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US20150159225 UVEAL MELANOMA PROGNOSIS  
Methods and kits for monitoring or providing a prognosis for a subject having uveal melanoma are described. The methods include obtaining a biological sample from the subject, determining the...
US20140037620 Methods of Treating Breast Cancer with Gemcitabine Therapy  
The application describes methods for predicting overall survival in subjects with breast cancer. The application also describes for screening subjects with breast cancer to determine if the...
US20150087589 GENES AND PROTEINS ASSOCIATED WITH ANGIOGENESIS AND USES THEREOF  
Disclosed is a panel of biomarkers associated with angiogenesis, and the use of such biomarkers (genes, proteins, homologues and analogs thereof) to regulate angiogenesis. Methods for identifying...
US20130196869 MICRORNA PROFILING FOR DIAGNOSIS OF DYSPLASTIC NEVI AND MELANOMA  
Provided herein are methods for miRNA profiling for the diagnosis, prognosis, and management of melanoma and differentiation of melanoma from nevi.
US20120071346 GENE-BASED ALGORITHMIC CANCER PROGNOSIS  
The present invention is related to the methods and systems for prognosis determination in tumor samples, by measuring gene expression in a tumor sample and applying a gene-expression grade index...
US20130011393 BAD PATHWAY GENE SIGNATURE  
The invention provides materials and methods for prognosing cancer, and predicting an individual's responsiveness to cancer treatments, methods of treating cancer, and materials and methods for...
US20130178378 MULTIPLEX DIGITAL PCR  
Embodiments of the claimed subject matter are directed to the ability to further multiplex in the digital regime using combinatorial color, temporal, and intensity encoding of probe sequences for...
US20140302042 METHODS OF PREDICTING PROGNOSIS IN CANCER  
A set of biomarkers (e.g., genes and gene products) that can accurately inform about the risk of cancer progression and recurrence, as well as methods of their use are disclosed.
US20130059741 BINDING ASSAYS FOR MARKERS  
This invention provides compositions and methods for assaying the presence of a target analyte in a sample using a solid support. Embodiments of the present invention provide a solid support...
US20150132297 SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA  
The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.
US20150024972 SELECTIVE NUCLEIC ACID AMPLIFICATION FROM NUCLEIC ACID POOLS  
Provided herein are nucleic acids and methods for selectively amplifying in parallel tens of thousands of high quality oligonucleotides without common sequences. The resultant oligonucleotides can...
US20150252360 METHOD FOR SYNTHESISING TEMPLATED MOLECULES  
The invention relates to a method for synthesising templated molecules attached to the templated which directed the synthesis thereof. The method involves a template, a scaffold functional entity...
US20140005065 METHOD FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES IN PERIPHERAL BLOOD MONONUCLEAR CELLS  
Methods and compositions are provided for diagnosing lung cancer in a mammalian subject by use of three or more selected gene, e.g., a gene expression profile, from the peripheral blood...
US20140256562 miRNA-BASED UNIVERSAL SCREENING TEST (UST)  
Described are methods for early noninvasive or minimally invasive detection of pathological changes in organ systems/organs/tissues/cells by quantifying organ system-/organ-/tissue-/cells...
US20120316076 BIOMARKERS FOR THE DIAGNOSIS OF LACUNAR STROKE  
This invention provides gene expression profiles useful for diagnosing lacunar stroke and for distinguishing lacunar stroke from non-lacunar stroke.
US20110263441 COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF HEPATIC DISORDERS  
The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating hepatic disorders such as hepatocellular carcinoma and/or cirrhosis. A variety of...
US20110251086 NEUROBLASTOMA PROGNOSTIC MULTIGENE EXPRESSION SIGNATURE  
The current invention relates to new tools and methods enabling neuroblastoma patient stratification into prognostic favorable or unfavorable groups. The invention is based on the re-analysis of...
US20130072393 PANCREATIC CANCER MARKERS, AND DETECTING METHODS, KITS, BIOCHIPS THEREOF  
The present invention provides microRNAs for assessing the status of pancreatic cancer in a subject, and provides methods, kits, and biochips for detecting said microRNAs.
US20140378425 BIOMARKERS FOR DIAGNOSIS OF LUNG DISEASES AND METHODS OF USE THEREOF  
The present disclosure provides methods for diagnosis of interstitial lung diseases (ILDs). The present disclosure provides methods for differential diagnosis of idiopathic pulmonary fibrosis from...
US20110288031 IDENTIFICATION OF A NOVEL BHD GENE  
The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and methods of using the nucleic acids and proteins encoded thereby. In particular, the present...
US20140371088 MULTIPLEXABLE TAG-BASED REPORTER SYSTEM  
The present invention relates to compositions and methods for the detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to...
US20140106990 MULTIPLEX DETECTION ASSAY FOR INFLUENZA AND RSV VIRUSES  
The present invention generally relates to a molecular test of Influenza A, Influenza B, Respiratory Syncytial Virus A, and Respiratory Syncytial Virus B in order to identify patients with a viral...
US20140249042 DETECTION OF BIOAGENTS USING A SHEAR HORIZONTAL SURFACE ACOUSTIC WAVE BIOSENSOR  
Viruses and other bioagents are of high medical and biodefense concern and their detection at concentrations well below the threshold necessary to cause health hazards continues to be a challenge...
US20140148364 MULTIPLEXED ANCHOR SCANNING PARALLEL END TAG SEQUENCING  
The present invention relates to a novel method and to a kit for preparing nucleic-acid libraries, in particular for high-throughput sequencing. Said method is useful for simultaneously preparing...
