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US20120172240 GENETIC POLYMORPHISMS ASSOCIATED WITH ADVANCED LUNG DISEASES  
The present invention relates to methods and compositions that may be used to predict the risk of an individual, for example a smoker, for developing chronic obstructive pulmonary disease...
US20140066328 PREDICTING GASTROENTEROPANCREATIC NEUROENDOCRINE NEOPLASMS (GEP-NENs)  
Described are embodiments related to gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) biomarkers and agents, systems, and kits for detecting the same, and associated GEP-NEN diagnostic,...
US20140018256 METHOD OF DIAGNOSING AUTISM SPECTRUM DISORDER  
The present invention provides a method for diagnosing an autism spectrum disorder (ASD), or predisposition to develop an ASD, in a subject, which comprises the step of investigating a set of...
US20130261196 Nucleic Acids For Multiplex Organism Detection and Methods Of Use And Making The Same  
The invention provides mixtures of linear nucleic acid probes, including circularizing “capture” probes, capable of massively multiplex capture of one or more sequences of interest from a...
US20150105291 METHOD, KIT, AND APPARATUS FOR EVALUATING ISCHEMIC HEART DISEASE  
It is intended to evaluate an ischemic heart disease with high accuracy by convenient operation. The method for evaluating an ischemic heart disease according to the present invention comprises...
US20140005064 POLYMORPHISMS IN ANGIOGENESIS PATHWAY GENES ASSOCIATED WITH TUMOR RECURRENCE IN SURGERY TREATED CANCER PATIENTS  
This invention provides compositions and methods for determining the likely tumor recurrence of cancer patients after surgical resection. Said methods are based on determining the patient's...
US20120108441 POLYMORPHISMS IN ANGIOGENESIS PATHWAY GENES ASSOCIATED WITH TUMOR RECURRENCE IN SURGERY TREATED CANCER PATIENTS  
This invention provides compositions and methods for determining the likely tumor recurrence of cancer patients after surgical resection. Said methods are based on determining the patient's...
US20130085083 SUBSTANTIALLY NON-SELF COMPLEMENTARY PRIMERS  
The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is...
US20130209447 METHODS AND KITS FOR PREDICTING THE RISK OF DIABETES ASSOCIATED COMPLICATIONS USING GENETIC MARKERS AND ARRAYS  
A method for diagnosing a genetic predisposition in a subject for diseases, disorders or conditions including a diabetic kidney complication such as kidney disease of type 2 diabetes or type 1...
US20150141270 SINGLE-STRANDED NUCLEIC ACID APTAMERS SPECIFICALLY BINDING TO KLEBSIELLA PNEUMONIAE AND METHOD FOR DETECTING K. PNEUMONIA USING THE SAME  
Provided is a single-stranded nucleic acid aptamer specifically binding to Klebsiella pneumoniae, and a method for detecting Klebsiella pneumoniae by using the same. The aptamer of the present...
US20130252851 METHOD OF MAKING A PAIRED TAG LIBRARY FOR NUCLEIC ACID SEQUENCING  
The present disclosure relates to methods and compositions for making paired tags and paired tag libraries.
US20120004136 MSH2 AND ADJUVANT CISPLATIN-BASED CHEMOTHERAPY IN NON-SMALL-CELL LUNG CANCER  
The invention is generally directed to a diagnostic method for predicting the benefit of the response of a subject diagnosed with cancer to a platinum compound-based adjuvant chemotherapy,...
US20150167064 COMPOSITIONS AND METHODS FOR MULTIPLEX BIOMARKER PROFILING  
Provided herein are compositions and methods for identifying or quantitating one or more analytes in sample. The composition can comprise an affinity molecule reversibly conjugated to a label...
US20150159204 Single Molecule Arrays for Genetic and Chemical Analysis  
Random arrays of single molecules are provided for carrying out large scale analyses, particularly of biomolecules, such as genomic DNA, cDNAs, proteins, and the like. In one aspect, arrays of the...
US20150057173 METHODS FOR DETERMINING THE TROPISM AND RECEPTOR USAGE OF A VIRUS, IN PARTICULAR HIV, IN BODY SAMPLES TAKEN FROM THE CIRCULATION  
The present invention relates to microarrays, sets of primers and methods for determining the co-receptor usage of a virus, in particular whether HIV uses CXCR4 or CCR5 as co-receptor. The methods...
