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US20100298160 |
METHOD AND TOOLS FOR PROGNOSIS OF CANCER IN ER-PATIENTS
A gene or protein set includes at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41,...
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US20130130939 |
PORTABLE PHOTONIC SENSOR SYSTEM AS AN EARLY DETECTION TOOL FOR OVARIAN CANCER
A guided mode resonance (GMR) sensor that can be used to simultaneously detect an array of analytes. It provides a diagnostic system that can rapidly detect an array of biomarker proteins in...
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US20120088685 |
DIAGNOSIS OF NEUROPSYCHIATRIC AND BEHAVIOURAL DISORDERS
This invention provides a method of identifying GAS infection as the cause of a neuropsychiatric or behavioural disorder in a patient, or of identifying a patient at risk of developing a...
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US20120276145 |
EXTRACELLULAR MATRIX PROTEINS FROM HAEMOPHILUS INFLUENZAE BIOFILMS: TARGETS FOR THERAPEUTIC OR DIAGNOSTIC USE
A method of identifying a biofilm that includes non-typeable Haemophilus influenza (NTHi) including a step of screening a sample for the presence of one or more biofilm-specific proteins that are...
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US20120238478 |
PROTEIN MARKERS FOR THE DIAGNOSIS AND PROGNOSIS OF OVARIAN AND BREAST CANCER
Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of...
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US20120046182 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
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US20130122027 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
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US20110190149 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
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US20120231969 |
PROTEIN ARRAYS AND USES THEREOF
Illustrative embodiments herein disclosed relate to protein arrays, methods for making the arrays and methods for using them, among others. In some embodiments known proteins representing at least...
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US20120028835 |
SECERNIN-1 AS A MARKER FOR CANCER
Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a...
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US20120214710 |
METHOD OF PREDICTING RESPONSE TO THALIDOMIDE IN MULTIPLE MYELOMA PATIENTS
A method of predicting response to thalidomide, or thalidomide analogs, in an individual with cancer, especially cancers for which thalidomide has been implicated as a treatment, such as Multiple...
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US20130058863 |
4-Protein Biomarker Panel for the Diagnosis of Lymphoma from Biospecimen
A panel of lymphoma related biomarkers are provided. The panel allows the identification of a subject at risk for a lymphoma. Further provided are methods of optimizing therapeutic efficacy...
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US20110257042 |
Debulking Catheters And Methods
A debulking catheter comprising a tissue debulking assembly for removing a continuous strand of material from a body lumen. Catheters of the present invention generally include a catheter body...
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US20120178640 |
Nanotube Array for Optical Detection of Protein-Protein Interactions
A composition can include a nanostructure, and a linker associated with the nanostructure, wherein the linker is configured to interact with a capture protein. The nanostructure can include a...
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US20110065609 |
Methods and Kits for the Diagnosis of Rheumatoid Arthritis
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins...
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US20130090256 |
BIOMARKERS FOR EARLY DETECTION OF OVARIAN CANCER
Biomarker proteins that can be used in the diagnosis of early-stage ovarian cancer (OC) are described. The biomarker panels not only permit the distinction of patients with ovarian neoplasia...
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US20110306507 |
METHOD AND TOOLS FOR PROGNOSIS OF CANCER IN HER2+PARTIENTS
A gene or protein set includes at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, and possibly 40, 45, 50,...
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US20130079249 |
GLYCOSYLATION ASSAY, GLYCOANALYSIS ARRAY AND AN ASSAY SYSTEM
An improved glycosylation assay, glycoanalysis array and an assay system for performing glycosylation assays glycoanalysis array.
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US20120289429 |
BIOCHIP COMPRISING MULTIPLE MICROCHANNELS
A biochip includes a plurality of microchannels; and a plurality of probes disposed in an inner wall of each of the plurality of microchannels forming a one-dimensional array. The one-dimensional...
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US20110136692 |
PROTEIN MICROARRAYS FOR MASS SPECTROMETRY AND METHODS OF USE THEREFOR
The present invention relates to the use of mass spectrometry to analyze arrays. The present invention provides methods for characterizing solutions comprising one or more proteins using arrays and...
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US20110257035 |
IDENTIFICATION OF SIGNATURE GENES ASSOCIATED WITH HEPATOCELLULAR CARCINOMA
The present invention relates to, for example, (1) a novel method for identification of clinically useful serum and/or tumor biomarkers and expression signatures that can be used for detection,...
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US20110301057 |
IN SITU ORIENTED IMMOBILIZATION OF PROTEINS ON A SUPPORT
The present invention relates to a method of directing in situ oriented immobilization of a protein on a support. This method involves providing a support and contacting the support with a...
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US20120184560 |
MOLECULAR DIAGNOSTIC METHODS FOR PREDICTING BRAIN METASTASIS OF BREAST CANCER
Disclosed are molecular diagnostic compositions and methods for predicting brain metastasis of breast cancer, as well as methods for drug repositioning to identify existing and new therapeutics for...
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US20120087862 |
ORGAN-SPECIFIC PROTEINS AND METHODS OF THEIR USE
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific...
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US20110190168 |
APOPTOSIS MODULATOR BCL-B AND METHODS FOR MAKING AND USING SAME
A novel human member of the Bcl-2 family Bcl-B has been identified, which is Closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is Widely expressed in adult human...
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US20130045873 |
METHODS FOR IDENTIFYING AND USING ORGAN-SPECIFIC PROTEINS IN BLOOD
The present invention relates generally to methods for identifying organ-specific secreted proteins and for identifying organ-specific molecular blood fingerprints therefrom. As such, the present...
