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US20120122726 MARKERS FOR ENDOMETRIAL CANCER  
The invention relates to the surprising finding that biomarkers corresponding to ACAA1, AP1M2, CGN, DDR1, EPS8L2, FASTKD1, GMIP, IKBKE, P2RX4, P4HB, PHKG2, PPFIBP2, PPP1 R16A, RASSF7, RNF183,...
US20140094379 Colon Cancer Gene Expression Signatures and Methods of Use  
A gene expression signature of colon cancer, microarrays including them and methods of using the colon gene expression signature are provided. The gene expression signature is especially useful...
US20110111970 MICROCHIP FOR IDENTIFYING PHELLINUS SPECIES AND THE METHOD THEREOF  
The developed oligonucleotide microchip for simultaneous, rapid identification of multiple crucial forest Phellinus pathogens was based on the DIG or biotin-labeled specific probes derived form...
US20110118131 METHODS AND MATERIALS FOR TARGETED MUTAGENESIS  
The present disclosure relates to methods and materials for mutagenesis, including for the generation of novel or improved proteins and libraries or arrays of mutant proteins or nucleic acids...
US20120258877 IDENTIFICATION OF CANCER BIOMARKERS AND PHOSPHORYLATED PROTEINS  
Methods are provided for identifying proteins that are differentially expressed in disease state and normal cells. Stable isotope labeling of cells in culture allows for the identification of a...
US20150211073 MRNA-BASED GENE EXPRESSION FOR PERSONALIZING PATIENT CANCER THERAPY WITH AN MDM2 ANTAGONIST  
Use of at least an MDM2 gene panel, preferably a four gene MDM2 gene panel, as a biomarker for predicting the response to a MDM2 antagonist.
US20120065096 GENOTYPING TOOL FOR IMPROVING THE PROGNOSTIC AND CLINICAL MANAGEMENT OF MS PATIENTS  
The invention relates to methods of evaluating MS severity based on analysis of single nucleotide polymorphisms (SNPs) and to products and kits for use in such methods. The methods include a...
US20130336969 USE OF OLFACTOMEDIN-4 PROTEIN (OLFM4) IN COLORECTAL CANCER DIAGNOSIS  
The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting...
US20120053131 METHODS OF PREDICTING MEDICALLY REFRACTIVE ULCERATIVE COLITIS (MR-UC) REQUIRING COLECTOMY  
Disclosed are methods of predicting the development of medically refractory ulcerative colitis (MR-UC) in a patient In one embodiment, disclosed is a method of prognosing ulcerative colitis in an...
US20100048422 Methods of Producing Modified Assembly Lines and Related Compositions  
The present invention provides a method producing a modified assembly line, such as those that produce non-ribosomal peptides and polyketides. The modified assembly lines of the invention can be...
US20110319289 MOLECULAR-BASED METHOD OF CANCER DIAGNOSIS AND PROGNOSIS  
A gene profiling signature for diagnosis and prognosis of cancer patients is disclosed herein. In one embodiment, the gene signature includes 32 or 79 cancer survival factor-associated genes....
US20140017230 CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) BIOMARKERS  
The present application describes chronic lymphocytic leukemia (CLL) biomarkers. In particular, the invention concerns miRNA151 3p, miRNA409 3p, PTK2, and/or PI3K as biomarkers for patient...
US20140011694 METHODS, SYSTEMS, DATABASES, KITS AND ARRAYS FOR SCREENING FOR AND PREDICTING THE RISK OF AN IDENTIFYING THE PRESENCE OF TUMORS AND CANCERS  
The invention relates to predicting or determining risk of a tumor or cancer, or the presence or absence of a tumor or cancer, in a subject. The invention also relates to methods of correlating...
US20140031243 MULTIPLEX DETECTION OF MOLECULAR SPECIES IN CELLS BY SUPER-RESOLUTION IMAGING AND COMBINATORIAL LABELING  
Methods and systems are provided for creating molecular barcodes or indicia for cellular constituents within single cells and for resolving such barcodes or indicia with super-resolution...
US20110177974 NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS  
The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree...
US20140303009 Compositions, Methods, and Kits for Identifying Candidate Molecules from Encoded Chemical Libraries  
The subject matter relates to relates to a one-bead-one-sequence composition, a library of tagged chemicals comprising a plurality of one-bead-one-sequence compositions, a method for identifying a...
