Match Document Document Title
US20120015832 METHODS, PANELS OF IDENTIFICATION MARKERS, AND KITS FOR IDENTIFYING FORENSIC SAMPLES  
Methods for identifying forensic samples using panels of markers and gene expression profiling, including without limitation, mRNA profiling, miRNA profiling, or both, are disclosed. Panels of...
US20150110897 Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer  
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to...
US20120065084 METHODS AND TOOLS FOR PREDICTING THE EFFICIENCY OF ANTHRACYCLINES IN CANCER  
A gene set, kit and method predict the efficiency of anthracyclines-based treatment of breast cancer.
US20110177957 Polymorphisms Associated With Age-Related Macular Degeneration And Methods For Evaluating Patient Risk  
The present invention provides for certain polynucleotide sequences that have been correlated to AMD. These polynucleotides are useful as diagnostics, and are preferably used to fabricate an...
US20110312509 BIOMARKERS DOWNREGULATED IN PROSTATE CANCER  
Biomarkers are identified by analyzing gene expression data using support vector machines (SVM), recursive feature elimination (RFE) and/or linear ridge regression classifiers to rank genes...
US20150099664 PROTEIN BIOMARKERS AND THERAPEUTIC TARGETS FOR AUTOIMMUNE AND ALLOIMMUNE DISEASES  
A method for characterizing the risk a subject will develop an autoimmune and/or alloimmune disease following tissue transplant includes obtaining a biological sample from the subject, wherein the...
US20120077767 MOLECULAR PREDICTORS OF FUNGAL INFECTION  
Methods for identifying fungal infection, assays for identifying genomic and protein markers of fungal infection, and methods for diagnosing the fungal infection. In one aspect, the method of...
US20110130324 METHODS FOR SYSTEMATIC CONTROL OF PROTEIN STABILITY  
Methods and compositions to control the stability of proteins with special emphasis on antibodies and proteins with antibody-like structures, e.g., having an “immunoglobulin-like” fold, are...
US20110105343 Systems Biology Approach Predicts Immunogenicity of Vaccines  
A major challenge in vaccinology is to prospectively determine vaccine efficacy. Disclosed herein are methods and compositions for identifying early expression “signatures” that predicted immune...
US20120129167 TRUNCATED CD20 PROTEIN, DELTACD20  
The present invention relates in particular to a protein from an alternative splicing of the gene encoding CD20, the nucleic acid sequences encoding the protein according to the invention, a...
US20130281502 POST-TREATMENT BREAST CANCER PROGNOSIS  
The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to extended treatment and cancer-free survival in a patient. In particular, the...
US20110130297 QUANTUM DOT-SENSORY ARRAY FOR BIOLOGICAL RECOGNITION  
The present invention provides a quantum dot-based biomolecule sensor array capable of differentiating the strain of a variety of biological molecules including bacteria, spores, fungi, viruses,...
US20110136679 Imprinted Array  
There is described a gene expression array comprising more than one imprinted gene and one or more control genes for the diagnosis of human epigenetic diseases resulting from assisted reproduction...
US20130203612 METHOD FOR ASSAYING SEPSIS IN HUMANS  
The present invention relates to a reliable method of prediction of sepsis in humans after a trauma, wherein the level of pancreatic stone protein/regenerating protein (PSP/reg) is determined in...
US20140024811 CANCER DETECTION  
Provided are methods of detecting cancer or pre-cancerous conditions in patients comprising assaying a patient sample for an elevated level of target molecules representative of expression of...
US20120041274 CANCER BIOMARKERS  
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
US20110224088 Biomarkers for subtypes of cervical cancer  
The present invention relates to biomarkers for chemoradioresistant subtypes of cervical cancer. In particular the present invention relates to a method for predicting a predisposition to a...
US20110306505 X-STR multiplex PCR amplification system  
The methods and compositions provided herein relate to the discovery of several new STR alleles and a 20-plex multiplex assay for markers found on the human X chromosome. These X-STR markers have...
US20120087862 ORGAN-SPECIFIC PROTEINS AND METHODS OF THEIR USE  
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific...
US20110070268 Method  
Methods for characterisation of patients as responders or non-responders to therapy based on differential expression of one or more genes are provided. Gene expression profiles, microarrays...
US20120129705 DIAGNOSTIC MARKERS FOR DETERMINING THE PREDISPOSITION TO THE DEVELOPMENT OF CERVICAL CANCER AND OLIGONUCLEOTIDES USED FOR THE DETERMINATION  
The present invention relates to a method for predisposition prediction of a subject to the development of cervical cancer and/or cancer precursors in an infection with the human papilloma virus...
US20110195848 GENE EXPRESSION AND BREAST CANCER  
This invention provides methods and reagents for determining breast cancer patient prognosis and/or diagnosis of tumor aggressiveness, disease-free survival times and reduced patient disease-free...
US20120142542 Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR  
Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are...
US20120064105 Engineered Type IV Pilin of Clostridium difficile  
The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected...
US20140148349 Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR  
Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are...
US20110136683 Systems and Methods for Expression-Based Discrimination of Distinct Clinical Disease States in Prostate Cancer  
A system for expression-based discrimination of distinct clinical disease states in prostate cancer is provided that is based on the identification of sets of gene transcripts, which are...
US20150079078 BIOMARKERS FOR TRIPLE NEGATIVE BREAST CANCER  
The present invention relates to biomarkers that are useful in the prognosis of triple negative breast cancer patients. The biomarkers may be used to select treatment and to determine whether a...