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US20120157335 |
Flap Endonuclease-1 As A Marker For Cancer
Methods aiding in the assessment of cancer comprising use of the Flap endonuclease-1 protein (=FEN1) as a universal marker of different cancer types are provided. In particular, methods for...
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US20120328594 |
PROTEIN AND LIPID BIOMARKERS PROVIDING CONSISTENT IMPROVEMENT TO THE PREDICTION OF TYPE 2 DIABETES
The invention relates to biomarkers associated with Diabetes, including protein and lipid metabolite biomarkers, methods of using the biomarkers to determine the risk that an individual will...
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US20130137595 |
BIOMARKERS FOR LYMPHOMA
A biomarker, method, test kit, and diagnostic system for detecting the presence of lymphoma in a person are disclosed. The lymphoma may be Hodgkin's lymphoma or non-Hodgkin's lymphoma. The person...
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US20120190565 |
Method Of Diagnosis Or Prognosis Of A Neoplasm Comprising Determining The Level Of Expression Of A Protein In Stromal Cells Adjacent To The Neoplasm
The invention provides diagnostic and therapeutic methods for neoplastic disease patients with neoplasms of, for example, the breast, skin, kidney, lung, pancreas, rectum and colon, prostate,...
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US20120302464 |
METHODS FOR PRODUCING RECOMBINANT PROTEINS
Methods for producing recombinant cell populations are disclosed. The disclosed methods may be used to produce therapeutic polyclonal proteins.
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US20120021927 |
Methods for Determining a Prognosis for Survival for a Patient with Breast Cancer
A method for determining a prognosis for survival for a patient with breast cancer is described. Also described is method for monitoring the effectiveness of a course of treatment for a patient...
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US20120122726 |
MARKERS FOR ENDOMETRIAL CANCER
The invention relates to the surprising finding that biomarkers corresponding to ACAA1, AP1M2, CGN, DDR1, EPS8L2, FASTKD1, GMIP, IKBKE, P2RX4, P4HB, PHKG2, PPFIBP2, PPP1 R16A, RASSF7, RNF183,...
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US20110118131 |
METHODS AND MATERIALS FOR TARGETED MUTAGENESIS
The present disclosure relates to methods and materials for mutagenesis, including for the generation of novel or improved proteins and libraries or arrays of mutant proteins or nucleic acids...
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US20120258877 |
IDENTIFICATION OF CANCER BIOMARKERS AND PHOSPHORYLATED PROTEINS
Methods are provided for identifying proteins that are differentially expressed in disease state and normal cells. Stable isotope labeling of cells in culture allows for the identification of a...
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US20120065106 |
Methods and Compositions for Enhanced Protein Expression and Purification
Methods for enhancing expression levels, secretion, and purification of heterologous fusion proteins in a host cell are disclosed.
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US20130121999 |
BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER
The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from breast cancer, in particular locally advanced, recurrent or...
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US20110319289 |
MOLECULAR-BASED METHOD OF CANCER DIAGNOSIS AND PROGNOSIS
A gene profiling signature for diagnosis and prognosis of cancer patients is disclosed herein. In one embodiment, the gene signature includes 32 or 79 cancer survival factor-associated genes. Thus,...
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US20110177974 |
NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS
The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree...
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US20120149596 |
METHODS FOR ASSESSING ATHEROGENESIS BY DETERMINING OXIDIZED PHOSPHOLIPID TO APOLIPOPROTEIN B RATIOS
The present invention relates to the analysis of oxidized phospholipids (OxPL) on apolipoprotein B-100 in patients at high risk or with documented coronary artery disease (CAD) or acute coronary...
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US20120321615 |
Assay for Metastatic Colorectal Cancer
Disclosed herein is a method for predicting the prognosis, the likelihood of metastasis in, or the desirability of administering an aggressive therapy to, a subject with colorectal cancer,...
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US20120264639 |
METHODS AND COMPOSITIONS FOR PREDICTING SURVIVAL IN SUBJECTS WITH CANCER
Methods for generating a prognostic signature for a subject with pancreatic ductal adenocarcinoma (PDAC) are disclosed. In some embodiments, the methods include determining expression levels for...
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US20120283114 |
NEW DIAGNOSTIC TOOLS FOR ALZHEIMER DISEASE
The present invention relates to development, validation and application of new sets of biomarkers for diagnosis of Alzheimer's disease (AD) and related disorders including early diagnosis of MCI...
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US20130085075 |
DIAGNOSTIC METHODS FOR LIVER DISORDERS
The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment...
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US20110136675 |
IDENTIFICATION AND CHARACTERIZATION OF PROTEINS USING NEW DATABASE SEARCH MODES
A method of selecting a set of candidate polypeptides for a sample polypeptide that includes a first refining of a collection of candidate polypeptides from differences in mass of fragments of the...
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US20130130928 |
METHODS FOR PREDICTING OR MONITORING WHETHER A PATIENT AFFECTED BY A CANCER IS RESPONSIVE TO A TREATMENT WITH A MOLECULE OF THE TAXOID FAMILY
The present invention concerns in vitro methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family based on a...
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US20100292096 |
STRAIN AND SPECIES-SPECIFIC BORRELIA PROTEIN ARRAY
Methods of assessing a sample for the presence of antibodies to certain proteins of Borrelia burgdorferi, are described, as are methods of diagnosing Lyme disease. Microarrays of proteins of...
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US20110065594 |
Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample...
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US20130045884 |
MEANS AND METHODS FOR DIAGNOSING PANCREATIC CANCER
The present invention pertains to the field of cancer diagnosis. Specifically, it relates to a method for diagnosing pancreas cancer in a subject comprising the steps of determining in a sample of...
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US20100304412 |
METHODS FOR DETERMINING THE RISK OF PRENATAL COMPLICATIONS
The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain...
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