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US20110105360 PAPER-BASED CELLULAR ARRAYS  
Three-dimensional cellular arrays, methods of making three-dimensional cellular arrays, and methods of identifying agents using the arrays are disclosed.
US20110136692 PROTEIN MICROARRAYS FOR MASS SPECTROMETRY AND METHODS OF USE THEREFOR  
The present invention relates to the use of mass spectrometry to analyze arrays. The present invention provides methods for characterizing solutions comprising one or more proteins using arrays...
US20120172243 SYSTEMS AND METHODS FOR EXPRESSION-BASED CLASSIFICATION OF THYROID TISSUE  
A system for classifying thyroid nodule tissue as malignant or benign is provided that is based on the identification of sets of gene transcripts, which are characterized in that changes in...
US20150204890 MICROARRAYS OF G PROTEIN COUPLED RECEPTORS  
Microarrays encompassing GPCRs, methods of making such microarrays, and methods of using such microarrays are described.
US20100304994 Oligonucleotide Paints  
Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided.
US20140303009 Compositions, Methods, and Kits for Identifying Candidate Molecules from Encoded Chemical Libraries  
The subject matter relates to relates to a one-bead-one-sequence composition, a library of tagged chemicals comprising a plurality of one-bead-one-sequence compositions, a method for identifying a...
US20120021940 Compositions, Methods, and Kits for Identifying Candidate Molecules from Encoded Chemical Libraries  
The subject matter relates to relates to a one-bead-one-sequence composition, a library of tagged chemicals comprising a plurality of one-bead-one-sequence compositions, a method for identifying a...
US20150204876 PROTEIN MICROARRAY FOR CHARACTERIZING THE SPECIFICITY OF THE MONOCLONAL IMMUNOGLOBULINS OF MGUS OR MYELOMA PATIENTS  
The present invention concerns materials and methods for characterizing monoclonal immunoglobulin specificity of a Monoclonal Gammopathy of Undetermined Significance (MGUS) or Myeloma patients...
US20130040862 MULTI-PILLAR STRUCTURE FOR MOLECULAR ANALYSIS  
A multi-pillar structure for molecular analysis is provided. The structure comprises at least two nanopoles, each nanopole attached at one end to a substrate and freely movable along its length....
US20140329721 ASSAY PANELS  
Described herein are kits and components thereof used for a multiplexed analysis of a set of cytokines.
US20150197799 POLYNUCLEOTIDE MODIFICATION ON SOLID SUPPORT  
The present disclosure relates to the field of molecular biology and more specifically to methods for capturing and amplifying target polynucleotides on a solid surface.
US20110046005 METHOD AND NUCLEIC ACIDS FOR THE ANALYSIS OF COLON CELL PROLIFERATIVE DISORDERS  
Provided are methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders by analysis of one or more of the genes Versican, TPEF,...
US20110275544 MICROFLUIDIC INTEGRATION WITH NANOSENSOR PLATFORM  
The present invention describes microfluidics being employed to achieve multiplex surface functionalization of nanosensor chips by selectively delivering probe molecules to individual nanosensors...
US20110111978 DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES  
The present invention provides diverse chemical libraries bound to small particle with paramagnetic properties. Typically, the chemical structures comprise a plurality of different chemical...
US20110301062 RELIABLE FLUORESCENCE CORRECTION METHOD FOR TWO-COLOR MEASUREMENT FLUORESCENCE SYSTEM  
Methods and devices use in two-color measurement systems. The methods and devices include methods of making corrections, methods of calculating correction factors, fluorescence scanners, and...
US20130065788 ASSAY MODULES HAVING ASSAY REAGENTS AND METHODS OF MAKING AND USING SAME  
We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays....
US20120190578 Plasma Complement Components as Expression Markers for Age-Related Macular Degeneration and Related Phenotypes  
The present invention is directed to systems and method for predicting risk of AMD or a susceptibility to AMD in a patient by detecting elevated serum or plasma levels of C3, CFB or CFH and other...
US20130053258 COMBINATORIAL LIBRARY, A METHOD FOR PREPARATION OF THAT COMBINATORIAL LIBRARY, A METHOD FOR SEQUENCE IDENTIFICATION, A METHOD FOR SEQUENCING THE ELEMENTS OF COMBINATORIAL LIBRARIES OF OLIGONUCLEOTIDES AND/OR OLIGONUCLEOTIDE ANALOGUES, THE USE OF A LINKER TO GENERATE COMBINATORIAL LIBRARIES AND A SEQUENCE IDENTIFICATION SET  
The invention provides a combinatorial library, a method for preparation of that combinatorial library, a method for sequence identification, a method for sequencing the elements of combinatorial...
