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US20110319290 Methods and Compositions for Multiplex Sequencing  
Adapters are joined to target polynucleotides to create adapter-tagged polynucleotides. Adapter-tagged polynucleotides are sequenced simultaneously and sample sources are identified on the basis...
US20150252430 METHODS FOR THE IDENTIFICATION, ASSESSMENT, AND TREATMENT OF PATIENTS WITH CANCER THERAPY  
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are clinically responsive or non-responsive to a...
US20130013334 METHODS FOR THE IDENTIFICATION, ASSESSMENT, AND TREATMENT OF PATIENTS WITH CANCER THERAPY  
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are clinically responsive or non-responsive to a...
US20140235506 POLYNUCLEOTIDE BARCODE GENERATION  
The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including...
US20150087548 MARKER SEQUENCES FOR RHEUMATOID ARTHRITIS AND USE THEREOF  
The present invention relates to new marker sequences for rheumatoid arthritis and the diagnostic use thereof together with a method for screening of potential active substances for rheumatoid...
US20130053275 METHODS AND DEVICES FOR PREDICTING TREATMENT EFFICACY  
The present invention features methods, devices, and kits for predicting the sensitivity of a patient to a compound or medical treatment. The invention also features methods for identifying...
US20140303018 NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND NONALCOHOLIC STEATOHEPATITIS (NASH) BIOMARKERS AND USES THEREOF  
Methods, compositions, and kits for determining whether a subject has non-alcoholic fatty liver disease (NAFLD) are provided. Methods, compositions, and kits for determining whether a subject has...
US20130190192 Methods And Systems For Long Distance Tagging, Tracking, And Locating Using Wavelength Upconversion  
Methods and systems for plasmonically enhanced bionanoantennas for tagging, tracking, and locating targets of interest at long distances in both day and nighttime conditions. The nanoantennas are...
US20140100130 Methods and Compositions for the Diagnosis of Ovarian Cancer  
A diagnostic reagent or device comprises at least one ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker chloride intracellular...
US20140213485 Methods For Preparing cDNA From Low Quantities of Cells  
Methods for preparing cDNA libraries from single and low quantities of cells are disclosed. The methods are based on the principles of multi-strand displacement amplification or semi-random primed...
US20140330071 METHODS AND COMPOSITIONS FOR IMPROVED FERTILIZATION AND EMBRYONIC SURVIVAL  
Single nucleotide polymorphic sites of the bovine HSP genes are associated with improved fertilization rate and/or improved embryo survival rate in cattle. Nucleic acid molecules, kits, methods of...
US20130041209 METHODS AND COMPOSITIONS FOR IMPROVED FERTILIZATION AND EMBRYONIC SURVIVAL  
Single nucleotide polymorphic sites of the bovine HSP genes are associated with improved fertilization rate and/or improved embryo survival rate in cattle. Nucleic acid molecules, kits, methods of...
US20140206566 Methods and Compositions for Determining a Graft Tolerant Phenotype in a Subject  
Methods are provided for determining whether a subject has a graft tolerant phenotype. In practicing the subject methods, the expression of at least one gene in a sample from the subject, e.g., a...
US20150218656 METHODS FOR DETECTION AND DIAGNOSIS OF A LYMPHOID MALIGNANCY USING HIGH THROUGHPUT SEQUENCING  
Methods and compositions are provided for detection and diagnosis of a lymphoid malignancy using high throughput sequencing of rearranged T cell receptor DNA sequences.
US20130261019 NUCLEIC ACID NANOSTRUCTURE BARCODE PROBES  
Provided herein are, inter alia, barcode probes comprised of transiently or stably fhiorescently labeled nucleic acid nanostructures that are fully addressable and able to be read using standard...
US20150191792 GENE EXPRESSION PROFILE ASSOCIATED WITH PROSTATE CANCER  
Using an RT-PCR platform, detection of gene transcripts highly expressed in prostate tissue and expressed in peripheral blood mononuclear cells (PBMC) from patients with mCRPC can provide a more...
US20110306510 OPTIMIZED PPROBES AND PRIMERS AND METHODS OF USING SAME FOR THE DETECTION, SCREENING, ISOLATING AND SEQUENCING OF MRSA, MSSA STAPHYLOCOCCUS MARKERS, AND THE ANTIBIOTIC RESISTANCE GENE MEC A  
Described herein are primers and probes useful for the detection, screening, isolation and sequencing of MRSA, MSSA, Staphylococci markers, and the antibiotic resistance gene mecA.
