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US20140255301 METHODS FOR DETECTING NEURODEGENERATIVE DISEASES OR DISORDERS  
Methods of identifying, diagnosing, and prognosing a neurodegenerative disease, or disorder, are provided. Also provided are methods for determining whether a neuron is at risk or is undergoing...
US20130017971 Multivariate Diagnostic Assays and Methods for Using Same  
The application describes compositions and methods for detecting the relative expressions of a plurality of target nucleic acid molecules in one assay. The compositions comprise a plurality of...
US20120258889 siRNA Targeting Kinase Insert Domain Receptor (KDR)  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20110009286 MOLECULAR IN VITRO DIAGNOSIS OF BREAST CANCER  
The invention relates to the use of a multiplicity of polynucleotide probe sets, the multiplicity of polynucleotide probe sets consisting in a combination of pools of polynucleotide probe sets,...
US20150148432 ASSESSING SUSCEPTIBILITY TO VASCULAR DISORDERS  
The invention provides methods and reagents for determination of risk and treatment of a vascular disorder such as abdominal aortic aneurysm (AAA) by detecting presence of gene polymorphisms...
US20150167092 FRET-BASED ANALYTES DETECTION AND RELATED METHODS AND SYSTEMS  
FRET-based analytes detection and related methods and systems are described where a pair of FRET labeled primers and/or oligonucleotides are used that are specific for target sequences located at...
US20110269632 Detection of Cancer through Breath Comprising a Sensor Array Comprising Capped Conductive Nanoparticles  
Sensor array for detecting biomarkers for cancer in breath samples. The sensor array is based on 2D films or 3D assemblies of conductive nanoparticles capped with an organic coating wherein the...
US20130316922 QUANTITATION AND PROFILING OF VAGINAL MICROFLORA  
Disclosed are methods of quantifying microflora in vaginal samples. Quantitative assessment of vaginal microflora by real-time PCR to create a profiling of Lactobacillus species, Gardnerella...
US20150252408 METHODS AND KITS USEFUL IN THE DIFFERENTIATION OF BURKHOLDERIA SPECIES  
The invention pertains to sequences, methods, and kits useful in the identification of and differentiation between Burkholderia pseudomallei and Burkholderia mallei. The methods generally involve...
US20110105363 siRNA targeting TNFa  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20130065772 PROGNOSTIC MOLECULAR SIGNATURE OF SARCOMAS, AND USES THEREOF  
Described herein are methods and compositions that can be used for diagnosis and treatment of soft tissue sarcoma cancer phenotypes and soft tissue sarcoma cancer-associated diseases. Also...
US20130261025 METHODS FOR DETECTING INFLAMMATORY BOWEL DISEASE  
The present invention provides for a method of detecting the presence of inflammatory bowel disease in gastrointestinal tissues or cells of a mammal by detecting increased expression of LY6 genes...
US20120264631 Targets For Use In Diagnosis, Prognosis And Therapy Of Cancer  
Provided herein are targets that can be used for the diagnosis, prognosis and therapy of a variety of cancers.
US20130288909 miRNA DETECTION OF PANCREATIC CANCER  
Methods for the diagnosis and/or monitoring of pancreatic cancer by detection of micro-RNAs (miRNA) are provided. In certain embodiments, detection of miR-21, miR-210, miR-155, and/or miR-196a in...
US20140309129 Encoded Nanopore Sensor for Multiplex Nucleic Acids Detection  
The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity...
US20120157337 miRNA FINGERPRINT IN THE DIAGNOSIS OF MULTIPLE SCLEROSIS  
The present invention provides novel methods for diagnosing diseases based on the determination of specific miR-NAs that have altered expression levels in disease states compared to healthy controls.
US20150203900 Methods of Diagnosing Infectious Disease Pathogens and Their Drug Sensitivity  
The specification relates generally to methods of detecting, diagnosing, and/or identifying pathogens, e.g., infectious disease pathogens and determining their drug sensitivity and appropriate...