US20120021940 Compositions, Methods, and Kits for Identifying Candidate Molecules from Encoded Chemical Libraries  
The subject matter relates to relates to a one-bead-one-sequence composition, a library of tagged chemicals comprising a plurality of one-bead-one-sequence compositions, a method for identifying a...
US20150011411 BIOMARKERS OF CANCER  
The present invention relates to identification of a transcriptional signature of RalA and RalB GTPase proteins that is present in human cancer cells, and methods of treating the cancer, methods...
US20130259858 Signature for Predicting Clinical Outcome in Human HER2+ Breast Cancer  
A method of predicting outcome in a subject with for example Her2+ (ERα−) breast cancer comprising: a. determining a HTICs expression signature comprising determining an expression level of 2 or...
US20130157893 METHOD FOR PREDICTING THERAPEUTIC EFFECT OF IMMUNOTHERAPY ON CANCER PATIENT, AND GENE SET AND KIT TO BE USED IN THE METHOD  
Provided is a gene set which is useful for predicting the therapeutic effect of an immunotherapy on a cancer patient. Also provided is a method for examining whether an immunotherapy is...
US20150038552 ESOPHAGEAL MICRORNA EXPRESSION PROFILES IN EOSINOPHILIC ESOPHAGITIS  
Methods and compositions disclosed herein generally relate to methods of treating eosinophilic esophagitis (EE) and eosinophilic disorders by providing or enhancing a diagnosis of EE and...
US20130236567 GENE EXPRESSION SIGNATURE AS A PREDICTOR OF CHEMOTHERAPEUTIC RESPONSE IN BREAST CANCER  
Disclosed are methods and compositions for determining and/or predicting a response to a therapy, especially a cancer therapy, including chemotherapy. Specifically, the disclosure provides...
US20150247189 Diagnostic Methods and Markers for Bacterial Vaginosis  
A method of diagnosing bacterial vaginosis in a woman, which involves determining an amount of each of more than one BV-associated bacterium in a vaginal sample obtained from the female and...
US20120065085 Detection of chromosomal abnormalities associated with endometrial cancer  
The methods and compositions described herein address the need for diagnostic method that could be offered to women during yearly checkups to allow for early detection, diagnosis and...
US20120230952 DETECTION OF BLADDER CANCER  
Provided are methods for detecting bladder cancer in a subject. In some aspects, methylation of one or more of MYO3A, CA10, NKX6-2, SOX11, DBC1, NPTX2, and/or A2BP1 in DNA sediment from a urine...
US20150065378 SYNTHETIC OLIGONUCLEOTIDES FOR DETECTION OF NUCLEIC ACID BINDING PROTEINS  
Synthetic oligonucleotides that comprise a nucleic acid binding protein binding site, PCR primer sequences, and tag sequences that do not bind to nucleic acid binding proteins, with a total length...
US20120264639 METHODS AND COMPOSITIONS FOR PREDICTING SURVIVAL IN SUBJECTS WITH CANCER  
Methods for generating a prognostic signature for a subject with pancreatic ductal adenocarcinoma (PDAC) are disclosed. In some embodiments, the methods include determining expression levels for...
US20120283114 NEW DIAGNOSTIC TOOLS FOR ALZHEIMER DISEASE  
The present invention relates to development, validation and application of new sets of biomarkers for diagnosis of Alzheimer's disease (AD) and related disorders including early diagnosis of MCI...
US20140106985 MICRORNA BIOMARKERS FOR PROGNOSIS OF PATIENTS WITH PANCREATIC CANCER  
The present invention relates to prognostic micro RNA (miRNA) biomarkers based on a specific miRNA expression pattern, which can prove as a valuable prognostic tool to predict the survival of...
US20140329701 KIAA1456 EXPRESSION PREDICTS SURVIVAL IN PATIENTS WITH COLON CANCER  
The invention relates to methods for deciding on the therapy in a subject suffering from colorectal cancer as well as for predicting the clinical outcome of a patient which suffers from colorectal...
US20150087527 METHOD AND KIT FOR THE CLASSIFICATION AND PROGNOSIS OF TISSUE OR ORGAN FIBROSIS IN A REPARATIVE OR REACTIVE PROCESS  
The invention relates to methods of diagnosis or prognosis of a tissue or organ fibrosis (e.g., skin fibrosis, hypertrophic scar or a keloid) in a reparative or reactive process comprising the...