US20130005607 QUALITY CONTROL OF AGRICULTURAL PRODUCTS BASED ON GENE EXPRESSION  
The invention relates to the field of quality testing of fresh plant-based and mushroom based products. Methods, carriers and kits for determining the quality stage are provided.
US20110294688 QUALITY CONTROL OF AGRICULTURAL PRODUCTS BASED ON GENE EXPRESSION  
The invention relates to the field of quality testing of fresh plant-based and mushroom based products. Methods, carriers and kits for determining the quality stage are provided.
US20140086836 METHOD FOR DETECTION OF A NEUROLOGICAL DISEASE  
The present invention provides methods for predicting whether a subject will develop a disease capable of affecting cognitive function. More specifically, the present invention relates to the...
US20120004855 METHYLATION BIOMARKERS FOR PREDICTING RELAPSE FREE SURVIVAL  
A methylation classification list comprising loci DNA, for which loci the methylation status of the DNA is indicative of likelihood of recurrence of cancer, is provided. Furthermore, a method,...
US20140228253 COMPOSITIONS AND METHODS FOR INFLUENCING SATIETY, LIPID METABOLISM, AND FAT UTILIZATION  
The invention provides (1) genes differentially expressed in animals administered fatty acid amides that affect one or more of food intake, satiety, lipid metabolism, and fat utilization and (2)...
US20120190577 PROCESSES AND METHODS FOR DIAGNOSIS OF ALZHEIMER'S DISEASE  
The present application relates to methods and compositions that can be used to diagnose Alzheimer's disease in mammals, most notably humans. Ti describes most notably peripheral blood biomarkers...
US20150218655 BIOMARKERS FOR PROSTATE CANCER PROGNOSIS  
Described are embodiments related to prostate cancer biomarkers, agents, and systems for detecting and targeting the same, and associated prostate cancer diagnostic and prognostic methods.
US20150152486 METHOD OF IN VITRO DIAGNOSING A PELLICULAR STATE IN A SUBJECT AND RELATED APPLICATIONS  
The present invention relates to a method of diagnosing a pellicular state in a subject, to a screening method of identifying an antidandruff agent, and to kits and nucleic acid arrays useful for...
US20140057797 Methods for Detecting an increased risk for coronary heart disease  
The invention relates generally to an allele on human chromosome 9 associated with increased risk for coronary heart disease and the use or detection of such an allele in determining whether a...
US20130203615 ANTIANDROGEN THERAPY MONITORING METHODS AND COMPOSITIONS  
The present invention provides methods of evaluating the effectiveness of an antiandrogen therapy in a human by comparing the pre- and post antiandrogen treatment levels of an androgen modulated...
US20140342935 BASE FOR USE IN AMPLIFICATION OF NUCLEIC ACID AND METHOD FOR AMPLIFYING NUCLEIC ACID  
The present invention is to provide a base for use in the amplification of a nucleic acid, which makes it possible to accurately and effectively amplify and detect a plurality of target nucleic...
US20150087555 METHOD FOR IMMOBILIZING BIOLOGIC MOLECULES ON SOLID SURFACES  
The invention provides a method for immobilization of biological molecules such as nucleic acids, peptides and proteins onto the surface of a glass or plastic solid support.
US20110263439 MARKERS ASSOCIATED WITH ALZHEIMER'S DISEASE  
This application discloses SNPs capable of predicting increased or decreased risk of developing late onset Alzheimer's disease.
US20150017651 PERSONALIZED MEDICINE FOR THE PREDICTION OF THERAPY TARGETING THE HEDGEHOG PATHWAY  
Methods and composition for tumor therapy, especially esophageal adenocarcinoma (EAC), are described. For example, in certain aspects methods for determining Hedgehog and mTOR signaling pathway...
US20140235472 METHODS AND COMPOSITIONS FOR THE DETECTION OF BALANCED RECIPROCAL TRANSLOCATIONS/REARRANGEMENTS  
Disclosed are methods and compositions related to the detection of balanced reciprocal translocations/rearrangements and determination of the location of said balanced reciprocal...
US20130217591 Marker Sequences for Inflammatory Prostate Diseases, Prostate Carconoma and Their Use  
The present invention relates to novel marker sequences for inflammatory prostate diseases, prostate carcinoma and the diagnostic use thereof together with a method for screening of potential...
US20130035314 METHODS AND KITS FOR DETECTING RISK FACTORS FOR DEVELOPMENT OF JAW OSTEONECROSIS AND METHODS OF TREATMENT THEREOF  
Methods of and kits for determining the pharmacogenetic, pharmacokinetic and cellular basis of bisphosphonate-induced osteonecrosis of the jaw (BONJ) involve associating particular proteins and...