US20130079245 Biomarkers for Ulcerative Colitis and Crohn's Disease  
The present invention provides compositions and their use in diagnosing ulcerative colitis, Crohn's Disease, and inflammatory bowel disease.
US20110301051 Biomarkers for Ulcerative Colitis and Crohn's Disease  
The present invention provides compositions and their use in diagnosing ulcerative colitis, Crohn's Disease, and inflammatory bowel disease.
US20150259732 NUCLEIC ACID ANALYSIS KIT AND NUCLEIC ACID ANALYSIS METHOD  
A number of samples provided for analysis are identified correctly by making use of smaller kinds of nucleic acids. Provided is a nucleic acid analysis kit having a plurality of supports that...
US20130331281 MOLECULAR MARKERS FOR PROGNOSTICALLY PREDICTING PROSTATE CANCER, METHOD AND KIT THEREOF  
The present application provides a method for predicting clinical prognosis for a human subject diagnosed with prostate cancer, comprising: detecting an expression level of a marker gene selected...
US20130130931 BIOMARKER FOR THE DIAGNOSIS, PROGNOSIS AND MONITORING OF CANCER  
The present invention provides a new biomarker for the diagnosis, prognosis and monitoring of cancer, preferably breast and colon cancer, the PIK3R2 gene or any of its expression products; since...
US20110092379 GENOTYPING METHOD AND MEANS THEREOF FOR USE IN TRACEABILITY SCHEMES  
The invention discloses means and methods for genotyping an individual head of cattle. Individual's DNA is genotyped utilising the herein defined PCR SNaP-shot protocol. The protocol comprises two...
US20140080731 THYROID CANCER DIAGNOSTICS  
Disclosed herein, in certain instances, are methods for the diagnosis, prognosis and determination of cancer progression of a cancer in a subject. Further disclosed herein, in certain instances,...
US20140087961 GENETIC VARIANTS USEFUL FOR RISK ASSESSMENT OF THYROID CANCER  
The invention discloses genetic variants that have been determined to be susceptibility variants of thyroid cancer. Methods of disease management, including methods of determining susceptibility...
US20120309645 miRNA IN THE DIAGNOSIS OF OVARIAN CANCER  
The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g....
US20110081367 INFLUENZA SEQUENCES  
We provide a nucleic acid sequence as shown in Table D1 or Table D2, or a variant, homologue, derivative or fragment thereof. A combination of two or more sequences is also provided. The nucleic...
US20150252412 HIGH-DEFINITION DNA IN SITU HYBRIDIZATION (HD-FISH) COMPOSITIONS AND METHODS  
The invention provides methods and compositions relating to high definition fluorescence DNA in situ hybridization (HD-FISH). The probes generated using the methods of the invention demonstrate...
US20130317006 Use of polymorphisms for identifying individuals at risk of developing autism  
The present invention relates to nucleic-acid based diagnostics and the use of such diagnostics for the diagnosis of developmental disorders. Novel methods of assessing individuals for the risk of...
US20130045886 Methods For Diagnosing Feline Coronavirus Infections  
Provided is a method for determining whether a feline is infected with pathogenic Feline Infectious Peritonitis Virus (FIPV) or Feline Enteric Infection Virus (FECV). The method involves...
US20110059856 IN VITRO DIAGNOSTIC METHOD FOR THE DIAGNOSIS OF SOMATIC AND OVARIAN CANCERS  
Method of using one element chosen among a nucleic acid molecule, a fragment of the nucleic acid molecule and a variant of the nucleic acid molecule for the in vitro or ex vivo diagnosis of any...
US20120065081 NUCLEIC ACID CONSTRUCTS AND METHODS OF USE  
The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to provide validated sequences or sets of...
US20110152113 GENOMIC FINGERPRINT OF BREAST CANCER  
The present invention relates to in vitro methods for determining the prognosis of a subject diagnosed with breast cancer developing metastasis or for selecting suitable treatment for said...
