORPHISMS ASSOCIATED WITH AMD  
The invention relates to genes, gene polymorphisms, and genetic profiles associated with an elevated or a reduced risk of alternative complement cascade deregulation disease such as AMD. The...
US20110082046 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE  
The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and...
US20120302572 USE OF EMT GENE SIGNATURES IN CANCER DRUG DISCOVERY, DIAGNOSTICS, AND TREATMENT  
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase...
US20150011419 SYSTEMS AND METHODS FOR CHARACTERIZING LUPUS ERYTHEMATOSUS  
The present invention provides systems and methods for characterizing biological markers in the urine of systemic lupus erythematosus (SLE) subjects. In particular, the present invention relates...
US20140031251 METHODS OF CLASSIFYING HUMAN SUBJECTS WITH REGARD TO CANCER PROGNOSIS  
In one aspect, methods, markers, and expression signatures are disclosed for assessing the degree to which a cell sample has epithelial cell-like properties or mesenchymal cell-like properties. In...
US20140342931 METHOD FOR PREDICTING RESPONSE TO ENDOCRINE THERAPY  
The present invention relates to a method for predicting the response of a patient diagnosed with breast cancer to treatment with an endocrine therapy drug, comprising the steps of: (a) measuring...
US20110251087 PROGNOSTIC AND DIAGNOSTIC METHOD FOR CANCER THERAPY  
The present invention relates to methods for the diagnosis and prognosis of aggressive forms of cancer using a combination of gene expression signatures.
US20140221506 Methods of Diagnosing Neuropathic Pain  
The invention includes compositions and methods useful for the diagnosis, assessment, and characterization of neuropathic pain in a subject in need thereof, based upon the expression level of at...
US20110201512 Biomarkers Indicative of Colon Cancer and Metastasis and Diagnosis and Screening Therapeutics Using the Same  
The present invention relates to a method for detecting a colon cancer in a human, comprising the steps of: (a) providing a biological sample from the human; and (b) detecting the level of a ATAD2...
US20140243219 METHODS AND SIGNATURES FOR OROPHARYNGEAL CANCER PROGNOSIS  
Methods for determining the prognosis of a subject with oropharyngeal squamous cell carcinoma are described, as well as miRNAs and panels of prognostic miRNAs that are used in the methods.
US20110065601 IDENTIFICATION OF DISCRIMINANT PROTEINS THROUGH ANTIBODY PROFILING, METHODS AND APPARATUS FOR IDENTIFYING AN INDIVIDUAL  
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample...
US20110065594 Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual  
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample...
US20140086911 Methods and Products for Predicting CMTC Class and Prognosis in Breast Cancer Patients  
Provided herein are products, uses and method classifying a subject afflicted with breast cancer according to a ClinicoMolecular Triad Classification (CMTC)-1, CMTC-2 or CMTC-3 class. The method...
US20130045884 MEANS AND METHODS FOR DIAGNOSING PANCREATIC CANCER  
The present invention pertains to the field of cancer diagnosis. Specifically, it relates to a method for diagnosing pancreas cancer in a subject comprising the steps of determining in a sample of...
US20120029056 DIFFERENTIALLY EXPRESSED MICRORNAS AS BIOMARKERS FOR THE DIAGNOSIS AND TREATMENT OF SJÖGREN'S SYNDROME  
The identification of differentially expressed microRNAs in patients with Sjögren's syndrome is disclosed herein. Provided is a method of diagnosing a subject as having Sjögren's syndrome by...
US20100304412 METHODS FOR DETERMINING THE RISK OF PRENATAL COMPLICATIONS  
The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain...
US20120289420 MICRORNA BIOMARKERS FOR AIRWAY DISEASES  
The present invention provides miRNA biomarkers useful for diagnosis, prognosis, and/or treatment of airway diseases such as asthma, asthma exacerbation and nasal polyps.
US20120220469 TOXICITY TYPING USING LIVER STEM CELLS  
This invention provides methods and systems for identifying and typing toxicity of chemical compositions, as well as for screening new compositions for toxicity. The invention involves detecting...
US20120277180 Cofactors and Methods for Use for Individuals  
Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of...
