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US20120077683 KIT AND METHOD FOR PREDICTING CYTARABINE SENSITIVY OF PATIENT HAVING ACUTE MYELOID LEUKEMIA  
A kit and method for predicting cytarabine sensitivity of patients having acute myeloid leukemia are disclosed.
US20110245095 FAST ASSIGNMENT OF ADEQUATE CHEMOTHERAPY WITH LATINUM BASED DRUGS FOR CANCER PATIENTS BASED ON THE IDENTIFICATION OF CONSTITUTIONAL BRCAL MUTATIONS  
A new method to improve therapy outcome depending on a particular constitutional genotype have been disclosed. Subject of invention allows to synthesize DNA and identification of germline BRCA1...
US20130267437 USE OF SPECIFIC GENES OR THEIR ENCODED PROTEINS FOR A PROGNOSIS METHOD OF CLASSIFIED LUNG CANCER  
At least one element for the implementation of a prognosis method, preferably in vitro, of the survival rate of a patient afflicted by a lung cancer, the lung cancer being previously classified as...
US20140121133 SERUM/PLASMA MicroRNAs AND USES THEREOF  
This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably...
US20130071408 Methods for Diagnosis and Treatment of Non-Insulin Dependent Diabetes Mellitus  
Methods and compositions are provided for the treatment and diagnosis of diseases related to hyperglycemic conditions, including diabetes, insulin resistance, and the like. Genetic polymorphisms...
US20150259673 Library Compositions and Methods for Acyclic Identification of Aptamers  
The present invention provides improved aptamer libraries useful for discovery of aptamers that have high binding affinity for a single or a plurality of targets. The libraries contain higher...
US20130217582 Library Compositions and Methods for Acyclic Identification of Aptamers  
The present invention provides improved aptamer libraries useful for discovery of aptamers that have high binding affinity for a single or a plurality of targets. The libraries contain higher...
US20120184455 Method and Nucleic Acids for the Improved Treatment of Breast Cell Proliferative Disorders  
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for...
US20130315931 CXCR4 as a Susceptibility Locus in Juvenile Idiopathic Arthritis (JIA) and Methods of Use Thereof for the Treatment and Diagnosis of the Same  
Compositions and methods useful for the diagnosis and treatment of juvenile idiopathic arthritis are disclosed.
US20130261006 Method of Generating a Hyperpigmentation Condition Gene Expression Signature  
A method of generating a hyperpigmentation condition gene expression signature for use in identifying connections between perturbagens and genes associated with a skin pigmentation condition. The...
US20110091892 Methods for the Diagnosis and Treatment of Lung Cancer  
The present invention provides methods for aiding in the diagnoses of the neoplastic condition of a lung cell and methods of screening for a potential therapeutic agent for the reversal of the...
US20150094357 Methods for Differentiating Pancreatic Cancer from Normal Pancreatic Function and/or Chronic Pancreatitis  
There is provided herein methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer, along with methods of identifying anti-pancreatic cancer agents.
US20140221244 Methods and Compositions for the Treatment and Diagnosis of Colorectal Cancer  
The invention provides methods, compositions and kits relating to the detection, diagnosis, treatment of colorectal cancer.
US20120251451 Renal Cell Carcinoma Biomarkers  
The invention provides markers for renal cancer, polynucleotides encoding same, and precursors thereof. The invention also provides methods for detecting, diagnosing, screening for, monitoring,...
US20120258878 PROGNOSTIC GENE SIGNATURES FOR NON-SMALL CELL LUNG CANCER  
The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups by way of a multigene signature, comprising at least 5 genes...
US20130331298 ANALYZER AND DISPOSABLE CARTRIDGE FOR MOLECULAR IN VITRO DIAGNOSTICS  
An in vitro diagnostics analyzer and assay cartridge for carrying out biochemical assays is disclosed. The analyzer includes a tilted clamp assembly for holding an assay cartridge, upper and lower...
US20110082188 GENE EXPRESSION PROFILING OF INFLAMMATORY BOWEL DISEASE  
The present invention relates to methods for identifying and/or classifying patients with inflammatory bowel diseases (IBD), particularly patients with Crohn's disease or ulcerative colitis. Gene...