US20140031261 OLIGONUCLEOTIDE REPLACEMENT FOR DI-TAGGED AND DIRECTIONAL LIBRARIES  
Transposomes and oligonucleotide replacement methods to make DNA libraries that have distinct 5′ and 3′ tags, and to make directional libraries that are enriched for a desired strand.
US20130065788 ASSAY MODULES HAVING ASSAY REAGENTS AND METHODS OF MAKING AND USING SAME  
We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays....
US20120264635 DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH PROGNOSIS OF NON SMALL CELL LUNG CANCER  
The methods and compositions described herein address the need for a diagnostic method that can be provided to patients with early stage lung cancer, especially non-small cell lung cancer (NSCLC),...
US20120157336 miRNA FINGERPRINT IN THE DIAGNOSIS OF DISEASES  
The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g....
US20130252836 DIAGNOSTIC TEST FOR CARDIOMYOPATHY  
Methods and compositions relating to diagnosing and treating cardiomyopathy and particularly relating to methods and compositions for diagnosing and treating arrhythmogenic right ventricular...
US20130012406 METHODS AND KITS FOR MULTIPLEX AMPLIFICATION OF SHORT TANDEM REPEAT LOCI  
Methods and materials are disclosed for use in simultaneously amplifying at least 11 specific STR loci of genomic DNA in a single multiplex reaction, as are methods and materials for use in the...
US20140094390 siRNA Targeting TIE-2  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20110077173 siRNA targeting TIE-2  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20130338018 PRIMERS, SEQUENCES AND RECOMBINANT PROBES FOR IDENTIFICATION OF MYCOBACTERIUM SPECIES  
The subject invention pertains to an assay and a method for diagnosing, identifying and/or differentiating microorganisms, and in particular bacteria such as Mycobacterium spp. within biological...
US20130280705 METHODS AND COMPOSITIONS FOR ASSESSMENT OF PULMONARY FUNCTION AND DISORDERS  
The present invention provides methods for the assessment of risk of developing lung cancer in smokers and non-smokers using analysis of genetic polymorphisms. The present invention also relates...
US20120165214 METHODS AND COMPOSITIONS FOR ASSESSMENT OF PULMONARY FUNCTION AND DISORDERS  
The present invention provides methods for the assessment of risk of developing lung cancer in smokers and non-smokers using analysis of genetic polymorphisms. The present invention also relates...
US20120135889 METHODS AND COMPOSITIONS FOR IMPROVED FERTILIZATION AND EMBRYONIC SURVIVAL  
Single nucleotide polymorphic site at position 11646 of the bovine FGF2 gene is associated with improved fertilization rate and/or improved embryo survival rate, as well as improved milk...
US20140213533 METHODS TO DETECT, TREAT AND PREVENT ACUTE CELLULAR REJECTION IN KIDNEY ALLOGRAFTS  
Methods for prevention and treatment of kidney transplant rejection are described that involve determination, analysis and computation of a 3-gene molecular signature of levels of specific RNAs...
US20150057159 METHOD TO IDENTIFY ASYMPTOMATIC HIGH-RISK INDIVIDUALS WITH EARLY STAGE LUNG CANCER BY MEANS OF DETECTING miRNAs IN BIOLOGIC FLUIDS  
A diagnostic and/or prognostic model of at least 5 serum miRNAs selected among a group of 34 miRNAs that identifies subjects with early stage lung cancer, namely non-small cell lung carcinomas...
US20140256588 METHODS FOR CONDUCTING MULTIPLEXED ASSAYS  
The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of...
US20110119776 METHODS OF DIAGNOSING AND PROGNOSING LUNG CANCER  
The present invention provides methods of detecting cancer using biomarkers.
US20150071947 METHODS OF IDENTIFYING GENE ISOFORMS FOR ANTI-CANCER TREATMENTS  
Novel methods of classifying subjects as candidates for treatment with agent that inhibits or kills cancer associated mesenchymal cells, tumor initiating cancer cells, or cancer stem cells...