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US20150073035 BIOMARKERS AND USES THEREOF IN PROGNOSIS AND TREATMENT STRATEGIES FOR RIGHT-SIDE COLON CANCER DISEASE AND LEFT-SIDE COLON CANCER DISEASE  
Genetic biomarkers for left side colon cancer (LCC) (such as expression levels of an RNA transcript or expression product of NOX4, MMP3, or a combination) and right side colon cancer (RCC) (such...
US20120172244 BIOMARKERS AND USES THEREOF IN PROGNOSIS AND TREATMENT STRATEGIES FOR RIGHT-SIDE COLON CANCER DISEASE AND LEFT-SIDE COLON CANCER DISEASE  
Genetic biomarkers for left side colon cancer (LCC) (such as expression levels of an RNA transcript or expression product of NOX4, MMP3, or a combination) and right side colon cancer (RCC) (such...
US20150225792 COMPOSITIONS AND METHODS FOR IDENTIFYING DEPRESSIVE DISORDERS  
Provided herein are compositions, kits, and methods for the identification of depressive disorders. In particular, provided herein are compositions, kits, and methods for the detection or...
US20140378317 Amplification and Analysis of Selected Targets on Solid Supports  
Methods are provided for multiplexed amplification of selected targets and analysis of the amplified targets. In preferred aspects the amplification and analysis take place on the same solid...
US20110269631 Amplification and Analysis of Selected Targets on Solid Supports  
Methods are provided for multiplexed amplification of selected targets and analysis of the amplified targets. In preferred aspects the amplification and analysis take place on the same solid...
US20140121130 METHOD OF DETERMINING THE PROGNOSIS OF HEPATOCELLULAR CARCINOMAS USING A MULTIGENE SIGNATURE ASSOCIATED WITH METASTASIS  
Expression of MYC alone, in a conditional transgenic mouse model of Twist1- and MYC-induced hepatocellular carcinoma (HCC), resulted in tumors that failed to metastasize, whereas Twist1...
US20140011863 METHODS AND COMPOSITIONS FOR ASSESSMENT OF PULMONARY FUNCTION AND DISORDERS  
The present invention provides methods for the assessment of risk of developing chronic obstructive pulmonary disease (COPD), emphysema or both COPD and emphysema in smokers and non-smokers using...
US20130281319 METHODS AND COMPOSITIONS FOR ASSESSMENT OF PULMONARY FUNCTION AND DISORDERS  
The present invention provides methods for the assessment of risk of developing chronic obstructive pulmonary disease (COPD), emphysema or both COPD and emphysema in smokers and non-smokers using...
US20110184044 METHODS AND COMPOSITIONS FOR ASSESSMENT OF PULMONARY FUNCTION AND DISORDERS  
The present invention provides methods for the assessment of risk of developing chronic obstructive pulmonary disease (COPD), emphysema or both COPD and emphysema in smokers and non-smokers using...
US20120255044 URATE TRANSPORTER, AS WELL AS METHOD AND KIT FOR EVALUATING URATE TRANSPORT-RELATED DISEASE FACTOR AND INFLAMMATION-RELATED DISEASE FACTOR, AND TEST SAMPLE AND DRUG  
A method and evaluation kit are provided, in which a high-capacity urate transporter is identified to assist in the early treatment and prevention of urate transport-related disease and...
US20140274772 BIOMARKER PANEL FOR DETECTING LUNG CANCER  
A method and a kit for assessing risk of lung cancer versus benign disease in a subject are provided. The method includes obtaining a biological sample from the subject and determining a...
US20140309127 METHODS OF DETECTING BLADDER CANCER  
Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of detecting low grade bladder cancer are provided. In some embodiments, methods of monitoring...
US20120277112 PREDICTING RESPONSE TO ANTI-CANCER THERAPY VIA ARRAY COMPARATIVE GENOMIC HYBRIDIZATION  
Array comparative genomic hybridization classifiers, arrays comprising the classifiers, and related methods of using the same for predicting the therapeutic efficacy of anti-cancer therapy by...
US20130303400 MULTIMARKER PANEL  
The invention is directed to a method of diagnosing a malignant ovarian tumor disease in a subject, which comprises —providing a sample of peripheral blood cells (PBC) of the subject, —measuring...