US20140038847 SCREENING AND CULTURING DEVICE AND METHODS FOR THE USE THEREOF  
In accordance with one aspect of the present invention, screening and culturing devices have been developed which are useful for the identification of media which support cell viability, growth...
US20130345081 HUMAN FACTOR XIII AS A NORMALIZATION CONTROL FOR IMMUNOASSAYS  
The present disclosure provides compositions and methods that are useful for normalizing the amount of signal detected in an assay, such as an immunoassay. The compositions and methods are useful...
US20110306521 SEPARATION OF PYROPHOSPHATE RELEASE AND PYROPHOSPHATE DETECTION  
The present technology relates to methods and systems for detection of pyrophosphate. As such, disclosed herein are methods and systems that permit improved pyrophosphate detection. Also disclosed...
US20150119274 Microplates with Enhanced Immobilisation Capabilities Controlled by Magnetic Field  
The present invention describes microplates with arrays of wells containing magnetic inserts in the form of disks, cylinders or otherwise shaped materials with apertures in the centre for optical...
US20140235510 MICROFLUIDIC INTERFACE FOR HIGHLY PARALLEL ADDRESSING OF SENSING ARRAYS  
Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or...
US20130225452 Method of Preparing a Nucleic Acid Library  
A method of preparing a nucleic acid library in droplets in contact with oil, including: (a) blunt-ending nucleic acid fragments in a droplet in the oil to yield blunt-ended nucleic acid...
US20110092384 COMPOSITIONS AND METHODS FOR PRODUCING CODED PEPTOID LIBRARIES  
Embodiments of the invention are directed to a one-bead-two-compound method for the creation of encoded cyclic peptoid libraries. This scheme is useful for the creation of cyclic peptoid...
US20130017974 METHODS AND COMPOSITIONS RELATING TO MULTIPLEX GENOMIC GAIN AND LOSS ASSAYS  
Compositions and methods are provided for detecting genomic DNA gain and loss. Embodiments of inventive compositions and methods include composite nucleic acid probes which specifically hybridize...
US20120190564 IDENTIFICATION OF PROTEIN BINDING SITES  
The disclosure relates to the field of molecular recognition or detection of discontinuous or conformational binding sites or epitopes corresponding to a binding molecule, in particular, in...
US20140018256 METHOD OF DIAGNOSING AUTISM SPECTRUM DISORDER  
The present invention provides a method for diagnosing an autism spectrum disorder (ASD), or predisposition to develop an ASD, in a subject, which comprises the step of investigating a set of...
US20130338014 Calibration Standards For Digital Histocytometry  
An analytical reference for digital histochemistry is constituted of an on-slide standard used to calibrate biomarker expression in biopsy material and tissue sections. The standard consists of...
US20140342935 BASE FOR USE IN AMPLIFICATION OF NUCLEIC ACID AND METHOD FOR AMPLIFYING NUCLEIC ACID  
The present invention is to provide a base for use in the amplification of a nucleic acid, which makes it possible to accurately and effectively amplify and detect a plurality of target nucleic...
US20150094238 Reagent Bead Inserter  
A system for inserting reagent or macrobeads into bores of a sample plate is disclosed comprising an insertion device arranged to retain one or more reagent or macrobeads by means of a vacuum...
US20150218620 METHODS TO CAPTURE AND/OR REMOVE HIGHLY ABUNDANT RNAS FROM A HETEROGENOUS RNA SAMPLE  
The invention is directed to a method of using DNA oligonucleotides as baits to capture and selectively remove highly abundant RNAs from a heterogeneous RNA sample for improved enrichment of other...
US20100285992 MICRO-PATTERNED PLATE COMPOSED OF AN ARRAY OF RELEASABLE ELEMENTS SURROUNDED WITH SOLID OR GEL WALLS  
A micro-patterned plate composed of an array of releasable elements surrounded by a gel or solid wall and methods of manufacture of the micropatterned plate. The surface properties of walls can be...
US20130035261 USE OF N-ALKYL IMIDAZOLE FOR SULFURIZATION OF OLIGONUCLEOTIDES WITH AN ACETYL DISULFIDE  
A method and compositions for sulfurizing at least one phosphite or thiophosphite linkage in an oligonucleotide. The addition of N-alkyl imidazole to the acetyldisulfide sulfurization solution...