US20110045997 METHOD AND PRODUCT FOR "IN VITRO" GENOTYPING WITH APPLICATIONS IN ANTI-AGEING MEDICINE  
The invention relates to an “in vitro” method for determining the global genetic risk a subject has of developing a pathology associated with aging. Said method is based on the combination of...
US20120178642 GENE EXPRESSION PROFILES ASSOCIATED WITH CHRONIC ALLOGRAFT NEPHROPATHY  
By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene...
US20140148357 Characterizing Gastro-Intestinal Disease  
A method for characterizing a gastro-intestinal disease in a subject involves comparing ratios of expression levels of genes in a biological sample from a subject to references, wherein the...
US20120058902 METHOD OF MEASURING ADAPTIVE IMMUNITY  
Compositions and methods for measuring adaptive immune receptor (T cell receptor and immunoglobulin) diversity are described, and find uses for assessing immunocompetence and other purposes. Means...
US20100009858 EMBRYONIC STEM CELL MARKERS FOR CANCER DIAGNOSIS AND PROGNOSIS  
A method of predicting the development of a cancer in a patient, comprises procuring a sample of tumour tissue from the patient, determining the expression pattern of embryonic stem cell genes in...
US20100184610 METHOD OF PROGNOSIS  
Provided are methods, kits and arrays for use in determining susceptibility to keloid formation. These determine susceptibility based on comparison of gene expression in a patient of interest with...
US20120071354 NORMALIZED NUCLEIC ACID LIBRARIES AND METHODS OF PRODUCTION THEREOF  
The present invention relates generally to methods for producing normalized nucleic acid libraries in which each member of the library can be isolated with approximately equivalent probability. In...
US20140274794 Methods and Compositions for Diagnosis of Ovarian Cancer  
Methods and compositions are provided for diagnosing ovarian cancer in a mammalian subject, preferably in a serum or plasma sample of a human subject. The methods and compositions enable the...
US20130202587 IDENTIFICATION OF GENETIC VARIANTS  
The present disclosure provides a method for identifying whether a subject is more or less likely to be responsive to VEGF-based therapy, comprising screening a nucleic acid sample obtained from...
US20130123124 METHODS AND COMPOSITIONS FOR CHARACTERIZING AUTISM SPECTRUM DISORDER BASED ON GENE EXPRESSION PATTERNS  
The invention relates to methods and kits for characterizing and diagnosing autism spectrum disorder in an individual based on gene expression levels.
US20130150250 RISK FACTORS OF CIGARETTE SMOKE-INDUCED SPIROMETRIC PHENOTYPES  
The technology provided herein relates to the SNPs identified as described herein, both singly and in combination, as well as to the use of these SNPs, and others in linkage disequilibrium with...
US20110130303 IN VITRO DIAGNOSIS/PROGNOSIS METHOD AND KIT FOR ASSESSMENT OF TOLERANCE IN LIVER TRANSPLANTATION  
In vitro diagnosis/prognosis method and kit, for assessment of tolerance in liver transplantation. The present invention refers to the study of peripheral blood transcriptional patterns from 80...
US20150038360 Method for Multiplex-Detecting Chronic Myelogenous Leukemia Gene Using Cleavable Probe  
One embodiment of the present invention provides a detection kit for detecting a chronic myelogenous leukemia (CML) gene expression, wherein the detection kit includes a primer set which is...
US20110053792 MICROARRAY FOR EXPRESSION ANALYSIS OF CELLULAR GLYCOSYLATION MECHANISM  
The present invention relates to a support onto which a set of probes is applied wherein the set comprises: (a) probes capable of specifically hybridising with nucleic acids encoding...
US20130023426 Methods of Detecting Signatures of Disease or Conditions in Bodily Fluids  
Methods and compositions for diagnosing the presence of a cancer cell in an individual are provided. Methods and compositions for identifying a tumor-specific signature in an individual having...
US20110230363 METHODS, KITS, AND COMPOSITIONS USEFUL IN SELECTING AN ANTIBIOTIC TO TREAT MRSA  
The present invention provides a method, a kit and composition for determining MRSA and other Staphylococcus strain resistance to one or more antibiotic agents through detecting the presence of...
US20120220488 HEART AGING BIOMARKERS AND METHODS OF USE  
The invention provides a set of robust biomarkers of aging in the heart comprising several genes involved in the Wnt signaling pathway. These genes have been found to be down-regulated in aged...
US20130296183 FUNCTIONAL GENOMICS ASSAY FOR CHARACTERIZING PLURIPOTENT STEM CELL UTILITY AND SAFETY  
The present invention generally relates set of reference data or “scorecard” for a pluripotent stem cell, and methods, systems and kits to generate a scorecard for predicting the functionality and...