US20130345077 DIAGNOSIS OF LYMPH NODE INVOLVEMENT IN RECTAL CANCER  
A method of determining the risk that a subject that has been diagnosed with rectal cancer has stage III rectal cancer is described. The method includes determining the expression levels of a...
US20150057160 PATHOGEN SCREENING  
The present invention relates to methods of isolating pathogenic genomes from a clinical sample.
US20140212415 HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION  
Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular classification of disease are provided.
US20130237444 GBM MOLECULAR CONTEXTS ASSOCIATED WITH PATIENT SURVIVAL  
This disclosure provides a glioblastoma biomarker profile comprising glioblastoma associated genetic aberrations. The profile is indicative of a cellular and physiological characteristic of a...
US20140213483 LABELED DEVICE  
A microarray is disclosed comprising a reaction zone and a labeling zone, wherein the at least one labeling zone contains a marker, such as an alphanumerical code, a binary code, a barcode, a 2D...
US20140080727 VARIANTS PREDICTIVE OF RISK OF GOUT  
Markers on chromosome 19q13, in particular, markers in the ALDH16A1 gene, are associated with risk of gout in humans. Diagnostic applications using the markers, such as determining the...
US20140315755 Genome-wide Antisense Oligonucleotide and RNAi  
The present invention relates to the generation and construction of libraries for genome-wide antisense oligonucleotide and siRNA.
US20140349886 PRIMERS AND KITS FOR COLONY MULTIPLEX PCR FOR THE DETECTION OF CLASS A, B, C, AND D BETA-LACTAMASE GENES AND METHODS OF USING THEREOF  
The present invention provides kits and primers for colony multiplex PCR for the detection of class A, B, C, and D β-lactamase genes. The rapid detection of bla genes by using the kits and primers...
US20150018235 Methods and Compositions for the Treatment and Diagnosis of Pancreatic Cancer  
The invention provides methods, compositions and kits for the detection and treatment of pancreatic cancer.
US20130210900 ARID1A and PPP2R1A Mutations in Cancer  
Two genes, ARID1A (AT-rich interactive domain-containing protein 1A) and PPP2R1A (protein-phosphatase 2, regulatory subunit 1, alpha), can be used in methods which are useful for detecting cancer,...
US20130274135 COMPOSITIONS OF TOEHOLD PRIMER DUPLEXES AND METHODS OF USE  
Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof.
US20110286997 Genetic Alterations on Chromosome 16 and Methods of Use Thereof for the Diagnosis and Treatment of Type 1 Diabetes  
Compositions and methods for the detection and treatment of T1D are provided.
US20110236370 Genetic Alterations on Chromosomes 21q, 6q and 15q and Methods of Use Thereof for the Diagnosis and Treatment of Type I Diabetes  
Compositions and methods for the detection and treatment of T1D are provided.
US20130116132 ALZHEIMER'S PROBE KIT  
Oligonucleotide probes for use in assessing gene transcript levels in a sample, which may be used in analytical techniques, particularly diagnostic techniques, are disclosed. Conveniently the...
US20110046005 METHOD AND NUCLEIC ACIDS FOR THE ANALYSIS OF COLON CELL PROLIFERATIVE DISORDERS  
Provided are methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders by analysis of one or more of the genes Versican, TPEF,...
US20120270743 Genetic Signatures and Gene Chips Associated With Administration of Electrically Conducted Radio Frequency Current to Skin and Methods and Treatments Relating Thereto  
A gene panel comprising genes regulated in mammalian skin in response to generation of a radio frequency current in a tissue volume of the mammalian skin sufficient to heat the tissue volume to a...
US20150005191 Compositions and Methods for Identifying Autism Spectrum Disorders  
The compositions and methods described are directed to gene chips having a plurality of different oligonucleotides with specificity for genes associated with autism spectrum disorders. The...
US20140349878 PACLITAXEL RESPONSE MARKERS FOR CANCER  
Cancer marker sets consisting of particular genes differentially expressed in tumours provide improved accuracy of predicting effectiveness of paclitaxel or paclitaxel-like drug treatment against...
US20120094845 METHODS AND DEVICES FOR ASSESSING INFERTILITY AND/OR EGG QUALITY  
The invention generally relates to methods and devices for assessing infertility. In certain embodiments, methods of the invention involve conducting an assay to determine presence or absence of a...