US20090136583 Sol-Gel phase-reversible hydrogel templates and uses thereof  
Discrete microstructures of predefined size and shape are prepared using sol-gel phase-reversible hydrogel templates. An aqueous solution of hydrogel-forming material is covered onto a...
US20110136691 GOLD-SILVER ALLOY NANOPARTICLE CHIP, METHOD OF FABRICATING THE SAME AND METHOD OF DETECTING MICROORGANISMS USING THE SAME  
Provided are a gold-silver alloy nanoparticle chip, a method of fabricating the same and a method of detecting microorganisms using the same. The gold-silver alloy nanoparticle chip includes a...
US20120040872 PREPARING CARBOHYDRATE MICROARRAYS AND CONJUGATED NANOPARTICLES  
The present invention is directed to carbohydrate microarray and conjugated nanoparticles methods of making the same.
US20120053091 METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES  
The present invention features a number of methods for identifying one or more compounds that bind to a biological target. The methods include synthesizing a library of compounds, wherein the...
US20110136687 METHOD FOR DETERMINING THE DEGREE OF METHYLATION OF DEFINED CYTOSINES IN GENOMIC DNA IN THE SEQUENCE CONTEXT OF 5'-CpG-3'  
A method is described for the detection of the degree of methylation of a specific cytosine in the sequence context 5′-CpG-3′ of a genomic DNA sample. In the first step, the genomic DNA is...
US20120309647 PATTERNING AND CELLULAR CO-CULTURE  
Cell co-culturing methods and arrays providing versatility and high resolution. A method comprising: providing at least one substrate; providing at least one first tip with at least one first...
US20140323351 SINGLE CELL ARRAY MICROCHIP AND FABRICATION, ELECTRICAL MEASUREMENT AND ELECTROPORATION METHOD THEREOF  
The present invention relates to single cell array micro-chips and fabrication, electrical measurement and electroporation method thereof. The single cell array microchip comprises a substrate...
US20150253317 LABEL-FREE DETECTION OF RENAL CANCER  
Natural and/or synthetic antibodies for specific proteins are adhered to nanoparticles. The nanoparticles are adhered to a substrate and the substrate is exposed to a sample that may contain the...
US20130184170 OLIGONUCLEOTIDE AMPLIFICATION PRIMERS FOR TARGETING ONCOGENIC HPV  
The present invention relates generally to the field of diagnostic and detection assays. More particularly, the present invention provides methods and reagents including biochips for detecting the...
US20120108451 METHODS AND APPARATUS FOR NANOPARTICLE-ASSISTED NUCLEIC ACID HYBRIDIZATION AND MICROARRAY ANALYSIS  
The invention provides nucleic acid hybridization methods for detecting target nucleic acid sequences wherein complexes comprising nanoparticles non-covalently associated with single-stranded...
US20120322681 Methods for Preparative In Vitro Cloning  
Methods and devices relate to the isolation of nucleic acids of interest from within a population of nucleic acids such as libraries of nucleic acid sequences.
US20130178397 USING POPULATIONS OF BEADS FOR THE FABRICATION OF ARRAYS ON SURFACES  
The present invention provides a method of creating an array of features. The method can include steps of (a) providing a plurality of beads, wherein each bead in the plurality of beads includes...
US20110046018 SERS-BASED, SINGLE STEP, REAL-TIME DETECTION OF PROTEIN KINASE AND/OR PHOSPHATASE ACTIVITY  
This invention provides novel compositions and methods for the detection, and/or quantification, of the presence and/or activity of one or more kinases and/or phosphatases. In certain embodiments...
US20150168391 METHOD FOR TREATING A POROUS MEMBRANE AND USES THEREOF  
The present invention relates to a method for treating a porous membrane, said method comprising contacting said porous membrane with at least one alcohol to reduce the pore size of said porous...
US20150182932 COMBINATORIC ENCODING METHODS FOR MICROARRAYS  
A microarray for detecting a presence of one or more target analytes in a sample includes an array of particles having one or more binding sites thereon for binding with the one or more target...
US20110045994 PARTICLE CAPTURE DEVICES AND METHODS OF USE THEREOF  
The present invention provides a device and methods of use thereof in microscale particle capturing and particle pairing. This invention provides particle patterning device, which mechanically...

Matches 1 - 50 out of 362 1 2 3 4 5 6 7 8 >