US20140170139 HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION  
Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided.
US20130058924 HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION  
Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided.
US20120202872 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA AND CERVICAL CANCER  
The invention provides methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer. The methods comprise the step of determining the...
US20140274735 MULTIPLEX METHYLATION-SPECIFIC AMPLIFICATION SYSTEMS AND METHODS  
The present invention relates to systems and methods for performing multiplex amplification reactions. In particular, the present invention relates to multiplex methylation-specific amplification...
US20150044224 MATERIALS AND METHODS FOR DIFFERENTIAL TREATMENT OF CANCER  
The present invention concerns differential therapeutic treatment of cancer patients based on prognostic antigen/antibody profiles used for predicting (prognosticating) a clinical response...
US20140066334 METHOD FOR THE PRODUCTION OF READING-FRAME-CORRECT FRAGMENT LIBRARIES  
The present invention relates to reading-frame-correct fragment libraries, methods for their production, and the use of the fragment libraries for selection of functional polypeptide variants with...
US20150166988 METHODS AND COMPOSITIONS  
The invention relates to a complex comprising a phage particle, said phage particle comprising (i) a polypeptide;(ii) a nucleic acid encoding the polypeptide of (i);(iii) a connector compound...
US20120157348 Detection of nucleic acids from whole  
Methods of detecting one or more nucleic acids from whole blood or plasma are provided. The nucleic acids are captured on a solid support and detected. Compositions, kits, and systems related to...
US20150094231 Oligonucleotides and Methods for Detecting KRAS and PIK3CA Mutations  
Provided are oligonucleotides that are capable of detecting KRAS and PIK3CA mutations in both cancer patients and healthy individuals with high specificity in kPCR assays. When the...
US20140094389 COMPOSITIONS AND METHODS FOR DETECTING PREDISPOSITION TO A SUBSTANCE USE DISORDER  
The present invention provides screening kits, compositions, and diagnostic methods for determining whether a subject has a predisposition to, or likelihood of having, a substance use disorder by...
US20120108444 COMPOSITIONS AND METHODS FOR DETECTING PREDISPOSITION TO A SUBSTANCE USE DISORDER  
The present invention provides screening kits, compositions, and diagnostic methods for determining whether a subject has a predisposition to, or likelihood of having, a substance use disorder by...
US20140243433 MARKER GENES FOR PROSTATE CANCER CLASSIFICATION  
The present invention relates to a method for classifying a prostate cancer in a subject, the method comprising the steps of a) determining a gene expression level or gene expression pattern of...
US20110183864 METHOD FOR LUNG CANCER EARLY DETECTION AND PROGNOSIS  
The present invention provides method for the prognosis or detection of lung cancer, notably for early detection of lung cancer, as well as a kit and a (micro) array suitable for said method.
US20120184463 siRNA Targeting Connective Tissue Growth Factor (CTGF)  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20110039734 siRNA targeting connective tissue growth factor (CTGF)  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20120108445 VEGF AND VEGFR1 GENE EXPRESSION USEFUL FOR CANCER PROGNOSIS  
The invention provides compositions and methods for determining the likelihood of tumor recurrence of adjuvant cancer patients following surgical resection.
US20150197812 CIRCULATING miRNAs AS MARKERS FOR BREAST CANCER  
The present invention is directed to methods for diagnosing breast cancer, metastasizing breast cancer, or for determining the CTC status in a subject. Moreover, the present invention is concerned...
US20150088430 METHODS FOR EVALUATING LUNG CANCER STATUS  
The invention in some aspects provides methods of determining the likelihood that a subject has lung cancer based on the expression of informative-genes. In other aspects, the invention provides...
US20140329719 GENETIC VARIANTS FOR PREDICTING RISK OF BREAST CANCER  
The invention pertains to certain genetic variants that have been determined to be susceptibility variants of breast cancer. Methods of disease management, including diagnosing increased...
US20130190200 SNP FOR PREDICTING THE SENSITIVITY TO ANTICANCER TARGETED THERAPEUTIC FORMULATION  
The present invention relates to a single nucleotide polymorphism (SNP) for predicting the sensitivity to an anticancer targeted therapeutic formulation, a polynucleotide containing the same, and...
US20110319282 METHODS AND KITS FOR THE DIAGNOSIS AND THE STAGING OF COLORECTAL CANCER  
The invention relates to methods for the staging and the diagnosis of colorectal cancer based on the determination of the expression levels of a set of genes, the altered expression of which in...
US20110312532 Gene Expression Markers for Breast Cancer Prognosis  
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
US20120220478 METHODS FOR ASSESSING DISEASE RISK  
The invention relates to methods and biomarkers for assessing a subject's risk for a disease, such as cancer, an autoimmune disease or a neurological disease. In particular, the invention provides...
US20110009469 COMPOSITIONS AND METHODS OF TREATING NEOPLASIA  
The present invention provides compositions and methods featuring microRNA polynucleotides for the diagnosis, treatment or prevention of neoplasia.
US20120202705 ACUTE KIDNEY INJURY RISK TESTING  
The present invention relates to the method of determining the risk of acute kidney injury comprising determining the amount of one or more marker(s) selected from REN, SLC38A4, IL17RB, TMEM149,...
US20130029868 METHODS AND KITS FOR THE DETECTION OF CANCER INFILTRATION OF THE CENTRAL NERVOUS SYSTEM  
This invention relates to methods to detect the presence of cancer infiltration of the Central Nervous System (CNS) based on the detection of soluble proteins, preferably, in cerebrospinal fluid...