US20130072401 METHOD AND KIT FOR THE PROGNOSIS OF COLORECTAL CANCER  
A method and kit for the prognosis of colorectal cancer where the method includes the steps of: a) obtaining a peripheral blood sample and extracting total RNA from the sample, b) contacting the...
US20150004158 Compositions, Kits, and Methods for the Identification, Assessment, Prevention, and Therapy of Cancer  
The present invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating cancer (e.g., hematological malignancies in humans). A variety of biomarker...
US20120015049 MICRORNA BIOMARKER IN CANCER  
This invention provides compositions and methods for predicting and improving a chemotherapy response to treat an ovarian cancer. In one embodiment, the invention provides compositions and methods...
US20130143764 METHOD FOR CLASSIFYING AN INFLAMMATORY BOWEL DISEASE AS A CROHN'S DISEASE OR AS AN ULCERATIVE COLITIS  
The present invention relates to a method for classifying an inflammatory bowel disease in a patient as a Crohn's disease or as an ulcerative colitis, said method comprising a step of measuring an...
US20120208714 DNA-BASED METHODS FOR CLONE-SPECIFIC IDENTIFICATION OF STAPHYLOCOCCUS AUREUS  
MRSA CC398 is a clone of S. aureus that has recently emerged in pigs and other domestic animals worldwide. As any other MRSA, the clone displays high levels of antibiotic resistance and poses a...
US20120035067 Marker Panels For Idiopathic Pulmonary Fibrosis Diagnosis And Evaluation  
The present invention relates to the discovery that of a panel of serum or plasma markers may be used to diagnose Idiopathic Pulmonary Fibrosis (“IPF”) and distinguish this condition from other...
US20140221230 THROMBOEMBOLIC DISEASE MARKERS  
The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for...
US20120122711 SCREENING OF BIOPOLYMERS  
Described herein are inventive compositions and methods relating to sampling of biopolymers and, in particular, to fractional sampling of biopolymers. In one aspect, embodiments are generally...
US20110262025 Cosmetic Compositions and Methods for Maintaining and Improving Barrier Function of the Stratum Corneum and to Reduce the Visible Signs of Aging in Skin  
Gene panels, biomarker panels and microarrays relating to lipid formation in stratum corneum of human skin as a function of extrinsic and/or intrinsic aging conditions, and methods for assessing...
US20120220485 PROBE SET AND METHOD FOR IDENTIFYING HLA ALLELE  
Provided is a probe set that is useful for identifying each allele of HLA individually, and a method of identification of an allele of HLA by the use thereof for each type. The probe set is...
US20110130295 Diagnostic Methods For Determining Prognosis Of Non-Small Cell Lung Cancer  
Disclosed are methods for identifying early-stage non-small-cell lung cancer (NSCLC) patients who will have an unfavorable prognosis for the recurrence of lung cancer after surgical resection. The...
US20130296175 Genetic Variants as Markers for Use in Urinary Bladder Cancer Risk Assessment, Diagnosis, Prognosis and Treatment  
Polymorphic variants that have been found to be associated with risk of urinary bladder cancer are provided herein. Such polymorphic markers are useful for diagnostic purposes, such as in methods...
US20130315858 Common and Rare Genetic Variations Associated with Common Variable Immunodeficiency (CVID) and Methods of Use Thereof for the Treatment and Diagnosis of the Same  
Compositions and methods useful for the diagnosis and treatment of common variable immunodeficiency are disclosed.
US20120142544 DIAGNOSTIC TRANSCRIPTOMIC BIOMARKERS IN INFLAMMATORY CARDIOMYOPATHIES  
Molecular signatures that function as very sensitive diagnostic biomarker for myocarditis, heart disease and disorders thereof, are identified.
US20150232937 METHODS AND GENOTYPING PANELS FOR DETECTING ALLELES, GENOMES, AND TRANSCRIPTOMES  
Disclosed are methods and genotyping panels for detecting alleles, genomes, and transcriptomes in admixtures of two individuals.
US20110086769 METHODS AND GENOTYPING PANELS FOR DETECTING ALLELES, GENOMES, AND TRANSCRIPTOMES  
Disclosed are methods and genotyping panels for detecting alleles, genomes, and transcriptomes in admixtures of two individuals.
US20120231970 COLON CANCER MARKER AND METHOD FOR TESTING FOR COLON CANCER  
Provided are a micro RNA which can be used as a colon cancer marker, a method for testing for colon cancer which uses the micro RNA which can be used as a colon cancer marker, and a test kit which...