US20140010802 SYSTEMS AND METHODS FOR DIAGNOSING A PREDISPOSITION TO DEVELOP CANCER  
Systems, methods, and computer readable media for diagnosing or characterizing a genetic predisposition to develop cancer, including cancers of the BAP1 cancer syndrome, are provided. Nucleic...
US20140193406 METHODS USED IN IDENTIFYING GLIOBLASTOMA  
The invention encompasses methods and kits used in the identification of invasive glioblastoma based upon the expression of Akt1, Akt2, and Akt3. The methods and kits also allow prediction of...
US20140228246 ECM COMPOSITION, TUMOR MICROENVIRONMENT PLATFORM AND METHODS THEREOF  
The present disclosure relates to an Extra Cellular Matrix composition specific for cancer type and a tumor microenvironment platform for long term culturing of tumor tissue, wherein said...
US20140364337 ABSOLUTE QUANTITATION OF PROTEINS AND PROTEIN MODIFICATIONS BY MASS SPECTROMETRY WITH MULTIPLEXED INTERNAL STANDARDS  
A method for absolute protein or peptide quantitation by mass spectroscopy. A sample containing a protein or peptide of interest is prepared for mass spectroscopy analysis. The sample is subjected...
US20130171186 BROAD SPECTRUM INFLUENZA A NEUTRALIZING VACCINES AND D-PEPTIDIC COMPOUNDS, AND METHODS FOR MAKING AND USING THE SAME  
GB1 peptidic compounds that specifically bind to a hemagglutinin target protein, and libraries that include the same, as well as methods of making and using the same, are provided. Also provided...
US20120101002 Lung Cancer Biomarkers and Uses Thereof  
The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the detection and diagnosis of non-small cell lung cancer and general cancer. In one aspect, methods...
US20150105292 METHOD FOR ANALYSIS OF COMPOUND-BINDING ABILITY OF PROTEIN  
A method for analyzing a binding ability of protein to a compound, involves fractionating first and second groups of proteins into plural fractions using a carrier having the compound immobilized...
US20120004132 Detection of Nucleic Acids and Proteins  
Methods of detecting various types of nucleic acids, including methods of detecting two or more nucleic acids in multiplex branched-chain DNA assays, are provided. Detection assays may be...
US20150057190 ENCODING OF MICROCARRIERS  
Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the...
US20140206569 ENCODING OF MICROCARRIERS  
Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the...
US20150018233 METHODS AND G PROTEINS FOR SCREENING AND IDENTIFYING LIGANDS OF G PROTEIN-COUPLED RECEPTORS  
Abstract of the Disclosure Disclosed herein are methods and compounds for screening and identifying ligands of G protein-coupled receptors (GPCRs). Also disclosed are chimeric G proteins and...
US20140011696 BAP1 MUTATIONAL ANALYSIS IN DETERMINING SUSCEPTIBILITY TO, PROGNOSIS OF, AND TREATMENT OF MELANOCYTIC NEOPLASIA  
Methods and compositions for diagnosing and prognosing neoplasms, particularly malignant melanomas, and for identifying patients at high risk for melanocytic nevi and/or melanomas or other cancers...
US20110172123 Arrays  
Protein arrays that allow the analysis of differentially expressed proteins in parallel are disclosed. Methods for making such arrays, and their use for screening and/or evaluating the effect of...
US20140171339 METHODS AND KITS FOR DETECTING ADENOMAS, COLORECTAL CANCER, AND USES THEREOF  
This invention is directed to a novel method to detect adenomas and colorectal cancer (CRC) using a bacterial signature. Included in the invention are methods of (a) determining an individual's...
US20120322677 PREDICTING BENEFIT OF ANTI-CANCER THERAPY VIA ARRAY COMPARATIVE GENOMIC HYBRIDIZATION  
Array comparative genomic hybridization classifiers, arrays comprising the classifiers, and related methods of using the same for predicting the therapeutic efficacy of anti-cancer therapy by...
US20140206545 GENE EXPRESSION MARKERS FOR PREDICTION OF PATIENT RESPONSE TO CHEMOTHERAPY  
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a...
US20120040842 Gene Expression Markers for Prediction of Patient Response to Chemotherapy  
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a...