US20150197792 DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER  
The present invention provides a family of dark quenchers, termed Black Hole Quenchers (“BHQs”), that are efficient quenchers of excited state energy but which are themselves substantially...
US20150031557 DETECTION OF SHIGA TOXIN GENES IN BACTERIA  
The disclosed invention is related to methods, compositions and kits for targeting nucleic acid derived from Shiga toxin-producing bacteria such as E. coli. Compositions include amplification...
US20120165229 OPTIMIZED PROBES AND PRIMERS AND METHODS OF USING SAME FOR THE DETECTION, SCREENING, ISOLATION AND SEQUENCING OF MRSA, MSSA, STAPHYLOCOCCUS MARKERS, AND THE ANTIBIOTIC RESISTANCE GENE MEC A  
Described herein are primers and probes useful for the detection, screening, isolation and sequencing of MRSA, MSSA, Staphylococci markers, and the antibiotic resistance gene mecA.
US20130005602 METHOD FOR EVALUATING THE SENSITIZING POTENTIAL OF A TEST COMPOUND  
The invention relates to a method for evaluating the sensitizing potential of a test compound, and to a kit for implementing said method.
US20100298161 BIOMARKERS FOR LIVER INJURY  
Fourteen markers not previously known to be associated with liver injury have been identified. Methods to diagnose a subject for liver injury using these markers are described.
US20150240304 GENES AND GENES COMBINATIONS BASED ON GENE MKNK1 PREDICTIVE OF EARLY RESPONSE OR NON RESPONSE OF SUBJECTS SUFFERING FROM INFLAMMATORY DISEASE TO CYTOKINE TARGETING DRUGS (CYTD) OR ANTI-INFLAMMATORY BIOLOGICAL DRUGS  
This invention refers to the field of human medicine and specifically to the diagnosis/prognosis of the responsiveness to a cytokine targeting drug (Cy TD) or an anti-inflammatory biological drug...
US20120046261 COMPOSITIONS AND METHODS FOR DIAGNOSING AND PREVENTING SPONTANEOUS PRETERM BIRTH  
Disclosed herein are compositions and methods of identifying a subject at risk for preterm birth and selecting effective therapies for preventing preterm birth in the subject. The disclosed...
US20120258885 Systems and Methods for Individualized Functional Genomic Profiling Related to Cancer Cell Growth  
The present invention provides systems and methods for identification of genes related to cancer cell growth. In particular, the present invention provides functional genomic profiling of primary...
US20150038369 Method and Kit for Diagnosing Autism Using Gene Expression Profiling  
This invention relates to DNA microarray technology, and more specifically to methods and kits for identifying autism and autism spectrum disorders in humans.
US20120015838 Method and Kit for Diagnosing Autism Using Gene Expression Profiling  
This invention relates to DNA microarray technology, and more specifically to methods and kits for identifying autism and autism spectrum disorders in humans.
US20150247204 DIFFERENTIAL DIAGNOSIS OF HEPATIC NEOPLASMS  
Methods for making a differential diagnosis of hepatic neoplasms, e.g., tumors, and for identifying metastatic tumors of hepatic origin, based on detection of levels of albumin mRNA. The methods...
US20110124712 ANTI-CANCER COMPOSITION COMPRISING MICRORNA MOLECULES  
Disclosed is an anticancer composition for the treatment of hypoxia-induced angiogenesis-associated diseases including cancers. It comprises a microRNA-125 nucleic acid molecule. Also, methods of...
US20130040846 Signatures for Kidney Aging  
Sets of genes associated with aging in the kidney are identified herein, and methods of assessing the health and longevity of the kidney in a human subject are disclosed. Methods include obtaining...
US20110237454 MARKER FOR DIAGNOSIS OF EXPOSURE TO ELECTROMAGNETIC RADIATION AND DIAGNOSTIC KIT COMPRISING THE SAME  
Disclosed are a composition for the diagnosis of exposure to electromagnetic radiation, comprising an agent capable of measuring the expression level of the diagnostic marker, a diagnosis kit...
US20110237453 MARKER FOR DIAGNOSIS OF EXPOSURE TO ELECTROMAGNETIC RADIATION AND DIAGNOSTIC KIT COMPRISING THE SAME  
Disclosed are a composition for the diagnosis of exposure to electromagnetic radiation, comprising an agent capable of measuring the expression level of the diagnostic marker, a diagnosis kit...