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US20140206574 Methods and Compositons for the Treatment and Diagnosis of Cancer  
The invention relates to methods of detecting cancer in a sample obtained from a subject. The invention also provides kits and reagents for detecting cancer as well as therapeutics and methods of...
US20110046006 MEANS AND METHODS FOR TYPING A CELL ISOLATE OF AN INDIVIDUAL SUFFERING FROM A PSYCHIATRIC DISORDER OR AT RISK OF SUFFERING THERE FROM  
The present invention relates to a method for typing a cell isolate of an individual suffering from a pychiatric disorder, or at risk for suffering there from, the method comprising providing an...
US20130189243 BIOMARKERS FOR ACUTE ISCHEMIC STROKE  
The present invention provides methods and compositions for the diagnosis of acute ischemic stroke. The invention further provides methods and compositions for distinguishing acute ischemic stroke...
US20130143753 METHODS FOR PREDICTING OUTCOME OF BREAST CANCER, AND/OR RISK OF RELAPSE, RESPONSE OR SURVIVAL OF A PATIENT SUFFERING THEREFROM  
The present invention relates to biomarkers allowing predicting breast tumor and solid tumor outcome using hypoxia related genes. More specifically, the present invention relates to a method for...
US20130005610 TOXICITY-ASSOCIATED GENES, GENETIC VARIANTS, AND USE THEREOF  
Genes and genetic variants in human genomes are disclosed which are useful, inter alia, as diagnostic biomarkers.
US20150038357 PROGNOSIS FOR GLIOMA  
Disclosed is a method of determining the survival prognosis of a patient afflicted by a glioma. The method includes assessing the level of expression of one or more specific gene in cells of the...
US20110160091 Methods and Nucleic Acids for Analyses of Cell Proliferative Disorders  
The invention provides methods, nucleic acids and kits for determining the prognosis of a subject having cell proliferative disorder, preferably cancer. The invention discloses genomic sequences...
US20130023439 Method and Kit for Determining Sensitivity to Decitabine Treatment  
The present invention is a gene expression panel of chemotherapeutic drug-resistant cancer stem cells comprising RIN1, SOX15 and TLR4. In one embodiment the cancer stem cells are testicular cancer...
US20150038351 Gene Signatures That Predispose Or Protect Individuals From Low-Dose Radiation Induced Breast Cancer Or Are Associated with Disease-Free Survival  
A method for identifying sensitivity to low-dose ionizing radiation and cancer patient prognosis. Several predictor panels of genes that are predictive for increased or decreased susceptibility...
US20120201837 USE OF EIF3M FOR THE DIAGNOSIS AND TREATMENT OF CANCER  
Disclosed are a cancer marker-detecting composition comprising an agent for measuring an mRNA or protein expression level of eIF3m, a cancer diagnosis kit comprising the same, a method for...
US20120028816 METHODS AND SYSTEMS FOR SCREENING FOR AND DIAGNOSING DNA METHYLATION ASSOCIATED WITH AUTISM SPECTRUM DISORDERS  
Methods and systems for population screening and diagnostics are provided. In particular methods and systems for population screening of individuals for genetic disorders due to alterations in DNA...
US20110287968 Methylation Assay  
The present invention discloses a method of generating subsets of methylation specific markers from a set, having diagnostic power for various diseases, e.g. cancer of thyroid, breast, colon, or...
US20100323922 siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)  
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
US20120277999 METHODS, KITS AND ARRAYS FOR SCREENING FOR, PREDICTING AND IDENTIFYING DONORS FOR HEMATOPOIETIC CELL TRANSPLANTATION, AND PREDICTING RISK OF HEMATOPOIETIC CELL TRANSPLANT (HCT) TO INDUCE GRAFT VS. HOST DISEASE (GVHD)  
The invention relates to predicting or determining risk of a hematopoietic cell transplant (HCT) from a donor to induce Graft vs. Host Disease (GVHD) in a HCT recipient; to classifying HCT from a...
US20130296178 METHODS FOR GENETIC ANALYSIS  
Methods of treating an individual exhibiting a medical condition are disclosed. The methods involve determining a score of an individual based on the individual's genotypic information, comparing...