US20120283130 METHOD FOR SCREENING INDUCED PLURIPOTENT STEM CELLS  
The present invention relates to miRNA or genes expressed in induced pluripotent stem cells, and a method for screening for induced pluripotent stem cells having functions equivalent to those of...
US20150141257 SEQUENCE CAPTURE METHOD USING SPECIALIZED CAPTURE PROBES (HEATSEQ)  
The present invention is a novel protocol for the massively parallel production of improved MIPs. The molecular improvements to the MIP cover the manufacturing of the probes, the workflow, the...
US20150225786 CHROMOSOME CONFORMATION CAPTURE IN PARTITIONS  
Methods compositions and kits are provided for performing a chromatin or chromosome conformation capture assay in partitions.
US20140189898 RESISTANCE TO BACTERIAL INFECTION  
The present invention provides a method of identifying an animal having a genotype associated with resistance to bacterial infection comprising the steps of: (a) providing a sample from said...
US20150225789 HAPLOTYING OF HLA LOCI WITH ULTRA-DEEP SHOTGUN SEQUENCING  
Methods are provided to determine the entire genomic region of a particular HLA locus including both intron and exons. The resultant consensus sequences provides linkage information between...
US20120329678 Method for Making Mate-Pair Libraries  
The present disclosure provides methods for generating mate-pair libraries using a recombinase/recombination site system. The method allows for increased insert size, improved efficiency and...
US20140234289 EVALUATION AND IMPROVEMENT OF NUCLEASE CLEAVAGE SPECIFICITY  
Engineered nucleases (e.g., zinc finger nucleases (ZFNs), transcriptional activator-like effector nucleases (TALENs), and others) are promising tools for genome manipulation and determining...
US20120157347 METHOD FOR HLA TYPING  
A method for the identification of DNA sequence elements in complex and highly variable sequences is described. The method considist of identifying a short sequence element of several DNA bases...
US20120277110 PARP AND ADJUVANT CISPLATIN-BASED CHEMOTHERAPY IN NON-SMALL-CELL LUNG CANCER  
The invention is generally directed to a diagnostic method for predicting the benefit of the response of a subject diagnosed with cancer to a platinum compound-based adjuvant chemotherapy,...
US20120065095 MARKERS OF RENAL TRANSPLANT REJECTION AND RENAL DAMAGE  
The present invention relates to methods of detecting renal transplant rejection and other forms of renal damage. Protein markers or renal damage are provided, along with assays for detecting said...
US20140342936 METHODS AND KITS FOR DIAGNOSING LATENT TUBERCULOSIS INFECTION  
The present invention relates to a method for diagnosing latent tuberculosis infection in a subject comprising the step i) consisting of incubating a biological sample obtained from the subject...
US20120225047 NUTRIGENETIC BIOMARKERS FOR OBESITY AND TYPE 2 DIABETES  
The present invention discloses genes, SNP markers and haplotypes of susceptibility or predisposition to obesity, type 2 diabetes (T2D) and subdiagnosis of obesity and T2D and related medical...
US20140057805 DNA-ORIGAMI-BASED STANDARD  
Arrays which utilize labeling molecules for calibrating a measuring device, such as microscopes, have a first structure based on a DNA origami as a calibration sample, wherein the DNA origami is...
US20140045728 Orthogonal Amplification and Assembly of Nucleic Acid Sequences  
Methods and compositions for synthesizing nucleic acid sequences of interest from heterogeneous mixtures of oligonucleotide sequences are provided.
US20110281764 SCREENING ASSAYS AND METHODS  
Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with...
US20150133414 COMPOSITIONS AND METHODS FOR IDENTIFYING AND DIAGNOSING SALT SENSITIVITY OF BLOOD PRESSURE  
It was determined whether SNPs in SLC4A5 are associated with salt sensitivity of blood pressure (BP). Subjects consumed an isocaloric constant diet with a randomized order of 7 days low Na+ (10...
US20140235495 CELL RESPONSE ASSAY FOR CANCER AND METHODS OF PRODUCING AND USING SAME  
A cell response assay for cancer is provided. In the assay, the levels of a cancer cell type biomarker, a chemo resistance biomarker and a metastatic potential biomarker are simultaneously...
US20150225775 PCR PRIMERS  
The present disclosure provides methods, compositions, and kits for performing PCR (including multiplex PCR). The methods, compositions and kits provided herein use one or more primer pairs that...