US20140031254 DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH ENDOMETRIAL CANCER  
The methods and compositions described herein address the need for diagnostic method that could be offered to women during yearly checkups to allow for early detection, diagnosis and...
US20110230372 GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUTCOME PREDICTION IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA  
The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high...
US20120329662 HYPOXIA TUMOUR MARKERS  
The present invention relates to a method for assessing a hypoxia phenotype of a tumour of a subject in which the gene expression of between 3 and 50 hypoxia-related genes of a sample obtained...
US20120117685 Isolated Novel Nucleic Acid and Protein Molecules from Soybeans and Methods of Using Thos Molecules  
This disclosure provides purified nucleic acids and polypeptides and various uses of these sequences such as transcript profiling. Also provided are transgenic plants, seeds, and plant cells...
US20120282167 METHOD FOR PREDICTING THE SENSITIVITY OF A TUMOR TO AN EPIGENETIC TREATMENT  
The present invention provides a method for determining the RES phenotype in a tumor. The present invention further provides a method for predicting the sensitivity of a tumor to an epigenetic...
US20110177970 METHODS FOR PREDICTING OR MONITORING WHETHER A PATIENT AFFECTED BY A CANCER IS RESPONSIVE TO A TREATMENT WITH A MOLECULE OF THE TAXOID FAMILY  
The present invention concerns in vitro methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family based on a...
US20140323342 Methods and Compositions for the Treatment and Diagnosis of Bladder Cancer  
The invention provides methods, compositions and kits for the detection and treatment of bladder cancer.
US20150152507 BIOMARKERS FOR PROSTATE CANCER  
The present application concerns methods and tools for diagnosing prostate cancer and furthermore concerns methods and tools for prognosing disease progression of prostate cancer. The method...
US20110144076 PRETERM DELIVERY DIAGNOSTIC ASSAY  
The present invention in one aspect relates generally to the identification, provision and use of a plurality of biomarkers to provide risk assessment of a woman for preterm delivery, and products...
US20150176072 MOLECULAR MALIGNANCY IN MELANOCYTIC LESIONS  
Disclosed are methods for determining whether a melanocyte-containing sample (such as a nevus or other pigmented lesion) is benign or a primary melanoma. These methods can include detecting (at...
US20140243219 METHODS AND SIGNATURES FOR OROPHARYNGEAL CANCER PROGNOSIS  
Methods for determining the prognosis of a subject with oropharyngeal squamous cell carcinoma are described, as well as miRNAs and panels of prognostic miRNAs that are used in the methods.
US20120289420 MICRORNA BIOMARKERS FOR AIRWAY DISEASES  
The present invention provides miRNA biomarkers useful for diagnosis, prognosis, and/or treatment of airway diseases such as asthma, asthma exacerbation and nasal polyps.
US20120277180 Cofactors and Methods for Use for Individuals  
Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of...
US20140206569 ENCODING OF MICROCARRIERS  
Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the...
US20120322677 PREDICTING BENEFIT OF ANTI-CANCER THERAPY VIA ARRAY COMPARATIVE GENOMIC HYBRIDIZATION  
Array comparative genomic hybridization classifiers, arrays comprising the classifiers, and related methods of using the same for predicting the therapeutic efficacy of anti-cancer therapy by...
US20100331209 MARKERS AND METHODS FOR ASSESSING AND TREATING SEVERE OR PERSISTANT ASTHMA AND TNF RELATED DISORDERS  
A method for assessment of the suitability of and/or effectiveness of a target therapy for a TNF-mediated-related disorder, such as severe or persistent asthma, in a subject evaluates the...
US20150211077 Methods and Systems for Determining a Likelihood of Adverse Prostate Cancer Pathology  
The present disclosure provides methods that find use in determining a likelihood of adverse prostate cancer pathology in a subject. The methods generally involve detection of one or more...
US20120052066 MARKERS AND METHODS FOR ASSESSING AND TREATING LUPUS PATIENTS SUSCEPTIBLE TO PHOTOPROVOCATION  
A method for predicting or detecting susceptibility to lupus of an individual subjected to photoprovocation obtains biological samples from the individual before and after exposure to...
US20120165228 EVOLVING NEW MOLECULAR FUNCTION  
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The present invention provides methods, compositions, and systems for...