US20110059016 OPTICAL ASSAY SYSTEM WITH A MULTI-PROBE IMAGING ARRAY  
The subject matter described herein relates to an optical assay system having a multi-probe imaging array that orients a plurality of probes with respect to one another and to a sample. According...
US20150247206 Compositions and Methods for Therapy and Diagnosis of Cancer and Cancer Metastasis  
The present invention relates to methods which make possible to assess and/or prognose a cancer disease, the metastatic behaviour of a cancer disease and/or the occurrence of a relapse of cancer....
US20130039908 PROGNOSTIC MARKERS AND METHODS FOR PROSTATE CANCER  
The present invention relates to methods and compositions for the diagnosis, prognosis and treatment of neoplastic disorders. Some embodiments include methods, compositions, and kits for the...
US20150133319 COMPOSITIONS AND KITS FOR MOLECULAR COUNTING  
Methods, kits and systems are disclosed for analyzing one or more molecules in a sample. Analyzing the one or more molecules may comprise quantitation of the one or more molecules. Individual...
US20110287961 EXPRESSION ANALYSIS OF CORONARY ARTERY ATHEROSCLEROSIS  
This invention relates, e.g., to a method for screening a subject for the presence of coronary atherosclerosis, said method comprising measuring the expression level of at least 5 of the genes of...
US20140057802 METHOD AND KIT FOR DETERMINING IN VITRO THE PROBABILITY FOR AN INDIVIDUAL TO SUFFER FROM COLORECTAL CANCER  
The present invention provides a method for determining in vitro, in a peripheral blood sample, the probability for an individual to suffer from a colorectal cancer, using the comparison of the...
US20150176078 PROSTATE CANCER GENE EXPRESSION PROFILES  
The present disclosure provides gene expression profiles that are associated with prostate cancer. The gene expression profiles can be used to detect prostate cancer cells in a sample and to...
US20120208706 OPTIMIZATION OF MULTIGENE ANALYSIS OF TUMOR SAMPLES  
A method of analyzing a tumor sample comprising: (a) acquiring a library comprising a plurality of tumor members from a tumor sample;(b) contacting the library with a bait set to provide selected...
US20130203814 Association of Rare Recurrent Genetic Variations to Attention-Deficit, Hyperactivity Disorder (ADHD) and Methods of Use Thereof for the Diagnosis and Treatment of the Same  
Compositions and methods for the detection and treatment of ADHD are provided.
US20150072878 Stratification of Left-Side and Right-Side Colon Cancer  
Compositions/methods for employing fresh-frozen or FFPE colon cancer tissue in left side colon cancer (LCC) and right-side colon cancer (RCC) disease patients for risk of relapse...
US20110105466 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PSYCHOTIC DISORDERS THROUGH THE IDENTIFICATION OF THE SULT4A1-1 HAPLOTYPE  
Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1...
US20120040848 MOLECULAR SIGNATURE OF LIVER TUMOR GRADE AND USE TO EVALUATE PROGNOSIS AND THERAPEUTIC REGIMEN  
The present invention concerns a method to determine the gene expression profile on a sample previously obtained from a patient diagnosed for a liver tumor, comprising assaying the expression of a...
US20110183862 MOLECULAR SIGNATURE OF LIVER TUMOR GRADE AND USE TO EVALUATE PROGNOSIS AND THERAPEUTIC REGIMEN  
The present invention concerns a method to determine the gene expression profile on a sample previously obtained from a patient diagnosed for a liver tumor, comprising assaying the expression of a...
US20130267438 USE OF SPECIFIC GENES FOR THE PROGNOSIS OF LUNG CANCER AND THE CORRESPONDING PROGNOSIS METHOD  
At least 13 genes chosen among a set of 28 genes for carrying out a method for identifying at least 66% of patients of those having a survival rate of at most about 20% at 30 months, among a...
US20120178641 GLOBAL MAPPING OF PROTEIN-DNA INTERACTION BY DIGITAL GENOMIC FOOTPRINTING  
The present invention provides a method for globally mapping a genome for its protein-binding pattern. A computer system useful for this purpose is also described.
US20130090261 Device for Determining or Studying the State of Stimulation of the Natural Defences of Plants or Portions of Plants  
The present invention relates to a device for determining or studying the state of stimulation of the natural defenses of plants or plant portions, which plants advantageously belong to the...