US20120220470 DIAGNOSTIC METHOD FOR DETECTING CANCER BY MEASURING AMOUNT OF A CYTOKINE LIKE IL-6  
The present invention relates to a diagnostic method for predicting the possible recurrence of tumours in cancer patients. The method comprises culturing blood cells from a patient suffering from...
US20120108447 METHODS OF PREDICTING CLINICAL OUTCOME IN MALIGNANT MELANOMA  
Malignant melanoma is the most aggressive type of skin cancer and currently accounts for more than 160.000 new cancer cases worldwide every year. Incidence of malignant melanoma is rapidly...
US20130143747 METHODS OF DETECTING CANCER  
Methods and compositions involving molecular markers for the detection and characterization of cancer in a patient are provided.
US20120021927 Methods for Determining a Prognosis for Survival for a Patient with Breast Cancer  
A method for determining a prognosis for survival for a patient with breast cancer is described. Also described is method for monitoring the effectiveness of a course of treatment for a patient...
US20110183858 GRADING OF BREAST CANCER  
Methods and compositions for the identification of breast cancer grade signatures are provided. The signature profiles are identified based upon multiple sampling of reference breast tissue...
US20110257021 USE OF THE MST PROTEIN FOR THE TREATMENT OF A THROMBOEMBOLIC DISORDER  
The present invention refers to the use of the Mst protein or a nucleotide sequence coding for the Mst protein for the treatment of a thromboembolic disorder and to a method of screening a...
US20110118131 METHODS AND MATERIALS FOR TARGETED MUTAGENESIS  
The present disclosure relates to methods and materials for mutagenesis, including for the generation of novel or improved proteins and libraries or arrays of mutant proteins or nucleic acids...
US20150087728 COMPOSITIONS, METHODS AND KITS FOR DIAGNOSIS OF LUNG CANCER  
Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung...
US20110319289 MOLECULAR-BASED METHOD OF CANCER DIAGNOSIS AND PROGNOSIS  
A gene profiling signature for diagnosis and prognosis of cancer patients is disclosed herein. In one embodiment, the gene signature includes 32 or 79 cancer survival factor-associated genes....
US20130035389 METHODS FOR TREATING MYELODYSPLASTIC SYNDROME WITH EZATIOSTAT  
This invention relates to methods, assays, devices and systems for identifying patients having a myelodysplastic syndrome for treatment with ezatiostat or a salt thereof, or evaluating the...
US20110059851 SHOC2 Mutations Causing Noonan-Like Syndrome With Loose Anagen Hair  
The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is...
US20120135950 ANTIVIRAL TREATMENT OF LYMPHOMA AND CANCER  
Compositions and methods to treat lymphoma and cancer are disclosed. In particular, the method teaches treatment of lymphoma and cancer using anti-HERV-K(HML-2) therapies. Further taught are...
US20120329662 HYPOXIA TUMOUR MARKERS  
The present invention relates to a method for assessing a hypoxia phenotype of a tumour of a subject in which the gene expression of between 3 and 50 hypoxia-related genes of a sample obtained...
US20120058916 DIAGNOSTIC METHODS FOR LIVER DISORDERS  
The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment...
US20150080257 METHOD FOR EVALUATING URATE TRANSPORT-RELATED DISEASE FACTOR AND INFLAMMATION-RELATED DISEASE FACTOR  
A method and evaluation kit are provided, in which a high-capacity urate transporter is identified to assist in the early treatment and prevention of urate transport-related disease and...
US20150133323 METHOD FOR CHARACTERIZING CIRCULATING TUMOR CELLS, AND USE THEREOF IN DIAGNOSIS  
Disclosed is a method for characterization, in a biological sample, of circulating tumour cells (CTCs) bearing at least one marker characteristic of the tumorous nature of the cell, the marker...
US20120278909 COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE  
In alternative embodiments, the invention provides nucleic acid sequences that are genetic polymorphic variations of the human TMEM216 gene, and TMEM216 polypeptide encoded by these variant...
US20110144076 PRETERM DELIVERY DIAGNOSTIC ASSAY  
The present invention in one aspect relates generally to the identification, provision and use of a plurality of biomarkers to provide risk assessment of a woman for preterm delivery, and products...
US20100331833 IN-VITRO DEVICE MONITORING DURING MINIMALLY INVASIVE ABLATION THERAPY  
A method and apparatus for monitoring and controlling interventional therapy is described, where the interventional therapy results in the destruction of tissue and the release of chemical...
US20110288151 METHODS OF CHARACTERIZING BREAST CANCER AND IDENTIFYING TREATMENTS FOR SAME  
This application describes antibodies to P-Rex 1, and methods of detecting breast cancer, and methods of treatments for the same.
US20140243219 METHODS AND SIGNATURES FOR OROPHARYNGEAL CANCER PROGNOSIS  
Methods for determining the prognosis of a subject with oropharyngeal squamous cell carcinoma are described, as well as miRNAs and panels of prognostic miRNAs that are used in the methods.
US20120052066 MARKERS AND METHODS FOR ASSESSING AND TREATING LUPUS PATIENTS SUSCEPTIBLE TO PHOTOPROVOCATION  
A method for predicting or detecting susceptibility to lupus of an individual subjected to photoprovocation obtains biological samples from the individual before and after exposure to...
US20140171332 SYSTEM FOR THE EFFICIENT DISCOVERY OF NEW THERAPEUTIC DRUGS  
The invention provides for carrying out 3-dimensional similarity searching by comparing a probe molecule to each member of a 3-dimensional database. The probe molecule is overlapped with each...