US20110071033 METHODS AND DEVICES FOR ASSESSING INFERTILITY AND/OR EGG QUALITY  
The invention generally relates to methods and devices for assessing infertility. In certain embodiments, methods of the invention involve conducting an assay to determine presence or absence of a...
US20130143770 CELLULAR ARRAYS AND METHODS OF DETECTING AND USING GENETIC DISORDER MARKERS  
A method is disclosed for rapid molecular profiling of tissue or other cellular specimens by placing a donor specimen in an assigned location in a recipient array, providing copies of the array,...
US20130035260 GENES INVOLVED IN INFLAMMATORY BOWEL DISEASES AND USE THEREOF  
The invention concerns genes involved in inflammatory and/or immune diseases and some cancers, in particular intestinal cryptogenic inflammatory diseases, and proteins coded by said genes. The...
US20140325702 Methods for genetic control of plant pest infestation and compositions thereof  
The present invention is directed to controlling plant pest infestation, and particularly plant nematode infestation, by inhibiting one or more biological functions in the plant pest. The...
US20130004482 Methods of Treating Breast Cancer with Anthracycline Therapy  
The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The...
US20140329710 TRANSCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT IN NEW ONSET HEART FAILURE  
A novel transcriptomic biomarker for prognosis in heart failure has a direct clinical application in prediction of prognosis in new onset heart failure, heart disease, heart disorders and...
US20120309637 METHODS AND COMPOSITIONS FOR RAPID MULTIPLEX AMPLIFICATION OF STR LOCI  
Provided are methods for multiplex polymerase chain reaction (PCR) amplification of short tandem repeat (STR) loci that can be used to rapidly generate a highly specific STR profile from target...
US20120065083 METHOD AND APPARATUS FOR PREDICTING SUSCEPTIBILITY TO A DEVELOPMENTAL DISORDER  
The present invention provides a method of screening a subject for mutations in the TRAPPC9 gene that are associated with developmental disabilities. The present invention also provides proteins...
US20110124525 METHOD FOR PREDICTING RISK OF METASTASIS  
The invention encompasses methods and compositions for predicting the risk of metastasis. In particular, the invention encompasses a method for correlating the the level of expression of one or...
US20130116140 METHODS AND MATERIALS FOR DETERMINING THE EFFICACY OF PROSTATE CANCER THERAPIES  
Methods for monitoring, and determining the efficacy of, a treatment for prostate cancer in a subject are provided, such methods including detecting the levels of expression of multiple...
US20120053070 Genetic Risk Analysis In Reward Deficiency Syndrome  
Methods and kits for performing genetic analyses of biological samples to assess predisposition for and/or to stratify risk Reward Deficiency Syndrome (RDS) behavior, including various addictive...
US20140228231 METHOD TO ESTIMATE AGE OF INDIVIDUAL BASED ON EPIGENETIC MARKERS IN BIOLOGICAL SAMPLE  
The invention provides methods and materials that use observation of DNA characteristics to obtain information relating to the age of individuals. The instant disclosure identifies 88 sites in or...
US20130184172 Bladder Cancer Detection Composition, Kit and Associated Methods  
Compositions, kits, and methods for the diagnosis, prognosis, and monitoring of bladder cancer in a subject are provided by detecting in a urine sample a combination of biomarkers. In one...
US20110183859 INFLAMMATORY GENES AND MICRORNA-21 AS BIOMARKERS FOR COLON CANCER PROGNOSIS  
Disclosed herein are methods for detecting a more aggressive form of a colon adenocarcinoma in a subject, thereby predicting the prognosis of the subject. The methods generally include determining...
US20130012403 Compositions and Methods for Identifying Autism Spectrum Disorders  
The compositions and methods described are directed to microRNA chips having a plurality of different oligonucleotides with specificity for genes associated with autism spectrum disorders. The...
US20100298407 COMPOSITIONS AND METHODS FEATURING MICRONAS FOR TREATING NEOPLASIA  
The invention provides compositions and methods for the treatment of a neoplasia. The methods of the invention involve expressing a microRNA usually repressed by Myc in a cell of a subject...
US20140011701 Prognostic Marker Sets For Prostate Cancer  
Prostate cancer marker sets consisting of particular genes differentially expressed in prostate tumours provide improved accuracy of prostate cancer prognosis. The prostate cancer marker sets of...