US20150045255 Endometrial Phase or Endometrial Cancer Biomarkers  
Methods for detecting endometrial diseases or an endometrium phase in a subject are described comprising measuring endometrial markers or polynucleotides encoding the markers in a sample from the...
US20130130925 TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS  
The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a...
US20120225796 TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS  
The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a...
US20110160079 TOOL FOR DIAGNOSIS AND PROGNOSIS OF MATURE B-CELL NEOPLASMS  
The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray can include a...
US20120258074 Systems, Models and Methods for Identifying and Evaluating Skin-Active Agents Effective for Treating Dandruff/Seborrheic Dermatitis  
Methods and systems for determining functional relationships between a skin-active agent and a skin condition of interest, and methods and systems for identifying cosmetic agents effective for...
US20150259751 MOLECULAR SIGNATURE FOR AGGRESSIVE SQUAMOUS CELL CARCINOMAS OF THE HEAD AND NECK  
The present invention encompasses methods of classifying HNSCC tumors, such as OSCC tumors, as aggressive or, alternatively, indolent.
US20140024552 COMPOSITIONS AND METHODS FOR DIAGNOSING OVARIAN CANCER  
The invention provides methods and compositions for distinguishing ovarian cancer from a benign pelvic mass using two or more of the following biomarkers: IL-6, MMP9, tPA, IGFBP2, MMP7, Tenascin,...
US20110059074 Knowledge-Based Proliferation Signatures and Methods of Use  
The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a...
US20140179563 Method and Nucleic Acids for the Analysis of Colorectal Cell Proliferative Disorders  
The invention provides methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders as well as therapy thereof by analysis of the gene EYA4...
US20130303397 OLIGONUCLEOTIDE PROBE SET AND METHODS OF MICROBIOTA PROFILING  
Described herein is a set of oligonucleotide probes. Also included are methods of using the oligonucleotide probes in profiling the microbiota of the GI tract of a subject and methods of...
US20130324435 ESOPHAGEAL CYTOKINE EXPRESSION PROFILES IN EOSINOPHILIC ESOPHAGITIS  
Methods and compositions disclosed herein generally relate to methods of providing or enhancing a diagnosis of eosinophilic esophagitis (EE). In particular, the invention relates to obtaining a...
US20130078244 METHODS FOR DETECTING AND REGULATING ALOPECIA AREATA AND GENE COHORTS THEREOF  
The invention provides for methods for controlling hair growth by administering a HLDGC modulating compound to a subject. The invention further provides for a method for screening compounds that...
US20140038837 BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER  
The present invention provides methods and compositions for detecting early stage ovarian cancer in a patient. Also, methods for evaluating the ovarian cancer state of a patient are described...
US20110086389 Compositions and Methods for Expressing In-Frame Multimeric Proteins  
The present invention concerns methods and compositions for making and using multimeric, single chain proteins of a defined structure. In various embodiments the invention involves a bank or...
US20120309641 DIAGNOSTIC KITS, GENETIC MARKERS, AND METHODS FOR SCD OR SCA THERAPY SELECTION  
Variations in certain genomic sequences useful as genetic markers of Sudden Cardiac Death (“SCD”), or Sudden Cardiac Arrest (“SCA”) risk, are described. Novel diagnostic kits and methods employing...
US20130022593 METHODS OF DIAGNOSING ENDOMETRIOSIS  
The present invention provides biomarkers for the diagnosis and prognosis of endometriosis. Generally, the methods of this invention find use in diagnosing or for providing a prognosis for...
US20150184238 DNA SEQUENCING  
Provided herein is technology relating to sequencing nucleic acids and particularly, but not exclusively, to methods, compositions, systems, and kits for sequencing a nucleic acid using a...
US20150133325 METHODS OF DETECTING BLADDER CANCER  
Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of monitoring recurrence of bladder cancer are provided. In some embodiments, the methods comprise...
US20110171200 PROTEIN C RS2069915 AS A RESPONSE PREDICTOR TO SURVIVAL AND ADMINISTRATION OF ACTIVATED PROTEIN C OR PROTEIN C-LIKE COMPOUND  
Provided herein are methods, oligonucleotides and peptide nucleic acids, compositions and kits for predicting a subject's response to treatment with activated protein C or protein C-like compound...