US20130237456 MARKER CONSISTING OF PLASMA MICRORNA AND A NEW METHOD FOR DIAGNOSIS OF HEPATOCELLULAR CARCINOMA  
The present invention relates to a kit for diagnosing hepatocellular carcinoma consisting of plasma microRNA, a kit containing the same, and a new method therefor. The marker for diagnosing...
US20140066335 Method of preparing libraries of template polynucleotides  
The present invention relates to a method for preparing a library of template polynucleotides and use thereof in methods of solid-phase nucleic acid amplification. More specifically, the invention...
US20150260728 Method for Diagnosing a Molecular Phenotype of a Patient Suffering From an Illness Accompanied by Chronic Inflammation  
Chronic inflammation is an increasing medical problem area of high socioeconomic significance. The invention relates to a method and a kit for diagnosing a molecular phenotype of a patient...
US20150111782 Methods for Diagnosing and Treating Eye-Length Related Disorders  
The invention provides to methods for diagnosing eye-length related disorders, including myopia. The invention also provides methods for treating and limiting eye-length related disorders,...
US20120182520 Methods for Diagnosing and Treating Eye-Length Related Disorders  
The invention provides to methods for diagnosing eye-length related disorders, including myopia. The invention also provides methods for treating and limiting eye-length related disorders,...
US20140357660 GENE EXPRESSION SIGNATURES OF NEOPLASM RESPONSIVENESS TO THERAPY  
Gene signatures for determining whether a neoplasm (such as a multiple myeloma neoplasm) is sensitive to mTORi/HDACi combination therapy and/or for determining the prognosis of a neoplasm in a...
US20130084241 DEVELOPMENT OF miRNA DIAGNOSTICS TOOLS IN BLADDER CANCER  
The present invention includes methods and compositions related to diagnosis of bladder cancer, including the presence of bladder cancer and/or the type or stage of bladder cancer. In specific...
US20130023430 CANCER STEM CELL GENE VARIANTS ARE ASSOCIATED WITH TUMOR RECURRENCE  
The disclosure provides compositions and methods for determining the likely tumor recurrence in cancer patients by screening CD44, CD166 and/or LGR5 polymorphism in samples isolated from the patient.
US20140200153 METHODS OF DETECTING LUNG CANCER  
Methods of lung cancer in a sample from a patient are provided. Methods of detecting changes in expression of one or more target RNAs associated with lung cancer are also provided. Compositions...
US20130157886 METHODS OF DETECTING LUNG CANCER  
Methods of lung cancer in a sample from a patient are provided. Methods of detecting changes in expression of one or more target RNAs associated with lung cancer are also provided. Compositions...
US20130316935 METHOD TO DETERMINE RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS  
Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will...
US20110224089 GENE EXPRESSION SIGNATURE OF GENOMIC INSTABILITY IN BREAST CANCER  
Methods of assessing genomic instability in breast cancer tissue by measuring the expression level of genes CDKN2A, SCYA18, STK15, NXF1, cDNA Dkfzp762M127, p28 KIAA0882, MYB, Human clone 23948,...
US20120282245 BIOMARKERS AND ASSAYS FOR THE TREATMENT OF CANCER  
This invention features methods for prognosticating the efficacy of a cancer treatment comprising administration of a lymphotoxin-β receptor (LT-β-R) using TRAF3, TRAF2, and/or p53 markers, as...
US20120088687 MicroRNAs (miRNA) as Biomarkers for the Identification of Familial and Non-Familial Colorectal Cancer  
A technique for the analysis of global miRNA signatures including a larger panel of miRNAs in various groups of well-characterized colorectal cancers (CRCs) is described in the instant invention....
US20110218121 GENE ASSOCIATED WITH LIVER CANCER, AND METHOD FOR DETERMINATION OF THE RISK OF ACQUIRING LIVER CANCER  
Provided are a method for detecting early-stage liver cancer and determining a risk of liver cancer by using blood collected from a patient with imposing a less burden on the patient; and a gene...
US20130281313 PROGNOSTIC AND/OR PREDICTIVE BIOMARKERS AND BIOLOGICAL APPLICATIONS THEREOF  
The present invention relates to the fields of genetics, immunology and medicine. The present invention more specifically relates to the identification of human genes and expression products...